Hong, Jun Young
Yonsei University · Immunology and Microbiology
About the Lab
Professor Hong, Jun Young's research lab specializes in human leukocyte antigen (HLA) genetics, with a focus on identifying and characterizing rare HLA alleles through high-resolution molecular analysis. The lab investigates the genetic variations—particularly single nucleotide polymorphisms (SNPs) at specific codons—that distinguish HLA alleles, contributing to immunogenetic diversity and its implications in disease susceptibility, transplantation, and autoimmune disorders. Their work bridges molecular genetics and clinical immunology, advancing precision medicine in transplantation and immune-related diseases.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
9Early-life environmental factors can have persistent effects on physiological functions by altering developmental procedures in various organisms. Recent experimental and epidemiological studies now further support the idea that developmental programming is also present in mammals, including humans, influencing long-term health. Although the mechanism of programming is still largely under investigation, the role of endocrine glucocorticoids in developmental programming is gaining interest. Studi
The HLA-DQA1*03:02:03 allele differs from HLA-DQA1*03:02:01:01 allele by a single nucleotide in codon 42.
The HLA-DRB4*01:162N allele differs from HLA-DRB4*01:03:01:01 allele by a single nucleotide in codon 131.
The HLA-A*26:01:75 allele differs from HLA-A*26:01:01:01 allele by a single nucleotide in codon -10.3.
The HLA-DQA1*01:03:07 allele differs from HLA-DQA1*01:03:01:01 allele by a single nucleotide in codon -8.
The HLA-C*01:242 allele differs from HLA-C*01:02:01:01 allele by a single nucleotide in codon 281.
The HLA-B*56:01:18 allele differs from HLA-B*56:01:01:01 allele by a single nucleotide in codon 326.3.
The HLA-DPA1*02:112 allele differs from the HLA-DPA1*02:02:02:01 allele by a single nucleotide at codon 29 in exon 2.
The HLA-C*08:01:36 allele differs from HLA-C*08:01:01:01 allele by a single nucleotide at position 42 G > C in exon 1.
Research Areas
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