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Heon Gil Lim

Hanyang University · Medicine

About the Lab

Professor Heon Gil Lim's research lab focuses on cardiovascular and metabolic health, with a strong emphasis on the interplay between arterial stiffness, blood pressure variability, and target organ damage in hypertension and diabetes. The lab investigates biomarkers and clinical parameters—such as the Augmentation Index (AASI), bone mineral density (BMD), and left ventricular mass—across diverse populations to improve risk prediction and understanding of cardiovascular outcomes. Key research directions include the pathophysiology of diabetic cardiomyopathy, the impact of chronic diseases on health-related quality of life, and the role of systemic factors in vascular and cardiac remodeling.

arterial stiffnessblood pressure variabilitydiabetic cardiomyopathybone mineral densityleft ventricular mass

Research Overview

Papers
88
Total Citations
343
Papers (5y)
22
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
22total
2009
2010
2011
2012
2014
Citations per year (5y)
223total
20092010201120122014

Selected Papers

15
1
Article|34 citations·2011
The Relationship Between Ambulatory Arterial Stiffness Index and Blood Pressure Variability in Hypertensive Patients
Hyung Tak Lee, Young‐Hyo Lim, Bae Keun Kim, Kang Won Lee, Jae Ung Lee, Kyung Soo Kim, Soon Gil Kim, Jeong Hyun Kim, Heon Kil Lim, Jinho Shin, Yu‐Mi Kim
SJR Q2Korean Circulation JournalOA

AASI is closely correlated with BP variability. The result of this study shows that AASI is not only a parameter for arterial stiffness, but also a parameter for BP variability.

Cardiology and Cardiovascular MedicineMedicine
2
Article|27 citations·2011
Effects of granulocyte-colony stimulating factor (G-CSF) on diabetic cardiomyopathy in Otsuka Long-Evans Tokushima Fatty rats
Young‐Hyo Lim, Jun-Ho Joe, Ki-Seok Jang, Yi-Sun Song, Byung-Im So, Cheng-Hu Fang, Jinho Shin, Jung‐Hyun Kim, Heon‐Kil Lim, Kyung-Soo Kim
SJR Q1Cardiovascular DiabetologyOA

BACKGROUND: Diabetic cardiomyopathy (CMP) is a common and disabling disease in diabetic patients, however no effective treatments have been developed. Although granulocyte-colony stimulating factor (G-CSF) improves heart function in myocardial infarction, its effect on non-ischemic CMP such as diabetic CMP is unknown. In the present study, we investigated the effects of G-CSF on diabetic CMP in a rat model of type II diabetes. METHODS: Twenty 7-week-old male Otsuka Long-Evans Tokushima Fatty (OL

Cardiology and Cardiovascular MedicineMedicine
3
Article|23 citations·2014
The relationship between bone mineral density and blood pressure in the Korean elderly population: the Korea National Health and Nutrition Examination Survey, 2008–2011
Hyung Tak Lee, Jinho Shin, Seung Yeon Min, Young‐Hyo Lim, Kyung‐Soo Kim, Soon Gil Kim, Jeong Hyun Kim, Heon Kil Lim
SJR Q2Clinical and Experimental Hypertension

It is not clear whether the inverse relationship between bone mineral density (BMD) and blood pressure (BP) could be generalizable to the general elderly population. We used data from the fourth and fifth Korea National Health and Nutrition Examination Survey. The study sample consisted of 8439 men and postmenopausal women aged 50 years and older. We evaluated the relationship between BMD and BP. When adjusted for covariates, femur neck T-score [coefficient = -0.391, 95% confidence interval (CI)

Orthopedics and Sports MedicineMedicine
4
Article|23 citations·2014
Health-Related Quality of Life in Coronary Heart Disease in Korea
Hyung Tak Lee, Jinho Shin, Young‐Hyo Lim, Kyung Soo Kim, Soon Gil Kim, Jeong Hyun Kim, Heon Kil Lim
SJR Q2Angiology

Using data from 2007 to 2011 of the Korea National Health and Nutrition Examination Survey, we evaluated the influence of coronary heart disease (CHD) on health-related quality of life (HRQoL) as measured by the EQ-5D in comparison with the general population and the predictors of HRQoL in CHD. Compared with the general population, HRQoL was impaired in the EQ-5D dimensions of mobility, usual activities, pain/discomfort, and anxiety/depression. The impairment of HRQoL was much greater in the old

Economics and EconometricsEconomics, Econometrics and Finance
5
Article|21 citations·2011
Non-Dipper Pattern is a Determinant of the Inappropriateness of Left Ventricular Mass in Essential Hypertensive Patients
Bae Keun Kim, Young‐Hyo Lim, Hyung Tak Lee, Jae Ung Lee, Kyung Soo Kim, Soon Gil Kim, Jeong Hyun Kim, Heon Kil Lim, Jinho Shin
SJR Q2Korean Circulation JournalOA

BACKGROUND AND OBJECTIVES: Inappropriately high left ventricular mass (iLVM) is known to be related to cardiovascular prognosis. A non-dipper pattern has a greater mean left ventricular (LV) mass than the dipper pattern in hypertensive patients. However, the appropriateness of LV mass in dipper or non-dipper patterns has not been adequately investigated. The aim of this study was to define the relationship between nocturnal dipping and the appropriateness of LV mass. SUBJECTS AND METHODS: Using

Cardiology and Cardiovascular MedicineMedicine
6
Article|16 citations·2014
Relationship between bone mineral density and a 10-year risk for coronary artery disease in a healthy Korean population
Hyung Tak Lee, Jinho Shin, Seung Yeon Min, Young‐Hyo Lim, Kyung Soo Kim, Soon Gil Kim, Jeong Hyun Kim, Heon Kil Lim
SJR Q3Coronary Artery Disease

BMD was correlated inversely with the 10-year risk for CHD in the healthy male population. This result suggests that in the male population, measurement of BMD could be useful for prediction of the risk of CHD.

Orthopedics and Sports MedicineMedicine
7
Article|14 citations·2011
The Relationship Between Ambulatory Arterial Stiffness Index and Blood Pressure Variability in Hypertensive Patients
이형택, 임영효, 김배근, 이강원, 이재웅, 김경수, 김순길, 김종현, 임헌길, 신진호, 김유미

Background and Objectives: Ambulatory arterial stiffness index (AASI) is well known as a predictor of cardiovascular mor-tality in hypertensive patients. Mathematically, AASI reflect the standard deviation (SD) of blood pressure (BP) variation. AASI is measured higher levels in non-dipper than dipper. Thus, AASI has a possibility of not only reflecting arterial stiffness but also BP variability and/or autonomic nervous dysfunction. Subjects and Methods: Consecutive data from 418 untreated hypert

8
Article|13 citations·2011
Non-Dipper Pattern is a Determinant of the Inappropriateness of Left Ventricular Mass in Essential Hypertensive Patients
김배근, 임영효, 이형택, 이재웅, 김경수, 김순길, 김정현, 임헌길, 신진호

Background and Objectives: Inappropriately high left ventricular mass (iLVM) is known to be related to cardiovascular prognosis. A Non-dipper pattern has a greater mean left ventricular (LV) mass than the dipper pattern in hypertensive patients. However, the appropriateness of LV mass in dipper or non-dipper patterns has not been adequately investigated. The aim of this study was to define the relationship between nocturnal dipping and the appropriateness of LV mass. Subjects and Methods: Using

9
Article|11 citations·2007
Influence of abdominal circumference on the inappropriateness of left ventricular mass and diastolic function in non-obese patients.
Jinho Shin, Jae Ung Lee, Kyung Soo Kim, Soon Gil Kim, Jeong‐Hyun Kim, Heon Kil Lim, Bang Hun Lee
PubMed

BACKGROUND AND OBJECTIVE: Adipose tissue may be one of the sources of the humoral factors increasing left ventricular mass (LVM) via non-hemodynamic mechanisms. The involvement of visceral obesity in excessive or inappropriate LVM has not been established. We investigated the effect of abdominal circumference on the inappropriateness of LVM in non-obese patients. METHODS: Echocardiographic parameters for LVM and the indices for diastolic function were analyzed in 312 non-obese patients. Inapprop

Cardiology and Cardiovascular MedicineMedicine
10
Article|11 citations·2010
Development of acute myocardial infarction in a young female patient with essential thrombocythemia treated with anagrelide: a case report
Young‐Hyo Lim, Young Yiul Lee, Jae‐Hoon Kim, Jinho Shin, Jae Ung Lee, Kyung-Soo Kim, Soon-Kil Kim, Jeong Hyun Kim, Heon Kil Lim
The Korean Journal of HematologyOA

Essential thrombocythemia (ET) is a chronic myeloproliferative disorder with a prolonged clinical course. Since this disorder is considered to be at increased risk of thromboembolism, therapy is mainly focused on the decreased risk of thrombohemorrhagic events by use of cytotoxic agents. Anagrelide is a phosphodiesterase III inhibitor which is utilized in the treatment of ET for the reduction of platelets. However, patients treated with anagrelide might experience cardiovascular adverse effects

GeneticsMedicine
11
Article|11 citations·2009
Association Between Inappropriateness of Left Ventricular Mass and Left Ventricular Diastolic Dysfunction: A Study Using the Tissue Doppler Parameter, E/E'
Young Hyo Lim, Jae Ung Lee, Kyung Soo Kim, Soon Gil Kim, Jeong Hyun Kim, Heon Kil Lim, Bang Hun Lee, Jinho Shin
SJR Q2Korean Circulation JournalOA

BACKGROUND AND OBJECTIVES: The structural significance of the inappropriateness of left ventricular mass (iLVM) is known to be an important prognostic factor for cardiovascular events; however, the functional changes associated with iLVM have not been established. This study was performed to determine if diastolic dysfunction is associated with iLVM using a tissue Doppler technique. SUBJECTS AND METHODS: Three hundred sixty consecutive subjects, including 221 hypertension patients from the echoc

Cardiology and Cardiovascular MedicineMedicine
12
Article|10 citations·2000
Changes in Gallbladder Motility in Gastrectomized Patients
Joon Soo Hahm, Joon Yong Park, Yun Ju Cho, Chang Soo Eun, Yong Wook Lee, Ho Soon Choi, Byoeng Chul Yoon, Min Ho Lee, Choon Suhk Kee, Kyung Nam Park, Heon Kil Lim, Sung Joon Kwon
SJR Q2The Korean Journal of Internal MedicineOA

OBJECTIVES: Gastric resection may predispose gallstone formation. However, the mechanism has not been clearly understood. To evaluate the relationship between gastric resection and gallstone formation, we compared gallbladder(GB) motility in gastrectomized patients and control subjects. METHODS: We compared the GB volume and ejection fraction of the 46 gastrectomized patients with 37 healthy controls using real time ultrasonography. RESULTS: GB volume increased significantly in the gastrectomize

Pulmonary and Respiratory MedicineMedicine
13
Article|10 citations·1995
PR Interval Behavior During Exercise Stress Test
Jae Ung Lee, Kyung Soo Kim, Jeong Hyun Kim, Heon Kil Lim, Bang Hun Lee, Chung Kyun Lee
SJR Q2The Korean Journal of Internal MedicineOA

OBJECTIVES: The PR interval on the electrocardiogram represents conduction time from the onset of atrial activation through His-Purkinje conduction system during a normal cardiac cycle. While its behavior at rest and during exposure to various cardioactive drugs is well documented, there exist few reports which describe PR interval variations during exercise in normal control and patient groups. In the present study, we examined the behavior of the PR intervals during various stages of exercise,

Cardiology and Cardiovascular MedicineMedicine
14
Article|10 citations·2010
Bone Mineral Density is an Independent Determinant of Left Ventricular Mass Index in the General Female Population
Young‐Hyo Lim, Jinho Shin, Jae Ung Lee, Heon Kil Lim, Sangmo Hong, Mi Kyung Kim, Bo Youl Choi, Yu‐Mi Kim
SJR Q2Korean Circulation JournalOA

BMD is a consistent and independent determining factor of LVMI, BMI and carotid IMT in postmenopausal women.

Orthopedics and Sports MedicineMedicine
15
Review|9 citations·1998
A Case of Arteriovenous Type Cardiac Hemangioma
Kyung Jin Lee, Jinho Shin, Jung‐Hye Choi, Jai Lee, Tae Young Kim, Jae Ung Lee, Kyung Soo Kim, Soon Kil Kim, Jeong Hyun Kim, Heon Kil Lim, Bang Hun Lee, Chung Kyun Lee
SJR Q2The Korean Journal of Internal MedicineOA

Cardiac hemangiomas are rare primary tumors of the heart and constitute only 2.8% of primary cardiac tumors. They are classified into capillary, cavernous, epitheloid and arteriovenous type and the last one is the most uncommon type. We experienced a case of cardiac hemangioma which was diagnosed as arteriovenous type for the first time in Korea in the literature. The patient was a 54-year-old woman who presented with palpitation and anterior chest pain. The diagnosis was based upon coronary ang

Cardiology and Cardiovascular MedicineMedicine

Research Areas

Cardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineRadiology, Nuclear Medicine and ImagingOrthopedics and Sports MedicineGeneticsEpidemiology

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