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Jae Hwa Cho

Yonsei University · Medicine

About the Lab

Professor Jae Hwa Cho's research lab specializes in respiratory and critical care medicine, with a focus on interstitial lung diseases, pneumothorax, and pulmonary complications in systemic autoimmune conditions. The lab investigates the clinical management and outcomes of patients with acute respiratory conditions such as pulmonary embolism and influenza A/H1N1, particularly in intensive care settings. It also explores molecular mechanisms in gastric carcinoma, especially p53 mutations and their implications in tumor heterogeneity and invasiveness. The lab integrates clinical epidemiology with molecular pathology to improve diagnostic and therapeutic strategies in pulmonary and critical care medicine.

pulmonary embolisminterstitial lung diseasepneumothoraxinfluenza A/H1N1p53 mutation

Research Overview

Papers
282
Total Citations
2,364
Papers (5y)
47
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
47total
2021
2022
2023
2024
2025
Citations per year (5y)
310total
20212022202320242025

Selected Papers

15
1
Review|56 citations·2014
Pneumothorax
Jae Hwa Cho
SJR Q2Tuberculosis & respiratory diseasesOA

Pneumothorax-either spontaneous or iatrogenic-is commonly encountered in pulmonary medicine. While secondary pneumothorax is caused by an underlying pulmonary disease, the spontaneous type occurs in healthy individuals without obvious cause. The British Thoracic Society (BTS, 2010) and the American College of Chest Physicians (ACCP, 2001) published the guidelines for pneumothorax management. This review compares the diagnostic and management recommendations between the two societies. Patients di

Pulmonary and Respiratory MedicineMedicine
2
Article|21 citations·2019
Lung Cancer development and mortality in interstitial lung disease with and without connective tissue diseases: a five-year Nationwide population-based study
Jae Hwa Cho, Dong Yoon Lee, Hyun-Gi Choi, Choong Won Lee
SJR Q1Respiratory ResearchOA

BACKGROUND: Connective tissue disease associated with interstitial lung disease (CTD-ILD) and interstitial lung disease (ILD) alone have same pathological and imaging backgrounds. However, the differences between lung cancer development and the mortality risk between these two conditions are unclear. Incidence of primary lung cancer and all-cause mortality were studied between interstitial lung disease patients with and without connective tissue disease. METHODS: Data were extracted from the Kor

Pulmonary and Respiratory MedicineMedicine
3
Article|14 citations·2005
Inhaled nitric oxide improves the survival of the paraquat-injured rats
Jae Hwa Cho, Doo Kyung Yang, Lucia Kim, Jeong‐Seon Ryu, Hong Lyeol Lee, Chae Man Lim, Youn Suck Koh
SJR Q2Vascular Pharmacology
SurgeryMedicine
4
Article|14 citations·1994
Analysis of regional differences of p53 mutation in advanced gastric carcinoma: relation to heterogeneous differentiation and invasiveness.
Jae Hwa Cho, Masayuki Noguchi, Atsushi Ochiai, S. Uchino, S Hirohashi
PubMed

In order to examine the correlation of p53 mutation with heterogeneous histological differentiation and invasiveness of gastric carcinoma, we analyzed 46 areas (three to six per case) that were different histologically and anatomically in 12 advanced gastric carcinomas, shown previously to be positive for p53 mutation, using immunohistochemical, polymerase chain reaction-single strand conformation polymorphism, and direct DNA sequencing analyses. DNA derived from different sites in nine cases ha

OncologyMedicine
5
Article|13 citations·2010
Estimated Incidence of Acute Pulmonary Embolism in a Korean Hospital
Jae Hwa Cho, Mi‐Young Lee, Doyeun Oh, Byung Hak Rho, Charles A. Hales
SJR Q2Clinical and Applied Thrombosis/HemostasisOA

Patients with acute pulmonary embolism (PE) were identified retrospectively from patients hospitalized during a 2-year period from 2005 to 2007. Among adult patients (≥20 years), the incidence of established acute PE was 88 (0.17%) of 50 882 in Dongsan Hospital. The incidence of acute PE at Dongsan Hospital was 26% lower than that at Henry Ford Hospital (P < .01). Among patients more than 50 years of age, PE was more frequent in women (0.32%; 95% CI, 0.24-0.4) than in men (0.15%; 95% CI, 0.1-0.2

Internal MedicineMedicine
6
Article|10 citations·2014
Small Airway-Centered Granulomatosis Caused by Long-term Exposure to Polytetrafluoroethylene
Jae Hwa Cho, Hye Ra Jung, Esmeralda Shehu, Byung Hak Rho, Mi‐Young Lee, Kun Young Kwon
SJR Q1CHEST JournalOA
Public Health, Environmental and Occupational HealthMedicine
7
Article|9 citations·2012
Immune responses in the lungs of patients with tuberculous pleural effusion without pulmonary tuberculosis
Diana Qama, Jae Hwa Cho, Kun Young Kwon
SJR Q3BMC ImmunologyOA

BACKGROUND: Tuberculous pleural effusion (TPE) is one of the most common forms of extrapulmonary tuberculosis. Because most studies of TPE focused on the pleural space, little information regarding lung parenchyma is available. We therefore aimed to investigate immune responses in the lung parenchyma of TPE patients without pulmonary tuberculosis. METHODS: Patients with any evidence of pulmonary tuberculosis, either from radiologic or bacteriologic evaluation, were excluded. Bronchoalveolar lava

Pulmonary and Respiratory MedicineMedicine
8
Article|7 citations·2012
Structure of Intensive Care Unit and Clinical Outcomes in Critically Ill Patients with Influenza A/H1N1 2009
Jae Hwa Cho, Hun Jae Lee, Sang‐Bum Hong, Gee Young Suh, Moo Suk Park, Seok Chan Kim, Sang Hyun Kwak, Myung Goo Lee, Jae Min Lim, Huyn-Kyung Lee, Younsuck Koh, The Korean Society of Critical Care Medicine H1N1 Collaborative
The Korean Journal of Critical Care Medicine

BACKGROUNDDuring 2009 pandemic period, many Koreans were infected and admitted with Influenza A/H1N1. The primary aim of this study was to evaluate whether the structures of an intensive care unit (ICU) were associated with the outcomes of critically ill patients.METHODSThis retrospective observational study examined critically ill adult patients with influenza A/H1N1, who were admitted to 24 hospitals in Korea, from September 2009 to February 2010. We collected data of ICU structure, patients a

EpidemiologyMedicine
9
Article|7 citations·2006
Spinal Cavernous Hemangioma Causing Sudden Paraplegia in a 23-Month-Old Kid.
Jae Hwa Cho, Chung Yn, Wang Kc, B K Cho
SJR Q2Journal of Korean Neurosurgical SocietyOA
NeurologyMedicine
10
Article|6 citations·2010
Influence of Trap Type and Location on Tree Trunk on Platypus koryoensis (Coleoptera: Platypodidae) Trapping
Jun-Heon Kim, Jung‐Su Lee, Il‐Kwon Park, Jae Hwa Cho
Korean journal of applied entomologyOA

참나무시들음병 매개충인 광릉긴나무좀 (Platypus koryoensis (Murayama)) (Coleoptera: Platypodidae) 모니터링에 활용 가능한 트랩 종류, 색, 설치위치가 포획수에 미치는 영향이 조사되었다. 조사는 경기도 파주시 광탄면에서 수행되었으며 끈끈이 평판 트랩과 다중깔때기 트랩 두 종류 트랩이 이용되었다. 조사된 두 트랩의 종류는 광릉긴나무좀 포획수에 영향을 미치지 않았다. 끈끈이 평판 트랩의 경우 노란색, 검정색, 흰색, 투명색으로 시험한 결과 트랩색이 광릉긴나무좀 포획효율에 영향을 미치지 않았다. 끈끈이 평판 트랩과 다중깔때기 트랩 모두 수간내 경사 위쪽과 아래쪽에 설치된 경우, 산의 경사 위쪽에 설치한 트랩에 유의하게 많은 수의 광릉긴나무좀이 포획되었다. 이는 두 가지 트랩이 모두 광릉긴나무좀 모니터링 및 방제에 효율적으로 활용될 수 있음을 보여주는 것이다. Differences in the number of Platypus koryoensis

EcologyEnvironmental Science
11
Article|5 citations·1999
Chronic cough: the spectrum and the frequency of etiologies
Jae Hwa Cho, Jeong‐Seon Ryu, Hong Lyeol Lee
SJR Q2Tuberculosis and Respiratory DiseasesOA

BACKGROUND: Chronic cough is a common symptom that requires the systematic diagnostic approach for proper evaluation. Postnasal drip syndrome(PNDS), bronchial asthma, gastroesophageal reflux disease(GERD), and chronic bronchitis are among the common causes. This study was conducted to evaluate the spectrum and the frequency of the causes of chronic cough. METHODS: We prospectively evaluated 93 patients who had chronic cough despite normal chest radiographic finding. History and physical examinat

Pulmonary and Respiratory MedicineMedicine
12
Article|5 citations·2009
A Pulmonary Nodule due to Pulmonary Infarction Diagnosed by Video-Assisted Thoracoscopy
Jae Hwa Cho, Joung Taek Kim, Lucia Kim, Kyung Hee Lee, Jeong‐Seon Ryu, Seung Min Kwak, Hong Lyeol Lee
SJR Q2Yonsei Medical JournalOA

We report a pulmonary infarction in 68-year-old man who was referred for an asymptomatic pulmonary nodule in chest radiography. Computed tomography (CT), positron emission tomography (PET), and transthoracic needle aspiration suggested suspicion for malignancy. Video-assisted thoracoscopic surgery (VATS) was performed for histologic diagnosis. Our case is a pulmonary nodule due to pulmonary infarction diagnosed by VATS in Korea.

Pulmonary and Respiratory MedicineMedicine
13
Article|5 citations·2006
Acute lung injury caused by ethambutol
Jae Hwa Cho, Young June Jeon, Kun‐Young Kwon, Sung-Min Ko, Dong-Yoon Keum, Chang Kwon Park
Respiratory Medicine Extra
SurgeryMedicine
14
Article|4 citations·2015
Incidence of Chronic Thromboembolic Pulmonary Hypertension after Pulmonary Embolism: A Retrospective Analysis in a University Teaching Hospital
Jae Hwa Cho
Clinical & Experimental Thrombosis and HemostasisOA

Purpose: Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with considerable morbidity and mortality. Its incidence after pulmonary embolism and associated risk factors in the Korean population are not well documented. Methods: A retrospective cohort study was conducted to assess the incidence of symptomatic CTEPH in patients with an acute episode of pulmonary embolism without prior history of venous thromboembolism. Patients experiencing unexplained persistent dyspnea during f

Internal MedicineMedicine
15
Article|3 citations·2006
Hearing Outcome after Gamma Knife Stereotactic Radiosurgery in Vestibular Schwannoma Patients with Serviceable Hearing.
Jae Hwa Cho, Paek Sh, Chung Ht, Jeong Ss, Jung Hw, D G Kim
SJR Q2Journal of Korean Neurosurgical SocietyOA
EpidemiologyMedicine

Research Areas

Pulmonary and Respiratory MedicineEpidemiologySurgeryCritical Care and Intensive Care MedicinePhysiologyInternal Medicine

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