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Chul-woong Yoo

Korea University · Medicine

About the Lab

Professor Chul-woong Yoo's research lab specializes in interventional cardiology and cardiovascular imaging, with a focus on improving the diagnosis, risk stratification, and percutaneous treatment of complex coronary artery disease. The lab investigates biomarkers and imaging modalities—such as coronary CT angiography, optical coherence tomography, and inflammatory markers—to enhance the prediction of procedural outcomes and plaque vulnerability in acute coronary syndromes. Key research directions include optimizing percutaneous coronary intervention (PCI) strategies for challenging lesions like chronic total occlusions (CTO), in-stent restenosis, and complex coronary anatomy, particularly in real-world and high-risk populations. The lab also explores the impact of comorbid conditions such as thyroid dysfunction and atrial fibrillation on interventional outcomes and bleeding risk.

coronary CTOinterventional cardiologybiomarkerscoronary CT angiographyacute coronary syndrome

Research Overview

Papers
291
Total Citations
3,244
Papers (5y)
113
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
113total
2022
2023
2024
2025
2026
Citations per year (5y)
415total
20222023202420252026

Selected Papers

15
1
Article|84 citations·2017
Coronary Computed Tomography Angiography Predicts Guidewire Crossing and Success of Percutaneous Intervention for Chronic Total Occlusion
Cheol Woong Yu, Hyun‐Jong Lee, Jon Suh, Nae-Hee Lee, Sang‐Min Park, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Joo‐Yong Hahn, Seung‐Hyuk Choi, Hyeon‐Cheol Gwon, Sanghoon Lee
SJR Q1Circulation Cardiovascular ImagingOA

Background— We developed a model that predicts difficulty of percutaneous coronary intervention for coronary chronic total occlusion (CTO) using coronary computed tomographic angiography. Methods and Results— A total of 684 CTO lesions with preprocedural computed tomographic angiography were enrolled from 4 centers. Data were randomly divided into derivation and validation datasets at 2:1 ratio. The end point was successful guidewire crossing ≤30 minutes, which was met in 50%. The KCCT (Korean M

SurgeryMedicine
2
Article|71 citations·2015
Long-Term Clinical Outcomes of Final Kissing Ballooning in Coronary Bifurcation Lesions Treated With the 1-Stent Technique
Cheol Woong Yu, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Seung‐Hyuk Choi, Jin Ho Choi, Hyun‐Jong Lee, Ju Hyeon Oh, Bon‐Kwon Koo, Seung‐Woon Rha, Jin‐Ok Jeong, Myung Ho Jeong
SJR Q1JACC: Cardiovascular Interventions
SurgeryMedicine
3
Article|34 citations·2019
A comparison of procedural success rate and long-term clinical outcomes between in-stent restenosis chronic total occlusion and de novo chronic total occlusion using multicenter registry data
Seung Hun Lee, Jae Young Cho, Je Sang Kim, Hyun‐Jong Lee, Jeong Hoon Yang, Jae Hyoung Park, Soon Jun Hong, Rak Kyeong Choi, Seung‐Hyuk Choi, Hyeon‐Cheol Gwon, Do‐Sun Lim, Cheol Woong Yu
SJR Q1Clinical Research in CardiologyOA

BACKGROUND: There have been little data about outcomes of percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) chronic total occlusion (CTO) in the drug eluting stent (DES) era. This study aimed to compare the procedural success rate and long-term clinical outcomes of ISR CTO and de novo CTO. METHODS AND RESULTS: Patients who underwent PCI for ISR CTO (n = 164) versus de novo CTO (n = 1208) were enrolled from three centers in Korea between January 2008 and December 2014. Among

SurgeryMedicine
4
Article|28 citations·2018
Trends and Outcomes of Transcatheter Aortic Valve Implantation (TAVI) in Korea: the Results of the First Cohort of Korean TAVI Registry
Cheol Woong Yu, Won‐Jang Kim, Jung‐Min Ahn, Hyungdon Kook, Se Hun Kang, Jung‐Kyu Han, Young-Guk Ko, Seung-Hyuk Choi, Bon‐Kwon Koo, Kiyuk Chang, Hyo-Soo Kim
SJR Q2Korean Circulation JournalOA

K-TAVI registry showed favorable 1-year outcomes with decreasing complication rate over time in real-world Korean patients. Two-thirds of patients were low to intermediate surgical risk and showed a significantly lower mortality than the high-risk patients, suggesting the promising future on the expanded indications of TAVI.

Cardiology and Cardiovascular MedicineMedicine
5
Article|24 citations·2020
Identification of plaque ruptures using a novel discriminative model comprising biomarkers in patients with acute coronary syndrome
Hyungdon Kook, Duck Hyun Jang, Jong-Ho Kim, Jaeyoung Cho, Hyung Joon Joo, Sang-A Cho, Jae Hyoung Park, Soon Jun Hong, Cheol Woong Yu, Do‐Sun Lim
SJR Q1Scientific ReportsOA

Soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1), neutrophil gelatinase-associated lipocalin (NGAL), and matrix metalloproteinase-9 (MMP-9) are inflammatory biomarkers involved in plaque destabilization resulting in acute coronary syndrome (ACS). This study aimed to investigate the diagnostic value of a combination of biomarkers to discriminate plaque ruptures in the setting of ACS. Eighty-five ACS patients with optical coherence tomography (OCT) images of the culprit pla

SurgeryMedicine
6
Article|23 citations·2020
Drug Eluting Stent vs. Drug Coated Balloon for Native Femoropopliteal Artery Disease: A Two Centre Experience
Yong-Joon Lee, Hyungdon Kook, Young‐Guk Ko, Cheol Woong Yu, Hyung Joon Joo, Chul‐Min Ahn, Donghoon Choi
SJR Q1European Journal of Vascular and Endovascular SurgeryOA
SurgeryMedicine
7
Article|21 citations·2015
Triple antithrombotic therapy versus dual antiplatelet therapy in patients with atrial fibrillation undergoing drug-eluting stent implantation
Dong Oh Kang, Cheol Woong Yu, Hee Dong Kim, Jae Young Cho, Hyung Joon Joo, Rak Kyong Choi, Jin-Sik Park, Hyun‐Jong Lee, Je Sang Kim, Jae Hyung Park, Soon Jun Hong, Do‐Sun Lim
SJR Q3Coronary Artery Disease

In AF patients undergoing DES implantation, prolonged administration of TAT may be harmful due to the substantial increase in the risk for major bleeding without any reduction in MACCE.

Cardiology and Cardiovascular MedicineMedicine
8
Article|14 citations·2014
A comparison of clinical features of coronary artery spasm with and without thyrotoxicosis
Soo Youn Lee, Cheol Woong Yu, Young Jin Choi, Rak Kyeong Choi, Jin-Sik Park, Hyun‐Jong Lee, Je Sang Kim, Ho Jun Jang, Duck Hyun Jang, Myung Joon Chae, Won Heum Shim, Young Moo Ro
SJR Q3Coronary Artery Disease

Clinical and angiographic presentations of CAS with thyrotoxicosis were more severe than CAS without thyrotoxicosis, but clinical outcomes were similar in both groups. Optimal vasodilator therapy is essential for the management of CAS with thyrotoxicosis. Thyroid function test should be mandatory for all patients with CAS.

Radiology, Nuclear Medicine and ImagingMedicine
9
Article|12 citations·2013
Cardiovascular event rates in patients with ST-elevation myocardial infarction were lower with early increases in mobilization of Oct4highNanoghigh stem cells into the peripheral circulation during a 4-year follow-up
Cheol Woong Yu, Seung‐Cheol Choi, Soon Jun Hong, Ji-Hyun Choi, Chi‐Yeon Park, Jong-Ho Kim, Jae Hyoung Park, Chul‐Min Ahn, Do‐Sun Lim
SJR Q1International Journal of Cardiology
Cardiology and Cardiovascular MedicineMedicine
10
Article|10 citations·2023
Predictors of in-hospital mortality after successful weaning of venoarterial extracorporeal membrane oxygenation in cardiogenic shock
Joo Hee Jeong, Hyungdon Kook, Seung Hun Lee, Hyung Joon Joo, Jae Hyoung Park, Soon Jun Hong, Mi‐Na Kim, Seong‐Mi Park, Jae Seung Jung, Jeong Hoon Yang, Hyeon‐Cheol Gwon, Chul‐Min Ahn
SJR Q1Scientific ReportsOA

Limited knowledge exists regarding the predictors of mortality after successful weaning of venoarterial extracorporeal membrane oxygenation (ECMO). We aimed to identify predictors of in-hospital mortality in patients with cardiogenic shock (CS) after successful weaning from ECMO. Data were obtained from a multicenter registry of CS. Successful ECMO weaning was defined as survival with minimal mean arterial pressure (> 65 mmHg) for > 24 h after ECMO removal. The primary outcome was in-hospital mo

Biomedical EngineeringEngineering
11
Article|9 citations·2016
Efficacy and safety of endovascular treatment for femoropopliteal lesions of TASC II type C and D compared with TASC II type A and B in Korea
Hyung Joon Joo, Duck Hyun Jang, Cheol Woong Yu, Young Jin Choi, Jinsik Park, Hyun‐Jong Lee, Jae Hyoung Park, Soon Jun Hong, Do‐Sun Lim
SJR Q2Vascular

Objective To compare the long-term safety and clinical efficacy of endovascular treatment for TASC-II type C/D femoropopliteal lesion compared with TASC-II type A/B femoropopliteal lesion in Korea. Methods A total of 179 limbs [TASC-II A/B femoropopliteal lesion (group I, n = 105 limbs) and TASC-II C/D (group II, n = 74 limbs)] were retrospectively analyzed from patients who underwent angioplasty with or without primary stent implantation between February 2008 and November 2012 at two medical ce

SurgeryMedicine
12
Article|8 citations·2020
Differential clinical impact of chronic total occlusion revascularization based on left ventricular systolic function
Hyungdon Kook, Jeong Hoon Yang, Jae Young Cho, Duck Hyun Jang, Min Sun Kim, Juneyoung Lee, Seung Hun Lee, Hyung Joon Joo, Jae Hyoung Park, Soon Jun Hong, Je Sang Kim, Hyun‐Jong Lee
SJR Q1Clinical Research in CardiologyOA

BACKGROUND: The effect of chronic total occlusion (CTO) revascularization on survival remains controversial. Furthermore, data regarding outcome differences for CTO revascularization based on left ventricular systolic function (LVSF) are limited. The differential outcomes from CTO revascularization in patients with preserved LVSF (PLVSF) versus reduced LVSF (RLVSF) were assessed. METHODS: A total of 2,173 CTO patients were divided into either a PLVSF (n = 1661, Ejection fraction ≥ 50%) or RLVSF

SurgeryMedicine
13
Article|6 citations·2013
Long-term effectiveness and safety of triple versus dual antiplatelet therapy after percutaneous coronary intervention for unprotected left main coronary artery disease
Hyun‐Jong Lee, Cheol Woong Yu, Heung Kon Hwang, Rak Kyeong Choi, Jin-Sik Park, Hu Li, Young Moo Ro
SJR Q3Coronary Artery Disease

TAPT after drug-eluting stent implantation in patients with uLMCAD did not improve the long-term clinical outcome when compared with conventional DAPT, although it was a safe strategy.

SurgeryMedicine
14
Article|6 citations·2014
Quadricuspid aortic valve stenosis which caused multi-organ failure and was treated by transcatheter aortic valve implantation after balloon aortovalvuloplasty as a bridge therapy
Cheol Woong Yu, Hyun‐Jong Lee
SJR Q1EuroIntervention
Cardiology and Cardiovascular MedicineMedicine
15
Article|5 citations·2019
Efficacy of postprocedural anticoagulation after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
Pil Sang Song, Min Jeong Kim, Ki‐Hyun Jeon, Sungmin Lim, Jin-Sik Park, Rak Kyeong Choi, Je Sang Kim, Hyun‐Jong Lee, Tae‐Hoon Kim, Young Jin Choi, Do‐Sun Lim, Cheol Woong Yu
SJR Q3MedicineOA

There exists controversy on whether and for how long anticoagulation is necessary after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI).We aimed to study the impact of prolonged (>24 h) or brief (<24 h) postprocedural anticoagulation on infarct size assessed by cardiac magnetic resonance (CMR) after 30 days as well as on left ventricular ejection fraction (LVEF) and left ventricular (LV) remodeling evaluated by 2D-echocardiography after 9 m

Cardiology and Cardiovascular MedicineMedicine

Research Areas

SurgeryCardiology and Cardiovascular MedicineBiomedical EngineeringPulmonary and Respiratory MedicineRadiology, Nuclear Medicine and ImagingMolecular Biology

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