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Jae Chul Koo

Sungkyunkwan University · Engineering

About the Lab

Professor Jae Chul Koo's research lab focuses on plant molecular biology, particularly on host-defense mechanisms and stress responses in plants, with a strong emphasis on antimicrobial peptides, reactive oxygen species signaling, and viral resistance through genetic engineering. The lab also explores bio-inspired soft robotics for adaptive grasping and develops innovative biomedical technologies, including portable and flexible diagnostic systems for clinical applications. Their interdisciplinary work bridges plant biology, synthetic biology, biomedical engineering, and smart materials.

plant defenseantimicrobial peptidesreactive oxygen speciessoft roboticsportable diagnostics

Research Overview

Papers
404
Total Citations
5,787
Papers (5y)
53
Primary Field
Engineering

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
53total
2021
2022
2023
2024
2025
Citations per year (5y)
272total
20212022202320242025

Selected Papers

15
1
Article|166 citations·1998
Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent antifungal activity
Ja Choon Koo, So Young Lee, Hyun Jin Chun, Yong Hwa Cheong, Jae Su Choi, Shun‐ichiro Kawabata, Masaru Miyagi, Susumu Tsunasawa, Kwon‐Soo Ha, Dong Won Bae, Chang‐deok Han, Bok Luel Lee
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
Article|89 citations·2002
Over-expression of a seed specific hevein-like antimicrobial peptide from Pharbitis nil enhances resistance to a fungal pathogen in transgenic tobacco plants
Ja Choon Koo, Hyun Jin Chun, Hyeong Cheol Park, Min Chul Kim, Yoon Duck Koo, Seong Cheol Koo, Hyun Mi Ok, Soo-Jeong Park, Sung‐Ho Lee, Dae‐Jin Yun, Chae Oh Lim, Jeong Dong Bahk
SJR Q1Plant Molecular Biology
MicrobiologyImmunology and Microbiology
3
Article|65 citations·2004
Ecdysone agonist‐inducible expression of a coat protein gene from tobacco mosaic virus confers viral resistance in transgenic Arabidopsis
Ja Choon Koo, Sebastián Asurmendi, Jennifer Bick, Terry Woodford‐Thomas, Roger N. Beachy
SJR Q1The Plant Journal

Constitutive expression of a gene encoding tobacco mosaic virus (TMV) coat protein (CP) in transgenic plants confers resistance to infection by TMV and related tobamoviruses. Here, we examined resistance to TMV by temporal and quantitative control of TMV Cg CP (CgCP) gene expression using a simple, methoxyfenozide-inducible system in Arabidopsis plants. By soil drenching with a commercial ecdysone agonist (Intrepid-2F/methoxyfenozide), most transgenic lines were induced from undetectable levels

Plant ScienceAgricultural and Biological Sciences
4
Article|62 citations·2004
Pn-AMP1, a Plant Defense Protein, Induces Actin Depolarization in Yeasts
Ja Choon Koo, Bo‐Young Lee, Michael Young, Sung Chul Koo, John A. Cooper, Dongwon Baek, Chae Oh Lim, Sang Yeol Lee, Dae‐Jin Yun, Moo Je Cho
SJR Q1Plant and Cell PhysiologyOA

Pn-AMP1, Pharbitis nil antimicrobial peptide 1, is a small cysteine-rich peptide implicated in host-plant defense. We show here that Pn-AMP1 causes depolarization of the actin cytoskeleton in Saccharomyces cerevisiae and Candida albicans. Pn-AMP1 induces rapid depolarization of actin cables and patches within 15 min. Increased osmolarity or temperature induces transient actin depolarization and results in increased sensitivity to Pn-AMP1, while cells conditioned to these stresses show less sensi

Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
Article|43 citations·2011
Molecular Analysis of Anthocyanin Biosynthetic Genes and Control of Flower Coloration by Flavonoid 3′,5′-Hydroxylase (F3′5′H) in Dendrobium moniliforme
Sung Soo Whang, Wan Sook Um, In-Ja Song, Pyung Ok Lim, Kyung Choi, Kwang-Woo Park, Kyung‐Won Kang, Mi Sun Choi, Ja Choon Koo
SJR Q2Journal of Plant Biology
Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
Article|30 citations·2017
The Protein Trio RPK1–CaM4–RbohF Mediates Transient Superoxide Production to Trigger Age-Dependent Cell Death in Arabidopsis
Ja Choon Koo, In Chul Lee, Cheng Dai, Yuree Lee, Hui Kyung Cho, Yumi Kim, Bong‐Kwan Phee, Hyunmin Kim, Il Hwan Lee, Seung Hee Choi, Su Jin Park, In Seon Jeon
SJR Q1Cell ReportsOA

Reactive oxygen species (ROS) are inevitable by-products of aerobic metabolic processes, causing non-specific oxidative damage and also acting as second messengers. Superoxide is a short-lived ROS that functions in various cellular responses, including aging and cell death. However, it is unclear as to how superoxide brings about age-dependent cell death and senescence. Here, we show that the accumulation and signaling of superoxide are mediated by three Arabidopsis proteins-RPK1, CaM4, and Rboh

Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
Article|25 citations·2021
A Multi-Curvature, Variable Stiffness Soft Gripper for Enhanced Grasping Operations
Eun Jeong Song, Jung Soo Lee, Hyungpil Moon, Hyouk Ryeol Choi, Ja Choon Koo
SJR Q2ActuatorsOA

For soft grippers to be applied in atypical industrial environments, they must conform to an object’s exterior shape and momentarily change their stiffness. However, many of the existing grippers have limitations with respect to these functions: they grasp an object with only a single curvature and a fixed stiffness. Consequently, those constraints limit the stability of grasping and the applications. This paper introduces a new multicurvature, variable-stiffness soft gripper. Inspired by the hu

Biomedical EngineeringEngineering
8
Article|21 citations·2000
Discrete Hamilton's equations for arbitrary Lagrangian–Eulerian dynamics of viscous compressible flow
Ja Choon Koo, Eric P. Fahrenthold
SJR Q1Computer Methods in Applied Mechanics and Engineering
Computational MechanicsEngineering
9
Article|13 citations·2009
Development of an Improved Scheduling Algorithm for Lab Test Operations on a Small-Size Bio Robot Platform
Seung Hoon Shin, Byung June Choi, S.M. Ryew, Jung Ho Kim, Dae Shick Kim, Wan Kyun Chung, Hyouk Ryeol Choi, Ja Choon Koo
JALA Journal of the Association for Laboratory Automation

Blood tests are one of the core processes in the clinical laboratory test field. In hospitals, an automated process called total laboratory automation (TLA), which relies on a set of sophisticated equipment, is normally adopted for the tests. Noting that the TLA system typically has a large footprint and requires a significant amount of power, slim, and easy-to-move blood test equipment is necessary for some specific demands such as emergency rooms or small-size local clinics. Although various p

Biomedical EngineeringEngineering
10
Article|11 citations·2020
A novel variable stiffness scotch yoke series elastic actuator for enhanced functional stiffness
Seung Ho Lee, Hyuk Jin Lee, Kyeong Ha Lee, K. T. Nam, Ja Choon Koo
SJR Q3Microsystem Technologies
Biomedical EngineeringEngineering
11
Article|10 citations·2013
Optimization of high speed EMU suspension parameters for vibration reduction
Seung-Guk Baek, Bum-Sik Shin, Sang Won Lee, Yeon-Sun Choi, Jinhyun Kim, Ja Choon Koo
SJR Q2Journal of Mechanical Science and Technology
Mechanical EngineeringEngineering
12
Article|10 citations·2016
Experimental study of electro-hydraulic actuator with payload for precision motion control
Seung Guk Baek, Sang-Hoon Ji, Ja Choon Koo
SJR Q3Microsystem Technologies
Mechanical EngineeringEngineering
13
Article|10 citations·2007
Representation of a Conceptual Design for a Rectilinear Motion Polymer Actuator
Ja Choon Koo, Kwang Mok Jung, Jong Kil Park, Jae Do Nam, Youngkwan Lee, Jae Wook Jeon, Hyouk Ryeol Choi
SJR Q2International Journal of Control Automation and Systems
Biomedical EngineeringEngineering
14
Article|9 citations·2020
A Non-Array Type Cut to Shape Soft Slip Detection Sensor Applicable to Arbitrary Surface
Sung Joon Kim, Seung Ho Lee, Hyungpil Moon, Hyouk Ryeol Choi, Ja Choon Koo
SJR Q1SensorsOA

The presence of a tactile sensor is essential to hold an object and manipulate it without damage. The tactile information helps determine whether an object is stably held. If a tactile sensor is installed at wherever the robot and the object touch, the robot could interact with more objects. In this paper, a skin type slip sensor that can be attached to the surface of a robot with various curvatures is presented. A simple mechanical sensor structure enables the cut and fit of the sensor accordin

Biomedical EngineeringEngineering
15
Article|9 citations·2018
Feedforward model-inverse position control of three-stage servo-valve using zero magnitude error tracking control
Kyeong Ha Lee, Seung Guk Baek, Hyouk Ryeol Choi, Hyungpil Moon, Sang-Hoon Ji, Ja Choon Koo
SJR Q2Proceedings of the Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science

Three-stage servo-valves are popularly used in hydraulic systems that require large flow rate and high pressure. For a proper control of flow direction and flow rate fed into a hydraulic actuator, securing a proper position control bandwidth is a critical task for the servo-valve. In this paper, a set of popular control methods are systematically studied and a control method is selected. It is proven that the feedforward model-inverse control is the most effective method in terms of the control

Mechanical EngineeringEngineering

Research Areas

Biomedical EngineeringMechanical EngineeringControl and Systems EngineeringCognitive NeuroscienceMolecular BiologyComputational Mechanics

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