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Hee Dong Chae

Seoul National University · Medicine

About the Lab

Professor Hee Dong Chae's research lab specializes in medical imaging and diagnostic radiology, with a focus on improving the accuracy of non-invasive diagnosis through advanced imaging techniques and artificial intelligence. The lab investigates texture analysis in lung nodules, fat-signal fraction mapping for bone lesion characterization, and deep learning applications in ultrasound-based differentiation of gallbladder polyps. Additionally, the lab explores minimally invasive interventional radiology procedures, such as transvaginal radiofrequency myolysis, and evaluates hormonal interventions in reproductive medicine.

medical imagingdeep learningradiological diagnosisultrasound-guided interventiontexture analysis

Research Overview

Papers
119
Total Citations
1,959
Papers (5y)
19
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
19total
2022
2023
2024
2025
2026
Citations per year (5y)
92total
20222023202420252026

Selected Papers

15
1
Article|224 citations·2014
Computerized Texture Analysis of Persistent Part-Solid Ground-Glass Nodules: Differentiation of Preinvasive Lesions from Invasive Pulmonary Adenocarcinomas
Hee‐Dong Chae, Chang Min Park, Sang Joon Park, Sang Min Lee, Kwang Gi Kim, Jin Mo Goo
SJR Q1Radiology

In part-solid GGNs, higher kurtosis and smaller mass are significant differentiators of preinvasive lesions from IPAs, and preinvasive lesions can be accurately differentiated from IPAs by using computerized texture analysis. Online supplemental material is available for this article.

Pulmonary and Respiratory MedicineMedicine
2
Article|170 citations·2010
Effect of levothyroxine treatment on in vitro fertilization and pregnancy outcome in infertile women with subclinical hypothyroidism undergoing in vitro fertilization/intracytoplasmic sperm injection
Chung‐Hoon Kim, Jun‐Woo Ahn, Sunjung Kang, Sung-Hoon Kim, Hee‐Dong Chae, Byung‐Moon Kang
SJR Q1Fertility and SterilityOA
Endocrinology, Diabetes and MetabolismMedicine
3
Article|157 citations·2006
Presence and Absence of Follicle-Stimulating Hormone Receptor Mutations Provide Some Insights into Spontaneous Ovarian Hyperstimulation Syndrome Physiopathology
Anne De Leener, Lucia Montanelli, Joost Van Durme, Hee‐Dong Chae, Guillaume Smits, Gilbert Vassart, Sabine Costagliola
SJR Q1The Journal of Clinical Endocrinology & Metabolism

sOHSS can occur by at least three different pathophysiological mechanisms.

Reproductive MedicineMedicine
4
Article|76 citations·2016
Measurement of fat content in vertebral marrow using a modified dixon sequence to differentiate benign from malignant processes
Hye Jin Yoo, Sung Hwan Hong, Dong Hyun Kim, Ja‐Young Choi, Hee‐Dong Chae, Bo Mi Jeong, Joong Mo Ahn, Heung Sik Kang
SJR Q1Journal of Magnetic Resonance ImagingOA

Purpose To determine whether fat‐signal‐fraction (FF) map using a modified Dixon sequence could help differentiate benign from malignant bone lesions. Materials and Methods Spine magnetic resonance images (MRIs) of 120 consecutive patients were studied by using a 3T MRI with standard T 1 ‐weighted image ( T 1 WI) and modified‐Dixon sequence for FF measurement. There were three groups: a control group ( n = 51) with normal vertebrae; a benign group ( n = 40) with focal red marrow deposition, Schm

Orthopedics and Sports MedicineMedicine
5
Article|74 citations·2011
Transvaginal ultrasound-guided radiofrequency myolysis for uterine myomas
Cheol Kim, S.-R. Kim, H.-A. Lee, Sung Hoon Kim, Hee‐Dong Chae, Byung Moon Kang
SJR Q1Human ReproductionOA

BACKGROUND: Myolysis is one of the procedures that is claimed to provide significant improvement in myoma status without hysterectomy. Myolysis procedures have been generally performed via laparoscopy, and there are limited data on transvaginal radiofrequency (RF) myolysis. This study investigated the feasibility, efficacy and safety of transvaginal ultrasound-guided RF myolysis. METHODS: Transvaginal ultrasound-guided RF myolysis was performed on 69 premenopausal women with symptomatic uterine

Obstetrics and GynecologyMedicine
6
Article|61 citations·2014
The effect of luteal phase progesterone supplementation on natural frozen-thawed embryo transfer cycles
Chung‐Hoon Kim, You‐Jeong Lee, Kyung‐Hee Lee, Su-Kyung Kwon, Sung Hoon Kim, Hee‐Dong Chae, Byung‐Moon Kang
SJR Q2Obstetrics & Gynecology ScienceOA

Our results suggest that luteal phase progesterone supplementation decreases miscarriage rate and improves live birth rate in natural FTET cycles.

Public Health, Environmental and Occupational HealthMedicine
7
Article|55 citations·2020
The Value of Preprocedural MR Imaging in Genicular Artery Embolization for Patients with Osteoarthritic Knee Pain
Jin Woo Choi, Du Hyun Ro, Hee‐Dong Chae, Dong Hyun Kim, Myungsu Lee, Saebeom Hur, Hyo‐Cheol Kim, Hwan Jun Jae, Jin Wook Chung
SJR Q2Journal of Vascular and Interventional Radiology
SurgeryMedicine
8
Article|50 citations·2020
Deep learning-based decision support system for the diagnosis of neoplastic gallbladder polyps on ultrasonography: Preliminary results
Younbeom Jeong, Jung Hoon Kim, Hee‐Dong Chae, Sae‐Jin Park, Jae Seok Bae, Ijin Joo, Joon Koo Han
SJR Q1Scientific ReportsOA

Ultrasonography (US) has been considered image of choice for gallbladder (GB) polyp, however, it had limitations in differentiating between nonneoplastic polyps and neoplastic polyps. We developed and investigated the usefulness of a deep learning-based decision support system (DL-DSS) for the differential diagnosis of GB polyps on US. We retrospectively collected 535 patients, and they were divided into the development dataset (n = 437) and test dataset (n = 98). The binary classification convo

SurgeryMedicine
9
Article|50 citations·2019
Performance of a Deep Learning Algorithm in Detecting Osteonecrosis of the Femoral Head on Digital Radiography: A Comparison With Assessments by Radiologists
Choong Guen Chee, Youngjune Kim, Yusuhn Kang, Kyong Joon Lee, Hee‐Dong Chae, Jungheum Cho, Chang-Mo Nam, Dongjun Choi, Eugene Lee, Joon Woo Lee, Sung Hwan Hong, Joong Mo Ahn
SJR Q1American Journal of Roentgenology

<b>OBJECTIVE.</b> The objective of our study was to compare the sensitivity of a deep learning (DL) algorithm with the assessments by radiologists in diagnosing osteonecrosis of the femoral head (ONFH) using digital radiography. <b>MATERIALS AND METHODS.</b> We performed a two-center, retrospective, noninferiority study of consecutive patients (≥ 16 years old) with a diagnosis of ONFH based on MR images. We investigated the following four datasets of unilaterally cropped hip anteroposterior radi

Orthopedics and Sports MedicineMedicine
10
Article|47 citations·2001
CASE REPORT: Ovarian Hyperstimulation Syndrome Complicating a Spontaneous Singleton Pregnancy: A Case Report
Hee‐Dong Chae, Eun-Joo Park, Sung-Hoon Kim, Chung‐Hoon Kim, Byung-Moon Kang, Yoon‐Seok Chang
SJR Q1Journal of Assisted Reproduction and Genetics
Reproductive MedicineMedicine
11
Article|23 citations·2006
Influence of Antiphospholipid Antibodies on Pregnancy Outcome in Women Undergoing In Vitro Fertilization and Embryo Transfer
Sa‐Ra Lee, Eun‐Joo Park, Sung‐Hoon Kim, Hee‐Dong Chae, Chung‐Hoon Kim, Byung‐Moon Kang
SJR Q2American Journal of Reproductive ImmunologyOA

PROBLEM: Antiphospholipid antibodies (APA) are thought to be involved in recurrent pregnancy loss. Therefore, we investigated the impact of APA on pregnancy outcome in women undergoing in vitro fertilization and embryo transfer (IVF-ET). METHOD OF STUDY: Blood samples taken from 54 Korean women referred for IVF were tested for the presence of APA, anticardiolipin antibody IgG and IgM and lupus anticoagulant. The standard gonadotropin-releasing hormone agonist long protocol was used for ovarian s

RheumatologyMedicine
12
Article|19 citations·2020
Combined use of virtual monochromatic images and projection-based metal artifact reduction methods in evaluation of total knee arthroplasty
Hee‐Dong Chae, Sung Hwan Hong, Mack Shin, Ja Young Choi, Hye Jin Yoo
SJR Q1European Radiology
Biomedical EngineeringEngineering
13
Article|17 citations·2009
Effects of pioglitazone on ovarian stromal blood flow, ovarian stimulation, and in vitro fertilization outcome in patients with polycystic ovary syndrome
Chung‐Hoon Kim, Gyun‐Ho Jeon, So-Ra Kim, So-Ra Kim, Hee‐Dong Chae, Byung‐Moon Kang, Hee‐Dong Chae, Byung‐Moon Kang
SJR Q1Fertility and SterilityOA
Reproductive MedicineMedicine
14
Article|12 citations·2010
A Comparative Study of Outside-In and Inside-Out Transobturator Tape Procedures for Stress Urinary Incontinence
Hee‐Dong Chae, So-Ra Kim, Gun-Ho Jeon, Dae‐Yeon Kim, Sung-Hoon Kim, Jong-Hyeok Kim, Chung-Hoon Kim, Yong‐Man Kim, Young‐Tak Kim, Byung‐Moon Kang, Joo‐Hyun Nam
SJR Q2Gynecologic and Obstetric Investigation

AIMS: This study compared the clinical outcome of patients undergoing outside-in transobturator tape (TOT) or inside-out transobturator tape (TVT-O) procedures for female stress urinary incontinence (SUI). METHODS: The study examined the medical records of 615 patients who underwent TOT (376 patients) or TVT-O (239 patients) for SUI, and compared patient characteristics, operation time, duration of hospital stay, cure rates, and complication rates, by conducting a 1-year follow-up survey. RESULT

RheumatologyMedicine
15
Article|12 citations·2017
Photoacoustic Imaging for Differential Diagnosis of Benign Polyps versus Malignant Polyps of the Gallbladder: A Preliminary Study
Hee‐Dong Chae, Jae Young Lee, Jin‐Young Jang, Jin Ho Chang, Jeeun Kang, Mee Joo Kang, Joon Koo Han
SJR Q1Korean Journal of RadiologyOA

These preliminary results indicate that benign versus malignant gallbladder polyps might exhibit different spectral patterns on multispectral PA imaging.

Biomedical EngineeringEngineering

Research Areas

Reproductive MedicineSurgeryObstetrics and GynecologyRheumatologyBiomedical EngineeringRadiology, Nuclear Medicine and Imaging

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