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Dong Seok Lee

Seoul National University · Medicine

About the Lab

Professor Dong Seok Lee's research lab focuses on clinical and translational studies in internal medicine, with a strong emphasis on metabolic disorders, gastrointestinal diseases, and oncology. The lab investigates the complex interplay between body composition parameters—such as obesity, visceral adiposity, and sarcopenia—and metabolic syndrome, as well as the pathogenesis and management of rare and severe complications in cancer and inflammatory conditions. Research also extends to biomarker discovery (e.g., CCL28 in ulcerative colitis) and innovative diagnostic and therapeutic approaches for rare gastrointestinal malignancies and complications like disseminated intravascular coagulation in gastric cancer. The lab integrates clinical data with advanced diagnostic techniques to improve patient outcomes.

metabolic syndromegastrointestinal oncologybody compositionclinical biomarkersrare complications

Research Overview

Papers
44
Total Citations
302
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2022
2023
2024
2025
2026
Citations per year (5y)
79total
20222023202420252026

Selected Papers

15
1
Article|32 citations·2022
Adverse events following COVID-19 vaccination in South Korea between February 28 and August 21, 2021: A nationwide observational study
Dong Seok Lee, Ji Won Kim, Kook Lae Lee, Yong Jin Jung, Hyoun Woo Kang
SJR Q1International Journal of Infectious DiseasesOA

Although there were differences in the frequency of occurrence, various adverse reactions were confirmed in using all 4 COVID-19 vaccines, even with the BNT162b2 (Pfizer-BioNTech) vaccine. Caution is needed, and further research should be continuously conducted.

Infectious DiseasesMedicine
2
Article|29 citations·2021
Association of obesity, visceral adiposity, and sarcopenia with an increased risk of metabolic syndrome: A retrospective study
Su Hwan Kim, Hyoun Woo Kang, Ji Bong Jeong, Dong Seok Lee, Dong‐Won Ahn, Ji Won Kim, Byeong Gwan Kim, Kook Lae Lee, Sohee Oh, Soon Ho Yoon, Sang Joon Park
SJR Q1PLoS ONEOA

AIMS: Metabolic syndrome (MS) is a global health problem associated with an increased risk of diabetes mellitus (DM), cardiovascular disease (CVD), and cancer. Body composition parameters, including obesity, visceral adiposity, and sarcopenia contribute to the development of MS and CVD. Previous studies have investigated the association of individual body composition parameters with MS. Studies analyzing the association between multiple body composition parameters and MS have been rare. We aimed

PhysiologyMedicine
3
Article|15 citations·2022
Significance of digestive symptoms after COVID-19 vaccination: A retrospective single-center study
Dong Seok Lee, Ji Won Kim, Kook Lae Lee, Yong Jin Jung, Hyoun Woo Kang
SJR Q1The American Journal of Emergency MedicineOA
Infectious DiseasesMedicine
4
Article|15 citations·2020
Expression of Chemokine CCL28 in Ulcerative Colitis Patients
Dong Seok Lee, Kook Lae Lee, Ji Bong Jeong, Sue Shin, Su Hwan Kim, Ji Won Kim
SJR Q1Gut and LiverOA

CCL28 could be useful for diagnosing UC. However, further validations of CCL28 on disease activity and severity are needed.

OncologyMedicine
5
Review|13 citations·2015
Primary esophageal mucosa-associated lymphoid tissue lymphoma diagnosed by using stacked forceps biopsy
Dong Seok Lee, Yongchel Ahn, Dae‐Woon Eom, Su Jin Lee
SJR Q1Diseases of the EsophagusOA

Non-Hodgkin lymphoma involving the esophagus is very rare. Only a few cases have been reported in the English literature to date, and it accounts for less than 1% of all cases of gastrointestinal lymphoma. As this malignancy manifests as a submucosal tumor, pathological diagnosis by using a simple endoscopic biopsy alone is difficult. Therefore, surgical biopsy, endoscopic mucosal resection, and endoscopic ultrasound-guided fine-needle aspiration have been used in most cases. Herein, we report a

GastroenterologyMedicine
6
Article|9 citations·2013
Advanced Gastric Cancer Associated with Disseminated Intravascular Coagulation Successfully Treated with 5-fluorouracil and Oxaliplatin
Dong Seok Lee, Seung‐Jin Yoo, Ho Suk Oh, Eun‐Jung Kim, Kwang Hoon Oh, Sang Jin Lee, Jong Kyu Park, Yongchel Ahn, Dae‐Woon Eom, Heui June Ahn
SJR Q1Journal of the Korean Gastric Cancer AssociationOA

Gastric cancer patients with acute disseminated intravascular coagulation experiences a rare but severe complication resulting in a dismal prognosis. We report a case of advanced gastric cancer complicated with disseminated intravascular coagulation with intractable tumor bleeding which was successfully treated with chemotherapy consisting of 5-fluorouracil and oxaliplatin. The patient was a 63-year-old man who complained of abdominal pain, melena, and dyspnea on 24 November 2010. We diagnosed s

Pulmonary and Respiratory MedicineMedicine
7
Article|8 citations·2014
Severe Gastroparesis following Radiofrequency Catheter Ablation for Atrial Fibrillation: Suggestion for Diagnosis, Treatment, and Device for Gastroparesis after RFCA
Dong Seok Lee, Sang Jin Lee
Case Reports in Gastrointestinal MedicineOA

Gastroparesis following radiofrequency catheter ablation (RFCA) is a very rare complication, as only two cases have been reported in the English literature. A 42-year-old man underwent RFCA due to recurrent drug-resistant symptomatic atrial fibrillation. The patient complained of indigestion and early satiety 2 days after the procedure. Contrast-enhanced computed tomography and an upper gastrointestinal series of the abdomen showed a large amount of material remaining in the stomach area. All fo

Cardiology and Cardiovascular MedicineMedicine
8
Article|7 citations·2020
Clinical significance of regional lymph node enlargement in patients with EGC within the expanded criteria for ESD
Dong Seok Lee, Jong Kyu Park, Sang Jin Lee, Gab Jin Cheon
SJR Q2BMC GastroenterologyOA

BACKGROUND: Lymph node (LN) metastasis is negligible in early gastric cancer (EGC) within expanded criteria for endoscopic submucosal dissection (ESD). However, regional lymph nodes in abdominal CT scans are sometimes enlarged in patients with EGC within the expanded criteria for endoscopic submucosal dissection (ESD). In this study, we investigated the clinical significance of regional lymph node enlargement on abdominal CT scan in patients with EGC within the expanded criteria for ESD. METHODS

Pulmonary and Respiratory MedicineMedicine
9
Article|6 citations·2023
Usefulness of a new polyvinyl alcohol hydrogel (PVA-H)-based simulator for endoscopic submucosal dissection training: a pilot study
Dong Seok Lee, Gin Hyug Lee, Sang Gyun Kim, Kook Lae Lee, Ji Won Kim, Ji Bong Jeong, Yong Jin Jung, Hyoun Woo Kang
SJR Q2Clinical EndoscopyOA

BACKGROUND/AIMS: We developed a new endoscopic submucosal dissection (ESD) simulator and evaluated its efficacy and realism for use training endoscopists. METHODS: An ESD simulator was constructed using polyvinyl alcohol hydrogel sheets and compared to a previous ESD simulator. Between March 1, 2020, and December 30, 2021, eight expert endoscopists from three different centers analyzed the procedure-related factors of the simulator. Five trainees performed gastric ESD exercises under the guidanc

Pulmonary and Respiratory MedicineMedicine
10
Article|5 citations·2019
A Newly Designed 3-Dimensional Printer-Based Gastric Hemostasis Simulator with Two Modules for Endoscopic Trainees (with Video)
Dong Seok Lee, Ji Yong Ahn, Gin Hyug Lee
SJR Q1Gut and LiverOA

Background/Aims: We used 3-dimensional (3D) printing technology to create a new hemostasis simulator for the stomach and investigated its efficacy and realism in endoscopic hemostasis training. Methods: A new stomach hemostasis simulator, with two hemostasis modules for hemoclipping and injection, was constructed using a 3D printer. Twenty-one endoscopists, including 11 first-year fellows (beginner group) and 10 faculty members (expert group), tested the performance of the simulator. We recorded

GastroenterologyMedicine
11
Article|3 citations·2018
Technical Feasibility of a Guidetube for Various Endoscopic Procedures in Human Gastrointestinal Simulators
Dong Seok Lee, Byeong Gwan Kim, Kook Lae Lee, Yong Jin Jung, Ji Won Kim
SJR Q2Clinical EndoscopyOA

This preliminary study shows that guidetube-assisted endoscopic procedures are faster, easier, safer and cheaper than conventional endoscopic procedures.

SurgeryMedicine
12
Article|3 citations·2014
A Case of PICOLIGHT Powder Induced Thermal Injury of the Gastric Mucosa
Dong Seok Lee, Hyeon Seok Kim, Seung Hwan Lee, Joon Ho Jeon, Yong Kyu Lee
The Korean Journal of Helicobacter and Upper Gastrointestinal ResearchOA

There are many reports about causes of corrosive agents such as acids and alkaline and occasionally hot food in either liquid or solid forms as causes of upper gastrointestinal mucosal injury. However, there have been no reports on bowel preparation solutions as a cause of upper gastrointestinal injury. We describe a case of bowel preparation solution (PICOLIGHT powder) induced thermal injury of the gastric mucosa with a review of the literature. (

Pulmonary and Respiratory MedicineMedicine
13
Article|2 citations·2020
Technical feasibility of a newly designed bendable forceps for difficult endoscopic tissue samplings (with video)
Dong Seok Lee, Ji Won Kim, Kook Lae Lee, Byeong Gwan Kim, Su Hwan Kim, Jeong‐Sik Byeon
SJR Q1Surgical Endoscopy
SurgeryMedicine
14
Article|2 citations·2020
Analysis of droplets generated during gastrointestinal endoscopic examinations using a high speed camera
Dong Seok Lee, Ji Won Kim
SJR Q1EndoscopyOA

Droplets released from the mouth of a COVID-19 infected patient are an important source of infection [1]. Currently, gastrointestinal (GI) endoscopy preventative guidelines have been developed based on cough models with droplet travel distances of over 2 m [2] [3] [4] [5] [6]. However, the droplet-related studies reported so far have mostly focused on cough models related to respiratory disease. Thus far, no studies have been conducted on droplets generated during GI endoscopic examinations.

Pulmonary and Respiratory MedicineMedicine
15
Article|2 citations·2024
Efficacy of colonoscopic re-examination across the entire colon: a randomized controlled trial
Dong Seok Lee, Jeong‐Seon Ji, Tae‐Geun Gweon, Myeongsook Seo, Hwang Choi
SJR Q1Surgical Endoscopy
OncologyMedicine

Research Areas

Pulmonary and Respiratory MedicineSurgeryCardiology and Cardiovascular MedicineOncologyInfectious DiseasesRadiology, Nuclear Medicine and Imaging

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