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In Ho Yang

Kyung Hee University · Medicine

About the Lab

Professor In Ho Yang's research lab specializes in cardiovascular imaging and functional assessment, with a focus on understanding the pathophysiology of acute and chronic cardiac conditions through advanced echocardiographic techniques, cardiac MRI, and hemodynamic evaluation. The lab investigates myocardial deformation, autonomic function, arterial stiffness, and the long-term outcomes of complex interventional procedures in patients with acute myocardial infarction and cardiomyopathies. Key research directions include early detection of coronary artery disease using speckle tracking echocardiography, the role of stress-induced vascular changes, and the clinical implications of rare or atypical cardiac presentations such as takotsubo cardiomyopathy and acromegaly-related heart failure despite normal IGF-1 levels.

cardiovascular imagingmyocardial deformationcoronary artery diseaseacute myocardial infarctionarterial stiffness

Research Overview

Papers
21
Total Citations
77
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2020
2022
2024
2025
2026
Citations per year (5y)
12total
20202022202420252026

Selected Papers

15
1
Article|19 citations·2014
Evolutionary Change Mimicking Apical Hypertrophic Cardiomyopathy in a Patient with Takotsubo Cardiomyopathy
Hui‐Jeong Hwang, Hyae‐Min Lee, In‐Ho Yang, Donghee Kim, Jong‐Kyu Byun, Il Suk Sohn
SJR Q3Echocardiography

In this report, we introduce a case of thickening of the involved left ventricular apical segment on echocardiography and deep T-wave inversions in precordial leads on electrocardiography transiently seen in the course of recovery from biventricular takotsubo cardiomyopathy, mimicking apical hypertrophic cardiomyopathy. This result suggests that the echocardiographic finding of transient myocardial edema can be identified by cardiac magnetic resonance imaging in takotsubo cardiomyopathy. Additio

Cardiology and Cardiovascular MedicineMedicine
2
Article|17 citations·2014
The Value of Assessing Myocardial Deformation at Recovery after Dobutamine Stress Echocardiography
Hui‐Jeong Hwang, Hyae‐Min Lee, In‐Ho Yang, Jung Lok Lee, Hyun Y. Pak, Chang‐Bum Park, Eun‐Sun Jin, Jin‐Man Cho, Chong‐Jin Kim, Il Suk Sohn
Journal of Cardiovascular UltrasoundOA

BACKGROUND: The purpose of this study was to evaluate whether performing an assessment of myocardial deformation using speckle tracking imaging during the recovery period after dobutamine stress echocardiography (DSE) allows detection of significant coronary artery disease (CAD) in patients with chest discomfort. METHODS: DSE and coronary angiography were performed in 44 patients with chest discomfort. The mean global longitudinal peak systolic strain (GLS) was measured at rest, at low stress (d

Cardiology and Cardiovascular MedicineMedicine
3
Article|12 citations·2019
Slow Heart Rate Recovery Is Associated with Increased Exercise-induced Arterial Stiffness in Normotensive Patients without Overt Atherosclerosis
In‐Ho Yang, Hui‐Jeong Hwang, Hong Ki Jeon, Il Suk Sohn, Chang-Bum Park, Eun‐Sun Jin, Jin Man Cho, Chong Jin Kim, Taek‐Gu Lee
SJR Q2Journal of Cardiovascular ImagingOA

BACKGROUND: This study evaluated whether blunted autonomic activity as measured by heart rate recovery (HRR) was associated with increased arterial stiffness, especially increased exercise-induced arterial stiffness, in normotensive patients without overt atherosclerosis. METHODS: One hundred fifty-four normotensive patients without overt atherosclerosis who had undergone a treadmill exercise test were consecutively enrolled. HRR was measured at one minute after exercise. Brachial-ankle pulse wa

Cardiology and Cardiovascular MedicineMedicine
4
Article|10 citations·2015
Acromegaly with Normal Insulin-Like Growth Factor-1 Levels and Congestive Heart Failure as the First Clinical Manifestation
Hyae Min Lee, Sun Hee Lee, In‐Ho Yang, In Kyoung Hwang, You‐Cheol Hwang, Kyu Jeung Ahn, Ho Yeon Chung, Hui‐Jeong Hwang, In‐Kyung Jeong
SJR Q1Endocrinology and MetabolismOA

The leading cause of morbidity and mortality in patients with acromegaly is cardiovascular complications. Myocardial exposure to excessive growth hormone can cause ventricular hypertrophy, hypertension, arrhythmia, and diastolic dysfunction. However, congestive heart failure as a result of systolic dysfunction is observed only rarely in patients with acromegaly. Most cases of acromegaly exhibit high levels of serum insulin-like growth factor-1 (IGF-1). Acromegaly with normal IGF-1 levels is rare

Endocrinology, Diabetes and MetabolismMedicine
5
Article|3 citations·2022
Independent Clinical Impacts of Procedural Complexity on Ischemic and Bleeding Events in Patients with Acute Myocardial Infarction: Long-Term Clinical Study
Kwan Yong Lee, Byung‐Hee Hwang, Sungmin Lim, Chan Jun Kim, Eun Ho Choo, Seung‐Hoon Lee, Jin-Jin Kim, Ik Jun Choi, Gyu Chul Oh, In‐Ho Yang, Ki‐Dong Yoo, Wook Sung Chung
SJR Q1Journal of Clinical MedicineOA

This study aimed to investigate the relationship between a complex percutaneous coronary intervention (C-PCI) and long-term clinical outcomes in the AMI cohort. A total of 10,329 patients were categorized into the C-PCI and non-C-PCI groups. The primary ischemic endpoint was a composite of major adverse cardiac events (MACEs, cardiac death, myocardial infarction, stent thrombosis and revascularization). The primary bleeding endpoint was the risk of overt bleeding (BARC 2, 3 or 5). The median fol

Cardiology and Cardiovascular MedicineMedicine
6
letter|3 citations·2015
Transradial intervention versus transfemoral intervention accompanied with vascular closure device in acute myocardial infarction
Hui‐Jeong Hwang, Sung Jin Kwon, Chang‐Bum Park, Dong-Whee Kim, In‐Ho Yang, Hyemin Lee, Jin‐Man Cho, Hyun‐Young Park, Eun‐Sun Jin, Il Seok Son, Chong‐Jin Kim
SJR Q1International Journal of Cardiology
Pulmonary and Respiratory MedicineMedicine
7
Article|3 citations·2022
Prognostic Impact of the HFA-PEFF Score in Patients with Acute Myocardial Infarction and an Intermediate to High HFA-PEFF Score
Kwan Yong Lee, Byung‐Hee Hwang, Chan Jun Kim, Young Kyoung, Young Choi, Jin-Jin Kim, Eun Ho Choo, Sungmin Lim, Ik Jun Choi, Mahn‐Won Park, Gyu Chul Oh, In‐Ho Yang
SJR Q1Journal of Clinical MedicineOA

This study aimed to investigate the efficacy of the HFA-PEFF score in predicting the long-term risks in patients with acute myocardial infarction (AMI) and an HFA-PEFF score ≥ 2. The subjects were divided according to their HFA-PEFF score into intermediate (2−3 points) and high (4−6 points) score groups. The primary outcome was all-cause mortality. Of 1018 patients with AMI and an HFA-PEFF score of ≥2, 712 (69.9%) and 306 (30.1%) were classified into the intermediate and high score groups, respe

Cardiology and Cardiovascular MedicineMedicine
8
Article|3 citations·2019
Predictive Performance of Ultrasound-Determined Non-Alcoholic Fatty Pancreas Disease Severity for Intermediate and High Risk of Coronary Heart Disease
Younghoon An, Seong Jong Yun, In‐Ho Yang, Dong Hyeon Kim, Dal Mo Yang
SJR Q4Journal of the Korean Society of RadiologyOA

Purpose To evaluate non-alcoholic fatty pancreas disease severity on ultrasound (US-determined NAFPD) as a risk factor for coronary heart disease (CHD) and to evaluate its predictive value for intermediate/high CHD risk compared with US-determined non-alcoholic fatty liver disease (US-determined NAFLD) severity.

EpidemiologyMedicine
9
Article|3 citations·2025
Coronary artery ectasia presenting as acute coronary syndrome and misinterpreted as coronary artery perforation: Case report
Hong Ki Jeon, Jin Man Cho, In‐Ho Yang, Narae Kim, Chang-Bum Park
SJR Q3MedicineOA

RATIONALE: Coronary artery ectasia (CAE), characterized by diffuse dilation, can be associated with total thrombotic occlusion, leading to acute coronary syndrome. In such cases, distal vessel morphology can be highly unpredictable, potentially causing confusion during percutaneous coronary intervention (PCI). PATIENT CONCERNS: A 47-year-old man presented with sudden chest pain. Acute coronary syndrome was suspected based on symptom and elevated troponin I levels. DIAGNOSES: Coronary angiography

SurgeryMedicine
10
Article|1 citations·2014
A Latent Autoimmune Diabetes in Adults Patient Manifesting Severe Musculoskeletal Complications
In‐Ho Yang, Sun Hee Lee, Sang Ouk Chin, Suk Chon
SJR Q2Journal of Bone MetabolismOA

Patients with diabetes have many different kinds of complications involving multiple organs, but those involving the musculoskeletal system are relatively uncommon. Diabetic muscle infarction (DMI) is a rare, painful, and potentially serious condition in patients with poorly controlled diabetes mellitus. A 35-year-old man diagnosed with type 2 diabetes eight years ago, visited with severe muscle pain in the right anteromedial thigh without any event of trauma. He had been treated with metformin,

Psychiatry and Mental healthMedicine
11
Article|1 citations·2024
Cardiac remodeling in elite young Asian female soccer players
Narae Kim, Hyunkyung Park, Il Suk Sohn, In‐Ho Yang
SJR Q1Frontiers in Cardiovascular MedicineOA

Introduction: An athlete's heart (AH) varies depending on race, sex, age, and the type and intensity of training. Given that soccer is a common sport, evaluation of cardiac function in soccer players is important; however, few studies have analyzed adolescent soccer players. Therefore, this study, aimed to identify early changes in AH in soccer players by evaluating the echocardiographic findings of adolescent Asian female soccer players for whom existing data are scarce. Methods: We evaluated 2

Cardiology and Cardiovascular MedicineMedicine
12
Article|1 citations·2024
Aborted sudden cardiac death in a young male with rheumatoid arthritis; case report
Narae Kim, Sang-Ho Cho, In‐Ho Yang
SJR Q4Journal of the Pakistan Medical AssociationOA

Rheumatoid arthritis (RA) causes coronary artery atherosclerosis with a similar risk as diabetes or hypertension. However, coronary artery disease (CAD) is rare in young patients, especially in those presenting as chronic total occlusion (CTO). We report a rare case of aborted sudden cardiac death in a 26-year-old patient with a six-year history of RA. He had no cardiovascular risk factors apart from RA. He was diagnosed with severe ischaemic heart failure (HF) due to recent myocardial ischaemia

Cardiology and Cardiovascular MedicineMedicine
13
Article|1 citations·2024
Recurrent Acute Coronary Syndrome in Young Man with Familial Hypercholesterolemia: Efficacy of Evolocumab Add-On Treatment Demonstrated via Serial Coronary Angiography
Narae Kim, Jin‐Man Cho, In‐Ho Yang
SJR Q1BiomedicinesOA

In patients with acute coronary syndrome (ACS), lipid-lowering therapy plays an important role in the prevention of the recurrence of cardiovascular disease. Recent guidelines recommend the use of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in patients with ACS if their low-density lipoprotein cholesterol (LDL-C) levels are not adequately controlled with statins and ezetimibe. Based on this, we report a case in which administering a PCSK9 inhibitor successfully lowered the p

SurgeryMedicine
14
Article|0 citations·2019
Early versus delayed treatment with ticagrelor on residual thrombus after percutaneous coronary intervention in patients presenting with non-ST-elevation acute coronary syndrome: an optical coherence tomography study
In‐Ho Yang, Jin‐Man Cho, Hong Ki Jeon, Chang‐Bum Park, Tomoyo Sugiyama, Gregory Gheewalla, Hyuck‐Jun Yoon, Soo–Joong Kim, Ik‐Kyung Jang, Chong‐Jin Kim
SJR Q3Coronary Artery DiseaseOA

Ticagrelor, a P2Y12 antagonist, is well known for its rapid, high-potent inhibition of platelet aggregation by pharmacokinetic studies [1]. In the PLATO study, ticagrelor, compared to clopidogrel, reduced the incidence of myocardial infarction, stroke, cardiovascular death and definite stent thrombosis, during 12-month follow-up in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) [2,3]. To date, the effect of early ticagrelor administration versus t

Cardiology and Cardiovascular MedicineMedicine
15
Article|0 citations·2024
Ischemia with Non-Obstructive Coronary Arteries
In‐Ho Yang, Jong Shin Woo, Sang Jin Ha
Korean Journal of MedicineOA

Many patients with angina or evidence of myocardial ischemia on noninvasive tests have no obstructive coronary artery disease. Ischemia with non-obstructive coronary arteries (INOCA) has been underrecognized despite its association with poor quality of life and effect on cardiovascular events. Two major mechanisms, coronary microvascular dysfunction (CMD) and coronary vasospasm, are keys to INOCA pathophysiology. Although noninvasive tests, such as stress echocardiography, cardiac positron emiss

Radiology, Nuclear Medicine and ImagingMedicine

Research Areas

Cardiology and Cardiovascular MedicineSurgeryEndocrinology, Diabetes and MetabolismRadiology, Nuclear Medicine and ImagingEpidemiologyPulmonary and Respiratory Medicine

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