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Eul‐Sik Yoon

Korea University · Medicine

About the Lab

Professor Eul-Sik Yoon's research lab specializes in regenerative medicine and tissue engineering, with a focus on stem cell therapy and biomaterials for bone and soft tissue regeneration. The lab investigates the therapeutic potential of adipose-derived stem cells (ADSCs) and stromal vascular fraction (SVF) in critical-sized bone defects, utilizing biodegradable scaffolds such as PLGA and demineralized bone matrix. Additionally, the lab explores advanced imaging techniques—particularly high-resolution ultrasonography—for diagnosing and monitoring peripheral nerve disorders like carpal tunnel syndrome, and applies these insights to improve surgical outcomes. The integration of cell-based therapies with innovative biomaterials and clinical imaging underscores the lab’s translational approach to aesthetic and reconstructive surgery.

tissue engineeringadipose-derived stem cellsbone regenerationultrasonographyaesthetic surgery

Research Overview

Papers
214
Total Citations
2,707
Papers (5y)
23
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
23total
2022
2023
2024
2025
2026
Citations per year (5y)
91total
20222023202420252026

Selected Papers

15
1
Article|266 citations·2007
In Vivo Osteogenic Potential of Human Adipose-Derived Stem Cells/Poly Lactide-Co-Glycolic Acid Constructs for Bone Regeneration in a Rat Critical-Sized Calvarial Defect Model
Eul‐Sik Yoon, Sandipan Dhar, Daniel Chun, Nareg A. Gharibjanian, Gregory R. D. Evans
Tissue Engineering

Recent studies suggest that human adipose tissue contains pluripotent stem cells, which are similar to bone marrow-derived stem cells. The objective of the present study was to assess the effect in bone regenerating capability of human adipose-derived stem cells (ADSCs) cultured in osteogenic media layered over poly lactide-co-glycolic acid (PLGA) and implanted in a critical nude rat calvarial defect. Twenty-seven nude rats were randomized into 3 groups (n = 9): 1) PLGA alone (control), 2) PLGA

GeneticsMedicine
2
Article|94 citations·2004
Correlation of High-Resolution Ultrasonographic Findings With the Clinical Symptoms and Electrodiagnostic Data in Carpal Tunnel Syndrome
Chi‐Ho Lee, Taek Kun Kim, Eul Sik Yoon, Eun‐Sang Dhong
SJR Q2Annals of Plastic Surgery

There are several different imaging methods that are helpful in the diagnosis of carpal tunnel syndrome, including traditional radiography, computed tomography (CT), and magnetic resonance imaging (MRI). CT and MRI offer the advantage of providing direct visualization of the structural abnormality of the carpal tunnel and median nerve, but both of these modalities are expensive and time-consuming. Recently, high-resolution ultrasonography has been reported to be effective in the study of the mus

Radiology, Nuclear Medicine and ImagingMedicine
3
Article|69 citations·2015
A novel technique for robot assisted latissimus dorsi flap harvest
Jae-Hyun Chung, Hi‐Jin You, Hyonsurk Kim, Byung Il Lee, Seung Ha Park, Eul‐Sik Yoon
SJR Q1Journal of Plastic Reconstructive & Aesthetic Surgery
SurgeryMedicine
4
Article|65 citations·2005
Postoperative Morphologic Analysis of Carpal Tunnel Syndrome Using High-Resolution Ultrasonography
Chi‐Ho Lee, Taek Kun Kim, Eul Sik Yoon, Eun‐Sang Dhong
SJR Q2Annals of Plastic Surgery

The authors evaluated the morphologic changes that follow division of the transverse carpal ligament in patients with carpal tunnel syndrome (CTS) using high-resolution ultrasonography. Ten patients, for a total of 20 hands, underwent high-resolution ultrasonographic studies before the operation and 8 months after the operation. They were all diagnosed with bilateral idiopathic CTS. The authors evaluated the configuration of the median nerve and carpal tunnel at 3 different levels of the wrist:

Radiology, Nuclear Medicine and ImagingMedicine
5
Article|54 citations·2010
In Vivo Evaluation of Mixtures of Uncultured Freshly Isolated Adipose-Derived Stem Cells and Demineralized Bone Matrix for Bone Regeneration in a Rat Critically Sized Calvarial Defect Model
Seung Chul Rhee, Yi-Hwa Ji, Nareg A. Gharibjanian, Eun‐Sang Dhong, Seung Ha Park, Eul‐Sik Yoon
SJR Q2Stem Cells and Development

Although many studies have suggested that human adipose tissue contains pluripotent stem cells, a few reports are available on stromal vascular fraction (SVF). In the present study, we evaluated the bone formation capacities of SVF. We implanted uncultured freshly isolated adipose-derived stem cells combined with demineralized bone matrix (DBM) to induce bone regeneration in a critically sized rat calvarial defect model. We used DBM (DBX(®)) and/or poly(70L-lactide-co-30DL-lactide) copolymer PLA

GeneticsMedicine
6
Article|50 citations·2003
Advantages of the Presence of Living Dermal Fibroblasts Within Restylane for Soft Tissue Augmentation
Eul‐Sik Yoon, Seung‐Kyu Han, Woo Kyung Kim
SJR Q2Annals of Plastic Surgery

For the elimination of facial wrinkles and skin contour defects, injectable filler substances composed of commercially prepared nonanimal stabilized hyaluronic acid (Restylane) are now widely used. Although this method of suspension has been shown to be relatively safe and convenient, varying degrees of resorption have required repeated percutaneous injections. This study was undertaken to evaluate the feasibility of Restylane, which is a modified hyaluronic acid, combined with cultured human de

DermatologyMedicine
7
Article|44 citations·2006
Analysis of Incidences and Types of Complications in Mandibular Angle Ostectomy in Koreans
Eul‐Sik Yoon, Yeui-Seok Seo, Dong Hee Kang, Sang-Hwan Koo, Seung Ha Park
SJR Q2Annals of Plastic Surgery

A prominent mandibular angle is considered to be unattractive in Asians because it gives the face a square, coarse, and muscular appearance. Asian women desire to have an ovoid, reduced, and slender face by aesthetic mandibular angle resection. Mandibular angle ostectomy has been known to be effective and to satisfy both surgeons and patients. Especially in Korea, it has become as popular as facial bone contouring surgery, which reduces lower facial width. However, a narrow surgical field hinder

OrthodonticsDentistry
8
Article|41 citations·2020
Clinical Experience with Treatment of Aquafilling Filler-Associated Complications: A Retrospective Study of 146 Cases
Sik Namgoong, Hong Kyu Kim, Yong-Jae Hwang, Seung Ho Shin, Hi‐Jin You, Deok‐Woo Kim, Aeree Kim, Seung Pil Jung, Eul‐Sik Yoon
SJR Q1Aesthetic Plastic Surgery
DermatologyMedicine
9
Article|29 citations·2015
Clinical and radiological outcomes of transoral endoscope-assisted treatment of mandibular condylar fractures
Hi‐Jin You, Kyung‐Chul Moon, Eul‐Sik Yoon, B.-I. Lee, S.-H. Park
SJR Q1International Journal of Oral and Maxillofacial Surgery
SurgeryMedicine
10
Article|24 citations·2001
Failure of carbon dioxide laser treatment in three patients with penoscrotal extramammary Paget's disease
Jong Bo Choi, Eul‐Sik Yoon, D.K. Yoon, D.S. Kim, J.J. Kim, J.H. Cho
SJR Q1British Journal of Urology
DermatologyMedicine
11
Article|18 citations·2023
Assessing the preventive effect of immediate lymphatic reconstruction on the upper extremity lymphedema
Jae‐Ho Chung, Sang‐Ho Kwon, Seung Pil Jung, Seung Ha Park, Eul‐Sik Yoon
SJR Q2Gland SurgeryOA

Our results suggested that ILR may be a promising surgical treatment to prevent postoperative lymphedema. There is a need for larger studies with longer follow-up to confirm the findings obtained in our study.

OncologyMedicine
12
Article|17 citations·2007
An Anatomic Study and Clinical Application of Medial Pedis Flap in Asians
Eul‐Sik Yoon, Deok‐Woo Kim, Daniel Chun, Eun‐Sang Dhong, Sang-Hwan Koo, Seung Ha Park, Woo Kyung Kim
SJR Q2Annals of Plastic Surgery

Several investigators have reported their clinical experience with medial pedis flaps for reconstruction of soft tissue defects of the hand and digits. In a cadaveric study in 1997, Jayme and Hamilton described the anatomy of the medial branch of the deep division of the medial plantar artery, which is used in the medial pedis flap. However, they had only a few cases where this flap was used. There have been no such anatomic studies in Korea to date. We found the medial pedis flap to be a reliab

SurgeryMedicine
13
Article|16 citations·2021
Preliminary outcomes of combined surgical approach for lower extremity lymphedema: supraclavicular lymph node transfer and lymphaticovenular anastomosis
Jae‐Ho Chung, Yong-Jae Hwang, Seung Ha Park, Eul‐Sik Yoon
SJR Q2Journal of Plastic Surgery and Hand SurgeryOA

The combined approach showed a significant decrease in the circumference of LEL. Additional LVAs could reinforce the effect of a VLNT. Larger series with longer follow-up is needed to confirm our findings.

OncologyMedicine
14
Article|16 citations·2020
Robotic-assisted latissimus dorsi muscle flap for autologous chest reconstruction in poland syndrome
Kyung‐Chul Moon, Hyun-Dong Yeo, Eul‐Sik Yoon, B.I. Lee, S.H. Park, Jae‐Ho Chung, H.C. Lee
SJR Q1Journal of Plastic Reconstructive & Aesthetic Surgery
SurgeryMedicine
15
Article|16 citations·1999
Report of Phenol Peel for Asians
Eul Sik Yoon, Duck Sun Ahn
SJR Q1Plastic & Reconstructive Surgery

With the advancement of trichloroacetic acid peel technology and wound care, trichloroacetic acid peeling has become very successful in Korea. Its success has opened studies on the possibility of using phenol on Korean skin. Dr. Mee's phenol formula (molding mask technique) was chosen for experiments on Korean skin because of the presumed safety of use on non-Caucasian skin. Between January of 1996 and January of 1998, 30 cases of significant small pox scars were treated with phenol at the Korea

DermatologyMedicine

Research Areas

SurgeryDermatologyGeneticsOncologyRadiology, Nuclear Medicine and ImagingNeurology

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