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Hyo-Cheol Kim

Seoul National University · Medicine

About the Lab

Professor Hyo-Cheol Kim's research lab specializes in interventional radiology and image-guided cancer therapies, with a primary focus on hepatocellular carcinoma (HCC) and gastrointestinal stromal tumors (GISTs). The lab investigates advanced embolic techniques such as transarterial chemoembolization (TACE) and yttrium-90 radioembolization (TARE), emphasizing optimization of drug delivery systems, imaging biomarkers, and treatment response evaluation. Key research directions include the characterization of extrahepatic collateral vessels, in-vitro and in-vivo pharmacokinetic studies of Lipiodol-based embolic agents, and the development of accurate radiological criteria for tumor diagnosis and treatment planning.

interventional radiologyhepatocellular carcinomatranscatheter embolizationgastrointestinal stromal tumorsimage-guided therapy

Research Overview

Papers
445
Total Citations
8,443
Papers (5y)
128
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
128total
2022
2023
2024
2025
2026
Citations per year (5y)
397total
20222023202420252026

Selected Papers

15
1
Article|243 citations·2005
Recognizing Extrahepatic Collateral Vessels That Supply Hepatocellular Carcinoma to Avoid Complications of Transcatheter Arterial Chemoembolization
Hyo‐Cheol Kim, Jin Wook Chung, Whal Lee, Hwan Jun Jae, Jae Hyung Park
SJR Q1Radiographics

Extrahepatic collateral arteries commonly supply hepatocellular carcinomas if the tumors are large or peripherally located. Because development of these vessels interferes with effective control of the tumor with transcatheter arterial chemoembolization (TACE), radiologists should become familiar with the imaging findings of extrahepatic collateral vessels to detect them at an early stage. The authors observed 2104 such vessels in 860 patients over 5.5 years. The extrahepatic collateral vessels

HepatologyMedicine
2
Article|111 citations·2004
Gastrointestinal Stromal Tumors of the Stomach: CT Findings and Prediction of Malignancy
Hyo‐Cheol Kim, Jeong Min Lee, Kyung Won Kim, Seong Ho Park, Se Hyung Kim, Jae‐Young Lee, Joon Koo Han, Byung Ihn Choi
SJR Q1American Journal of Roentgenology

Although presence of an ulcer, mesenteric fat infiltration, direct organ invasion, and metastasis were more frequently observed in tumors with a high mitotic rate, no CT feature, other than size, was found to have predictive value with respect to malignant gastrointestinal stromal tumors of the stomach.

GastroenterologyMedicine
3
Article|75 citations·2014
Comparison of Drug Release and Pharmacokinetics after Transarterial Chemoembolization Using Diverse Lipiodol Emulsions and Drug-Eluting Beads
Jin Woo Choi, Hyun‐Jong Cho, Ju-Hwan Park, Song Yi Baek, Jin Wook Chung, Dae‐Duk Kim, Hyo‐Cheol Kim
SJR Q1PLoS ONEOA

In many studies for chemoembolization of hepatocellular carcinoma, the Lipiodol emulsion preparation protocols, especially the mixing steps, were unclear or even unrevealed at all. However, doxorubicin (DOX) release may depend on the composition and volume ratio (Lipiodol to DOX solution) of a Lipiodol emulsion. Therefore, we conducted a preclinical study to compare in-vitro drug release and in-vivo pharmacokinetics of DOX from diverse Lipiodol emulsions and drug-eluting beads (DEBs) and to comp

HepatologyMedicine
4
Review|68 citations·2017
Radioembolization for the treatment of hepatocellular carcinoma
Hyo‐Cheol Kim
SJR Q1Clinical and Molecular HepatologyOA

Transarterial radioembolization (TARE) with yttrium 90 (<sup>90</sup>Y), an intra-arterial procedure performed by interventional radiologists, has begun being utilized in managing hepatocellular carcinoma (HCC) in Korea. There are two available TARE products: glass and resin microspheres with different physical characteristics. All patients undergoing TARE must be assessed with clinical examination and laboratory tests as well as a thorough angiographic evaluation. TARE is safe and effective in

HepatologyMedicine
5
Article|68 citations·2003
Role of CT Venography in the Diagnosis and Treatment of Benign Thoracic Central Venous Obstruction
Hyo‐Cheol Kim, Jin Wook Chung, Jai Hyung Park, Yong Yin, Seong Ho Park, Chang Jin Yoon, Young Ho Choi
SJR Q1Korean Journal of RadiologyOA

The findings of CT venography correlated closely with those of digital subtraction venography, and the former accurately depicted the degree and extent of benign venous obstruction.

Emergency Medical ServicesHealth Professions
6
Article|63 citations·2004
Imaging of Gastrointestinal Stromal Tumors
Hyo‐Cheol Kim, Jeong Min Lee, Seung Hong Choi, Kyung Won Kim, Se Hyung Kim, Jae‐Young Lee, Joon Koo Han, Byung Ihn Choi
SJR Q3Journal of Computer Assisted Tomography

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract and are defined by their expression of KIT (CD117). This article includes 109 pathologically proven GISTs, with emphasis on their various computed tomography (CT) features. Although the images of GISTs on the CT scan are often distinct from those of epithelial tumors, radiologists should be familiar with these features for the accurate diagnosis of GISTs.

GastroenterologyMedicine
7
Article|62 citations·2011
Percutaneous Transsplenic Access to the Portal Vein for Management of Vascular Complication in Patients with Chronic Liver Disease
Hee Ho Chu, Hyo‐Cheol Kim, Hwan Jun Jae, Nam‐Joon Yi, Kwang‐Woong Lee, Kyung‐Suk Suh, Jin Wook Chung, Jae Hyung Park
SJR Q2CardioVascular and Interventional Radiology
HepatologyMedicine
8
Review|58 citations·2015
Role of C-Arm Cone-Beam CT in Chemoembolization for Hepatocellular Carcinoma
Hyo‐Cheol Kim
SJR Q1Korean Journal of RadiologyOA

With the advent of C-arm cone-beam computed tomography (CBCT), minimally-invasive procedures in the angiography suite made a new leap beyond the limitations of 2-dimensional (D) angiography alone. C-arm CBCT can help interventional radiologists in several ways with the treatment of hepatocellular carcinoma (HCC); visualization of small tumors and tumor-feeding arteries, identification of occult lesion and 3D configuration of tortuous hepatic arteries, assurance of completeness of chemoembolizati

HepatologyMedicine
9
Article|57 citations·2004
Primary Gastrointestinal Stromal Tumors in the Omentum and Mesentery: CT Findings and Pathologic Correlations
Hyo‐Cheol Kim, Jeong Min Lee, Se Hyung Kim, Kyung Won Kim, Lee Min-Jin, Young Jun Kim, Joon Koo Han, Byung Ihn Choi
SJR Q1American Journal of Roentgenology

On contrast-enhanced CT, primary gastrointestinal stromal tumors in the omentum and mesentery are usually well-defined, huge masses that contain large areas of low-attenuation necrosis and hemorrhage and that lack central gas.

GastroenterologyMedicine
10
Article|56 citations·2003
Primary thyroid lymphoma: CT findings
Hyo‐Cheol Kim, Moon Hee Han, Keon Ha Kim, Hwan Jun Jae, Sang‐Hyun Lee, Sam Soo Kim, Kwang Hyun Kim, K H Chang
SJR Q1European Journal of Radiology
Endocrinology, Diabetes and MetabolismMedicine
11
Article|56 citations·2010
The Role of Perfusion CT as a Follow-up Modality After Transcatheter Arterial Chemoembolization
Seung Hong Choi, Jin Wook Chung, Hyo‐Cheol Kim, Jin Baek, Chang Min Park, Suryoung Jun, Min Uk Kim, Eun Sun Lee, Hye Rim Cho, Hwan Jun Jae, Whal Lee, Jae Hyung Park
SJR Q1Investigative Radiology

We believe that perfusion CT is a feasible alternative modality for the successful early response assessment and early detection of a marginally recurred tumor after TACE. However, perfusion CT has limitations for the prediction of tumor recurrence after TACE.

Radiology, Nuclear Medicine and ImagingMedicine
12
Article|56 citations·2003
Afferent loop obstruction after gastric cancer surgery: helical CT findings
Hyo‐Cheol Kim, Joon Koo Han, Ki Woong Kim, Y. H. Kim, Han‐Kwang Yang, Seon Hahn Kim, Hyung Jin Won, Kyoung Ho Lee, Byung Ihn Choi
Abdominal Imaging
SurgeryMedicine
13
Article|52 citations·2002
Hepatic Arterial and Portal Venous Phase Helical CT in Patients Treated with Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Added Value of Unenhanced Images
Hyo‐Cheol Kim, Ahyoung Kim, Joon Koo Han, Jin Wook Chung, Jae Young Lee, Jae Hyung Park, Byung Ihn Choi
SJR Q1Radiology

The study data demonstrate the diagnostic value of unenhanced images interpreted in conjunction with biphasic CT images for follow-up of patients who have previously been treated with TACE for HCC.

HepatologyMedicine
14
Article|48 citations·2013
Transarterial Chemoembolization with Additional Cisplatin Infusion for Hepatocellular Carcinoma Invading the Hepatic Vein
Hyo‐Cheol Kim, Jeong‐Hoon Lee, Jin Wook Chung, Beomsik Kang, Jung‐Hwan Yoon, Yoon Jun Kim, Hyo-Suk Lee, Hwan Jun Jae, Jae Hyung Park
SJR Q2Journal of Vascular and Interventional Radiology
HepatologyMedicine
15
Article|48 citations·2007
Multiple-Electrode Radiofrequency Ablation of In Vivo Porcine Liver
Jeong Min Lee, Joon Koo Han, Hyo‐Cheol Kim, Se Hyung Kim, Kyung Won Kim, Seung Moon Joo, Byung Ihn Choi
SJR Q1Investigative Radiology

Multiple-electrode RF systems in switching monopolar and multipolar modes more efficiently created a larger, confluent, spherical-shaped coagulation than conventional consecutive RF ablation.

Biomedical EngineeringEngineering

Research Areas

HepatologySurgeryPulmonary and Respiratory MedicineGeneticsGastroenterologyRadiology, Nuclear Medicine and Imaging

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