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Hye Jung Cho

Yonsei University · Medicine

About the Lab

Professor Hye Jung Cho's research lab focuses on advancing minimally invasive surgical techniques and improving patient outcomes in critical care settings. The lab investigates innovative applications of robotic surgery—particularly DaVinci® single-port platforms—to enhance surgical precision, reduce recovery time, and improve cosmetic results. Additionally, the lab explores infection prevention strategies in high-risk populations, such as neonates and pediatric patients, with a focus on central line-associated bloodstream infections and Clostridium difficile-associated disease. The integration of engineering solutions in medical devices, such as micromachined PCR chips for rapid diagnostics, further highlights the lab’s interdisciplinary approach to improving clinical care.

single-port surgeryneonatal infectionClostridium difficilerobotic surgerythermal cycling in microfluidics

Research Overview

Papers
23
Total Citations
80
Papers (5y)
21
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
21total
2020
2021
2022
2023
2024
Citations per year (5y)
78total
20202021202220232024

Selected Papers

15
1
Article|21 citations·2024
Early Single-Center Experience of DaVinci® Single-Port (SP) Robotic Surgery in Colorectal Patients
Hye Jung Cho, Woo Ram Kim
SJR Q1Journal of Clinical MedicineOA

Background: DaVinci® single-port (SP) robotic surgery offers several benefits compared to traditional multiport laparoscopic or robotic surgeries. One of the main advantages is that it allows for a minimally invasive approach, resulting in a single, smaller incision and reduced trauma to the patient’s body, leading to less postoperative pain, faster recovery, and reduced risk of complications. The cosmesis of a single port with minimal visible scarring is also an attractive aspect to the patient

SurgeryMedicine
2
Article|10 citations·2021
Colonic Perforation After Treatment With Nivolumab in Esophageal Cancer: A Case Report
Hye Jung Cho, Woo Ram Kim, Joo-Hang Kim, Duk Hwan Kim, Dae Jung Kim, Haeyoun Kang
SJR Q2Annals of ColoproctologyOA

With the advent of checkpoint inhibitors, it has opened up opportunities for numerous cancer patients. However, as is the case with every treatment, complications need to be weighed. Gastrointestinal adverse effects, such as diarrhea and colitis are well-known complications for checkpoint inhibitors. In severe cases, colitis-induced colonic perforation may occur with an estimation of 1.0% to 1.5% in anti-CTLA-4 antibodies. However, only a handful of cases of such devastating complications have b

OncologyMedicine
3
Preprint|7 citations·2024
Early Single Center Experience of DaVinci<sup>®</sup> Single-Port (SP) Robotic Surgery in Colorectal Patients
Hye Jung Cho, Woo Ram Kim
Preprints.orgOA

Background DaVinci Single-Port (SP) robotic surgery offers several benefits compared to traditional multiport laparoscopic or robotic surgeries. One of the main advantages is that it allows for a minimally invasive approach, resulting in a single, smaller incision and reduced trauma to the patient’s body leading to less postoperative pain, faster recovery, and reduced risk of complications. The cosmesis of a single port with minimal visible scarring is also an attractive aspect to the patients;

SurgeryMedicine
4
Article|6 citations·2021
A comparative study between open versus laparoscopic Hartmann reversal
Hye Jung Cho, Woo Ram Kim, Jong Woo Kim
SJR Q3MedicineOA

ABSTRACT: As one of the most challenging procedures in colorectal surgery, Hartmann reversal (HR) carries a burden of morbidity and mortality. We report our experience and compare open and laparoscopic HR.Between December 2012 and January 2020, 30 patients who underwent Hartmann reversal were reviewed. All patients either received laparoscopic or open reversal.Of the 87 patients who underwent Hartmann operation (HO), 30 patients received HR (Laparoscopic Hartmann Reversal, [LHR], n = 20; Open Ha

SurgeryMedicine
5
Article|6 citations·2022
Prognostic significance of three endothelial nitric oxide synthase (eNOS) polymorphisms and metabolic syndrome (MetS) in patients with colorectal cancer
Eun Ju Ko, Eo Jin Kim, Hye Jung Cho, Jisu Oh, Han Sung Park, Chang Soo Ryu, Jung Oh Kim, Hak Hoon Jun, So Young Chong, Jong Woo Kim, Nam Keun Kim
SJR Q3Genes & GenomicsOA
PhysiologyMedicine
6
Article|5 citations·2024
Varying clinical relevance of sarcopenia and myosteatosis according to age among patients with postoperative colorectal cancer
Hye Jung Cho, Hye Sun Lee, Jeonghyun Kang
SJR Q1The journal of nutrition health & agingOA

Different age groups exhibited significantly variable skeletal muscle indices. Although an abundance of irrefutable results demonstrated a correlation between CT-defined sarcopenia, myosteatosis, and clinical prognosis, data regarding age-dependent correlations are scarce. Results of this study demonstrated that sarcopenia and myosteatosis did not influence the prognosis of young patients with postoperative CRC (≤50 years of age), inferring the existence of significantly different skeletal muscl

PhysiologyMedicine
7
Article|4 citations·2023
Genetic variants of MUC4 are associated with susceptibility to and mortality of colorectal cancer and exhibit synergistic effects with LDL-C levels
Min Kwon, Jeong Yong Lee, Eo Jin Kim, Eun Ju Ko, Chang Soo Ryu, Hye Jung Cho, Hak Hoon Jun, Jong Woo Kim, Nam Keun Kim
SJR Q1PLoS ONEOA

As a disease with high mortality and prevalence rates worldwide, colorectal cancer (CRC) has been thoroughly investigated. Mucins are involved in the induction of CRC and the regulation of intestinal homeostasis but a member of the mucin gene family MUC4 has a controversial role in CRC. MUC4 has been associated with either decreased susceptibility to or a worse prognosis of CRC. In our study, the multifunctional aspects of MUC4 were elucidated by genetic polymorphism analysis in a case-control s

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|4 citations·2024
Synergistic prognostic impact of hemoglobin and skeletal muscle index in patients with colorectal cancer
Hye Jung Cho, Hye Sun Lee, Jeonghyun Kang
SJR Q2Clinical Nutrition ESPEN
PhysiologyMedicine
9
Review|4 citations·2024
Sarcopenia diagnosis in patients with colorectal cancer: a review of computed tomography-based assessments and emerging ways to enhance practicality
Hye Jung Cho, Jeonghyun Kang
SJR Q2Annals of Surgical Treatment and ResearchOA

Traditionally, cancer treatment has focused on the stages of the disease; however, recent studies have highlighted the importance of considering the overall health status of patients in the prognosis of cancer. Loss of skeletal muscle, known as sarcopenia, has been found to significantly affect outcomes in many different types of cancers, including colorectal cancer. In this review, we discuss the guidelines for diagnosing sarcopenia, with a specific focus on CT-based assessments. Many groups wo

PhysiologyMedicine
10
Article|3 citations·2020
Robotic limited local resection of duodenal juxta‐ampullary neoplasms
Hye Jung Cho, Jae Young Jang, Sung Yub Jeong, Incheon Kang, Sung Hwan Lee, Sung Hoon Choi
SJR Q2International Journal of Medical Robotics and Computer Assisted Surgery

BACKGROUND: The unique and complex anatomical location of duodenal juxta-ampullary neoplasms complicates selection of the appropriate surgical strategy. For benign or borderline tumours, surgical local resection can be an appropriate treatment option, and robotic surgical systems can help perform minimally invasive local resection of these lesions. METHODS: Between December 2014 and December 2019, 10 patients who underwent robotic local resections for duodenal juxta-ampullary tumours were review

GastroenterologyMedicine
11
Article|3 citations·2020
Easily Applicable Single-incision Laparoscopic Appendectomy Using Straightforward Instrumental Alignment and Conventional Laparoscopic Instruments
Eui Hyuk Chong, Hye Jung Cho, Sung Yub Jeong, Woo Ram Kim, Sung Hoon Choi
SJR Q2Surgical Laparoscopy Endoscopy & Percutaneous Techniques

BACKGROUND: Laparoscopic appendectomy is one of the most frequently performed operations. As such, single-incision laparoscopic appendectomy (SILA) is indicated as a feasible and safe procedure comparable to conventional laparoscopic appendectomy (CLA). However, novice surgeons face challenges in performing SILA, because the role of the surgeon's hands is reversed. We introduce an easily applicable technique of SILA by adapting the alignment of CLA. METHODS: A series of 61 consecutive patients u

SurgeryMedicine
12
Article|2 citations·2023
Is cytoreductive surgery and hyperthermic intraperitoneal chemotherapy still beneficial in patients with colorectal peritoneal metastasis who undergoing palliative chemotherapy?
Hye Jung Cho, Jong Woo Kim, Woo Ram Kim
SJR Q2Asian Journal of SurgeryOA

CRS and HIPEC could be a treatment option for a carefully selected CPM patients performed by experienced surgeons. Overall survival of 41.50 months in palliative group compared to 16.8 months from conventional systemic CTx supports CRS and HIPEC even in palliative patients.

SurgeryMedicine
13
Article|1 citations·2022
Recent Update on the Treatment of Colorectal Peritoneal Metastasis: A Surgical Perspective
Hye Jung Cho, Woo Ram Kim
Journal of Digestive Cancer ResearchOA

Pre-oxaliplatin era showed a median survival of 8.9 months in CPM patients, which doubled to 16.3 months after the introduction of oxaliplatin, irinotecan, and targeted agents, such as bevacizumab and cetuximab Five-year overall JDCR

SurgeryMedicine
14
Article|1 citations·2004
Regulations of Bicarbonate Ions in Hypokalemic Rat Kidney
Ji Hye Kim, Hye Jung Cho, Mi Ok Bae, Jeong-Jin Park, Kyu Youn Ahn
Daehan hae'bu haghoeji
NephrologyMedicine
15
letter|1 citations·2024
Oncological safety of laparoscopic surgery for low rectal cancer
Hye Jung Cho, Nam Kyu Kim
SJR Q1˜The œLancet. Gastroenterology & hepatology
OncologyMedicine

Research Areas

SurgeryOncologyPhysiologyMolecular BiologyClinical PsychologyGastroenterology

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