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Eun-Kyung Bang

Ewha Womans University · Biochemistry, Genetics and Molecular Biology

About the Lab

Professor Eun-Kyung Bang's research lab specializes in oral and maxillofacial regenerative medicine, with a primary focus on bone regeneration and implant dentistry. The lab investigates the efficacy of various bone graft materials—such as freeze-dried human bone, bovine bone, hydroxyapatite, and synthetic carriers—combined with recombinant human bone morphogenetic protein-2 (rhBMP-2) for enhancing bone formation in craniofacial defects and sinus augmentation. Key research directions include guided bone regeneration (GBR), long-term implant survival, and the clinical and biological factors influencing peri-implant health, including peri-implantitis. The lab also explores preventive oral health interventions, particularly through education and visual tools like disclosing solutions, to improve patient outcomes.

bone regenerationdental implantsguided bone regenerationrhBMP-2maxillary sinus augmentation

Research Overview

Papers
34
Total Citations
44
Papers (5y)
9
Primary Field
Biochemistry, Genetics and Molecular Biology

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
9total
2017
2019
2020
2021
2023
Citations per year (5y)
5total
20172019202020212023

Selected Papers

15
1
Article|7 citations·2011
Developing an Effective Health Supplement for the Prevention of Osteoporosis
Ping‐Chung Leung, Erik Chun-hay Ko, Sammy Wing-sum Siu, Eun-Kyoung Pang, Eliza Lai‐Yi Wong, King-Fai Cheng
International Journal of Osteoporosis and Metabolic DisordersOA
GeneticsBiochemistry, Genetics and Molecular Biology
2
Article|5 citations·2016
Effects of Block Bone Substitutes Loaded with Escherichia Coli-Produced Recombinant Human Bone Morphogenetic Protein-2 on Space Maintenance and Bone Formation in Rat Calvarial Onlay Model
이재숙, 정겨운, 방은경
조직공학과 재생의학

We aimed to evaluate the effects of onlay-type grafted human freeze-dried corticocancellous bone block (FDBB) and deproteinized bovine bone with collagen (DBBC) loaded with Escherichia coli-produced recombinant human bone morphogenetic protein-2 (ErhBMP-2) on space maintenance and new bone formation in rat calvaria. Collagen sponge (CS), FDBB, or DBBC disks (8×4 mm) with ErhBMP-2 (2.5 μg) were implanted onto the calvaria of male Sprague-Dawley rats, whereas CS with buffer was implanted onto the

3
Article|4 citations·2019
임플란트 주위염의 유병률 및 위험요소분석에 관한 후향적 연구
이새은, 김대엽, 이종빈, 방은경
https://doi.org/10.4047/jkap.2019.57.1.8

목적: 본 연구의 목적은 최근 5년간 식립된 임플란트 증례를 대상으로 임플란트 주위염의 유병률을 조사하고, 질환 발생에 영향을 미칠 수 있는 요소들을 분석, 평가하는 것이다. 대상 및 방법: 2012년 1월 1일부터 2016년 12월 31일까지 이화여자대학교 의과대학 부속 목동병원 치과진료부 치주과에 내원한 환자 중 본원에서 임플란트를 식립하고 보철수복을 시행한 환자 422명(853개 임플란트)에 대한 의료기록과 방사선 사진을 바탕으로 임플란트 주위염의 유병률을 조사하고 임플란트 주위염에 영향을 미칠 수 있는 요소와의 연관성을 분석하였다. 각 위험요소와 임플란트 주위염의 통계적 연관성을 분석하기 위해 일반화 추정방정식(generalized estimation equations, GEE)을 사용하여 각 변수들과 임플란트 주위염의 발생 사이 상관관계를 평가하였다. 또한 관찰 기간 중 임플란트 주위염의 누적 유병률은 Kaplan Meier Method를 사용하였다. 결과: 임플란트 주위염

4
Article|4 citations·2007
상악동 골이식술을 동반한 임플란트 식립 시 골이식재의 높이 변화에 대한 방사선학적 평가
김지선, 이서경, 채경준, 정의원, 김창성, 최성호, 조규성, 채중규, 김종관, 방은경

The edentulous posterior maxilla generally provides a limited amount of bone height because of atrophy of the ridge and pneumatization of the maxillary sinus. Maxillary sinus augmentation is one of the surgical techniques for reconstruction of the severely resorbed posterior maxilla. The purpose of this study was to evaluate the survival rate of implants and the long-term changes of graft height after maxillary sinus augmentation by lateral window approach. From September 1996 to July 2004, maxi

5
Article|3 citations·2016
Comparison of the Oral Health Education Effect of Air Force Personnel according to the Use of Disclosing Solution
Hyerim Lee, Gyu-Un Jung, Eun-Kyoung Pang
The Journal of The Korean Dental AssociationOA

This study was to evaluate the effects of oral health education conducted on air force personnel according to the use of disclosing solution. They were divided into 3 groups: Group A: oral health education was not conducted, Group B: oral health education was conducted without using disclosing solution, and Group C: oral health education was conducted using disclosing solution. The subjects who had not participated in the education at least once were excluded, and the remaining 83 subjects recei

Ocean EngineeringEngineering
6
Article|3 citations·2015
Rapid bone regeneration by Escherichia coli-derived recombinant human bone morphogenetic protein-2 loaded on a hydroxyapatite carrier in the rabbit calvarial defect model
정정훈, 김유경, 이중석, 정의원, 방은경, 최성호
http://www.biomaterialsres.com/content/pdf/s40824-015-0039-x.pdf

Background: The aim of this study was to determine the osteoconductivity of hydroxyapatite particles (HAP) as a carrier for Escherichia coli-derived recombinant human bone morphogenetic protein-2 (ErhBMP-2). Two 8-mm diameter bicortical calvarial defects were created in each of 20 rabbits. One of each pair of defects was randomly assigned to be filled with HAP only (HAP group) or ErhBMP-2 loaded HAP (ErhBMP-2/HAP group), while the other defect was left untreated (control group). The animals were

7
Article|3 citations·2016
Histomorphometric Evaluation of Onlay Freeze-Dried Block Bone and Deproteinized Bovine Bone with Collagen in Rat
정겨운, 홍성진, 홍지연, 방은경
조직공학과 재생의학

The aim of this study was to evaluate the effect of human freeze-dried bone block (FDBB) and deproteinized bovine bone with collagen (DBBC) on bone formation when applied as an onlay graft in rat calvariums. Thirty male Sprague-Dawley rats received collagen sponge (control), FDBB, or DBBC onlay grafts trimmed into 8-mm disks measuring 4-mm height. Each graft was secured onto the calvarium surface using horizontal mattress sutures. Rats in each group were killed at 2 (n=5) or 8 (n=5) weeks postop

8
Article|2 citations·2015
비스포스포네이트 관련 악골괴사(Bisphosphonate-Related Osteonecrosis of the Jaw)에 관한 의사의 인식도 조사
김진우, 정수라, 방은경, 김선종

The objective of this study was to identify bisphosphonate-related osteonecrosis of the jaw (BRONJ) awareness and experience level of patients by medical doctors who prescribes bisphosphonate being used, analyze dental examination referral reality and to utilize its result as basic education data for early diagnosis of BRONJ and its prevention. The study was carried out through a self-administered questionnaire distributed among a sample 192 residents and specialists. They belonged to family med

9
Article|2 citations·2014
Anterior maxillary defect reconstruction with a staged bilateral rotated palatal graft
정겨운, 방은경, 박창주

Purpose: In the anterior maxilla, hard and soft tissue augmentations are sometimes requiredto meet esthetic and functional demands. In such cases, primary soft tissue closureafter bone grafting procedures is indispensable for a successful outcome. This report describesa simple method for soft tissue coverage of a guided bone regeneration (GBR) siteusing the double-rotated palatal subepithelial connective tissue graft (RPSCTG) techniquefor a maxillary anterior defect. Methods: We present a 60-yea

10
Article|2 citations·2014
Effects of adjunctive daily phototherapy on chronic periodontitis: a randomized single-blind controlled trial
정겨운, 김진우, 김선종, 방은경

Purpose: The purpose of this randomized single-blind controlled trial was to elucidate theclinical and antimicrobial effects of daily phototherapy (PT) as an adjunct to scaling androot planing (SRP) in patients with chronic periodontitis. Methods: The study was conducted from December 2013 to May 2014 at Ewha WomansUniversity Mokdong Hospital, Seoul, Korea. Forty-one patients with mild to moderatechronic periodontitis were randomly divided into two therapeutic groups in a 1:1 ratio:SRP+PT and SR

11
Article|2 citations·2015
The Effect of Human Freeze Dried Corticocancellous Block onlay Graft on Bone Formation in Rat Calvarium
정혜진, 방은경, 정겨운, 홍지연
조직공학과 재생의학

The aim of this study was to investigate the effect of an onlay graft of human freeze dried corticocancellousbone block (FDBB) on bone formation and the added effects of collagen membrane (CM) in rat calvarium. Thirty male Sprague-Dawley rats were treated with either collagen sponge (CS), FDBB or FDBB with CM. FDBBswere placed on the calvarium surface with the CM covered or not. Rats were sacrificed at 2 and 8 weeks after surgeryfor histologic and histomorphometric analysis. At each period, tota

12
Article|2 citations·2015
The Effects of Platelet-Rich Plasma on the Proliferation and Release of Growth Factors from Periodontal Ligament Cells
정겨운, 이선경, 지숙, 방은경
조직공학과 재생의학

Periodontal ligament cells (PDLCs) play an important role in the regeneration of periodontium. The healing potential of PDLCs may be due to the high concentration of growth factors in platelet-rich plasma (PRP). In this study, the effects of PRP on the proliferation and activation of PDLCs and growth factor release from PDLCs were investigated. PDLCs were isolated from third molars or premolars of healthy patients. Whole blood was obtained from healthy volunteers for the preparation of activated

13
Article|1 citations·2008
골 유도 재생술 후 감소된 임플란트 주위 부착 각화 점막 증대를 위한 유리 치은 이식술 증례
김득한, 방은경, 지숙

Purpose: During guided bone regeneration procedures for the augmentation of deficient alveolar ridge, primary closure of flap is necessary. For primary flap closure, flap is repositioned coronally and the zone of attached keratinized mucosa may decreased. The need for attached keratinized mucosa around dental implants is still controversial, but sufficient peri-implant attached keratinized mucosa would be beneficial for functional and esthetic aspects. This case report presents three cases that

14
Article|1 citations·2014
구리 합금 초음파 스케일러 팁이 치과 임플란트 및 수복 재료 표면에 미치는 영향
이아름, 정정훈, 정겨운, 방은경
http://dx.doi.org/10.4047/jkap.2014.52.3.177

본 연구는 구리 합금 스케일러 팁을 비롯한 수종의 스케일러 팁이 임플란트와 수복물 재료 표면에 실제 치석제거 시와 같이 적용하였을 때 표면 거칠기에 미치는 영향을 알아보고자 하였다. 재료 및 방법: 도재, 티타늄, 지르코니아, 제3형 금합금의 지름 15 mm, 높이 1.5 mm의 원반형 시편을 준비하였고, 거칠기 형성기구로 스테인리스 스틸팁(SS), 플라스틱 수동 큐렛(PS), 구리 합금 팁(IS)을 이용하였으며, 시편의 개수는 각 재료 당 기구 별로 4개씩 총 64개를 사용하였다. 표면 거칠기는 40 g의 힘으로 초음파 스케일러는 시편의 표면과 팁이 15도, 핸드 큐렛은 시편의 표면과 큐렛의 날이 45도가 되도록 하여 1초에 1회 5 mm 수평 왕복 운동을 30초 동안 시행하여 형성하였다. 각 시편을 주사전자 현미경을 이용하여 관찰하였고, 원자현미경과 표면조도 거칠기 단 차 측정기를 이용하여 표면 거칠기(Ra, ㎛)를 측정하고 분석하였다. 결과: 주사전자 현미경으로 관찰 결과 표면

15
Article|1 citations·2009
백서 두개골 결손부에서 동결건조골과 gel/putty 형 탈회골기질의 골재생효과
김득한, 홍지연, 방은경

Purpose: This study was aimed to evaluate the effect of the Freeze Dried Bone Allograft and Demineralized Bone Matrix on osseous regeneration in the rat calvarial defects. Methods: Eight mm critical-sized calvarial defects were created in the 80 male Sprague-Dawley rats. The animals were divided into 4 groups of 20 animals each. The defects were treated with Freeze Dried Bone Allograft(SureOss ™ ), Demineralized Bone Matrix(ExFuse ™ Gel, ExFuse ™ Putty), or were left untreated for sham-surgery c

Research Areas

GeneticsOcean Engineering

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