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Gap-Soo Kim

Sungkyunkwan University · Medicine

About the Lab

Professor Gap-Soo Kim's research lab specializes in transplant surgery and perioperative critical care, with a strong focus on improving outcomes in liver transplantation. The lab investigates key factors influencing post-transplant survival, including blood transfusion practices, cardiac biomarkers, donor organ characteristics (such as donor sex), and anesthetic techniques in high-risk pediatric and adult patients. A central theme is optimizing patient selection and perioperative management to reduce complications and mortality, particularly in patients with hepatocellular carcinoma (HCC). The lab also explores the impact of blood conservation strategies—like leukoreduced autotransfusion—on oncological outcomes in advanced HCC.

liver transplantationhepatocellular carcinomaperioperative outcomesblood transfusioncardiac biomarkers

Research Overview

Papers
281
Total Citations
2,746
Papers (5y)
53
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
53total
2021
2022
2023
2024
2025
Citations per year (5y)
309total
20212022202320242025

Selected Papers

15
1
Article|30 citations·2016
Perioperative Fresh Red Blood Cell Transfusion May Negatively Affect Recipient Survival After Liver Transplantation
Sangbin Han, Ji Hye Kwon, Sun Hee Jung, Ji Young Seo, Yong Jun Jo, Jin Sung Jang, Seung Min Yeon, Sin Ho Jung, Justin Sangwook Ko, Mi Sook Gwak, Duck Cho, Hee Jeong Son
SJR Q1Annals of Surgery

Our findings suggest a potential negative impact of fresh RBC transfusion on the survival of patients undergoing liver transplantation.

SurgeryMedicine
2
Article|29 citations·2017
Preoperative cardiac troponin level is associated with all-cause mortality of liver transplantation recipients
Jungchan Park, Seung Hwa Lee, Sangbin Han, Hyun Sook Jee, Suk‐Koo Lee, Gyu‐Seong Choi, Gaab Soo Kim
SJR Q1PLoS ONEOA

This study was aimed to evaluate the association between preoperative high-sensitivity cardiac troponin I (hs-cTnI) level and mortality in patients undergoing liver transplantation (LT). From January 2011 to May 2016, preoperative hs-cTnI level was measured in consecutive 487 patients scheduled for LT. Patients with elevated preoperative hs-cTnI were compared with those who had normal level. The primary outcome was all-cause death in follow-up period of 30 days to 1 year after operation. Of the

Cardiology and Cardiovascular MedicineMedicine
3
Article|26 citations·2017
Risk of Post-transplant Hepatocellular Carcinoma Recurrence Is Higher in Recipients of Livers From Male Than Female Living Donors
Sangbin Han, Ju Dong Yang, Dong Hyun Sinn, Jong Man Kim, Gyu Sung Choi, Gangha Jung, Joonghyun Ahn, Seonwoo Kim, Justin Sangwook Ko, Mi Sook Gwak, Choon Hyuck David Kwon, Michael D. Leise
SJR Q1Annals of Surgery

OBJECTIVE: To evaluate the relationship between donor sex and hepatocellular carcinoma (HCC) recurrence after living donor liver transplantation. BACKGROUND: HCC shows a male predominance in incidence and recurrence after tumor resection due to sex differences in hepatic sex hormone receptors. There have been no studies evaluating the importance of donor sex on post-transplant HCC recurrence. METHODS: Of 384 recipients of livers, from living donors, for HCC: 104/120 who received grafts from fema

HepatologyMedicine
4
Article|25 citations·2003
Postoperative Outcome in Formerly Premature Infants undergoing Herniorrhaphy: Comparison of Spinal and General Anesthesia
Gaab Soo Kim, Jaegyok Song, Mi Sook Gwak, Mikyung Yang
SJR Q2Journal of Korean Medical ScienceOA

To compare the postoperative outcome according to the type of anesthesia, formerly prematured and high-risk infants who had received and weaned ventilator care preoperatively and had undergone inguinal herniorrhaphy were enrolled in this study. Immediate pre- and post-operative respiratory data which contained the lowest respiratory rates, SpO2, heart rates and the incidence of hypoxemia and bradycardia were collected with the incidence of ventilator care, application of continuous positive airw

Pulmonary and Respiratory MedicineMedicine
5
Article|23 citations·2011
Risk Factors for Postoperative Complications after Open Infrarenal Abdominal Aortic Aneurysm Repair in Koreans
Gaab Soo Kim, Hyun Joo Ahn, Won Ho Kim, Min Ji Kim, Sang Hyun Lee
SJR Q2Yonsei Medical JournalOA

A significant number of complications occurred after infrarenal AAA repair. Therefore, creating a protocol to identify and monitor high risk patients would improve postoperative care.

Pulmonary and Respiratory MedicineMedicine
6
Article|23 citations·2021
Blood Salvage and Autotransfusion With Single Leukoreduction Does Not Increase the Risk of Tumor Recurrence After Liver Transplantation for Advanced Hepatocellular Carcinoma
Ji‐Hye Kwon, Sangbin Han, Doyeon Kim, Joon Hee Kuk, Hyun Cho, Seonwoo Kim, Ju Dong Yang, Chul Kim, Jong Man Kim, Gyu Sung Choi, Jae‐Won Joh, Justin Sangwook Ko
SJR Q1Annals of Surgery

OBJECTIVE: The aim of this study was to determine whether autotransfusion of salvaged blood with single leukoreduction is associated with post-transplant tumor recurrence in patients with advanced hepatocellular carcinoma (HCC). BACKGROUND: Previous studies have consistently demonstrated the safety of autotransfusion of salvaged and leukoreduced blood during liver transplantation for HCC. However, the effects of this technique remained unknown for advanced HCC. METHODS: Of 349 patients who under

HepatologyMedicine
7
Article|21 citations·2008
The Effects of Prehydration on the Properties of Cerebrospinal Fluid and the Spread of Isobaric Spinal Anesthetic Drug
Byung Seop Shin, Justin Sang Ko, Mi Sook Gwak, Mikyung Yang, Chung Su Kim, Tae Soo Hahm, Sang Min Lee, Hyun Sung Cho, Sung Tae Kim, Ji Hye Kim, Gaab Soo Kim
SJR Q1Anesthesia & Analgesia

Rapid crystalloid prehydration can affect CSF flow in the lumbar region, reducing cephalic spread of 0.5% isobaric tetracaine and delaying the time to reach the peak sensory level.

Cellular and Molecular NeuroscienceNeuroscience
8
Article|21 citations·2014
Rebalanced hemostasis in patients with idiopathic thrombocytopenic purpura
Won Ho Kim, Jung Bo Park, Chul Won Jung, Gaab Soo Kim
SJR Q2Platelets

Previous laboratory and clinical data have shown evidence for the concept of rebalanced hemostasis in liver disease. We evaluate whether this concept of rebalanced hemostasis can be applied in patients with idiopathic thrombocytopenic purpura (ITP). Twenty patients with ITP (platelet count < 100 × 10(9) /l) who visited our hospital were enrolled. We measured the von Willebrand factor (vWF) antigen levels and performed native blood thromboelastography (TEG) to evaluate the hemostasis. As a subgro

HematologyMedicine
9
Article|17 citations·2019
Prediction of postoperative pain and analgesic requirements using surgical pleth index: a observational study
MiHye Park, Byungjun Kim, Gaab Soo Kim
SJR Q2Journal of Clinical Monitoring and Computing
SurgeryMedicine
10
Article|15 citations·2021
Second generation laryngeal mask airway during laparoscopic living liver donor hepatectomy: a randomized controlled trial
Doyeon Kim, Sukhee Park, Jong Man Kim, Gyu‐Seong Choi, Gaab Soo Kim
SJR Q1Scientific ReportsOA

Abstract The second-generation laryngeal mask airway (LMA) provides a higher sealing pressure than classical LMA and can insert the gastric drainage tube. We investigated the difference in respiratory variables according to the use of second-generation LMA and endotracheal tube (ETT) in laparoscopic living liver donor hepatectomy (LLDH). In this single-blind randomized controlled trial, intraoperative arterial carbon dioxide partial pressure at 2 h after the airway devices insertion (P a CO 2_ 2

Anesthesiology and Pain MedicineMedicine
11
Article|10 citations·2018
Incidence and clinical significance of hyperfibrinolysis during living donor liver transplantation
Eun Hee Kim, Justin Sang Ko, Mi-Sook Gwak, Suk‐Koo Lee, Gaab Soo Kim
SJR Q3Blood Coagulation & Fibrinolysis

: We evaluated the incidence and clinical significance of hyperfibrinolysis during living donor liver transplantation (LDLT) using viscoelastic coagulation tests. We retrospectively reviewed adult LDLT recipients from February 2010 to February 2015. Hyperfibrinolysis was defined when clot lysis index [LY60 = (MA - A60)/MA × 100, %] was less than 85, where A60 is the clot amplitude at 60 min after maximum amplitude (MA) occurred. Viscoelastic coagulation tests were performed six times (T1: immedi

HepatologyMedicine
12
Article|10 citations·2016
Evaluation of New Calibrated Pulse-Wave Analysis (VolumeViewTM/EV1000TM) for Cardiac Output Monitoring Undergoing Living Donor Liver Transplantation
MiHye Park, Sangbin Han, Gaab Soo Kim, Mi Sook Gwak
SJR Q1PLoS ONEOA

The calibrated pulse-wave analysis and intrapulmonary thermodilution failed to show acceptable interchangeability in terms of both estimating CO and tracking CO changes during living donor liver transplantation.

SurgeryMedicine
13
Article|10 citations·2007
도가사상의 페미니즘적 전망
김갑수
15
Article|9 citations·2016
Higher Bilirubin Levels of Healthy Living Liver Donors Are Associated With Lower Posttransplant Hepatocellular Carcinoma Recurrence
Sangbin Han, Ju Dong Yang, Dong Hyun Sinn, Justin Sangwook Ko, Jong Man Kim, Jun Chul Shin, Hee Jeong Son, Mi Sook Gwak, Jae‐Won Joh, Gaab Soo Kim
SJR Q1Transplantation

Hepatocellular carcinoma recurrence risk decreases in relation to the increase in total serum bilirubin level of healthy living donors without underlying hepatobiliary or hematological disorders. Further validation of bilirubin as a potent anticancer substance against HCC is warranted.

Molecular BiologyBiochemistry, Genetics and Molecular Biology

Research Areas

SurgeryHepatologyAnesthesiology and Pain MedicinePulmonary and Respiratory MedicineCardiology and Cardiovascular MedicineCritical Care and Intensive Care Medicine

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