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Gyeong-Chul Moon

Korea University · Medicine

About the Lab

Professor Gyeong-Chul Moon's research lab focuses on regenerative medicine and translational biomedicine, with a strong emphasis on stem cell therapies for chronic wounds and microcirculatory disorders, particularly in diabetic patients. The lab investigates the clinical application of adipose-derived stem cells (ASCs) and stromal vascular fraction (SVF) cells to enhance tissue repair and perfusion in ischemic conditions. Additionally, the lab explores molecular mechanisms in rare and aggressive cancers, such as extrapulmonary neuroendocrine carcinomas and primary renal neuroendocrine tumors, using immunohistochemical and molecular profiling approaches. These diverse research directions converge on improving patient outcomes through innovative cellular therapies and precision oncology.

stem cell therapydiabetic wound healingmicrocirculationneuroendocrine tumorsregenerative medicine

Research Overview

Papers
102
Total Citations
2,357
Papers (5y)
31
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
31total
2021
2022
2023
2024
2025
Citations per year (5y)
185total
20212022202320242025

Selected Papers

15
1
Article|208 citations·2019
Potential of Allogeneic Adipose-Derived Stem Cell–Hydrogel Complex for Treating Diabetic Foot Ulcers
Kyung‐Chul Moon, Hyunsuk Peter Suh, Ki-Bum Kim, Seung‐Kyu Han, Ki-Won Young, Jin Woo Lee, Mi-Hyung Kim
SJR Q1DiabetesOA

Mesenchymal stem cells (MSCs) may hold great promise for treating diabetic wounds. However, it is difficult for a clinician to use MSCs because they have not been commercialized. Meanwhile, a new commercial drug that contains adipose-derived stem cells (ASCs) has been developed. The purpose of this study was to examine the potential of allogeneic ASC sheets for treating diabetic foot ulcers. Fifty-nine patients with diabetic foot ulcers were randomized to either the ASC treatment group (n = 30)

RehabilitationMedicine
2
Article|56 citations·2005
The Study of Hot-Carrier Stress on Poly-Si TFT Employing C–V Measurement
Kyung‐Chul Moon, Jae‐Hak Lee, Moon‐Ku Han
SJR Q2IEEE Transactions on Electron Devices

The degradation of n-type and p-type low-temperature polycrystalline silicon (poly-Si) thin-film transistors (TFTs) due to hot-carrier stress was investigated by capacitance-voltage (C-V) measurement. In C-V measurements, the fixed charges in the gate oxide of TFTs are not affected by a small-applied signal, whereas the trap states in the bandgap respond to the applied frequency, so that the dominant degradation mechanism of poly-Si TFTs can be evaluated. The capacitance (C/sub GS/) between the

Electrical and Electronic EngineeringEngineering
3
Review|36 citations·2018
Surgical Anatomy of the Asian Nose
Kyung‐Chul Moon, Seung‐Kyu Han
SJR Q1Facial Plastic Surgery Clinics of North America
SurgeryMedicine
4
Article|35 citations·2019
Possibility of Injecting Adipose-Derived Stromal Vascular Fraction Cells to Accelerate Microcirculation in Ischemic Diabetic Feet: A Pilot Study
Kyung‐Chul Moon, Ha-Yoon Chung, Seung‐Kyu Han, Seong‐Ho Jeong, Eun‐Sang Dhong
SJR Q3International Journal of Stem CellsOA

BACKGROUND AND OBJECTIVES: studies. However, no clinical studies have reported its effect in diabetic patients who commonly experience compromised tissue perfusion, regardless of the status of intravascular blood flow. The present piloting study was designed to clinically examine the possibility of SVF cell injection to accelerate microcirculation, particularly in ischemic diabetic feet. METHODS: week visit. RESULTS: values increased from 31.3±7.4 before injection to 46.4±8.2 mmHg at 12 weeks af

Endocrinology, Diabetes and MetabolismMedicine
5
Article|35 citations·2017
Effects of human umbilical cord blood–derived mesenchymal stromal cells and dermal fibroblasts on diabetic wound healing
Kyung‐Chul Moon, Jong Seok Lee, Seung‐Kyu Han, Hyup-Woo Lee, Eun‐Sang Dhong
SJR Q1Cytotherapy
RehabilitationMedicine
6
Article|29 citations·2019
Risk factors for major amputation in hospitalized diabetic patients with forefoot ulcers
Kyung‐Chul Moon, Soo-Byn Kim, Seung‐Kyu Han, Seong‐Ho Jeong, Eun‐Sang Dhong
SJR Q1Diabetes Research and Clinical Practice
Endocrinology, Diabetes and MetabolismMedicine
7
Article|28 citations·2019
Primary renal well-differentiated neuroendocrine tumors: report of six cases with an emphasis on the Ki-67 index and mitosis
Bohyun Kim, Han-Seong Kim, Kyung‐Chul Moon
SJR Q2Diagnostic PathologyOA

BACKGROUND: Primary renal well-differentiated neuroendocrine tumors (WDNETs) also called carcinoid and atypical carcinoid are extremely rare, and little is known about parameters that may predict prognosis at diagnosis. METHODS: Six cases of primary renal WDNET were collected. After reviewing slides stained with hematoxylin and eosin, proportions of each growth pattern were determined. Synaptophysin, chromogranin, CD56, and Ki-67 immunostaining and Ki-67 morphometric analysis were performed. RES

EpidemiologyMedicine
8
Article|28 citations·2022
Molecular Classification of Extrapulmonary Neuroendocrine Carcinomas With Emphasis on POU2F3-positive Tuft Cell Carcinoma
Jiwon Koh, Haeryoung Kim, Kyung‐Chul Moon, Chul Lee, Kyoungbun Lee, Han Suk Ryu, Kyeong Cheon Jung, Yoon Kyung Jeon
SJR Q1The American Journal of Surgical PathologyOA

Extrapulmonary neuroendocrine carcinomas (EP-NECs) are associated with a poor clinical outcome, and limited information is available on the biology and treatment of EP-NECs. We studied EP-NECs by applying the recent novel findings from studies of pulmonary neuroendocrine carcinomas, including POU2F3, the master regulator of tuft cell variant of small cell lung carcinomas. A cohort of 190 patients with surgically resected EP-NECs or poorly differentiated carcinomas (PDCs) were established. Immuno

EpidemiologyMedicine
9
Article|27 citations·2019
Risk Factors for Major Amputation on Hindfoot Ulcers in Hospitalized Diabetic Patients
Kyung‐Chul Moon, Ki-Bum Kim, Seung‐Kyu Han, Seong‐Ho Jeong, Eun‐Sang Dhong
SJR Q1Advances in Wound Care

Objective: The purpose of this study was to investigate the risk factors for major amputation in patients hospitalized with diabetic foot ulcers involving the hindfoot. Approach: Between January 2003 and October 2017, a total of 1,657 diabetic patients were admitted to the diabetic wound center of Korea University Guro Hospital, for the management of foot ulcers. Among the admitted patients, 117 diabetic patients with hindfoot ulcers were included in this study. One hundred and four patients (89

Endocrinology, Diabetes and MetabolismMedicine
10
Article|27 citations·2013
Modified Double-Eyelid Blepharoplasty Using the Single-Knot Continuous Buried Non-Incisional Technique
Kyung‐Chul Moon, Eul‐Sik Yoon, Jun-Mun Lee
SJR Q2Archives of Plastic SurgeryOA

BACKGROUND: Buried non-incisional double-eyelid blepharoplasty is a popular aesthetic procedure. Although various modified continuous suture techniques have been used to create a more natural appearance and to reduce downtime, complications such as loosening of the double fold, asymmetry, and foreign body reactions have been observed. METHODS: This study included 250 patients who underwent double-eyelid blepharoplasty between March 1997 and November 2012 using a modified single-knot continuous b

DermatologyMedicine
11
Article|27 citations·2018
Effects of Ultraviolet Irradiation on Cellular Senescence in Keratinocytes Versus Fibroblasts
Kyung‐Chul Moon, Jong-Phil Yang, Jae Sun Lee, Seongho Jeong, Eun‐Sang Dhong, Seung‐Kyu Han
SJR Q2Journal of Craniofacial Surgery

Aging is a biologic process characterized by time-dependent functional declines that are influenced by oxidative stress-induced inflammatory reactions. In particular, ultraviolet (UV) irradiation plays a key role in cellular senescence in photo-aged skin. However, the cellular senescence of epidermal keratinocytes and dermal fibroblasts by UV irradiation may differ depending on the exposure time and dosage of UV irradiation. Therefore, the purpose of the study was to evaluate and compare the eff

DermatologyMedicine
12
Article|17 citations·2019
Septorhinoplasty for Destructed Septal L-Strut in Patients with Previously Applied Porous High-Density Polyethylene Implants (Medpor®)
Kyung‐Chul Moon, Jae-Eun Jung, Eun‐Sang Dhong, Seong‐Ho Jeong, Seung‐Kyu Han
SJR Q1Aesthetic Plastic Surgery
SurgeryMedicine
13
Article|16 citations·2020
Robotic-assisted latissimus dorsi muscle flap for autologous chest reconstruction in poland syndrome
Kyung‐Chul Moon, Hyun-Dong Yeo, Eul‐Sik Yoon, B.I. Lee, S.H. Park, Jae‐Ho Chung, H.C. Lee
SJR Q1Journal of Plastic Reconstructive & Aesthetic Surgery
SurgeryMedicine
14
Article|15 citations·2019
Predictors affecting complications and aesthetic outcomes in autologous breast reconstruction with free muscle‐sparing transverse rectus abdominis myocutaneous flaps
Kyung‐Chul Moon, Si‐Ook Baek, Eul‐Sik Yoon, Byung‐Il Lee, Seung Ha Park
SJR Q1Microsurgery

BACKGROUND: Identification and understanding of predictors for complications and aesthetic outcomes in free muscle-sparing transverse rectus abdominis myocutaneous (MS-TRAM) flap are essential for successful breast reconstruction. The purpose of this study was to investigate predictors for complications and aesthetic outcomes in patients who underwent autologous breast reconstruction with free MS-TRAM flaps. PATIENTS AND METHODS: Between March 2003 and September 2017, a total of 214 patients who

SurgeryMedicine
15
Article|14 citations·2020
Preoperative Nasal Swab Culture: Is It Beneficial in Preventing Postoperative Infection in Complicated Septorhinoplasty?
Kyung‐Chul Moon, Jae-Eun Jung, Eun‐Sang Dhong, Seong‐Ho Jeong, Seung‐Kyu Han
SJR Q1Plastic & Reconstructive Surgery

BACKGROUND: Surgical-site infection following complicated septorhinoplasty may result in serious complications. Therefore, efforts to prevent surgical-site infections after complicated septorhinoplasty are important. The purpose of this study was to analyze the microbiological profile of preoperative nasal swab cultures and to evaluate the effect of antibiotic prophylaxis and topical antibiotic decolonization according to the antibiotic sensitivity results of surgical-site infections in complica

SurgeryMedicine

Research Areas

SurgeryPulmonary and Respiratory MedicineAtmospheric ScienceEndocrinology, Diabetes and MetabolismOncologyRehabilitation

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