Giomoo Jang
Korea University · Medicine
About the Lab
Professor Giomoo Jang's research lab specializes in regenerative medicine and orthopedic tissue engineering, with a primary focus on mesenchymal stem cell therapy for musculoskeletal repair. The lab investigates non-autologous stem cell transplantation—particularly human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs)—to enhance bone-tendon healing and osteochondral regeneration in animal models. Key research directions include improving outcomes in anterior cruciate ligament reconstruction (ACLR) by addressing rotational instability through combined biological and structural approaches, and evaluating long-term neuromuscular recovery post-surgery. The lab also explores biomaterial scaffolds, such as platelet-rich fibrin glue and hydroxyapatite composites, to support stem cell delivery and tissue regeneration.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15PURPOSE: To investigate whether non-autologous transplantation of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) could be integrated safely at the bone-tendon junction without immune rejection and could enhance bone-tendon healing effectively during anterior cruciate ligament (ACL) reconstruction in an animal model. METHODS: ACL reconstructions using hamstring tendons were performed in 30 adult rabbits. The bone tunnels were treated with hUCB-MSCs or were untreated. The sp
Citrulline supplements significantly reduced post-exercise RPE and muscle soreness without affecting blood lactate levels.
This technique should be recommended because (1) it provides release of anterior column without anterior approach and (2) our results supports its superiority as a technique.
PURPOSE: The aim of this work is to investigate the feasibility of non-autologous transplantation of human mesenchymal stem cells (hMSCs) with or without differentiation for the regeneration of osteochondral defects in rabbits using a biphasic composite construct composed of platelet-rich fibrin glue (PR-FG) and hydroxyapatite. METHODS: After isolation and culture, hMSCs were seeded on biphasic composite constructs (hydroxyapatite + PR-FG) and transplanted into osteochondral defects of adult New
Despite remarkable advances in the clinical outcomes after anterior cruciate ligament reconstructions (ACLRs), residual rotational instability of the knee joint remains a major concern. Since the anterolateral ligament (ALL) on the knee joint has been "rediscovered", the role of anterolateral structures, including ALL and deep iliotibial band, as secondary stabilizers of anterolateral rotatory instability has gained interest. This interest has led to the resurgence of anterolateral procedures co
The current study was performed to assess serial changes in neuromuscular control until 1 year postoperatively in nonathletic patients undergoing anterior cruciate ligament reconstruction (ACLR).Ninety-six patients were included. Serial neuromuscular control tests were performed preoperatively, at 6 months, and 1 year postoperatively. Neuromuscular control was evaluated using acceleration time (AT) and dynamic postural stability (overall stability index, OSI). Functional activity levels were ass
BACKGROUND: To date, no in vivo 3-dimensional computed tomography (3D-CT) studies have compared graft bending angles at the femoral tunnel aperture and femoral tunnel length in patients who underwent posterior cruciate ligament (PCL) reconstruction with outside-in (OI) and inside-out (IO) techniques. PURPOSE/HYPOTHESIS: This study used in vivo 3D-CT analysis to compare graft bending angles at the femoral tunnel aperture and femoral tunnel lengths after OI and IO femoral drilling techniques in si
Research Areas
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