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Dong Oh Kang

Korea University · Medicine

About the Lab

Professor Dong Oh Kang's research lab specializes in cardiovascular medicine with a focus on the intersection of metabolic health, neuro-cardiovascular interactions, and advanced diagnostic imaging. The lab investigates the prognostic implications of sarcopenia, body composition, and systemic inflammation in patients with coronary artery disease, acute myocardial infarction, and heart failure. Key research directions include the role of brain emotional processing (e.g., amygdalar activity) in plaque instability, the impact of lifestyle factors such as alcohol consumption on cardiovascular outcomes, and the use of non-invasive tools like bioelectrical impedance analysis and cardiopulmonary coupling for early detection of sleep-disordered breathing and fluid overload. The lab emphasizes translational research using multimodal imaging and biomarkers to improve risk stratification and personalized management in cardiovascular disease.

cardiovascular riskbody compositionneuro-cardiovascular axisbioelectrical impedancesleep-disordered breathing

Research Overview

Papers
194
Total Citations
909
Papers (5y)
128
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
128total
2021
2022
2023
2024
2025
Citations per year (5y)
326total
20212022202320242025

Selected Papers

15
1
Article|75 citations·2019
Prognostic Impact of Low Skeletal Muscle Mass on Major Adverse Cardiovascular Events in Coronary Artery Disease: A Propensity Score-Matched Analysis of a Single Center All-Comer Cohort
Dong Oh Kang, So Yeon Park, Byoung Geol Choi, Jin Oh Na, Cheol Ung Choi, Eung Ju Kim, Seung‐Woon Rha, Chang Gyu Park, Suk‐Joo Hong, Hong Seog Seo
SJR Q1Journal of Clinical MedicineOA

The impact of sarcopenia on atherosclerotic cardiovascular disease remains unclear. We aimed to investigate the prognostic impact of sarcopenia on coronary artery disease (CAD). A total of 475 patients with CAD who underwent successful percutaneous coronary intervention (PCI) and computed tomography (CT) were enrolled. The cross-sectional area of skeletal muscle at the first lumbar (L1) vertebral level was measured, and sex-specific cut-off values of L1 skeletal muscle index (L1 SMI; male <31

PhysiologyMedicine
2
Article|67 citations·2020
Stress-associated neurobiological activity is linked with acute plaque instability via enhanced macrophage activity: a prospective serial 18F-FDG-PET/CT imaging assessment
Dong Oh Kang, Jae Seon Eo, Eun‐Jin Park, Hyeong Soo Nam, Joon Woo Song, Ye Hee Park, So Yeon Park, Jin Oh Na, Cheol Ung Choi, Eung Ju Kim, Seung‐Woon Rha, Chang Gyu Park
SJR Q1European Heart Journal

AIMS: Emotional stress is associated with future cardiovascular events. However, the mechanistic linkage of brain emotional neural activity with acute plaque instability is not fully elucidated. We aimed to prospectively estimate the relationship between brain amygdalar activity (AmygA), arterial inflammation (AI), and macrophage haematopoiesis (HEMA) in acute myocardial infarction (AMI) as compared with controls. METHODS AND RESULTS: 18F-fluorodeoxyglucose positron emission tomography/computed

Cardiology and Cardiovascular MedicineMedicine
3
Article|40 citations·2020
Cardiovascular and Bleeding Risks Associated With Nonsteroidal Anti-Inflammatory Drugs After Myocardial Infarction
Dong Oh Kang, Hyonggin An, Geun U. Park, Yunjin Yum, Eun‐Jin Park, Yoonjee Park, Won Young Jang, Woohyeun Kim, Jah Yeon Choi, Seung‐Young Roh, Jin Oh Na, Jin Won Kim
SJR Q1Journal of the American College of Cardiology
PharmacologyMedicine
4
Article|26 citations·2019
Time-dependent prognostic effect of high sensitivity C-reactive protein with statin therapy in acute myocardial infarction
Dong Oh Kang, Yoonjee Park, Ji Hoon Seo, Myung Ho Jeong, Shung Chull Chae, Tae Hoon Ahn, Won Young Jang, Woohyeun Kim, Eun Jin Park, Byoung Geol Choi, Jin Oh Na, Cheol Ung Choi
SJR Q2Journal of CardiologyOA
SurgeryMedicine
5
Article|21 citations·2015
Triple antithrombotic therapy versus dual antiplatelet therapy in patients with atrial fibrillation undergoing drug-eluting stent implantation
Dong Oh Kang, Cheol Woong Yu, Hee Dong Kim, Jae Young Cho, Hyung Joon Joo, Rak Kyong Choi, Jin-Sik Park, Hyun‐Jong Lee, Je Sang Kim, Jae Hyung Park, Soon Jun Hong, Do‐Sun Lim
SJR Q3Coronary Artery Disease

In AF patients undergoing DES implantation, prolonged administration of TAT may be harmful due to the substantial increase in the risk for major bleeding without any reduction in MACCE.

Cardiology and Cardiovascular MedicineMedicine
6
Article|20 citations·2024
Reduced Alcohol Consumption and Major Adverse Cardiovascular Events Among Individuals With Previously High Alcohol Consumption
Dong Oh Kang, Dae In Lee, Seung‐Young Roh, Jin Oh Na, Cheol Ung Choi, Jin Won Kim, Eung Ju Kim, Seung‐Woon Rha, Chang Gyu Park, Ye-Seul Kim, Yonghwan Kim, Hyo‐Sun You
SJR Q1JAMA Network OpenOA

Importance: Cardiovascular benefits of mild to moderate alcohol consumption need to be validated in the context of behavioral changes. The benefits of reduced alcohol consumption among people who drink heavily across different subtypes of cardiovascular disease (CVD) are unclear. Objective: To investigate the association between reduced alcohol consumption and risk of major adverse cardiovascular events (MACEs) in individuals who drink heavily across different CVD subtypes. Design, Setting, and

Pathology and Forensic MedicineMedicine
7
Review|17 citations·2025
Exploring the complex interplay between alcohol consumption and cardiovascular health: Mechanisms, evidence, and future directions
Dae In Lee, Sunwon Kim, Dong Oh Kang
SJR Q1Trends in Cardiovascular Medicine
Pathology and Forensic MedicineMedicine
8
Article|13 citations·2020
Impact of Sleep-Disordered Breathing on Functional Outcomes in Ischemic Stroke
Dong Oh Kang, Chi Kyung Kim, Yoonjee Park, Won Young Jang, Woohyeun Kim, Jah Yeon Choi, Seung‐Young Roh, Cheol Ung Choi, Eung Ju Kim, Seung‐Woon Rha, Chang Gyu Park, Hong Seog Seo
SJR Q1Stroke

Background and Purpose: Cardiopulmonary coupling (CPC) analysis is an easily assessable method to evaluate sleep-disordered breathing (SDB); however, its prognostic impact in patients with acute ischemic stroke needs to be investigated. We performed a CPC analysis using Holter monitoring at the early stage of noncardioembolic ischemic stroke to investigate the prognostic effect of SDB on functional impairment at the 3-month follow-up. Methods: A total 615 patients with acute noncardioembolic isc

PhysiologyMedicine
9
Article|11 citations·2014
Absolute change in fasting plasma glucose over 12months is associated with 2-year and 5-year major adverse cardiovascular events in patients with drug-eluting stent implants
Dong Oh Kang, Hong Seog Seo, Byung Geol Choi, Eun‐Mi Lee, Ji Park Kim, Sun Ki Lee, Sung Il Im, Jin Oh Na, Cheol Ung Choi, Hong Euy Lim, Jin Won Kim, Eung Ju Kim
SJR Q1International Journal of Cardiology
SurgeryMedicine
10
Article|8 citations·2025
Phase angle in bioelectrical impedance analysis for assessing congestion in acute heart failure
Sangho Sohn, Jinsung Jeon, Ji Eun Lee, Soohyung Park, Dong Oh Kang, Eun Jin Park, Dae In Lee, Jah Yeon Choi, Seung Young Roh, Jin Oh Na, Cheol Ung Choi, Jin Won Kim
SJR Q1PLoS ONEOA

BACKGROUND: The phase angle (PhA) in bioelectrical impedance analysis (BIA) reflects the cell membrane integrity or body fluid equilibrium. We examined how the PhA aligns with previously known markers of acute heart failure (HF) and assessed its value as a screening tool. METHODS: PhA was measured in 50 patients with HF and 20 non-HF controls along with the edema index (EI), another BIA parameter suggestive of edema. Chest computed tomography-measured lung fluid content (LFC) was used to assess

PhysiologyMedicine
11
Article|6 citations·2023
Feasibility and safety of non-contrast optical coherence tomography imaging using hydroxyethyl starch in coronary arteries
Dong Oh Kang, Hyeong Soo Nam, Sunwon Kim, Hongki Yoo, Jin Won Kim
SJR Q1Scientific ReportsOA

Intracoronary optical coherence tomography (OCT) requires injection of flushing media for image acquisition. Alternative flushing media needs to be investigated to reduce the risk of contrast-induced renal dysfunction. We investigated the feasibility and safety of pentastarch (hydroxyethyl starch) for clinical OCT imaging. We prospectively enrolled 43 patients with 70 coronary lesions (46-stented; 24-native). Total 81 OCT pullback pairs were obtained by manual injection of iodine contrast, follo

SurgeryMedicine
12
Article|6 citations·2024
Long-term efficacy of drug-coated balloon-based treatment for de novo left anterior descending artery disease
Dong Oh Kang, Sunwon Kim, Bitna Kim, Ae‐Young Her, Eun‐Seok Shin
SJR Q1Scientific ReportsOA

Drug-coated balloons (DCB) are increasingly utilized in percutaneous coronary intervention (PCI), but their effectiveness in coronary artery disease (CAD) needs further exploration. This study investigates the efficacy and safety of a DCB-based strategy for de novo left anterior descending artery (LAD) disease. Patients with de novo LAD lesions treated with DCB alone or combined with drug-eluting stents (DES) and were retrospectively enrolled from 2010 to 2023 (n = 268). The comparator group con

SurgeryMedicine
13
Article|4 citations·2014
Endometrial Stromal Sarcoma Presented as an Incidental Lung Mass with Multiple Pulmonary Nodules
Dong Oh Kang, Sue In Choi, Jee Youn Oh, Jae Kyeom Sim, Jong Hyun Choi, Ji Yung Choo, Jin Wook Hwang, Seung Heon Lee, Jeong Hyeon Lee, Ki Yeol Lee, Chol Shin, Je Hyeong Kim
SJR Q2Tuberculosis & respiratory diseasesOA

Low-grade endometrial stromal sarcoma (ESS) is an uncommon gynecologic malignancy of mesodermal origin. Pulmonary metastasis of low-grade ESS can occur years and decades after the treatment of the primary disease. Low-grade ESS is frequently mistaken as benign uterine neoplasm like uterine leiomyoma, which can potentially lead to a misdiagnosis. We present a case of a 42-year-old woman with low-grade ESS, that initially presented as an incidental lung mass with multiple pulmonary nodules, seven

Obstetrics and GynecologyMedicine
14
Article|4 citations·2023
Quantitative Association between Computed-Tomography-Based L1 Skeletal Muscle Indices and Major Adverse Clinical Events Following Percutaneous Coronary Intervention
Eun Jin Park, So Yeon Park, Jaeho Kang, Wonsang Chu, Dong Oh Kang
SJR Q1Journal of Clinical MedicineOA

Sarcopenia is as a non-traditional risk factor for atherosclerotic cardiovascular disease. Further investigation is required to elucidate the prognostic significance of computed tomography (CT)-based sarcopenia assessment in coronary artery disease (CAD). We prospectively enrolled 475 patients, who underwent coronary stent implantation and peri-procedural CT scans within one month. Skeletal muscle index (SMI) was assessed cross-sectionally at the first lumbar vertebra (L1) level. The participant

PhysiologyMedicine
15
Article|4 citations·2008
Successful endoscopic treatment of biliary stricture following mesenteric tear caused by blunt abdominal trauma
Dong Oh Kang, Tae Hyo Kim, Seung Suk You, Hyun Ju Min, Hyun Jin Kim, Woon Tae Jung, Ok‐Jae Lee
SJR Q1World Journal of GastroenterologyOA

Biliary duct injuries are frequently iatrogenic, being associated with surgery for gallbladder stones. However, blunt abdominal trauma such as a motor vehicle crash is a rare cause of extrahepatic biliary stricture. A few reports have been published on biliary strictures treated with endoscopic therapy. In the present study, we describe a suprapancreatic biliary stricture associated with mesenteric tear following road traffic accident. We performed endoscopic stent placement, which was successfu

SurgeryMedicine

Research Areas

SurgeryCardiology and Cardiovascular MedicineRadiology, Nuclear Medicine and ImagingPhysiologyComplementary and alternative medicineImmunology

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