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Jae Min Lee

Korea University · Medicine

About the Lab

Professor Jae Min Lee's research lab specializes in gastrointestinal endoscopy and interventional radiology, focusing on improving diagnostic and therapeutic outcomes for pancreatic and biliary tract diseases. The lab investigates advanced endoscopic techniques such as EUS-FNA with optimized needle manipulation methods, stent-in-stent procedures for malignant biliary obstruction, and endoscopic resection of large colonic tumors. Additionally, the lab explores the role of systemic inflammatory markers in predicting cancer prognosis and evaluates protective strategies against chemotherapy-induced mucosal injury, particularly using trace elements like selenium. The research emphasizes minimally invasive interventions, biomarker applications, and translational approaches to enhance patient outcomes in gastrointestinal oncology and intervention.

endoscopic ultrasoundbiliary stentingchemotherapy-induced mucositispancreatic massselenium supplementation

Research Overview

Papers
292
Total Citations
2,017
Papers (5y)
87
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
87total
2022
2023
2024
2025
2026
Citations per year (5y)
363total
20222023202420252026

Selected Papers

15
1
Article|56 citations·2018
pH-Responsive hyaluronated liposomes for docetaxel delivery
Jae Min Lee, Hongsuk Park, Kyung Taek Oh, Eun Seong Lee
SJR Q1International Journal of Pharmaceutics
BiomaterialsMaterials Science
2
Article|44 citations·2018
Slow-Pull Using a Fanning Technique Is More Useful Than the Standard Suction Technique in EUS-Guided Fine Needle Aspiration in Pancreatic Masses
Jae Min Lee, Hong Sik Lee, Jong Jin Hyun, Jung Min Lee, In Kyung Yoo, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hoon Jai Chun
SJR Q1Gut and LiverOA

BACKGROUND/AIMS: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is useful for obtaining pancreatic mass samples. The combination of modified techniques (i.e., slow-pull technique and fanning technique) may improve the quality of the sample obtained by EUS-FNA. We investigated the effectiveness of a combined slow-pull fanning technique in EUS-FNA for pancreatic mass. METHODS: This prospective comparative study investigated EUS-FNA performed for pancreatic solid masses between Augus

OncologyMedicine
3
Article|34 citations·2016
Prognostic value of inflammation-based markers in patients with pancreatic cancer administered gemcitabine and erlotinib
Jae Min Lee, Hong Sik Lee, Jong Jin Hyun, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim
SJR Q2World Journal of Gastrointestinal OncologyOA

Systemic inflammation-based markers, including increases in the NLR and the CRP/Alb ratio, may be useful for predicting PC prognoses.

OncologyMedicine
4
Article|33 citations·2017
Selenium Administration Attenuates 5-Flurouracil-Induced Intestinal Mucositis
Jae Min Lee, Hoon Jai Chun, Hyuk Soon Choi, Eun Sun Kim, Yeon Seok Seo, Yoon Tae Jeen, Hong Sik Lee, Soon Ho Um, Chul Hwan Kim, Donggeun Sul
SJR Q2Nutrition and Cancer

Chemotherapy-induced mucositis is mediated by the release of proinflammatory cytokines and reactive oxygen species. Selenium has several metabolic functions, including the protection of membrane lipids and macromolecules against oxidative damage. However, to date, there is little evidence on the effect of trace elements on intestinal mucositis after chemotherapy. This study investigated the protective effect of selenium against chemotherapy-induced mucositis in rats. Twenty-four 9-wk-old female

Pulmonary and Respiratory MedicineMedicine
5
Article|30 citations·2018
EUS-guided irreversible electroporation using endoscopic needle-electrode in porcine pancreas
Jae Min Lee, Hyuk Soon Choi, Hoon Jai Chun, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hong Sik Lee, Soon Ho Um, Chang Duck Kim, Hong Bae Kim
SJR Q1Surgical Endoscopy
BiotechnologyBiochemistry, Genetics and Molecular Biology
6
Article|25 citations·2015
Endoscopic submucosal dissection of a large colonic lipoma: Report of two cases
Jae Min Lee
SJR Q1World Journal of GastroenterologyOA

A colonic lipoma is a very rare benign tumor that is usually asymptomatic and is found incidentally by colonoscopy. Patients with a large colonic lipoma may present with symptoms such as abdominal pain, bleeding, and colonic obstruction or intussusceptions. We report two patients with large colonic lipomas and symptoms. Standard endoscopic submucosal dissection (ESD) was performed to remove the lipomas instead of conventional surgical bowel resection. No complications were observed during or aft

SurgeryMedicine
7
Article|25 citations·2015
Small cell‐ versus large cell‐sized metal stent in endoscopic bilateral stent‐in‐stent placement for malignant hilar biliary obstruction
Jae Min Lee, Sang Hyub Lee, Kwang Hyun Chung, Jin Myung Park, Woo Hyun Paik, Sang Myung Woo, Woo Jin Lee, Ji Kon Ryu, Yong‐Tae Kim
SJR Q1Digestive Endoscopy

BACKGROUND AND AIM: Although the large cell-sized biliary stent facilitates contralateral stent deployment through the mesh of the first metallic stent for stent-in-stent (SIS) technique, there are concerns about its vulnerability to tumor ingrowth. The aim of the present study was to compare the clinical outcomes of endoscopic bilateral SIS placement according to the cell size of a self-expandable metallic stent (SEMS). METHODS: A total of 58 patients were enrolled who underwent endoscopic bila

Pulmonary and Respiratory MedicineMedicine
8
Article|25 citations·2018
Is a One Night Delay of Surgery Safe in Patients With Acute Appendicitis?
Jae Min Lee, Beom Seok Kwak, Young Jin Park
SJR Q2Annals of ColoproctologyOA

PURPOSE: With varied reports on the impact of time to appendectomy on clinical outcomes, the purpose of this study was to determine the effect of preoperative in-hospital delay on the outcome for patients with acute appendicitis. METHODS: A retrospective review of 1,076 patients who had undergone an appendectomy between January 2010 and December 2013 was conducted. RESULTS: The outcomes of surgery and the pathologic findings were analyzed according to elapsed time. The overall elapsed time from

Emergency MedicineMedicine
9
Article|23 citations·2016
Usefulness of ascitic fluid lactoferrin levels in patients with liver cirrhosis
Sang Soo Lee, Hyun Ju Min, Ja Yun Choi, Hyun Chin Cho, Jin Joo Kim, Jae Min Lee, Hong Jun Kim, Chang Yoon Ha, Hyun Jin Kim, Tae Hyo Kim, Jin Hyun Kim, Ok‐Jae Lee
SJR Q2BMC GastroenterologyOA

BACKGROUND: Although elevated levels of lactoferrin provide a biomarker for inflammatory bowel diseases and colorectal cancer, the clinical significance of these elevated levels in ascitic fluid of patients with ascites caused by liver cirrhosis is limited. The aims of our study were to investigate the usefulness of ascitic fluid lactoferrin levels for the diagnosis of spontaneous bacterial peritonitis (SBP) in patients with cirrhosis and to evaluate the association between lactoferrin levels an

Nutrition and DieteticsNursing
10
Article|20 citations·2017
Successful access to the ampulla for endoscopic retrograde cholangiopancreatography in patients with situs inversus totalis: a case report
Jung Min Lee, Jae Min Lee, Jong Jin Hyun, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Chang Duck Kim
SJR Q2BMC SurgeryOA

BACKGROUND: Although various endoscopic techniques in situs inversus have been reported, endoscopic retrograde cholangiopancreatography (ERCP) in patients with situs inversus is always challenging even for an experienced endoscopist. We performed ERCP using two different techniques, and compare the merits of each technique. CASE PRESENTATION: A 74-year-old woman presented with epigastric pain and jaundice for 3 days. Computed tomography revealed diffuse dilatation of the biliary tree, with multi

SurgeryMedicine
11
Article|19 citations·2019
Characterization of irreversible electroporation on the stomach: A feasibility study in rats
Jae Min Lee, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim, Hong Bae Kim
SJR Q1Scientific ReportsOA

Irreversible electroporation (IRE) is a newly developed non-thermal ablative therapy. During the IRE procedure, the permeability of the cell membrane is irreversibly changed by application of high-energy pulses across the tissue. This induces the breakdown of cell homeostasis, and thereby cell death. Here, we present an in vivo study to demonstrate IRE ablation of gastric tissue and characterize the changes that occur with time therein. No significant complications were observed in the test rats

BiotechnologyBiochemistry, Genetics and Molecular Biology
12
Review|17 citations·2022
New sedatives and analgesic drugs for gastrointestinal endoscopic procedures
Jae Min Lee, Yehyun Park, Jin Myung Park, Hong Jun Park, Jun Yong Bae, Seung Young Seo, Jee Hyun Lee, Hyung Ku Chon, Jun‐Won Chung, Hyun Ho Choi, Jun Kyu Lee, Byung‐Wook Kim
SJR Q2Clinical EndoscopyOA

Procedural sedation has become increasingly common in endoscopy. Sedatives and analgesics induce anxiolysis and amnesia. In addition, an appropriate level of sedation is necessary for safe procedures including therapeutic endoscopy. Midazolam and propofol are the most commonly used drugs in sedative endoscopy. In recent years, the need to ascertain the safety and effectiveness of sedation has increased in practice. Therefore, new sedatives and analgesic drugs for optimal sedative endoscopy, have

Anesthesiology and Pain MedicineMedicine
13
Article|16 citations·2015
Air cholangiography in endoscopic bilateral stent-in-stent placement of metallic stents for malignant hilar biliary obstruction
Jae Min Lee, Sang Hyub Lee, Dong Kee Jang, Kwang Hyun Chung, Jin Myung Park, Woo Hyun Paik, Jun Kyu Lee, Ji Kon Ryu, Yong‐Tae Kim
SJR Q1Therapeutic Advances in GastroenterologyOA

BACKGROUND: Although endoscopic bilateral stent-in-stent (SIS) placement of self-expandable metallic stents (SEMS) is one of the major palliative treatments for unresectable malignant hilar biliary obstruction, post-endoscopic retrograde cholangiopancreatography (ERCP) cholangitis can occur frequently due to inadequate drainage, especially after contrast injection into the biliary tree. The aim of this study is to evaluate the efficacy and safety of air cholangiography-assisted stenting. METHODS

Pulmonary and Respiratory MedicineMedicine
14
Article|16 citations·2016
Polyethylene glycol plus ascorbic acid for bowel preparation in chronic kidney disease
Jae Min Lee, Bora Keum, In Kyung Yoo, Seung Han Kim, Hyuk Soon Choi, Eun Sun Kim, Yeon Seok Seo, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Soon Ho Um, Chang Duck Kim
SJR Q3MedicineOA

The safety of polyethylene glycol plus ascorbic acid has not been fully investigated in patients with renal insufficiency. High-dose ascorbic acid could induce hyperoxaluria, thereby causing tubule-interstitial nephritis and renal failure. This study aims to evaluate the safety and efficacy of polyethylene glycol plus ascorbic acid in patients with chronic kidney disease.We retrospectively reviewed prospectively collected data on colonoscopy in patients with impaired renal function. Patients wer

OncologyMedicine
15
Article|14 citations·2015
Risk factors of organ failure in cholangitis with bacteriobilia
Jae Min Lee
SJR Q1World Journal of GastroenterologyOA

ESBL organisms in blood cultures, pre-existing renal dysfunction, and choledocholithiasis are risk factors for OF in cholangitis with bacteriobilia. The OF scoring system may aid clinicians to identify a poor prognosis group.

Pulmonary and Respiratory MedicineMedicine

Research Areas

SurgeryOncologyPulmonary and Respiratory MedicineHepatologyBiotechnologyAnesthesiology and Pain Medicine

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