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Chul-Hoon Kwon

Sungkyunkwan University · Medicine

About the Lab

Professor Chul-Hoon Kwon's research lab specializes in urological oncology and genitourinary diseases, with a focus on prostate cancer, benign prostatic hyperplasia (BPH), and rare urological conditions such as Wilms’ tumor in congenital anomalies. The lab investigates clinical and molecular predictors of disease progression, particularly in patients with persistent elevated PSA despite negative initial biopsies, and explores the role of systemic therapies—such as statins—in modulating disease markers and symptoms. The lab also contributes to the development of preclinical models, including murine bladder tumor models, to support translational research in urological cancers.

prostate cancerbenign prostatic hyperplasiaurinary tract infectionbiopsy predictionurological oncology

Research Overview

Papers
35
Total Citations
66
Papers (5y)
17
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
17total
2012
2013
2014
2015
2016
Citations per year (5y)
59total
20122013201420152016

Selected Papers

15
1
Article|20 citations·2013
Tuberculosis of testis and prostate that mimicked testicular cancer in young male soccer player
Young Sam Cho, Kwan Joong Joo, Chil Hun Kwon, Heung Jae Park
SJR Q2Journal of Exercise RehabilitationOA

Staphylococcus infection was the most common organism found in infection of athletics, and tuberculosis (TB) was rare. Although genitourinary tuberculosis (GUTB) was the most common subtype of extrapulmonary tuberculosis (EPTB) in the past, it was recently reported to account for less than 0.5% of all patients with EPTB and 1.5% of all patients with pulmonary tuberculosis (TB). And, there are few cases reported about concomitant tuberculous infection of testis and prostate. Pubic pain is a commo

SurgeryMedicine
2
Article|15 citations·2012
Wilms' Tumor in a Horseshoe Kidney
Sanghun Lee, Min Ho Bae, Sung Ho Choi, Jin Seok Lee, Young Sam Cho, Kwan Joong Joo, Chil Hun Kwon, Heung Jae Park
Korean journal of urologyOA

The incidence of horseshoe kidney is about 1 in 400 cases. The presence of Wilms' tumor with a horseshoe kidney is unusual, and the occurrence of Wilms' tumor in a horseshoe kidney is estimated at 0.4 to 0.9% of all Wilms' tumors. We report the case of a 5-year-old boy who presented with a stage IV Wilms' tumor in a horseshoe kidney. The patient was treated with preoperative chemotherapy followed by surgical resection and adjuvant chemotherapy. This case illustrates the role of preoperative chem

Molecular BiologyBiochemistry, Genetics and Molecular Biology
3
Article|15 citations·2013
Impact of Treatment With Statins on Prostate-Specific Antigen and Prostate Volume in Patients With Benign Prostatic Hyperplasia
Sang Hun Lee, Tae Ju Park, Min Ho Bae, Sung Ho Choi, Young Sam Cho, Kwan Joong Joo, Chil Hun Kwon, Heung Jae Park
Korean journal of urologyOA

Statin administration reduced PSA and PV in BPH patients. This finding may imply the improvement of lower urinary tract symptoms and prevention of cardiovascular disease and chemoprevention of prostate cancer with statin treatment.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
4
Article|5 citations·2012
Tumor Establishment Features of Orthotopic Murine Bladder Cancer Models
Jin Seok Lee, Min Ho Bae, Sung Ho Choi, Sang‐Hun Lee, Young Sam Cho, Heung Jae Park, Chil Hun Kwon, Kwan Joong Joo
Korean journal of urologyOA

The HCl pretreatment model was a preferable murine bladder tumor model for evaluating further therapeutic interventions.

SurgeryMedicine
5
Article|2 citations·2015
Effects of Diabetes Mellitus and HbA1c on Treatment Prognosis in Uncomplicated Acute Pyelonephritis
Min Ho Bae, Chang Hoo Park, Young Sam Cho, Kwan Joong Joo, Chil Hun Kwon, Heung Jae Park
The Korean Journal of Urogenital Tract Infection and InflammationOA

Purpose We investigated potential difference in the clinical features of hospitalized female acute pyelonephritis (APN) patients with and without diabetes mellitus (DM). The additional purpose of the study was to determine whether HbA1c has a role in predicting clinical outcome in terms of morbidity compared with those considered to have normal glycemic control in female APN patients with DM. Materials and Methods Among the female patients who received inpatients care due to APN from January 201

EpidemiologyMedicine
6
Article|1 citations·2011
Clinical Predictive Factors in Patients with Prostate Cancer Diagnosed by Repeat Prostate Biopsy
Kwan Joong Joo, Chil Hun Kwon
Korean Journal of Andrology

= Abstract = Purpose: We investigated the predictive factors in patient with prostate cancer diagnosed by repeat prostate biopsy, where initial prostate biopsy results were negative for malignancy. Materials and Methods: Between March 2000 and June 2007, 1280 men with suspected prostatic cancer underwent transrectal ultrasound guided needle biopsy of the prostate, with 148 (11.6%) diagnosed as having prostate cancer. Of 1132 men whose biopsy results were negative for malignancy, 655 whose prosta

Pulmonary and Respiratory MedicineMedicine
7
Article|1 citations·2011
재생검을 통해 전립선암으로 진단받은 환자의 임상적 예측요인
주관중, 권칠훈

Purpose: We investigated the predictive factors in patient with prostate cancer diagnosed by repeat prostate biopsy, where initial prostate biopsy results were negative for malignancy. Materials and Methods: Between March 2000 and June 2007, 1280 men with suspected prostatic cancer underwent transrectal ultrasound guided needle biopsy of the prostate, with 148 (11.6%) diagnosed as having prostate cancer. Of 1132 men whose biopsy results were negative for malignancy, 655 whose prostate specific a

8
Article|1 citations·2015
여성 단순 급성 신우신염 환자에서 당뇨 및 당화혈색소가 치료 경과에 미치는 영향
배민호, 박창후, 조영삼, 주관중, 권칠훈, 박흥재

Purpose: We investigated potential difference in the clinical features of hospitalized female acute pyelonephritis (APN) patients with and without diabetes mellitus (DM). The additional purpose of the study was to determine whether HbA1c has a role in predicting clinical outcome in terms of morbidity compared with those considered to have normal glycemic control in female APN patients with DM.Materials and Methods: Among the female patients who received inpatients care due to APN from January 20

9
Article|1 citations·2006
혈청 PSA가 증가된 환자에서 생검부위 및 생검수에 따른 전립선암 진단율 비교
안흥석, 권칠훈, 주관중
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0358320060470060591
10
Article|1 citations·2004
백서에서 신부전 모델의 개발
조영삼, 권칠훈, 박흥재
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0358320040450060592

Purpose: An animal model with experimental uremia is an important research tool for the study of pathophysiological events that take place during chronic renal failure. Among the several techniques of making uremic models, the two-stage 5/6 nephrectomized rat model is the most popular method, but this modality has some disadvantages. The aim of this study was to simplify the complicated method for experimental uremic animal models in the rat. Materials and Methods: Forty Sprague-Dawley rats were

11
Article|1 citations·2008
Lymphoepithelioma-like Carcinoma of Renal Pelvis
함영일, 주관중, 임성진, 심영진, 박경서, 손진희, 권칠훈, 박흥재

Lymphoepithelioma was originally described as a neoplasm in the nasopharynx. Tumors with histologic features similar to those of nasopharyngeal lymphoepithelioma have been identified in anatomic sites other than the nasopharynx, such as the salivary gland, lung, thymus and stomach; these tumors have been termed lymphoepithelioma-like carcinoma(LELC). The etiology and pathogenesis of this neoplasm in the renal pelvis is not clear. We have experienced a case of lymphoepithelioma-like carcinoma of

12
Article|1 citations·2012
Wilms’ Tumor in a Horseshoe Kidney
이상훈, 배민호, 최성호, 이진석, 조영삼, 주관중, 권칠훈, 박흥재

The incidence of horseshoe kidney is about 1 in 400 cases. The presence of Wilms’ tumor with a horseshoe kidney is unusual, and the occurrence of Wilms’ tumor in a horseshoe kidney is estimated at 0.4 to 0.9% of all Wilms’ tumors. We report the case of a 5-year-old boy who presented with a stage IV Wilms’ tumor in a horseshoe kidney. The patient was treated with preoperative chemotherapy followed by surgical resection and adjuvant chemotherapy. This case illustrates the role of preoperative chem

13
Article|1 citations·2005
5세 소아에서 발생한 방광요로상피종양
문홍철, 안흥석, 박종규, 심영진, 박흥재, 권칠훈, 주관중
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0358320050460090998

The occurrence of bladder tumors in the first 2 decades of life are rare neoplasias. Transitional cell tumors of the bladder are extremely a rare clinical disease entity. Here, a case of a papillary urothelial tumor in a 5-year-old girl is reported, with a brief review of the literature. Histologically, the tumor was a solitary and papillary urothelial tumor of low malignant potential(by WHO and the ISUP).

14
Article|1 citations·2006
Comparative Analysis of the Prostate Cancer Detection Rate according to Region and Number of Biopsy in Patient with Elevated Serum PSA
Heung Seok Ahn, Chil Hun Kwon, Kwan Joong Joo
Korean Journal of UrologyOA

Purpose: We evaluated the rate of prostate cancer detection according to the region and number of biopsies in patients with an elevated level of serum prostate-specific antigen (PSA). Materials and Methods: Transrectal ultrasound (TRUS) guided prostate biopsies were performed at 12 regions, using the standard sextant, with an additional 6 cores from the far lateral peripheral zone, in 178 men with an elevated PSA level, and with no suspicious lesions of prostate cancer on digital rectal examinat

Pulmonary and Respiratory MedicineMedicine
15
Article|0 citations·2005
요관에 발생한 자궁내막증
권칠훈, 주관중, 박흥재, 안흥석, 박종규, 심영진

Endometriosis represents extrauterine nonneoplastic endometrial tissue. It is most commonly diagnosed in women of childbearing age, with a peak age of 40 to 44 years. The incidence of genitourinary involvement ranges from 1% to 2%. Ureteral endometriosis is a rare entity, and its diagnosis requires a high index of suspicion. We report a case of ureteral endometriosis in a 44-year-old multiparous woman with a brief review of literature. (J. Korean Continence Society 2005;9:142-145)

Research Areas

Pulmonary and Respiratory MedicineSurgeryCancer ResearchEpidemiologyPhysiologyUrology

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