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Hyun Jin Han

Yonsei University · Medicine

About the Lab

Professor Hyun Jin Han's research lab specializes in cerebrovascular diseases, with a primary focus on the diagnosis, treatment, and outcomes of intracranial aneurysms and brain metastases. The lab investigates endovascular and microsurgical interventions such as stent-assisted coiling, gamma knife radiosurgery, and microsurgical clipping, emphasizing patient outcomes, complication risks, and imaging-based assessment. Research also extends to acute neurovascular injuries, including penetrating neck trauma and intracerebral hemorrhage, particularly during public health challenges like the COVID-19 pandemic.

intracranial aneurysmsbrain metastasescerebrovascular interventionsstroke outcomesimaging-guided therapy

Research Overview

Papers
34
Total Citations
164
Papers (5y)
29
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
29total
2021
2022
2023
2024
2025
Citations per year (5y)
135total
20212022202320242025

Selected Papers

15
1
Article|22 citations·2021
Flow diverter for the treatment of large (> 10 mm) vertebral artery dissecting aneurysms
Woosung Lee, Hyun Jin Han, Junhyung Kim, Keun Young Park, Yong Bae Kim, Chang Ki Jang, Joonho Chung
SJR Q1Acta NeurochirurgicaOA
NeurologyMedicine
2
Article|20 citations·2021
Safety and Efficacy of Stent-Assisted Coiling of Unruptured Intracranial Aneurysms Using Low-Profile Stents in Small Parent Arteries
Junhyung Kim, Hyun Jin Han, Woosung Lee, Sang Kyu Park, Joonho Chung, Yong Bae Kim, Keun Young Park
SJR Q1American Journal of NeuroradiologyOA

Stent-assisted coiling of intracranial aneurysms with low-profile stents in small vessels (≤ 2.0 mm) had a 100% success rate and a 15.2% overall complication rate with 4.5% morbidity. Current smoking was a significant risk factor associated with procedure-related complications.

NeurologyMedicine
3
Article|17 citations·2023
Prediction of cerebral hemorrhagic transformation after thrombectomy using a deep learning of dual-energy CT
JoonNyung Heo, Youngno Yoon, Hyun Jin Han, Jung‐Jae Kim, Keun Young Park, Byung Moon Kim, Dong Joon Kim, Young Dae Kim, Hyo Suk Nam, Seung‐Koo Lee, Beomseok Sohn
SJR Q1European Radiology
EpidemiologyMedicine
4
Article|16 citations·2016
Optimal Treatment Decision for Brain Metastases of Unknown Primary Origin: The Role and Timing of Radiosurgery
Hyun Jin Han, Won Seok Chang, Hyun Ho Jung, Yong Gou Park, Hae Yu Kim, Jong Hee Chang
Brain Tumor Research and TreatmentOA

Identification of a primary tumor before GKRS did not affect the patient outcomes. If other possible differential diagnoses were completely excluded, early GKRS can be an effective treatment option for brain metastases from unknown primary tumor.

Pulmonary and Respiratory MedicineMedicine
5
Article|13 citations·2016
The Neck and Posterior Fossa Combined Penetrating Injury: A Case Report
Hyun Jin Han, Jun Ho Jung, Chang Ki Hong, Yong Bae Kim
SJR Q3Korean Journal of NeurotraumaOA

Here we report a case of penetrating neck injury to the posterior fossa that was shown, using high-resolution computed tomography (HRCT) and digital subtraction angiography (DSA), to involve no vascular injury. A 54-year-old man was brought to the emergency department after a penetrating injury to the left side of the posterior neck and occipital area with a knife. He was in an intoxicated state and could not communicate readily. On initial examination, his vital signs were stable and there was

OphthalmologyMedicine
6
Article|9 citations·2021
Formation, Growth, or Rupture of De Novo Intracranial Aneurysms: Long-Term Follow-up Study of Subarachnoid Hemorrhage Survivors
Hyun Jin Han, Woosung Lee, Junhyung Kim, Keun Young Park, Sang Kyu Park, Joonho Chung, Yong Bae Kim
SJR Q1NeurosurgeryOA

BACKGROUND: The survival rate of aneurysmal subarachnoid hemorrhage (aSAH) has gradually increased, leading to more clinical cases of de novo intracranial aneurysms (DNIAs). OBJECTIVE: To identify the characteristics of patients with DNIA growth or rupture. METHODS: We included 1601 patients with aSAH treated by clipping from January 1993 to May 2010. According to the inclusion and exclusion criteria, 233 patients had no DNIAs, and 63 patients had 77 DNIAs. We assessed the incidence rate of DNIA

NeurologyMedicine
7
Article|9 citations·2021
Delays in Intracerebral Hemorrhage Management Is Associated with Hematoma Expansion and Worse Outcomes: Changes in COVID-19 Era
Hyun Jin Han, Keun Young Park, Junhyung Kim, Woosung Lee, Yun Ho Lee, Chang Ki Jang, Kwang‐Chun Cho, Sang Kyu Park, Joonho Chung, Young Sub Kwon, Yong Bae Kim, Jae Whan Lee
SJR Q2Yonsei Medical JournalOA

During the COVID-19 era, delays in management of ICH was associated with hematoma expansion and worse outcomes.

NeurologyMedicine
8
Article|9 citations·2023
Endoscope-assisted microsurgical clipping and reduction of post-clipping cerebral infarction: historical comparison using diffusion-weighted images
Kang U. Kim, Jung‐Jae Kim, Keun Young Park, Yong Bae Kim, Hyun Jin Han
SJR Q1Neurosurgical Review
NeurologyMedicine
9
Article|8 citations·2022
Incidence rate and predictors of recurrent aneurysms after clipping: long-term follow-up study of survivors of subarachnoid hemorrhage
Hyun Jin Han, Woosung Lee, Junhyung Kim, Keun Young Park, Sang Kyu Park, Joonho Chung, Yong Bae Kim
SJR Q1Neurosurgical Review
NeurologyMedicine
10
Article|8 citations·2021
Predictors of Ventriculostomy-Associated Infections: A Retrospective Study of 243 Patients
Junhyung Kim, Jae Ho Kim, Woosung Lee, Hyun Jin Han, Keun Young Park, Joonho Chung, Yong Bae Kim, Jin Yang Joo, Sang Kyu Park
SJR Q2World NeurosurgeryOA
Cellular and Molecular NeuroscienceNeuroscience
11
Article|8 citations·2021
Ruptured Infundibular dilatation of the posterior communicating artery
Woosung Lee, Hyun Jin Han, Junhyung Kim, Jin‐Young Choi, Keun Young Park, Yong Bae Kim, Joonho Chung
SJR Q1Acta NeurochirurgicaOA
NeurologyMedicine
12
Article|4 citations·2024
Incidence and Characteristics of Cerebral Infarction After Microsurgical Clipping of Unruptured Anterior Circulation Cerebral Aneurysms: Diffusion-Weighted Imaging-Based Analysis of 600 Patients
Hyun Jin Han, Kyu Seon Chung, Solbi Kim, Jung‐Jae Kim, Keun Young Park, Yong Bae Kim
SJR Q1Neurosurgery

BACKGROUND AND OBJECTIVES: Postclipping cerebral infarction (PCI) remains a major concern after treatment for unruptured intracranial aneurysms (UIAs). However, studies of microsurgical clipping based on diffusion-weighted imaging are limited. We aimed to present the incidence, risk factors, and types of PCI and its radiological and clinical characteristics. METHODS: This was a retrospective single-center study in which patients were scheduled to undergo microsurgical clipping for anterior circu

NeurologyMedicine
13
Article|4 citations·2024
Real-world application of a 3D deep learning model for detecting and localizing cerebral microbleeds
So Yeon Won, Jun-Ho Kim, Changsoo Woo, Dong‐Hyun Kim, Keun Young Park, Eung Yeop Kim, Sun‐Young Baek, Hyun Jin Han, Beomseok Sohn
SJR Q1Acta Neurochirurgica
NeurologyMedicine
14
Article|4 citations·2023
Perioperative Low-Dose Aspirin Management for Planned Clipping Surgery: When, How Long, and With What Precautions?
Hyun Jin Han, Junhyung Kim, Chang Ki Jang, Jung‐Jae Kim, Keun Young Park, Sang Kyu Park, Joonho Chung, Yong Bae Kim
SJR Q1Neurosurgery

BACKGROUND AND OBJECTIVE: Perioperative low-dose aspirin (ASA) management for open craniotomy surgery lacked information. We analyze to establish the perioperative ASA strategy to minimize both hemorrhagic and thromboembolic complications. METHODS: The investigators designed a multicenter retrospective study, which included patients scheduled to have clipping surgery for unruptured intracranial aneurysm. The incidence and risk factors were analyzed for postoperative hemorrhagic complications and

Cardiology and Cardiovascular MedicineMedicine
15
Article|2 citations·2025
FloWise Flow Diverter for Treatment of Unruptured Wide-Neck Intracranial Aneurysms: A Prospective, Multicenter, Single-Arm, Open-Label, Pivotal Study
Hyun Jin Han, Keun Young Park, Byung Moon Kim, Yong Bae Kim, Hong Jun Jeon, Sang Hyun Suh, Sang‐il Suh, Jung‐Jae Kim, Jun-Hwee Kim, Chang Ki Jang, Dong Joon Kim, Jung Keun Lee
SJR Q1Korean Journal of RadiologyOA

FloWise flow diverter is safe and effective for the treatment of unruptured wide-neck aneurysms.

NeurologyMedicine

Research Areas

NeurologyPulmonary and Respiratory MedicineEpidemiologyCellular and Molecular NeuroscienceCardiology and Cardiovascular MedicineOphthalmology

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