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Gilsu Son

Korea University · Medicine

About the Lab

Professor Gilsu Son's research lab specializes in diagnostic and interventional radiology, with a strong focus on advanced medical imaging techniques for cancer detection, characterization, and prognosis. The lab investigates the integration of medical imaging with molecular and genomic data—particularly through radiogenomics and machine learning—to improve the accuracy of breast cancer and thyroid cancer diagnosis. Key research directions include the application of perfusion CT, MRI, and ultrasound techniques (such as CEUS and SMI) to assess tumor vascularity, lymph node involvement, and histologic features, as well as evaluating surgical outcomes in adrenal and thyroid cancers.

radiogenomicsmedical imagingbreast cancermachine learningperfusion CT

Research Overview

Papers
132
Total Citations
1,380
Papers (5y)
19
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
19total
2020
2021
2023
2024
2025
Citations per year (5y)
131total
20202021202320242025

Selected Papers

15
1
Article|97 citations·2014
Transoral periosteal thyroidectomy: cadaver to human
Hye Yoon Lee, Ji Young You, Sang Uk Woo, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae, Hoon Yub Kim
SJR Q1Surgical Endoscopy
SurgeryMedicine
2
Article|82 citations·2019
A Prospective Study on the Value of Ultrasound Microflow Assessment to Distinguish Malignant from Benign Solid Breast Masses: Association between Ultrasound Parameters and Histologic Microvessel Densities
Ah Young Park, Myoungae Kwon, Ok Hee Woo, Kyu Ran Cho, Eun Kyung Park, Sang Hoon, Sung Eun Song, Jeong Hyeon Lee, Jaehyung Cha, Gil Soo Son, Bo Kyoung Seo
SJR Q1Korean Journal of RadiologyOA

US microflow assessment using SMI and CEUS is valuable in distinguishing malignant from benign solid breast masses, and US vascular parameters are associated with histologic MVD.

Radiology, Nuclear Medicine and ImagingMedicine
3
Review|63 citations·2013
Lymphoma Affecting the Breast: A Pictorial Review of Multimodal Imaging Findings
Euddeum Shim, Sung Eun Song, Bo Kyoung Seo, Young‐Sik Kim, Gil Soo Son
SJR Q2Journal of Breast CancerOA

Hematological malignancies rarely affect the breast, and the majority of those that do are lymphomas. In this review, we describe the clinical aspects and multimodal imaging findings of breast lymphoma. We also illustrate the key clinical and radiological findings that allow it to be distinguished from various other malignant and benign diseases of the breast. Breast lymphoma manifests as a breast mass, a change in the subcutaneous tissue or the skin, or enlargement of the associated lymph node

Pathology and Forensic MedicineMedicine
4
Article|53 citations·2015
Computer-aided detection (CAD) system for breast MRI in assessment of local tumor extent, nodal status, and multifocality of invasive breast cancers: preliminary study
Sung Eun Song, Bo Kyoung Seo, Kyu Ran Cho, Ok Hee Woo, Gil Soo Son, Chulhan Kim, Sung Bum Cho, Soon-Sun Kwon
SJR Q1Cancer ImagingOA

BACKGROUND: We aimed to investigate the efficacy of computer-aided detection (CAD) for MRI in the assessment of tumor extent, lymph node status, and multifocality in invasive breast cancers in comparison with other breast imaging modalities. METHODS: Two radiologists measured the maximum tumor size, as well as, analyzed lymph node status and multifocality in 86 patients with invasive breast cancers using mammography, ultrasound, CT, MRI with and without CAD, and 18-fludeoxyglucose positron emiss

Radiology, Nuclear Medicine and ImagingMedicine
5
Article|52 citations·2015
Thermal injury of the recurrent laryngeal nerve by THUNDERBEAT during thyroid surgery: findings from continuous intraoperative neuromonitoring in a porcine model
Hee Yong Kwak, Gianlorenzo Dionigi, Dasom Kim, Hye Yoon Lee, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae, Hoon Yub Kim
SJR Q1Journal of Surgical Research
SurgeryMedicine
6
Article|50 citations·2015
Should central lymph node dissection be considered for all papillary thyroid microcarcinoma?
Young Woo Chang, Hwan Soo Kim, Hoon Yub Kim, Jae Bok Lee, Jeoung Won Bae, Gil Soo Son
SJR Q2Asian Journal of SurgeryOA

CLNM in PTMC is highly prevalent in male sex, tumor size ≥ 0.5 cm, extrathyroidal extension, and multifocality. Even in PTMC patients without these risk factors, the incidence of CLNM is rather higher than expected, and the complication rate of thyroidectomy with CLND is acceptable. Thus, CLND should be considered in all patients with PTMC.

Endocrinology, Diabetes and MetabolismMedicine
7
Article|50 citations·2019
Machine Learning Approaches to Radiogenomics of Breast Cancer using Low-Dose Perfusion Computed Tomography: Predicting Prognostic Biomarkers and Molecular Subtypes
Eun Kyung Park, Kwang‐Sig Lee, Bo Kyoung Seo, Kyu Ran Cho, Ok Hee Woo, Gil Soo Son, Hye Yoon Lee, Young Woo Chang
SJR Q1Scientific ReportsOA

Radiogenomics investigates the relationship between imaging phenotypes and genetic expression. Breast cancer is a heterogeneous disease that manifests complex genetic changes and various prognosis and treatment response. We investigate the value of machine learning approaches to radiogenomics using low-dose perfusion computed tomography (CT) to predict prognostic biomarkers and molecular subtypes of invasive breast cancer. This prospective study enrolled a total of 723 cases involving 241 patien

Radiology, Nuclear Medicine and ImagingMedicine
8
Article|48 citations·2013
Comparison of robotic adrenalectomy with traditional laparoscopic adrenalectomy with a lateral transperitoneal approach: a single‐surgeon experience
Ji Young You, Hye Yoon Lee, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae, Hoon Yub Kim
SJR Q2International Journal of Medical Robotics and Computer Assisted Surgery

BACKGROUND: Although several recent studies have demonstrated the feasibility and safety of robotic adrenalectomy, it is unknown whether this procedure has advantages over the traditional laparoscopic approach. This study compared our initial experience using the da Vinci-S® robotic surgical system during laparoscopic adrenalectomy with our experience with traditional laparoscopic adrenalectomy. METHODS: From October 2009 to May 2012, 23 consecutive patients (13 women, 10 men) underwent laparosc

SurgeryMedicine
9
Article|47 citations·2004
BRCA1 andBRCA2 germline mutations in Korean patients with sporadic breast cancer
Jae Hong Seo, Dae-Yeon Cho, Se-Hyun Ahn, Kyung‐Sik Yoon, Chang-Soo Kang, Hyun Mi Cho, Hyeon Sook Lee, Jae Jin Choe, Chul Won Choi, Byung Soo Kim, Sang Won Shin, Yeul Hong Kim
SJR Q1Human MutationOA

In order to evaluate the role of BRCA1 and BRCA2 germline mutations in Korean patients with sporadic breast cancer, 97 patients with sporadic breast cancer were analyzed for mutations in the BRCA1 and BRCA2 coding regions, by using a combination of fluorescent-conformation sensitive gel electrophoresis (F-CSGE) and direct sequencing. Fifty-five distinct sequence variants were detected, which included three pathogenic truncating mutations, 15 missense mutations, 16 polymorphisms, and 21 intronic

GeneticsBiochemistry, Genetics and Molecular Biology
10
Article|46 citations·2014
Robotic thyroidectomy using bilateral axillo-breast approach: Comparison of surgical results with open conventional thyroidectomy
Hee Yong Kwak, Hoon Yub Kim, Hye Yoon Lee, Seung Pil Jung, Sang Uk Woo, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae
SJR Q1Journal of Surgical Oncology

Robotic thyroidectomy using BABA may be a technically feasible and safe procedure comparable to conventional open surgery especially in node-negative patients.

SurgeryMedicine
11
Article|39 citations·2006
High-avidity antitumor T-cell generation by toll receptor 8–primed, myeloid- derived dendritic cells is mediated by IL-12 production
Shuwen Xu, Ursula Koldovsky, Min Xu, Daniel Wang, Elizabeth Fitzpatrick, Gil‐Soo Son, Gary K. Koski, Brian J. Czerniecki
SJR Q1Surgery
ImmunologyImmunology and Microbiology
12
Article|38 citations·2018
Extent of central lymph node dissection for papillary thyroid carcinoma in the isthmus
Young Woo Chang, Hye Yoon Lee, Hwan Soo Kim, Hoon Yub Kim, Jae Bok Lee, Gil Soo Son
SJR Q2Annals of Surgical Treatment and ResearchOA

PURPOSE: The incidence of papillary thyroid carcinoma (PTC) arising from the isthmus is low; however, these tumors have aggressive clinical and pathological features. Moreover, the existing guidelines regarding the extent of surgery for this type of tumor are unclear. METHODS: This study enrolled 282 patients who underwent total thyroidectomy with bilateral central lymph node dissection. The patients were divided into 2 groups based on the location of the median line of the PTC. Group I included

Endocrinology, Diabetes and MetabolismMedicine
13
Article|35 citations·2008
Exophytic inflammatory myofibroblastic tumor of the stomach in an adult woman: A rare cause of hemoperitoneum
Seong-Heum Park, Jong-Han Kim, Byung Wook Min, Tae-Jin Song, Gil Soo Son, Seung Joo Kim, Sang Woo Lee, Hwan-Hoon Chung, Jeong Hyeon Lee, Jun Won Um
SJR Q1World Journal of GastroenterologyOA

Inflammatory myofibroblastic tumor (IMT) of the stomach in adults is extremely rare, with unpredictable prognosis. We present a 55-year-old woman with a gastric IMT. She experienced sudden abdominal pain 4 d previously. Physical examination showed mild abdominal tenderness in the hypogastrium, but no palpable abnormal abdominal mass. Abdominal CT showed a mass of approximately 8 cm in the gastrocolic ligament. On laparoscopic exploration, unexpected hemoperitoneum of approximately 1.5 L of blood

RheumatologyMedicine
14
Article|31 citations·2019
Detailed comparison of robotic and endoscopic transaxillary thyroidectomy
Young Woo Chang, Hye Yoon Lee, Woong Bae Ji, Hoon Yub Kim, Woo Young Kim, Jae Bok Lee, Gil Soo Son
SJR Q2Asian Journal of SurgeryOA

Compared to endoscopic thyroidectomy, robotic transaxillary thyroidectomy involved a shorter time for inferior pole dissection and PTGs and RLN identification; moreover, more PTGs were spared using this procedure.

SurgeryMedicine
15
Article|17 citations·2016
Pre-ablation stimulated thyroglobulin is a better predictor of recurrence in pathological N1a papillary thyroid carcinoma than the lymph node ratio
Young Woo Chang, Hwan Soo Kim, Seung Pil Jung, Hoon Yub Kim, Jae Bok Lee, Jeoung Won Bae, Gil Soo Son
SJR Q1International Journal of Clinical Oncology
Endocrinology, Diabetes and MetabolismMedicine

Research Areas

SurgeryEndocrinology, Diabetes and MetabolismCancer ResearchOncologyRadiology, Nuclear Medicine and ImagingPathology and Forensic Medicine

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