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Donggeun Lee

Seoul National University · Materials Science

About the Lab

Professor Donggeun Lee's research lab focuses on plant stress biology and regenerative medicine, with a central emphasis on understanding molecular mechanisms underlying root development and drought tolerance in crops. The lab investigates transcriptional regulators such as OsERF71 and OsNAC6 to decipher how plants reprogram root architecture under abiotic stress, aiming to enhance crop resilience through biotechnological applications. In parallel, the lab pioneers the clinical translation of nanomaterials, notably detonation nanodiamonds (NDs), by integrating them into biomaterials like ND-embedded gutta percha for improved root canal therapy. This interdisciplinary approach bridges plant developmental biology and nanomedicine to address global challenges in agriculture and dentistry.

drought toleranceroot developmentnanodiamondstranscription factorsregenerative medicine

Research Overview

Papers
369
Total Citations
5,804
Papers (5y)
60
Primary Field
Materials Science

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
60total
2022
2023
2024
2025
2026
Citations per year (5y)
44total
20222023202420252026

Selected Papers

15
1
Article|239 citations·2016
Overexpression of the OsERF71 Transcription Factor Alters Rice Root Structure and Drought Resistance
Dong-Keun Lee, Harin Jung, Geupil Jang, Jin Seo Jeong, Youn Shic Kim, Sun‐Hwa Ha, Yang Do Choi, Ju‐Kon Kim
SJR Q1PLANT PHYSIOLOGYOA

Plant responses to drought stress require the regulation of transcriptional networks via drought-responsive transcription factors, which mediate a range of morphological and physiological changes. AP2/ERF transcription factors are known to act as key regulators of drought resistance transcriptional networks; however, little is known about the associated molecular mechanisms that give rise to specific morphological and physiological adaptations. In this study, we functionally characterized the ri

Plant ScienceAgricultural and Biological Sciences
2
Article|188 citations·2003
Expression of an Expansin Gene Is Correlated with Root Elongation in Soybean
Dong-Keun Lee, Ji Hoon Ahn, Sang-Kee Song, Yang Do Choi, Jong Seob Lee
SJR Q1PLANT PHYSIOLOGYOA

Expansin is a family of proteins that catalyze long-term expansion of cell walls and has been considered a principal protein that affects cell expansion in plants. We have identified the first root-specific expansin gene in soybean (Glycine max), GmEXP1, which may be responsible for root elongation. Expression levels of GmEXP1 were very high in the roots of 1- to 5-d-old seedlings, in which rapid root elongation takes place. Furthermore, GmEXP1 mRNA was most abundant in the root tip region, wher

Plant ScienceAgricultural and Biological Sciences
3
Article|186 citations·2016
The rice OsNAC6 transcription factor orchestrates multiple molecular mechanisms involving root structural adaptions and nicotianamine biosynthesis for drought tolerance
Dong‐Keun Lee, Pil Joong Chung, Jin Seo Jeong, Geupil Jang, Seung Woon Bang, Harin Jung, Youn Shic Kim, Sun‐Hwa Ha, Yang Do Choi, Ju‐Kon Kim
SJR Q1Plant Biotechnology JournalOA

Drought has a serious impact on agriculture worldwide. A plant's ability to adapt to rhizosphere drought stress requires reprogramming of root growth and development. Although physiological studies have documented the root adaption for tolerance to the drought stress, underlying molecular mechanisms is still incomplete, which is essential for crop engineering. Here, we identified OsNAC6-mediated root structural adaptations, including increased root number and root diameter, which enhanced drough

Plant ScienceAgricultural and Biological Sciences
4
Article|170 citations·2015
Nanodiamond–Gutta Percha Composite Biomaterials for Root Canal Therapy
Dong-Keun Lee, Sue Vin Kim, Adelheid Nerisa Limansubroto, Albert Yen, Akrivoula Soundia, Cun‐Yu Wang, Wenyuan Shi, Christine Hong, Sotirios Tetradis, Yong Kim, No‐Hee Park, Mo Kang
SJR Q1ACS NanoOA

Root canal therapy (RCT) represents a standard of treatment that addresses infected pulp tissue in teeth and protects against future infection. RCT involves removing dental pulp comprising blood vessels and nerve tissue, decontaminating residually infected tissue through biomechanical instrumentation, and root canal obturation using a filler material to replace the space that was previously composed of dental pulp. Gutta percha (GP) is typically used as the filler material, as it is malleable, i

Materials ChemistryMaterials Science
5
Article|165 citations·2009
LATERAL ORGAN FUSION1andLATERAL ORGAN FUSION2function in lateral organ separation and axillary meristem formation inArabidopsis
Dong-Keun Lee, Matt Geisler, Patricia S. Springer
SJR Q1Development

Plant organs are generated from meristems throughout development. Patterning and elaboration of organ primordia occur as a result of organized cell division and expansion, processes that are likely to be controlled, in part, by meristem-derived signals. Communication between the meristem and lateral organs is crucial for meristem maintenance and organ patterning, and organ boundaries are thought to be important for mediating this communication. Arabidopsis thaliana LATERAL ORGAN FUSION1 (LOF1) e

Plant ScienceAgricultural and Biological Sciences
6
Article|149 citations·2015
The NF-YA transcription factor OsNF-YA7 confers drought stress tolerance of rice in an abscisic acid independent manner
Dong-Keun Lee, Hyung‐Il Kim, Geupil Jang, Pil Joong Chung, Jin Seo Jeong, Youn Shic Kim, Seung Woon Bang, Harin Jung, Yang Do Choi, Ju‐Kon Kim
SJR Q1Plant Science
Plant ScienceAgricultural and Biological Sciences
7
Article|112 citations·2004
Preparation of TiO2-coated hollow glass beads and their application to the control of algal growth in eutrophic water
Sung‐Chul Kim, Dong-Keun Lee
SJR Q1Microchemical Journal
Renewable Energy, Sustainability and the EnvironmentEnergy
8
Article|102 citations·2004
Photocatalytic oxidation of microcystin-LR in a fluidized bed reactor having TiO2-coated activated carbon
Dong-Keun Lee, Sung‐Chul Kim, Incheol Cho, Seong-Ji Kim, Sung Woo Kim
SJR Q1Separation and Purification Technology
Environmental ChemistryEnvironmental Science
9
Article|71 citations·2017
Clinical validation of a nanodiamond-embedded thermoplastic biomaterial
Dong-Keun Lee, Theodore Kee, Zhangrui Liang, Desiree Hsiou, Darron Miya, Brian Wu, Eiji O̅sawa, Edward Kai‐Hua Chow, Eric Sung, Mo Kang, Dean Ho
SJR Q1Proceedings of the National Academy of Sciences

Detonation nanodiamonds (NDs) are promising drug delivery and imaging agents due to their uniquely faceted surfaces with diverse chemical groups, electrostatic properties, and biocompatibility. Based on the potential to harness ND properties to clinically address a broad range of disease indications, this work reports the in-human administration of NDs through the development of ND-embedded gutta percha (NDGP), a thermoplastic biomaterial that addresses reinfection and bone loss following root c

Materials ChemistryMaterials Science
10
Article|66 citations·2016
Rice OsERF71-mediated root modification affects shoot drought tolerance
Dong-Keun Lee, Su-In Yoon, Youn Shic Kim, Ju‐Kon Kim
SJR Q1Plant Signaling & BehaviorOA

Drought is the most serious problem that impedes crop development and productivity worldwide. Although several studies have documented the root architecture adaption for drought tolerance, little is known about the underlying molecular mechanisms. Our latest study demonstrated that overexpression of the OsERF71 in rice roots under drought conditions modifies root structure including larger aerenchyma and radial root growth, and thereby, protects the rice plants from drought stresses. The OsERF71

Plant ScienceAgricultural and Biological Sciences
11
Article|61 citations·1988
Effect of Carbon Deposits on Carbon Monoxide Hydrogenation over Alumina-Supported Cobalt Catalyst
Dong-Keun Lee, Jin-Ho Lee, Son‐Ki Ihm
Applied Catalysis
Mechanical EngineeringEngineering
12
Article|59 citations·2004
Preparation of Al–Cu pillared clay catalysts for the catalytic wet oxidation of reactive dyes
Sung‐Chul Kim, Dong-Keun Lee
SJR Q1Catalysis Today
Materials ChemistryMaterials Science
13
Article|56 citations·2001
Selective formation of formaldehyde from carbon dioxide and hydrogen over PtCu/SiO2
Dong-Keun Lee, Dul-Sun Kim, Sung Woo Kim
SJR Q2Applied Organometallic Chemistry

CO2 hydrogenation was carried out at 423 K and 600 KPa with PtCu/SiO2 catalyst. Formaldehyde rather than methanol was mainly produced, and platinum is believed to play an important role in the selective production of formaldehyde from CO2 hydrogenation. The optimum atomic ratio of Pt/Cu in the PtCu/SiO2 catalyst for the selective production of formaldehyde was 0.03. Copyright © 2001 John Wiley & Sons, Ltd.

CatalysisChemical Engineering
14
Article|55 citations·2000
Catalytic wet air oxidation of carboxylic acids at atmospheric pressure
Dong-Keun Lee, Dul-Sun Kim
SJR Q1Catalysis Today
Atmospheric ScienceEarth and Planetary Sciences
15
Article|53 citations·2004
Photocatalytic oxidation of microcystin-LR with TiO2-coated activated carbon
Dong-Keun Lee, Sung‐Chul Kim, Seong-Ji Kim, Ik-Sang Chung, Sung Woo Kim
SJR Q1Chemical Engineering Journal
Environmental ChemistryEnvironmental Science

Research Areas

Materials ChemistryPlant ScienceMolecular BiologyMechanical EngineeringBiomedical EngineeringCivil and Structural Engineering

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