Dong Hyun Jang
Seoul National University · Medicine
About the Lab
Professor Dong Hyun Jang's research lab specializes in biomedical engineering and emergency medicine, focusing on innovative diagnostic technologies and clinical outcomes in critical care. The lab develops rapid, point-of-care diagnostic systems—such as microfluidic fluorescence in situ hybridization (μFISH) for early bacteremia detection—and investigates biomarkers like phosphate levels in sepsis to improve patient prognosis. It also explores clinical factors affecting outcomes in emergency settings, including cardiac arrest resuscitation duration and hospital-acquired pressure ulcers in emergency departments. The lab bridges engineering innovation with clinical urgency to enhance diagnosis, treatment, and patient survival in acute care environments.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15DRAMs in modules are preferably arranged in multiple ranks to increase system band-width. However, this limits the input/output (I/O) speed since increased channel loading causes degradation in signal integrity. To overcome the I/O speed limit, several buffered module solutions have been proposed, where data pins are buffered by additional chips. However, this increases power consumption and latency significantly. We present a 3D DRAM with TSVs that overcomes the limits of conventional module ap
BACKGROUND: A favorable neurological outcome is closely related to patient characteristics and total cardiopulmonary resuscitation (CPR) duration. The total CPR duration consists of pre-hospital and in-hospital durations. To date, consensus is lacking on the optimal total CPR duration. Therefore, this study aimed to determine the upper limit of total CPR duration, the optimal cut-off time at the pre-hospital level, and the time to switch from conventional CPR to alternative CPR such as extracorp
It is not easy to ensure optimal prevention of hospital-acquired pressure ulcer (HAPU) in crowded emergency departments (EDs). We hypothesised that a prolonged ED length of stay (LOS) is associated with an increased risk of HAPU. This is a single-centre observational study. Prospectively collected HAPU surveillance data were analysed. Adult (aged ≥20 years) patients admitted through the ED from April 1, 2013 to December 31, 2016 were included. The primary outcome was the development of HAPU with
BACKGROUND: Ischaemic tissue injury caused by tissue hypoperfusion is one of the major consequences of sepsis. Phosphate concentrations are elevated in ischaemic tissue injury. This study was performed to investigate the association of phosphate concentrations with mortality in patients with sepsis. METHODS: This was a retrospective cohort study of patients with sepsis conducted at an urban, tertiary care emergency department (ED) in Korea. Patients with sepsis arriving between March 2010 and Ap
The current diagnosis of bacteremia mainly relies on blood culture, which is inadequate for the rapid and quantitative determination of most bacteria in blood. Here, a quantitative, multiplex, microfluidic fluorescence in situ hybridization method (μFISH) is developed, which enables early and rapid (3-h) diagnosis of bacteremia without the need for prior blood culture. This novel technology employs mannose-binding lectin-coated magnetic nanoparticles, which effectively opsonize a broad range of
BACKGROUND: The selection of initial empirical antibiotics is an important issue in the treatment of severe community-acquired pneumonia (CAP). This study aimed to investigate whether empirical antibiotic prescription concordant with guidelines in the emergency department (ED) affects 30-day mortality in patients with severe CAP. METHODS: We conducted a retrospective analysis of adult patients with severe CAP who were hospitalized in the ED. Severe CAP was defined according to the criteria of th
Research Areas
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