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Ja-Keung Yoon

Yonsei University · Medicine

About the Lab

Professor Ja-Keung Yoon's research lab specializes in medical imaging and diagnostic radiology, with a focus on advancing MRI techniques for liver and pancreatic cancer detection. The lab investigates innovative imaging methods such as compressed sensing and parallel imaging to improve scan efficiency and image quality in dynamic contrast-enhanced MRI. It also explores the application of artificial intelligence, particularly deep learning, in interpreting pediatric abdominal radiographs for early diagnosis of conditions like intussusception. Additionally, the lab examines molecular imaging biomarkers and sarcopenia assessment to support personalized cancer diagnosis and prognosis.

medical imagingMRIartificial intelligencecancer diagnosissarcopenia

Research Overview

Papers
32
Total Citations
423
Papers (5y)
23
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
23total
2021
2022
2023
2024
2025
Citations per year (5y)
170total
20212022202320242025

Selected Papers

15
1
Article|81 citations·2009
An efficient gene-disruption method in Cryptococcus neoformans by double-joint PCR with NAT-split markers
Min Su Kim, Seoyoung Kim, Ja Kyung Yoon, Yin-Won Lee, Yong‐Sun Bahn
SJR Q2Biochemical and Biophysical Research Communications
EpidemiologyMedicine
2
Article|46 citations·2019
Compressed Sensing and Parallel Imaging for Double Hepatic Arterial Phase Acquisition in Gadoxetate-Enhanced Dynamic Liver Magnetic Resonance Imaging
Ja Kyung Yoon, Myeong‐Jin Kim, Sunyoung Lee
SJR Q1Investigative RadiologyOA

OBJECTIVES: The aim of this study was to investigate the utility of a combined compressed sensing and parallel imaging (C-SENSE) technique for single breath-hold, double arterial phase (AP) examinations in gadoxetate-enhanced magnetic resonance imaging (MRI) of the liver. MATERIALS AND METHODS: We retrospectively reviewed single breath-hold, double AP images obtained by using a C-SENSE technique for gadoxetate-enhanced dynamic liver MRI in a total of 127 patients (89 men and 38 women; mean age,

Radiology, Nuclear Medicine and ImagingMedicine
3
Article|37 citations·2020
Application of Liver Imaging Reporting and Data System version 2018 ancillary features to upgrade from LR-4 to LR-5 on gadoxetic acid–enhanced MRI
Sunyoung Lee, Seung‐seob Kim, Heejin Bae, Jaeseung Shin, Ja Kyung Yoon, Myeong‐Jin Kim
SJR Q1European RadiologyOA
HepatologyMedicine
4
Review|32 citations·2021
LI‐RADS Major Features on MRI for Diagnosing Hepatocellular Carcinoma: A Systematic Review and Meta‐Analysis
Jaeseung Shin, Sunyoung Lee, Ja Kyung Yoon, Yong Eun Chung, Jin‐Young Choi, Mi‐Suk Park
SJR Q1Journal of Magnetic Resonance ImagingOA

BACKGROUND: The reported diagnostic performance for hepatocellular carcinoma (HCC) of each major imaging feature on MRI using standardized definitions of the Liver Imaging Reporting and Data System (LI-RADS) is variable. It is important to know the actual performance of each LI-RADS major imaging feature for imaging diagnosis of HCC and determine the sources of heterogeneity between the reported results. PURPOSE: To systematically determine the performance of each major imaging feature of LI-RAD

HepatologyMedicine
5
Review|31 citations·2022
MRI features of histologic subtypes of hepatocellular carcinoma: correlation with histologic, genetic, and molecular biologic classification
Ja Kyung Yoon, Jin‐Young Choi, Hyungjin Rhee, Young Nyun Park
SJR Q1European RadiologyOA
SurgeryMedicine
6
Article|30 citations·2021
Reference Values for Skeletal Muscle Mass at the Third Lumbar Vertebral Level Measured by Computed Tomography in a Healthy Korean Population
Ja Kyung Yoon, Sunyoung Lee, Kyung Won Kim, Ji Eun Lee, Jeong Ah Hwang, Taeyong Park, Jeongjin Lee
SJR Q1Endocrinology and MetabolismOA

Our data provide sex-specific cutoff values for the SMA and SMI at the L3 level measured by CT imaging in a healthy Korean population, which may be applicable for identifying sarcopenia in this population.

PhysiologyMedicine
7
Article|25 citations·2019
Performance of deep learning-based algorithm for detection of ileocolic intussusception on abdominal radiographs of young children
Sung‐Won Kim, Haesung Yoon, Mi‐Jung Lee, Myung‐Joon Kim, Kyunghwa Han, Ja Kyung Yoon, Hyung Cheol Kim, Jaeseung Shin, Hyun Joo Shin
SJR Q1Scientific ReportsOA

The purpose of this study was to develop and test the performance of a deep learning-based algorithm to detect ileocolic intussusception using abdominal radiographs of young children. For the training set, children (≤5 years old) who underwent abdominal radiograph and ultrasonography (US) for suspicion of intussusception from March 2005 to December 2017 were retrospectively included and divided into control and intussusception groups according to the US results. A YOLOv3-based algorithm was deve

SurgeryMedicine
8
Article|21 citations·2014
Implications of differences in expression of sarcosine metabolism-related proteins according to the molecular subtype of breast cancer
Ja Kyung Yoon, Do Hee Kim, Ja Seung Koo
SJR Q1Journal of Translational MedicineOA

BACKGROUND: The goal of this study was to investigate the expression of sarcosine metabolism-related proteins, namely glycine N-methyltransferase (GNMT), sarcosine dehydrogenase (SARDH), and l-pipecolic acid oxidase (PIPOX), in the different breast cancer subtypes and to assess the implications of differences in expression pattern according to subtype. METHODS: We analyzed the expression of GNMT, SARDH, and PIPOX in a tissue microarray of 721 breast cancer cases using immunohistochemistry (IHC).

Cancer ResearchBiochemistry, Genetics and Molecular Biology
9
Article|20 citations·2018
Five-year clinical outcomes of uterine artery embolization for symptomatic leiomyomas: An analysis of risk factors for reintervention
Ja Kyung Yoon, Kichang Han, Man Deuk Kim, Gyoung Min Kim, Joon Ho Kwon, Jong Yun Won, Do Yun Lee
SJR Q1European Journal of RadiologyOA
Obstetrics and GynecologyMedicine
10
Article|16 citations·2022
Regional lymph node metastasis detected on preoperative CT and/or FDG-PET may predict early recurrence of pancreatic adenocarcinoma after curative resection
Ja Kyung Yoon, Mi‐Suk Park, Seung‐seob Kim, Kyunghwa Han, Hee Seung Lee, Seungmin Bang, Ho Kyoung Hwang, Sang Hyun Hwang, Mijin Yun, Myeong‐Jin Kim
SJR Q1Scientific ReportsOA

Abstract The objective of this study was to evaluate the role of regional lymph node (LN) metastasis detected on preoperative CT and/or 18 F-fluoro-2-deoxyglucose-positron emission tomography (FDG-PET) scans in the prediction of early tumor recurrence after curative surgical resection of pancreatic ductal adenocarcinoma (PDAC). This retrospective study included 137 patients who underwent upfront surgery with R0 resection of PDAC between 2013 and 2016. Regional LN metastasis was identified using

OncologyMedicine
11
Article|11 citations·2020
Strap muscle invasion in differentiated thyroid cancer does not impact disease-specific survival: a population-based study
Ja Kyung Yoon, Jandee Lee, Eun‐Kyung Kim, Jung Hyun Yoon, Vivian Youngjean Park, Kyunghwa Han, Jin Young Kwak
SJR Q1Scientific ReportsOA

TNM staging system of differentiated thyroid cancer defines gross strap muscle invasion as T3b stage. However, the impact of strap muscle invasion on disease-specific survival (DSS) remains controversial. To elucidate the survival impact of strap muscle invasion of any degree in thyroid cancers, the Surveillance, Epidemiology, and End Results (SEER) database (1973-2018) was queried for thyroid cancer only patients on July 2019 (n = 19,914). The Cox proportional hazard analysis with multivariable

Endocrinology, Diabetes and MetabolismMedicine
12
Article|10 citations·2017
Mesocaval Shunt Creation for Jejunal Variceal Bleeding with Chronic Portal Vein Thrombosis
Ja Kyung Yoon, Man Deuk Kim, Do Yun Lee, Seok Joo Han
SJR Q2Yonsei Medical JournalOA

The creation of transjugular intrahepatic portosystemic shunt (TIPS) is a widely performed technique to relieve portal hypertension, and to manage recurrent variceal bleeding and refractory ascites in patients where medical and/or endoscopic treatments have failed. However, portosystemic shunt creation can be challenging in the presence of chronic portal vein occlusion. In this case report, we describe a minimally invasive endovascular mesocaval shunt creation with transsplenic approach for the

HepatologyMedicine
13
Article|10 citations·2024
Chip collection of hepatocellular carcinoma based on O2 heterogeneity from patient tissue
Sewoom Baek, Hyun‐Su Ha, Jeong Su Park, M CHO, Hye-Seon Kim, Seung Eun Yu, Seyong Chung, Chansik Kim, J. W. Kim, Ji Youn Lee, Yerin Lee, Hyun-Jae Kim
SJR Q1Nature CommunicationsOA

Hepatocellular carcinoma frequently recurs after surgery, necessitating personalized clinical approaches based on tumor avatar models. However, location-dependent oxygen concentrations resulting from the dual hepatic vascular supply drive the inherent heterogeneity of the tumor microenvironment, which presents challenges in developing an avatar model. In this study, tissue samples from 12 patients with hepatocellular carcinoma are cultured directly on a chip and separated based on preference of

Biomedical EngineeringEngineering
14
Review|9 citations·2023
Diagnostic Performance of the 2018 EASL vs. LI‐RADS for Hepatocellular Carcinoma Using CT and MRI: A Systematic Review and Meta‐Analysis of Comparative Studies
Jaeseung Shin, Sunyoung Lee, Ja Kyung Yoon, Yun Ho Roh
SJR Q1Journal of Magnetic Resonance ImagingOA

BACKGROUND: Hepatocellular carcinoma (HCC) can be diagnosed without pathologic confirmation in high-risk patients. Therefore, it is necessary to compare current imaging criteria for noninvasive-diagnosis of HCC. PURPOSE: To systematically compare performance of 2018 European Association for the Study of the Liver (EASL) criteria and Liver Imaging Reporting and Data System (LI-RADS) for noninvasive-diagnosis of HCC. STUDY TYPE: Systematic review and meta-analysis. SUBJECTS: Eight studies with 223

HepatologyMedicine
15
Article|9 citations·2025
Application of LI-RADS CT/MRI Radiation Treatment Response Assessment Version 2024: a study after transarterial radioembolization for hepatocellular carcinoma
Jaeseung Shin, Sunyoung Lee, Ja Kyung Yoon, Kyowon Gu, Sun‐Young Baek, Dongho Hyun, Gyoung Min Kim, Jong Yun Won
SJR Q2Japanese Journal of Radiology
HepatologyMedicine

Research Areas

HepatologyEpidemiologyRadiology, Nuclear Medicine and ImagingSurgeryPhysiologyEndocrinology, Diabetes and Metabolism

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