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Ikjun Cho

Sungkyunkwan University · Medicine

About the Lab

Professor Ikjun Cho's research lab specializes in critical care medicine, with a primary focus on improving outcomes in severe critical illnesses such as sepsis, septic shock, and cardiac arrest. The lab investigates prognostic biomarkers—particularly lactate, albumin, CRP, and procalcitonin—to predict mortality and guide early intervention. It also examines the impact of systemic factors like emergency department crowding and advanced resuscitation techniques such as extracorporeal cardiopulmonary resuscitation on patient survival and neurological outcomes. The research emphasizes evidence-based, early resuscitation strategies aligned with international guidelines.

sepsiscardiac arrestprognostic biomarkerscritical careresuscitation

Research Overview

Papers
179
Total Citations
3,766
Papers (5y)
36
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
36total
2021
2022
2023
2024
2025
Citations per year (5y)
196total
20212022202320242025

Selected Papers

15
1
Article|417 citations·2010
Extracorporeal cardiopulmonary resuscitation in patients with inhospital cardiac arrest: A comparison with conventional cardiopulmonary resuscitation*
Tae Gun Shin, Jin‐Ho Choi, Ik Joon Jo, Min Seob Sim, Hyoung Gon Song, Yeon Kwon Jeong, Yong-Bien Song, Joo‐Yong Hahn, Seung‐Hyuk Choi, Hyeon‐Cheol Gwon, Eun‐Seok Jeon, Kiick Sung
SJR Q1Critical Care Medicine

OBJECTIVE: We investigated whether the survival of patients with inhospital cardiac arrest could be extended by extracorporeal cardiopulmonary resuscitation supported with extracorporeal membrane oxygenation compared with those of conventional cardiopulmonary resuscitation. DESIGN: : A retrospective, single-center, observational study. SETTING: A tertiary care university hospital. PATIENTS: We retrospectively analyzed a total of 406 adult patients with witnessed inhospital cardiac arrest receivi

Emergency MedicineMedicine
2
Article|334 citations·2016
MERS-CoV outbreak following a single patient exposure in an emergency room in South Korea: an epidemiological outbreak study
Sun Young Cho, Ji‐Man Kang, Young Eun Ha, Ga Eun Park, Ji Yeon Lee, Jae‐Hoon Ko, Ji‐Yong Lee, Jong Min Kim, Cheol‐In Kang, Ik Joon Jo, Jae Geum Ryu, Jong Rim Choi
SJR Q1The LancetOA
Pulmonary and Respiratory MedicineMedicine
3
Article|230 citations·2016
Neutrophil-to-lymphocyte ratio as a prognostic marker in critically-ill septic patients
Sung Yeon Hwang, Tae Gun Shin, Ik Joon Jo, Kyeongman Jeon, Gee Young Suh, Tae Rim Lee, Hee Yoon, Won Chul, Min Seob Sim
SJR Q1The American Journal of Emergency Medicine
EpidemiologyMedicine
4
Article|167 citations·2013
Two-year survival and neurological outcome of in-hospital cardiac arrest patients rescued by extracorporeal cardiopulmonary resuscitation
Tae Gun Shin, Ik Joon Jo, Min Seob Sim, Yong-Bien Song, Jung-Hoon Yang, Joo‐Yong Hahn, Seung‐Hyuk Choi, Hyeon‐Cheol Gwon, Eun‐Seok Jeon, Kiick Sung, Young Tak Lee, Jin‐Ho Choi
SJR Q1International Journal of Cardiology
Emergency MedicineMedicine
5
Article|157 citations·2020
Combination therapy of vitamin C and thiamine for septic shock: a multi-centre, double-blinded randomized, controlled study
Sung Yeon Hwang, Seung Mok Ryoo, Jong Eun Park, You Hwan Jo, Dong‐Hyun Jang, Gil Joon Suh, Taegyun Kim, Youn‐Jung Kim, Seonwoo Kim, Hyun Cho, Ik Joon Jo, Sung Phil Chung
SJR Q1Intensive Care MedicineOA
Nutrition and DieteticsNursing
6
Article|131 citations·2018
Prognostic Value of The Lactate/Albumin Ratio for Predicting 28-Day Mortality in Critically ILL Sepsis Patients
Jikyoung Shin, Sung Yeon Hwang, Ik Joon Jo, Won Young Kim, Seung Mok Ryoo, Gu Hyun Kang, Kyuseok Kim, You Hwan Jo, Sung Phil Chung, Young Seon Joo, Jin Ho Beom, Young‐Hoon Yoon
SJR Q1ShockOA

AIM: The aim of this study was to evaluate the clinical utility of the lactate/albumin (L/A) ratio as a predictive factor of 28-day mortality in critically ill sepsis patients. METHODS: This is a retrospective observational study from a prospectively collected multicenter registry of 10 emergency departments (EDs) in teaching hospitals that participated in the Korean Shock Society. It enrolled patients who were 19 years of age or older who had a suspected or confirmed infection and evidence of r

EpidemiologyMedicine
7
Article|117 citations·2017
Low Accuracy of Positive qSOFA Criteria for Predicting 28-Day Mortality in Critically Ill Septic Patients During the Early Period After Emergency Department Presentation
Sung Yeon Hwang, Ik Joon Jo, Se Uk Lee, Tae Rim Lee, Hee Yoon, Won Chul, Min Seob Sim, Tae Gun Shin
SJR Q1Annals of Emergency Medicine
EpidemiologyMedicine
8
Article|94 citations·2019
The usefulness of C-reactive protein and procalcitonin to predict prognosis in septic shock patients: A multicenter prospective registry-based observational study
Seung Mok Ryoo, Kap Su Han, Shin Ahn, Tae Gun Shin, Sung Yeon Hwang, Sung Phil Chung, Yoon Jung Hwang, Yoo Seok Park, You Hwan Jo, Hyunglan Chang, Gil Joon Suh, Kyoung Min You
SJR Q1Scientific ReportsOA

The objective of this study was to evaluate the prognostic value of C-reactive protein (CRP), procalcitonin (PCT), and their combination for mortality in patients with septic shock. This multicenter, prospective, observational study was conducted between November 2015 and December 2017. A total of 1,772 septic shock patients were included, and the overall 28-day mortality was 20.7%. Although both CRP and PCT were elevated in the non-survivor group, only CRP had statistical significance (11.9 mg/

EpidemiologyMedicine
9
Article|90 citations·2013
The adverse effect of emergency department crowding on compliance with the resuscitation bundle in the management of severe sepsis and septic shock
Tae Gun Shin, Ik Joon Jo, Dae Jong Choi, Mun Ju Kang, Kyeongman Jeon, Gee Young Suh, Min Seob Sim, So Yeon Lim, Keun Jeong Song, Yeon Kwon Jeong
SJR Q1Critical CareOA

INTRODUCTION: The aim of this study is to evaluate the effects of emergency department (ED) crowding on the implementation of tasks in the early resuscitation bundle during acute care of patients with severe sepsis and septic shock, as recommended by the Surviving Sepsis Campaign guidelines. METHODS: We analyzed the sepsis registry from August 2008 to March 2012 for patients presenting to an ED of a tertiary urban hospital and meeting the criteria for severe sepsis or septic shock. The ED occupa

EpidemiologyMedicine
10
Article|80 citations·2017
Serologic responses of 42 MERS-coronavirus-infected patients according to the disease severity
Jae‐Hoon Ko, Marcel A. Müller, Hyeri Seok, Ga Eun Park, Ji Yeon Lee, Sun Young Cho, Young Eun Ha, Jin Yang Baek, Kim Ys, Ji‐Man Kang, Yae‐Jean Kim, Ik Joon Jo
SJR Q2Diagnostic Microbiology and Infectious DiseaseOA
Infectious DiseasesMedicine
11
Article|71 citations·2013
Better lactate clearance associated with good neurologic outcome in survivors who treated with therapeutic hypothermia after out-of-hospital cardiac arrest
Tae Rim Lee, Mun Ju Kang, Won Chul Cha, Tae Gun Shin, Min Seob Sim, Ik Joon Jo, Keun Jeong Song, Yeon Kwon Jeong, Jun Hwi Cho
SJR Q1Critical CareOA

INTRODUCTION: Several methods have been proposed to evaluate neurological outcome in out-of-hospital cardiac arrest (OHCA) patients. Blood lactate has been recognized as a reliable prognostic marker for trauma, sepsis, or cardiac arrest. The objective of this study was to examine the association between initial lactate level or lactate clearance and neurologic outcome in OHCA survivors who were treated with therapeutic hypothermia. METHODS: This retrospective cohort study included patients who u

Emergency MedicineMedicine
12
Article|68 citations·2015
Contamination during doffing of personal protective equipment by healthcare providers
Seong Mi Lim, Won Chul, Minjung Kathy Chae, Ik Joon Jo
SJR Q1Clinical and Experimental Emergency MedicineOA

A significant number of contaminations occur during the doffing process of personal protective equipment.

Infectious DiseasesMedicine
13
Article|63 citations·2016
Impact of Metformin Use on Lactate Kinetics in Patients with Severe Sepsis and Septic Shock
Joong‐Min Park, Sung Yeon Hwang, Ik Joon Jo, Kyeongman Jeon, Gee Young Suh, Tae Rim Lee, Hee Yoon, Won Chul, Min Seob Sim, Keumhee C. Carrière, Seungmin Yeon, Tae Gun Shin
SJR Q1Shock

Lactate levels in metformin users were initially elevated in the early phase of resuscitation from severe sepsis and septic shock. However, there was no significant difference in lactate levels, LC, and normalization over the initial 24 h period based on metformin use.

EpidemiologyMedicine
14
Article|62 citations·2016
Better prognostic value with combined optic nerve sheath diameter and grey-to-white matter ratio on initial brain computed tomography in post-cardiac arrest patients
Minjung Kathy Chae, Eunsil Ko, Jeong Hoon Lee, Tae Rim Lee, Hee Yoon, Sung Yeon Hwang, Won Chul, Tae Gun Shin, Min Seob Sim, Ik Joon Jo, Keun Jeong Song, Joong Eui Rhee
SJR Q1Resuscitation
NeurologyMedicine
15
Article|62 citations·2015
Comprehensive Interpretation of Central Venous Oxygen Saturation and Blood Lactate Levels During Resuscitation of Patients With Severe Sepsis and Septic Shock in the Emergency Department
Tae Gun Shin, Ik Joon Jo, Sung Yeon Hwang, Kyeongman Jeon, Gee Young Suh, Euna Choe, Young Kun Lee, Tae Rim Lee, Won Chul, Min Seob Sim
SJR Q1Shock

Oxygenation category, as represented by initial Scvo2 and lactate levels, was significantly associated with 28-day mortality in patients with severe sepsis or septic shock. Associations between Scvo2 ≥70% and 28-day survival were observed only in patients without severe lactic acidosis.

EpidemiologyMedicine

Research Areas

Emergency MedicineEpidemiologySurgeryPulmonary and Respiratory MedicinePublic Health, Environmental and Occupational HealthCritical Care and Intensive Care Medicine

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