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Hwan Jun Jae

Seoul National University · Medicine

About the Lab

Professor Hwan Jun Jae's research lab specializes in interventional radiology and image-guided interventions, with a primary focus on transcatheter arterial embolization (TAE) for various vascular and oncologic conditions. The lab investigates the clinical efficacy and safety of embolic agents—particularly N-Butyl Cyanoacrylate (NBCA)—in treating nonvariceal upper gastrointestinal bleeding and explores advanced imaging techniques like perfusion CT for early response assessment after transarterial chemoembolization (TACE). The lab also addresses challenges in embolic procedures by developing safer, biocompatible liquid embolic agents and improving interventional techniques to minimize complications such as catheter entrapment. Their work bridges interventional radiology, medical imaging, and interventional oncology to enhance patient outcomes in vascular and malignant diseases.

transcatheter embolizationN-Butyl Cyanoacrylateperfusion CTinterventional oncologyembolic agents

Research Overview

Papers
220
Total Citations
5,139
Papers (5y)
18
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
18total
2021
2022
2024
2025
2026
Citations per year (5y)
128total
20212022202420252026

Selected Papers

15
1
Article|128 citations·2013
Safety and Efficacy of Transcatheter Arterial Embolization for Lower Gastrointestinal Bleeding: A Single-center Experience with 112 Patients
Saebeom Hur, Hwan Jun Jae, Myungsu Lee, Hyo‐Cheol Kim, Jin Wook Chung
SJR Q2Journal of Vascular and Interventional Radiology
GastroenterologyMedicine
2
Article|110 citations·2007
Transcatheter Arterial Embolization of Nonvariceal Upper Gastrointestinal Bleeding with N-Butyl Cyanoacrylate
Hwan Jun Jae, Jin Wook Chung, Ah Young Jung, Whal Lee, Jae Hyung Park
SJR Q1Korean Journal of RadiologyOA

OBJECTIVE: To evaluate the clinical efficacy and safety of transcatheter arterial embolization (TAE) with N-Butyl Cyanoacrylate (NBCA) for nonvariceal upper gastrointestinal bleeding. MATERIALS AND METHODS: Between March 1999 and December 2002, TAE for nonvariceal upper gastrointestinal bleeding was performed in 93 patients. The endoscopic approach had failed or was discarded as an approach for control of bleeding in all study patients. Among the 93 patients NBCA was used as the primary embolic

GastroenterologyMedicine
3
Article|58 citations·2007
Transcatheter Arterial Embolization of Nonvariceal Upper Gastrointestinal Bleeding with N-Butyl Cyanoacrylate
제환준, 정진욱, 정아영, 이활, 박재형

Objective: To evaluate the clinical efficacy and safety of transcatheter arterial embolization (TAE) with N-Butyl Cyanoacrylate (NBCA) for nonvariceal upper gastrointestinal bleeding. Materials and Methods: Between March 1999 and December 2002, TAE for nonvariceal upper gastrointestinal bleeding was performed in 93 patients. The endoscopic approach had failed or was discarded as an approach for control of bleeding in all study patients. Among the 93 patients NBCA was used as the primary embolic

4
Article|56 citations·2010
The Role of Perfusion CT as a Follow-up Modality After Transcatheter Arterial Chemoembolization
Seung Hong Choi, Jin Wook Chung, Hyo‐Cheol Kim, Jin Baek, Chang Min Park, Suryoung Jun, Min Uk Kim, Eun Sun Lee, Hye Rim Cho, Hwan Jun Jae, Whal Lee, Jae Hyung Park
SJR Q1Investigative Radiology

We believe that perfusion CT is a feasible alternative modality for the successful early response assessment and early detection of a marginally recurred tumor after TACE. However, perfusion CT has limitations for the prediction of tumor recurrence after TACE.

Radiology, Nuclear Medicine and ImagingMedicine
5
Article|45 citations·2008
Experimental Study on Acute Ischemic Small Bowel Changes Induced by Superselective Embolization of Superior Mesenteric Artery Branches with N-Butyl Cyanoacrylate
Hwan Jun Jae, Jin Wook Chung, Hyo‐Cheol Kim, Young So, Hyung Guhn Lim, Whal Lee, Byoung Kwon Kim, Jae Hyung Park
SJR Q2Journal of Vascular and Interventional RadiologyOA
GastroenterologyMedicine
6
Article|42 citations·2016
pH-Sensitive sulfamethazine-based hydrogels as potential embolic agents for transcatheter vascular embolization
Quang Vinh Nguyễn, Myung Su Lee, Jae Seung Lym, Young Il Kim, Hwan Jun Jae, Doo Sung Lee
SJR Q1Journal of Materials Chemistry B

Vascular embolization is the intentional application of embolic agents to induce the occlusion of blood vessels that can be utilized to treat various diseases. Among currently available embolic agents, liquid types have received considerable interest for clinical use, recently. Popular liquid embolic agents such as the Onyx system and cyanoacrylate glue, although possess desirable advantages of quick occlusion and high penetration ability, still face some challenges in the utilization of toxic o

Molecular MedicineBiochemistry, Genetics and Molecular Biology
7
Article|40 citations·2009
The Antitumor Effect and Hepatotoxicity of a Hexokinase II Inhibitor 3-Bromopyruvate: In Vivo Investigation of Intraarterial Administration in a Rabbit VX2 Hepatoma Model
Hwan Jun Jae, Jin Wook Chung, Hee Sun Park, Min Jong Lee, Ki Chang Lee, Hyo‐Cheol Kim, Jung‐Hwan Yoon, Hesson Chung, Jae Hyung Park
SJR Q1Korean Journal of RadiologyOA

Even though intraarterial delivery of 3-BrPA shows a dose-related antitumor effect, single session treatment seems to have limited efficacy when compared with the conventional method.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
Article|32 citations·2017
Superselective Embolization for Arterial Upper Gastrointestinal Bleeding Using N -Butyl Cyanoacrylate: A Single-Center Experience in 152 Patients
Saebeom Hur, Hwan Jun Jae, Hyukjoon Lee, Myungsu Lee, Hyo‐Cheol Kim, Jin Wook Chung
SJR Q2Journal of Vascular and Interventional Radiology
GastroenterologyMedicine
9
Article|31 citations·2007
Chronic-Stage Deep Vein Thrombosis of the Lower Extremities
Eun‐Ah Park, Whal Lee, Min Woo Lee, Sang-Il Choi, Hwan Jun Jae, Jin Wook Chung, Jai Hyung Park
SJR Q3Journal of Computer Assisted Tomography

Luminal obliteration, decreased caliber, fibrotic bands, ipsilateral muscle enlargement, and superficial collateral vein development are common CT findings in chronic DVT of the lower extremity.

Internal MedicineMedicine
10
Article|29 citations·2007
Preoperative Evaluation of Lower Extremity Arteries for Free Fibula Transfer Using MDCT Angiography
Kwang Nam Jin, Whal Lee, Yong Yin, Sang-Il Choi, Hwan Jun Jae, Jin Wook Chung, Jae Hyung Park
SJR Q3Journal of Computer Assisted Tomography

Computed tomographic angiography is a reliable preoperative imaging technique for the selection of appropriate legs as candidates for fibular free transfer.

SurgeryMedicine
11
Article|28 citations·2011
Transcatheter Arterial Embolization of Intramuscular Active Hemorrhage with N-Butyl Cyanoacrylate
Dong Hyun Yoo, Hwan Jun Jae, Hyo‐Cheol Kim, Jin Wook Chung, Jae Hyung Park
SJR Q2CardioVascular and Interventional Radiology
SurgeryMedicine
12
Article|22 citations·2007
Follow-up CT Evaluation of the Mural Changes in Active Takayasu Arteritis
제환준, 박재형, 정진욱, 김효철, 이활, 소영호, 김상영

Objective: We wanted to evaluate the mural changes by CT on the follow-up examination of patients with active Takayasu arteritis. Materials and Methods: The study included 18 patients, (4 males and 14 females), with active Takayasu arteritis. A total of 44 CT examinations were done during the follow-up period (mean: 55.6 months). At the time of the last follow-up CT, the disease, on the basis of the erythrocyte sedimentation rate (ESR), was found to be inactive in five patients and the disease w

13
Article|17 citations·2014
Transcatheter Embolotherapy with N-Butyl Cyanoacrylate for Ectopic Varices
Jin Woo Choi, Hyo‐Cheol Kim, Hwan Jun Jae, Hyun-Seok Jung, Saebeom Hur, Myungsu Lee, Jin Wook Chung
SJR Q2CardioVascular and Interventional Radiology
HepatologyMedicine
14
Article|16 citations·2009
The Antitumor Effect and Hepatotoxicity of a Hexokinase II Inhibitor 3-Bromopyruvate: In Vivo Investigation of Intraarterial Administration in a Rabbit VX2 Hepatoma Model
제환준, 정진욱, 이민종, 김효철, 윤정환, 정혜선, 박재형, 이기창, 박희선

Objective: The purpose of this study was to compare the antitumor effect and hepatotoxicity of an intraarterial delivery of low-dose and high-dose 3-bromopyruvate (3-BrPA) and those of a conventional Lipiodol-doxorubicin emulsion in a rabbit VX2 hepatoma model. Materials and Methods: This experiment was approved by the animal care committee at our institution. VX2 carcinoma was implanted in the livers of 36 rabbits. Transcatheter intraarterial administration was performed using low dose 3- BrPA

15
Article|14 citations·2008
Cardiovascular Behcet Disease
Young Kwon Cho, Whal Lee, Sang Il Choi, Hwan Jun Jae, Jin Wook Chung, Jae Hyung Park
SJR Q3Journal of Computer Assisted Tomography

Unusual radiological manifestations of rare complications of cardiovascular Behcet disease (BD) are the following: (a) aneurysm and (b) occlusion in the aorta and its major branches, (c) pseudoaneurysms on the aortic root and coronary artery, and recurrent valvular dehiscence in the heart, (d) venous thrombosis in the deep and superficial venous system and vena cava. The initial exact diagnosis of cardiovascular BD has been extremely difficult for these rare complicated findings, especially in t

OphthalmologyMedicine

Research Areas

HepatologySurgeryPulmonary and Respiratory MedicineInternal MedicineGastroenterologyGenetics

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