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Hyunwoo Nam

Seoul National University · Medicine

About the Lab

Professor Hyunwoo Nam's research lab specializes in neurological and cerebrovascular disorders, with a focus on epilepsy, cerebral small vessel disease (SVD), and sleep apnea. The lab investigates the pathophysiological mechanisms linking epilepsy—particularly in temporal lobe epilepsy and focal cortical dysplasia with hippocampal sclerosis—to cerebrovascular dysfunction and neuroimaging biomarkers. Using advanced neurophysiological techniques such as ICA-based EEG analysis and neuroimaging tools like MRI and transcranial Doppler, the lab explores the relationships between nocturnal blood pressure dipping, cerebral microbleeds, and cerebrovascular compliance in hypertensive and stroke patients. The research aims to improve diagnostic accuracy, surgical planning, and long-term outcomes in patients with refractory epilepsy and cerebrovascular risk factors.

epilepsycerebral small vessel diseasesleep apneaEEG analysiscerebrovascular compliance

Research Overview

Papers
124
Total Citations
1,659
Papers (5y)
22
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
22total
2022
2023
2024
2025
2026
Citations per year (5y)
180total
20222023202420252026

Selected Papers

15
1
Article|80 citations·2002
Independent Component Analysis of Ictal EEG in Medial Temporal Lobe Epilepsy
Hyunwoo Nam, Tae‐Gyu Yim, Seung Kee Han, Jong‐Bai Oh, S K Lee
SJR Q1EpilepsiaOA

PURPOSE: Application of independent component analysis (ICA) to interictal EEGs and to event-related potentials has helped noise reduction and source localization. However, ICA has not been used for the analysis of ictal EEGs in partial seizures. In this study, we applied ICA to the ictal EEGs of patients with medial temporal lobe epilepsy (TLE) and investigated whether ictal components can be separated and whether they indicate correct lateralization. METHODS: Twenty-four EEGs from medial TLE p

Cognitive NeuroscienceNeuroscience
2
Article|47 citations·2009
Epilepsy with dual pathology: Surgical treatment of cortical dysplasia accompanied by hippocampal sclerosis
Dong Wook Kim, Sang K. Lee, Hyunwoo Nam, Kon Chu, Chun Kee Chung, Seo‐Young Lee, Geeyoung Choe, Hyun Koo Kim
SJR Q1EpilepsiaOA

PURPOSE: The presence of two or more epileptogenic pathologies in patients with epilepsy is often observed, and the coexistence of focal cortical dysplasia (FCD) with hippocampal sclerosis (HS) is one of the most frequent clinical presentations. Although surgical resection has been an important treatment for patients with refractory epilepsy associated with FCD, there are few studies on the surgical treatment of FCD accompanied by HS, and treatment by resection of both neocortical dysplastic tis

Psychiatry and Mental healthMedicine
3
Article|37 citations·2008
Reliability of Semiology Description
Jae‐Hyeok Heo, Dong Wook Kim, Seo‐Young Lee, Jinwhan Cho, Sang Kun Lee, Hyunwoo Nam
SJR Q3The Neurologist

Much of the information described by well-educated observers is reliable. However, every physician should keep in mind the limitations of this information and use this information cautiously.

Psychiatry and Mental healthMedicine
4
Article|33 citations·2016
Sleep Perception in Obstructive Sleep Apnea: A Study Using Polysomnography and the Multiple Sleep Latency Test
Hyunwoo Nam, Jae‐Sung Lim, Jun-Soon Kim, Keon‐Joo Lee, Dae Lim Koo, Chulhee Lee
SJR Q2Journal of Clinical NeurologyOA

As an objectively good sleep does not match the subjective good-sleep perception in OSA, physicians should keep in mind that OSA patients who perceive that they have slept well does not mean that their OSA is less severe.

PhysiologyMedicine
5
Article|29 citations·2017
Cerebral Microbleeds on MRI in Patients with Obstructive Sleep Apnea
Dae Lim Koo, Jun Yup Kim, Jae‐Sung Lim, Hyung‐Min Kwon, Hyunwoo Nam
SJR Q1Journal of Clinical Sleep MedicineOA
PhysiologyMedicine
6
Article|27 citations·2018
Association between periodic limb movements during sleep and cerebral small vessel disease
Min Kyoung Kang, Dae Lim Koo, Jung Hwan Shin, Hyung‐Min Kwon, Hyunwoo Nam
SJR Q1Sleep Medicine
EpidemiologyMedicine
7
Article|24 citations·2014
Cerebral microbleeds are associated with nocturnal reverse dipping in hypertensive patients with ischemic stroke
Hyung‐Min Kwon, Jae‐Sung Lim, Young Seo Kim, Jangsup Moon, Hyeri Park, Ho Kim, Young‐Hyo Lim, Hyunwoo Nam
SJR Q2BMC NeurologyOA

BACKGROUND: Abnormalities in nocturnal blood pressure dipping are well known for its relationship to cardiovascular diseases. Cerebral microbleeds are frequently observed in patients with hypertension and are known to be potent risk factors for stroke. However, there are scanty reports about the relationship between nocturnal dipping and cerebral microbleeds. METHODS: We recruited consecutive patients with both hypertension and ischemic stroke within 7 days after symptom onset, and those with ca

NeurologyMedicine
8
Article|24 citations·2021
Effect of obstructive sleep apnea on cerebrovascular compliance and cerebral small vessel disease
Woo‐Jin Lee, Keun‐Hwa Jung, Hyunwoo Nam, Yong-Seok Lee
SJR Q1PLoS ONEOA

Reduced cerebrovascular compliance is the major mechanism of cerebral small vessel disease (SVD). Obstructive sleep apnea (OSA) also promotes SVD development, but the underlying mechanism was not elucidated. We investigated the association among OSA, cerebrovascular compliance, and SVD parameters. This study retrospectively included individuals ≥ 50 years of age, underwent overnight polysomnographic (PSG) for the evaluation of OSA, and performed MRI and transcranial Doppler (TCD) within 12 month

PhysiologyMedicine
9
Article|19 citations·2016
Acoustic Characteristics of Stridor in Multiple System Atrophy
Dae Lim Koo, Jee‐Young Lee, Eun Yeon Joo, Seung Bong Hong, Hyunwoo Nam
SJR Q1PLoS ONEOA

Nocturnal stridor is a breathing disorder prevalent in patients with multiple system atrophy (MSA). An improved understanding of this breathing disorder is essential since nocturnal stridor carries a poor prognosis (an increased risk of sudden death). In this study, we aimed to classify types of stridor by sound analysis and to reveal their clinical significance. Patients who met the criteria for probable MSA and had undergone polysomnography (PSG) were recruited. Patients were then assessed cli

NeurologyMedicine
10
Article|14 citations·2020
Moderate to severe obstructive sleep apnea during REM sleep as a predictor of metabolic syndrome in a Korean population
Dae Lim Koo, Hang-Rai Kim, Hyunwoo Nam
SJR Q1Sleep And Breathing
PhysiologyMedicine
11
Article|14 citations·2011
The effect of propranolol on cerebrovascular reactivity to visual stimulation in migraine
Ju‐Hong Min, Hyung‐Min Kwon, Hyunwoo Nam
SJR Q1Journal of the Neurological Sciences
Psychiatry and Mental healthMedicine
12
Article|12 citations·2020
Effects of zonisamide monotherapy on bone health in drug‐naive epileptic patients
Dae Lim Koo, Hyunwoo Nam
SJR Q1Epilepsia

OBJECTIVE: Alteration of bone strength is an adverse effect of antiepileptic drug treatment. We investigated the effects of zonisamide (ZNS) monotherapy on bone mineral density (BMD) and biomarkers of bone metabolism after 13 months of treatment in drug-naive epileptic patients. METHODS: Fifty-nine patients with new onset drug-naive epilepsy were enrolled (29 women, 30 men; mean age = 31.5 ± 11.5 years). The BMD and T scores were measured at the lumbar spine and femoral neck by using dual-energy

Pediatrics, Perinatology and Child HealthMedicine
13
Article|11 citations·2009
Does Multiple System Atrophy Itself Affect Sleep Structure?
Hyunwoo Nam, Yoon‐Ho Hong, Hyung‐Min Kwon, Jinwhan Cho
SJR Q3The Neurologist

MSA itself does not affect the macro- and microstructures of sleep. However, patients with MSA sleep less and it cannot be explained by obstructive sleep apnea and periodic limb movements during sleep.

NeurologyMedicine
14
Article|11 citations·2021
Mild cognitive impairment and abnormal brain metabolic expression in idiopathic REM sleep behavior disorder
Dallah Yoo, Jee‐Young Lee, Yu Kyeong Kim, Eun Jin Yoon, Heejung Kim, Ryul Kim, Hyunwoo Nam, Beomseok Jeon
SJR Q1Parkinsonism & Related Disorders
NeurologyMedicine
15
Article|9 citations·2013
A mobile video traffic analysis: Badly designed video clients can waste network bandwidth
Hyunwoo Nam, Bong Ho Kim, Doru Calin, Henning Schulzrinne

Video streaming on mobile devices is on the rise. According to recent reports, mobile video streaming traffic accounted for 52.8% of total mobile data traffic in 2011, and it is forecast to reach 66.4% in 2015. We analyzed the network traffic behaviors of the two most popular HTTP-based video streaming services: YouTube and Netflix. Our research indicates that the network traffic behavior depends on factors such as the type of device, multimedia applications in use and network conditions. Furthe

Computer Vision and Pattern RecognitionComputer Science

Research Areas

NeurologyPhysiologyPsychiatry and Mental healthCognitive NeuroscienceEpidemiologyDermatology

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