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Gyusun Choi

Hanyang University · Medicine

About the Lab

Professor Gyusun Choi's research lab specializes in cerebrovascular and neurosurgical disorders, with a strong focus on predicting and improving functional outcomes after acute brain injuries such as subarachnoid hemorrhage, intracerebral hemorrhage, and cardiac arrest. The lab investigates prognostic biomarkers—such as copeptin and brain atrophy parameters—alongside clinical risk factors to guide personalized treatment strategies. Key research directions include the evidence-based use of antiepileptic drugs, the impact of surgical approaches on outcomes, and the evaluation of advanced resuscitation techniques like ECPR in neurocritical care.

subarachnoid hemorrhageintracerebral hemorrhageprognostic biomarkersneurosurgical outcomesneurocritical care

Research Overview

Papers
93
Total Citations
1,544
Papers (5y)
30
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
30total
2022
2023
2024
2025
2026
Citations per year (5y)
224total
20222023202420252026

Selected Papers

15
1
Article|121 citations·2009
Seizures and Epilepsy following Aneurysmal Subarachnoid Hemorrhage : Incidence and Risk Factors
Kyu-Sun Choi, Hyoung-Joon Chun, Hyeong-Joong Yi, Yong Ko, Young‐Soo Kim, Jae-Min Kim
SJR Q2Journal of Korean Neurosurgical SocietyOA

Perioperative seizures are not significant predictors for late epilepsy. Instead, initial amount of SAH and surgery-induced cortical damage should be seriously considered as risk factors for late epilepsy. Because AEDs can not prevent early postoperative seizures (< 1 week) and potentially cause unexpected side effects, long-term use should be readjusted in high-risk patients.

NeurologyMedicine
2
Review|79 citations·2016
Efficacy of extracorporeal cardiopulmonary resuscitation compared to conventional cardiopulmonary resuscitation for adult cardiac arrest patients: a systematic review and meta-analysis
Chiwon Ahn, Wonhee Kim, Youngsuk Cho, Kyu-Sun Choi, Bo-Hyoung Jang, Tae Ho Lim
SJR Q1Scientific ReportsOA

We performed a meta-analysis to compare the impact of extracorporeal cardiopulmonary resuscitation (ECPR) to that of conventional cardiopulmonary resuscitation (CCPR) in adult patients who experience cardiac arrest of cardiac origin. A literature search was performed using criteria set forth in a predefined protocol. Report inclusion criteria were that ECPR was compared to CCPR in adult patients with cardiac arrest of cardiac origin, and that survival and neurological outcome data were available

Emergency MedicineMedicine
3
Article|42 citations·2018
Impact of brain atrophy on 90-day functional outcome after moderate-volume basal ganglia hemorrhage
Sae Min Kwon, Kyu-Sun Choi, Hyeong-Joong Yi, Yong Ko, Young‐Soo Kim, Koang Hum Bak, Hyoung-Joon Chun, Young‐Jun Lee, Ji Young Lee
SJR Q1Scientific ReportsOA

This study aimed to evaluate the effect of brain atrophy on the functional outcome of patients with moderate-volume basal ganglia hemorrhage. Of 1003 patients with spontaneous intracerebral hemorrhage, 124 with moderate-volume basal ganglia hemorrhage (hematoma volume of 20-50 mL) were enrolled. The intercaudate distance (ICD) and sylvian fissure ratio (SFR) were used as linear brain atrophy parameters. The patients were divided into groups with favorable and unfavorable outcomes, according to t

NeurologyMedicine
4
Article|41 citations·2009
Seizures and Epilepsy following Aneurysmal Subarachnoid Hemorrhage : Incidence and Risk Factors
최규선, 전형준, 고용, 김영수, 김재민, 이형중
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=1001920090460020093

Objective : Although prophylactic antiepileptic drug (AED) use in patients with aneurysmal subarachnoid hemorrhage (SAH) is a common practice, lack of uniform definitions and guidelines for seizures and AEDs rendered this prescription more habitual instead of evidence-based manner. We herein evaluated the incidence and predictive factors of seizure and complications about AED use. Methods : From July 1999 to June 2007, data of a total of 547 patients with aneurysmal SAH who underwent operative t

5
Review|39 citations·2015
Prognostic role of copeptin after stroke: A systematic review and meta-analysis of observational studies
Kyu-Sun Choi, Hyun Jung Kim, Hyoung-Joon Chun, Jae Min Kim, Hyeong-Joong Yi, Jin Hwan Cheong, Choong-Hyun Kim, Suck-Jun Oh, Yong Ko, Young Soo Kim, Koang Hum Bak, Je-Il Ryu
SJR Q1Scientific ReportsOA

Copeptin, the C-terminal part of provasopressin, has emerged as a novel prognostic marker after hemorrhagic or ischemic stroke. The aim of this study was to quantitatively assess the prognostic significance of plasma copeptin level on functional outcome and mortality in patients with acute stroke using a meta-analysis of the available evidence. Thirteen relevant studies from 2,746 patients were finally included in our study. An elevated plasma copeptin level was associated with an increased risk

Pulmonary and Respiratory MedicineMedicine
6
Review|37 citations·2022
Craniopharyngioma resection by endoscopic endonasal approach versus transcranial approach: A systematic review and meta-analysis of comparative studies
Min Kyun Na, Bo-Hyoung Jang, Kyu-Sun Choi, Tae Ho Lim, Wonhee Kim, Youngsuk Cho, Hyungoo Shin, Chiwon Ahn, Jae Guk Kim, Juncheol Lee, Sae Min Kwon, Heekyung Lee
SJR Q2Frontiers in OncologyOA

Introduction: The transcranial approach (TCA) has historically been used to remove craniopharyngiomas. Although the extended endoscopic endonasal approach (EEA) to these tumors has been more commonly accepted in the recent two decades, there is debate over whether this approach leads to better outcomes. The goal of this systematic review and meta-analysis was to more comprehensively understand the benefits and limitations of these two approaches in craniopharyngioma resection based on comparativ

Endocrinology, Diabetes and MetabolismMedicine
7
Article|33 citations·2018
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model
Kyu-Sun Choi, Han‐Jun Kim, Sun Hee, Se Jin Hwang, Hyeong-Joong Yi
SJR Q2Brain Research Bulletin
SurgeryMedicine
8
Article|33 citations·2013
Therapeutic and prognostic implications of subarachnoid hemorrhage in patients who suffered cardiopulmonary arrest and underwent cardiopulmonary resuscitation during an emergency room stay
Kyu-Sun Choi, Yu Deok Won, Hyeong-Joong Yi, Tae Ho Lim, Young‐Jun Lee, Hyoung-Joon Chun
SJR Q2Clinical Neurology and Neurosurgery
Emergency MedicineMedicine
9
Article|29 citations·2014
Incidence and risk factors of postoperative headache after endovascular coil embolization of unruptured intracranial aneurysms
Kyu-Sun Choi, Jung-Hyun Lee, Hyeong-Joong Yi, Hyoung-Joon Chun, Young‐Jun Lee, Dong-Won Kim
SJR Q1Acta Neurochirurgica
NeurologyMedicine
10
Review|26 citations·2017
Prognostic role of copeptin after traumatic brain injury: A systematic review and meta-analysis of observational studies
Kyu-Sun Choi, Youngsuk Cho, Bo-Hyoung Jang, Wonhee Kim, Chiwon Ahn, Tae Ho Lim, Hyoung-Joong Yi
SJR Q1The American Journal of Emergency Medicine
Pulmonary and Respiratory MedicineMedicine
11
Review|21 citations·2018
Efficacy and safety of erythropoietin in patients with traumatic brain injury: A systematic review and meta-analysis
Juncheol Lee, Youngsuk Cho, Kyu-Sun Choi, Wonhee Kim, Bo-Hyoung Jang, Hyungoo Shin, Chiwon Ahn, Tae Ho Lim, Hyeong-Joong Yi
SJR Q1The American Journal of Emergency Medicine
HematologyMedicine
12
Article|15 citations·2022
Immediately implantable extracellular matrix-enriched osteoinductive hydrogel-laden 3D-printed scaffold for promoting vascularized bone regeneration in vivo
Jae Seo Lee, Haram Nah, Donghyun Lee, Sang‐Hyun An, Wan‐Kyu Ko, Sang Jin Lee, Seung Yeon Lee, Kyung Min Park, Jung Bok Lee, Hyeong-joong Yi, Il Keun Kwon, Kyu-Sun Choi
SJR Q1Materials & DesignOA

Reconstruction of patient-specific scaffolds to repair uniquely shaped bone defects remains a major clinical challenge in tissue engineering. Recently, three-dimensional (3D) printed scaffolds have received considerable attention as a promising technology for the rapid generation of custom shapes. However, synthetic polymers commonly used for 3D printing, such as polycaprolactone (PCL), lack the biological capacity to mimic native extracellular matrix functions to support cell growth and differe

Biomedical EngineeringEngineering
13
Review|8 citations·2017
Dose-related effect of statins in patients with endovascular coiling or microsurgical clipping for aneurysmal subarachnoid hemorrhage: updated study-level meta-analysis
Kyu-Sun Choi, Jae Min Kim, Hyeong-Joong Yi, Seon Heui Lee, Tae Ho Lim, Wonhee Kim, Youngsuk Cho, Jin Hwan Cheong
SJR Q2European Journal of Clinical PharmacologyOA
NeurologyMedicine
14
erratum|6 citations·2017
Erratum to: Dose-related effect of statins in patients with endovascular coiling or microsurgical clipping for aneurysmal subarachnoid hemorrhage: updated study-level meta-analysis
Kyu-Sun Choi, Jae Min Kim, Hyeong-Joong Yi, Seon Heui Lee, Tae Ho Lim, Wonhee Kim, Youngsuk Cho, Jin Hwan Cheong
SJR Q2European Journal of Clinical PharmacologyOA
NeurologyMedicine
15
Article|6 citations·2015
Concurrent Ruptured Pseudoaneurysm of the Internal Carotid Artery and Cerebral Infarction as an Initial Manifestation of Polycythemia Vera
Kyu-Sun Choi, Jae Min Kim, Je-Il Ryu, Young‐Ha Oh
SJR Q2Journal of Korean Neurosurgical SocietyOA

cular diseases. She was in normotensive and in sinus rhythm. A computed tomography (CT) scan revealed SAH on left basal cistern (Fig. Magnetic resonance (MR) images showed an acute ischemic lesion in the territory of the left middle cerebral artery with restricted diffusion (Fig. Digital subtraction angiography (DSA) demonstrated an irregularly shaped aneurysm arising from left supraclinoid ICA with moderate stenosis of proximal region (Fig. Moreover, DSA revealed one of the typical findings of

GeneticsMedicine

Research Areas

NeurologyEmergency MedicineSurgeryPulmonary and Respiratory MedicinePathology and Forensic MedicineCardiology and Cardiovascular Medicine

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