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Hyun-Kyeom Park

Hanyang University · Medicine

About the Lab

Professor Hyun-Kyeom Park's research lab specializes in surgical oncology and advanced abdominal surgery, with a focus on rare and complex gastrointestinal malignancies, including hepatoid adenocarcinoma, acinar cell carcinoma of the pancreas, and gallbladder tumors. The lab investigates diagnostic challenges, surgical management, and prognostic factors in these rare neoplasms, often emphasizing the role of immunohistochemistry and imaging in accurate diagnosis. Additionally, the lab explores innovative surgical techniques and biomaterials for urological and hepato-biliary reconstruction, such as the use of bovine pericardium in bladder repair and surgical treatment of polycystic liver disease.

surgical oncologyrare gastrointestinal tumorsabdominal traumabladder reconstructionhepato-biliary surgery

Research Overview

Papers
13
Total Citations
14
Papers (5y)
11
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
11total
2003
2004
2010
2011
2013
Citations per year (5y)
14total
20032004201020112013

Selected Papers

13
1
Article|7 citations·2011
Hepatoid adenocarcinoma of the gallbladder with production of alpha-fetoprotein
이재훈, 이경근, 백승삼, 박훤겸, 이광수

Hepatoid adenocarcinoma (HAC) is a tumor with aberrant hepatocellular differentiation that occurs in extrahepatic organs. HAC of the gallbladder is rare, and cases of alpha-fetoprotein production are extremely rare. A 61-year-old man was diagnosed with gallbladder adenocarcinoma after laparoscopic cholecystectomy. A radical operation including resection of liver bed and lymph node dissection was performed, and no tumor cell was found. However, at postoperative 19 months, he showed lymphadenopath

2
Article|4 citations·2004
원발성 알도스테론증 12예의 임상적 고찰
조승철, 김순길, 최웅환, 안유헌, 정파종, 김태화, 박용수, 박훤겸, 이성희
3
Article|1 citations·2013
Massive umbilical variceal bleeding in alcoholic cirrhosis and its long‐term successful treatment by rubber band ligation
Tae Yeob Kim, Joo Hyun Sohn, Hyun Soo Kim, Hwon Gyeom Park
SJR Q2Journal of Digestive DiseasesOA
HepatologyMedicine
4
Article|1 citations·2003
S자결장 정맥류를 동반한 Klippel-Trenaunay-Weber 증후군 1예
정용우, 한동수, 백창희, 박윤경, 김종표, 이항락, 김진배, 손수현, 함준수, 박훤겸

결장 정맥류는 하부 위장관 출혈을 유발하는 매우 드문 질환으로 다양한 원인에 의해 발생한다. 일단 출혈이 발생하면 식도 정맥류 출혈보다 매우 치명적이다. Klippel-Trenaunay-Weber 증후군은 모세혈관기형, 심부 정맥류, 사지의 기형 등이 특징인 드문 질환이다. 저자는 전신과 안면에 혈관 확장, 대장 내시경검사에서 S자결장 정맥류가 있고, 상대 정맥과 하대 정맥이 동시에 폐쇄되었으며 신체 기형이 있는 Klippel-Trenaunay- Weber 증후군 환자에서 심한 정맥류 출혈로 S자결장 부분절제술을 시행한 예를 경험하였기에 문헌 고찰과 함께 보고한다.

5
Article|1 citations·2010
Acinar Cell Carcinoma of the Pancreas: A Report of Two Cases with Long-term Follow-up and a Review of the Literature
Jae Hoon Lee, 이경근, 오영하, 백승삼, 박훤겸, Kwang Soo Lee

Acinar cell carcinoma (ACC) of the pancreas is a rare malignancy making up approximately 1% of pancreatic non-endocrine malignant tumors. The common finding on computed tomography is a solitary, well-defined, heterogenous hypodense mass with enhancing capsule. ACC is a highly cellular tumor with minimal stroma and a lack of stromal desmoplasia. The accurate diagnosis of ACC cannot typically be done by histology alone but rather requires immunohistochemical staining or electron microscopy for the

6
Article|0 citations·2003
복부 자상에 의한 하대정맥 관통상
김지훈, 이홍기, 조석주, 박훤겸, 백홍규, 남영수

Injuries of the inferior vena cava (IVC) might be caused by a blunt trauma, which usually affects the retrohepatic portion. Injuries of the infrahepatic IVC are usually caused by penetrating injuries and rarely occur in Korea. We report a case of a penetrating injury of the IVC at the infrahepatic suprarenal portion with a review of other reported cases. (J Korean Surg Soc 2003;64:447-450)

7
Article|0 citations·2002
한국인 원발성 간세포암에서의 염색체 변화에 대한 연구
박훤겸
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0870420020060010012

Background/Aims: The pattern of chromosomal gains and losses in HCC with hepatitis B in Korean patients is very complex and involves virtually every site in the genome. This study was done to know the chromosomal aberrations in hepatocellular carcinoma with HBV and relationship between these lesions and previously known oncogenes and tumor suppressor genes. Methods: DNA changes in 23 hepatocellular carcinomas (HCC) associated with hepatitis B virus (HBV) were analyzed by CGH technique. Results:

8
Article|0 citations·2003
간세포암과 동반된 중복암의 임상병리학적 특징
최동호, 김한준, 이경근, 박훤겸, 권오정, 이광수

Purpose: Multiple primary cancers are not a rare disease. The clinicopathologic characteristics of a hepatocellular carcinoma with extrahepatic malignancies, have not been identified. To address these points, the clinical data of patients with a hepatocellular carcinoma, with extrahepatic malignancies, treated with surgical resections at our hospital, were retrospectively reviewed. Methods: We reviewed the clinical records of ten hepatocellular carcinoma patients, with extrahepatic malignancies,

9
Article|0 citations·2011
[Free Paper] When is the optimal time for laparoscopic cholecystectomy in gallbaldder empyema?
Yong Jin Kwon, Hwon Gyeom Park, Kwang Soo Lee, Kyeong Geun Lee
대한외과학회 학술대회 초록집
Pulmonary and Respiratory MedicineMedicine
10
Article|0 citations·2003
간의 원발성 평활근육종
최동호, 이경근, 김한준, 박훤겸, 권오정, 이광수

A primary hepatic sarcoma is a rare tumor, that most frequently arises from hepatic connective tissue or vascular channels, and is usually located in the intrahepatic area. Pedunculated, or bulging, lesions have also been reported. We encountered a pedunculated primary hepatic leiomyosarcoma occurring in a 61-year-old woman. A giant exophytic hepatic mass measuring 15x10cm in size, was located in the left lateral segment of the liver, which was compressing the stomach. A left lateral segmentecto

11
Article|0 citations·2011
Bladder Reconstruction Using Bovine Pericardium in a Case of Enterovesical Fistula
문성진, 김대희, 조정기, 정재훈, 이주용, 박성열, 김용태, 박훤겸, 최홍용, 문홍상
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0358320110520020150

The use of graft materials in bladder mucosa has been examined in animal models, but debate exists over which materials are effective. Intestine has been used as a substitute in augmentation cystoplasty for patients with neuropathic bladder, but serious adverse effects of the operation have occurred in some instances. We report a case of a successful repair of an enterovesical fistula by use of bovine pericardium. The patient has remained well for 2.5 years. We suggest that bovine pericardium ma

12
Article|0 citations·2010
한국의 췌장 선방 세포암- 국내 문헌 발표된 27예와 본원의 2예의 임상병리학적 고찰 -
이재훈, 이경근, 박훤겸, 이광수

목적: 췌장의 선방 세포암은 외분비선에서 발생하는 종양으로 1-2%를 차지하는 매우 드문 악성종양이다. 국내의 선방 세포암에 대한 연구는 미흡한 실정이다. 이번 연구는 국내에서 보고된 선방 세포암에 대해 임상양상, 병리학적 특징, 치료와 예후를 알아보고자 시작되었다. 대상 및 방법: 2009년 10월까지 국내에 보고된 논문을 검색하여 병리학적으로 췌장 선방 세포암으로 확인된 총 27예의 환자와 본원에서 경험한 2예를 포함하여 총 29예에 대해 임상양상, 방사선 소견, 면역조직염색검사를 포함한 병리학적 특징, 수술과 재발 유무, 보조요법과 생존여부를 조사하였다. 이와 함께 외국의 연구와 비교하여 국내 선방 세포암의 특징을 고찰하였다. 결과: 선방 세포암은 50대의 남자에서 호발하며, 증상으로는 복부 동통과 종괴가 흔하다. 췌장 미부(41.4%)의 발생 빈도가 높았으며, 크기도 평균 7 cm으로 큰 양상을 보였다. 진단 당시 간 전이가 흔하고, 술 후 재발은 대부분 18개월 이내에 발생

13
Article|0 citations·2002
단일엽에 국한된 다낭성 간질환에서의 수술적 치료
최동호, 이광수, 이경근, 김한준, 박훤겸, 권오정
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0371320020630020171

Adult polycystic liver disease (APLD) is an inherited, benign rare condition, often associated with polycystic kidney disease. Liver failure is unusual, but some patients may require therapy. Surgery appears to be more effective in relieving the symptoms of APLD for an extended period than nonsurgical therapies. We report on the successful surgical treatment of a case of APLD located in the left lobe of the liver. (J Korean Surg Soc 2002;63:171-174)

Research Areas

HepatologyPulmonary and Respiratory Medicine

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