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Dong Hwan Lee

Seoul National University · Computer Science

About the Lab

Professor Dong Hwan Lee's research lab specializes in catalysis, particularly in the development of transition metal-catalyzed C–H functionalization and cross-coupling reactions for sustainable organic synthesis. The lab also focuses on machine learning applications in neuroscience and mental health, using EEG and QEEG data to classify psychiatric disorders. Additionally, the lab investigates advanced materials for energy and electronics, including zeolite-supported catalysts and parameter estimation in NAND flash memory. The integration of chemistry, data science, and materials science defines the lab’s interdisciplinary approach.

catalysismachine learningEEG analysiszeolite catalystsmemory devices

Research Overview

Papers
210
Total Citations
2,256
Papers (5y)
53
Primary Field
Computer Science

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
53total
2021
2022
2023
2024
2025
Citations per year (5y)
286total
20212022202320242025

Selected Papers

15
1
Article|188 citations·2011
Selective Catalytic C–H Alkylation of Alkenes with Alcohols
Donghwan Lee, Ki‐Hyeok Kwon, Chae S. Yi
SJR Q1Science

Alkenes and alcohols are among the most abundant and commonly used organic feedstock in industrial processes. We report a selective catalytic alkylation reaction of alkenes with alcohols that forms a carbon-carbon bond between vinyl carbon-hydrogen (C-H) and carbon-hydroxy centers with the concomitant loss of water. The cationic ruthenium complex [(C(6)H(6))(PCy(3))(CO)RuH](+)BF(4)(-) (Cy, cyclohexyl) catalyzes the alkylation in solution within 2 to 8 hours at temperatures ranging from 75° to 11

Organic ChemistryChemistry
2
Article|141 citations·2018
Effects of Internet and Smartphone Addictions on Depression and Anxiety Based on Propensity Score Matching Analysis
Yeon-Jin Kim, Hye Min Jang, Youngjo Lee, Donghwan Lee, Dai‐Jin Kim
SJR Q2International Journal of Environmental Research and Public HealthOA

The associations of Internet addiction (IA) and smartphone addiction (SA) with mental health problems have been widely studied. We investigated the effects of IA and SA on depression and anxiety while adjusting for sociodemographic variables. In this study, 4854 participants completed a cross-sectional web-based survey including socio-demographic items, the Korean Scale for Internet Addiction, the Smartphone Addiction Proneness Scale, and the subscales of the Symptom Checklist 90 Items-Revised.

Sociology and Political ScienceSocial Sciences
3
Article|107 citations·2011
Sparse partial least-squares regression and its applications to high-throughput data analysis
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawitan
SJR Q2Chemometrics and Intelligent Laboratory Systems
Analytical ChemistryChemistry
4
Article|97 citations·2021
Identification of Major Psychiatric Disorders From Resting-State Electroencephalography Using a Machine Learning Approach
Su Mi Park, Boram Jeong, Da Young Oh, Chi-Hyun Choi, Hee Yeon Jung, Jun‐Young Lee, Donghwan Lee, Jung‐Seok Choi
SJR Q1Frontiers in PsychiatryOA

We aimed to develop a machine learning (ML) classifier to detect and compare major psychiatric disorders using electroencephalography (EEG). We retrospectively collected data from medical records, intelligence quotient (IQ) scores from psychological assessments, and quantitative EEG (QEEG) at resting-state assessments from 945 subjects [850 patients with major psychiatric disorders (six large-categorical and nine specific disorders) and 95 healthy controls (HCs)]. A combination of QEEG parameter

Cognitive NeuroscienceNeuroscience
5
Article|90 citations·2012
Estimation of NAND Flash Memory Threshold Voltage Distribution for Optimum Soft-Decision Error Correction
Donghwan Lee, Wonyong Sung
SJR Q1IEEE Transactions on Signal Processing

As the feature size of NAND flash memory decreases, the threshold voltage signal becomes less reliable, and its distribution varies significantly with the number of program-erase (PE) cycles and the data retention time. We have developed parameter estimation algorithms to find the means and variances of the threshold voltage distribution that is modeled as a Gaussian mixture. The proposed methods find the best-fit parameters by minimizing the squared Euclidean distance between the measured thres

Computer Networks and CommunicationsComputer Science
6
Article|87 citations·2009
Expanded Heterogeneous Suzuki–Miyaura Coupling Reactions of Aryl and Heteroaryl Chlorides under Mild Conditions
Donghwan Lee, Minkee Choi, Byung‐Woo Yu, Ryong Ryoo, Abu Taher, Shahin Hossain, Myung‐Jong Jin
SJR Q1Advanced Synthesis & Catalysis

Abstract A mesoporous LTA zeolite (MP‐LTA)‐supported palladium catalyst was developed for the highly efficient Suzuki–Miyaura reaction of aryl and heteroaryl chlorides. The couplings of various aryl chlorides with arylboronic acids in aqueous ethanol were efficiently achieved in the presence of 1.0 mol% of the catalyst. Furthermore, the scope of this catalyst was extended to the coupling of heteroaryl chlorides. Regardless of the substituents, all of the coupling reactions were very clean and hi

Organic ChemistryChemistry
7
Article|60 citations·2020
Associations of personality and clinical characteristics with excessive Internet and smartphone use in adolescents: A structural equation modeling approach
Boram Jeong, Ji Yoon Lee, Bo Mi Kim, Eunmin Park, Jun-Gun Kwon, Dai‐Jin Kim, Youngjo Lee, Jung‐Seok Choi, Donghwan Lee
SJR Q1Addictive Behaviors
Sociology and Political ScienceSocial Sciences
8
Article|49 citations·2010
Super-sparse principal component analyses for high-throughput genomic data
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawitan
SJR Q1BMC BioinformaticsOA

BACKGROUND: Principal component analysis (PCA) has gained popularity as a method for the analysis of high-dimensional genomic data. However, it is often difficult to interpret the results because the principal components are linear combinations of all variables, and the coefficients (loadings) are typically nonzero. These nonzero values also reflect poor estimation of the true vector loadings; for example, for gene expression data, biologically we expect only a portion of the genes to be express

Computational MathematicsMathematics
9
Article|48 citations·2010
General and highly active catalyst for mono and double Hiyama coupling reactions of unreactive aryl chlorides in water
Donghwan Lee, Ji‐Young Jung, Myung‐Jong Jin
SJR Q1Chemical Communications

Catalyst A was developed for highly efficient Hiyama couplings of less reactive (hetero)aryl chlorides in water. This catalyst also showed excellent reactivity for the one-pot double couplings of aryl dichlorides.

Organic ChemistryChemistry
10
Article|42 citations·2014
Hypertrophic Cardiomyopathy in Pompe Disease Is Not Limited to the Classic Infantile-Onset Phenotype
Donghwan Lee, Wenjuan Qiu, Jeongho Lee, Yin‐Hsiu Chien, Wuh‐Liang Hwu
SJR Q2JIMD ReportsOA
PhysiologyMedicine
11
Article|39 citations·2008
A highly effective azetidine–Pd(II) catalyst for Suzuki–Miyaura coupling reactions in water
Donghwan Lee, Young Hoon Lee, Dong Il Kim, Yang Kim, Woo Taik Lim, Jack M. Harrowfield, P. Thuéry, Myung‐Jong Jin, Yu Chul Park, Ik-Mo Lee
SJR Q3Tetrahedron
Organic ChemistryChemistry
12
Article|29 citations·2014
Decision Directed Estimation of Threshold Voltage Distribution in NAND Flash Memory
Donghwan Lee, Wonyong Sung
SJR Q1IEEE Transactions on Signal Processing

High-density NAND flash memory suffers from the data retention problem because even small charge leakage incurs a large threshold voltage shift as the transistor size shrinks. In this paper, we develop a decision directed estimation (DDE) algorithm to know the effects of charge leakage in NAND flash memory using the error pattern of the accessed data. While the conventional sensing directed estimation (SDE) method demands extra memory sensing to know the signal distribution, the proposed DDE alg

Computer Networks and CommunicationsComputer Science
13
Article|21 citations·2020
Investigation of Correlated Internet and Smartphone Addiction in Adolescents: Copula Regression Analysis
Minji Lee, Sun Ju Chung, Youngjo Lee, Sera Park, Jun-Gun Kwon, Dai‐Jin Kim, Donghwan Lee, Jung‐Seok Choi
SJR Q2International Journal of Environmental Research and Public HealthOA

Internet and smartphone addiction have become important social issues. Various studies have demonstrated their association with clinical and psychological factors, including depression, anxiety, aggression, anger expression, and behavioral inhibition, and behavioral activation systems. However, these two addictions are also highly correlated with each other, so the consideration of the relationship between internet and smartphone addiction can enhance the analysis. In this study, we considered t

Sociology and Political ScienceSocial Sciences
14
Article|21 citations·2022
Application of Machine Learning Classification to Improve the Performance of Vancomycin Therapeutic Drug Monitoring
Soo-Young Lee, Moonsik Song, Jongdae Han, Donghwan Lee, Bo‐Hyung Kim
SJR Q1PharmaceuticsOA

Bayesian therapeutic drug monitoring (TDM) software uses a reported pharmacokinetic (PK) model as prior information. Since its estimation is based on the Bayesian method, the estimation performance of TDM software can be improved using a PK model with characteristics similar to those of a patient. Therefore, we aimed to develop a classifier using machine learning (ML) to select a more suitable vancomycin PK model for TDM in a patient. In our study, nine vancomycin PK studies were selected, and a

PharmacologyMedicine
15
Article|17 citations·2022
Multiple-Kernel Support Vector Machine for Predicting Internet Gaming Disorder Using Multimodal Fusion of PET, EEG, and Clinical Features
Boram Jeong, Jiyoon Lee, Heejung Kim, Seungyeon Gwak, Yu Kyeong Kim, So Young Yoo, Donghwan Lee, Jung‐Seok Choi
SJR Q2Frontiers in NeuroscienceOA

Internet gaming disorder (IGD) has become an important social and psychiatric issue in recent years. To prevent IGD and provide the appropriate intervention, an accurate prediction method for identifying IGD is necessary. In this study, we investigated machine learning methods of multimodal neuroimaging data including Positron Emission Tomography (PET), Electroencephalography (EEG), and clinical features to enhance prediction accuracy. Unlike the conventional methods which usually concatenate al

Sociology and Political ScienceSocial Sciences

Research Areas

Computer Networks and CommunicationsStatistics and ProbabilityArtificial IntelligenceMolecular BiologyLiterature and Literary TheorySociology and Political Science

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