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Jae‐Won Shin

Yonsei University · Medicine

About the Lab

Professor Jae-Won Shin's research lab specializes in minimally invasive and robotic surgical techniques, particularly in colorectal and spinal surgery, with a focus on complex oncologic resections and long-term outcomes. The lab also investigates pharmacokinetics in neonatal populations and the impact of pre-surgical mental health on postoperative recovery. A key emphasis is placed on improving surgical precision, patient safety, and early detection of complications such as metastasis or adjacent segment pathology. The lab integrates advanced imaging, clinical pharmacology, and prospective cohort studies to enhance surgical outcomes and personalized care.

robotic surgeryspinal fusionneonatal pharmacokineticspost-surgical painoncologic resection

Research Overview

Papers
78
Total Citations
760
Papers (5y)
36
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
36total
2022
2023
2024
2025
2026
Citations per year (5y)
77total
20222023202420252026

Selected Papers

15
1
Article|58 citations·2014
Complete mesocolic excision with D3 lymph node dissection in laparoscopic colectomy for stages II and III colon cancer: long-term oncologic outcomes in 168 patients
Jae‐Won Shin, Azali Hafiz Yafee Amar, S. H. Kim, J. M. Kwak, Se Jin Baek, J. S. Cho, J. Kim
SJR Q1Techniques in Coloproctology
OncologyMedicine
2
Article|47 citations·2013
First report: robotic pelvic exenteration for locally advanced rectal cancer
Jae‐Won Shin, J. Kim, J. M. Kwak, Masayasu Hara, Jeong Hyun Cheon, Sanghee Kang, Sookyung Kang, Andrew R. L. Stevenson, Geoff Coughlin, Seon Hahn Kim
SJR Q2Colorectal Disease

AIM: The aim of this study was to present the feasibility and surgical outcome of robotic en bloc resection of the rectum and with prostate and seminal vesicle invaded by rectal cancer. METHOD: The details of three consecutive cases involving male patients in their forties, with locally invasive low rectal cancers are presented. The da Vinci robotic system was used by experienced colorectal and urological surgeons to perform en bloc resection of the rectum, prostate and seminal vesicles. RESULTS

Pulmonary and Respiratory MedicineMedicine
3
Article|14 citations·2017
Experience and pharmacokinetics of Levetiracetam in Korean neonates with neonatal seizures
Jae‐Won Shin, Yun Seob Jung, Kyungsoo Park, Soon Min Lee, Ho Seon Eun, Min Soo Park, Kook In Park, Ran Namgung
Korean Journal of PediatricsOA

PURPOSE: The aims of this study were to evaluate the safety and pharmacokinetics of levetiracetam (LEV) in neonates with seizures and to establish a population pharmacokinetics (PPK) model by using the software NONMEM. METHODS: A retrospective analysis of 18 neonatal patients with seizures, who were treated with LEV, including 151 serum samples, was performed. The mean loading dose was 20 mg/kg, followed by a mean maintenance dose of 29 mg/kg/day. RESULTS: Seventeen neonates (94%) had seizure ce

Pediatrics, Perinatology and Child HealthMedicine
4
Article|6 citations·2022
Comparison of the efficacy between sequential therapy with teriparatide and denosumab and denosumab monotherapy in suppressing fragility fracture risk
Jae‐Won Shin, Quen He, Yong June Suk, Sang-Ho Kim, Hak‐Sun Kim
SJR Q1Osteoporosis InternationalOA
Orthopedics and Sports MedicineMedicine
5
Article|6 citations·2024
Association of Untreated Pre-surgical Depression With Pain and Outcomes After Spinal Surgery
Jae‐Won Shin, Yung Park, Sunghoon Park, Joong Won Ha, Woo-Seok Jung, Hak-Sun Kim, Kyung‐Soo Suk, Si-Young Park, Seong-Hwan Moon, Byung Ho Lee, Ji-Won Kwon, Jaeun Ahn
SJR Q1Global Spine JournalOA

Study DesignProspective Cohort Study.ObjectiveUntreated pre-surgical depression may prolong post-surgical pain and hinder recovery. However, research on the impact of untreated pre-surgical depression on post-spinal surgery pain is lacking. Therefore, this study aimed to assess pre-surgical depression in patients and analyze its relationship with post-surgical pain and overall post-surgical outcomes.MethodsWe recruited 100 patients scheduled for lumbar spine surgery due to spondylolisthesis, deg

Pathology and Forensic MedicineMedicine
6
Article|6 citations·2024
Long-Term Incidence of Adjacent Segmental Pathology After Minimally Invasive vs. Open Transforaminal Lumbar Interbody Fusion
Jae‐Won Shin, Yung Park, Sang-Ho Kim, Sung-Ryul Choi, Joong-Won Ha, Hak‐Sun Kim, Kyung‐Soo Suk, Sung-Hwan Moon, Si-Young Park, Byung Ho Lee, Ji-Won Kwon, Hee-Min Choi
SJR Q1Global Spine JournalOA

Study designRetrospective cohort study.ObjectiveTo compare the incidence of adjacent segmental pathology (ASP) following minimally invasive (MI) vs open transforaminal lumbar interbody fusion (TLIF) and to identify factors linked to ASP requiring reoperation.MethodsThis retrospective study reviewed the outcomes of patients who underwent MI-TLIF or open TLIF. Radiographic ASP (RASP) was evaluated using X-ray imaging to distinguish between degenerative changes, spondylolisthesis, and instability i

Pathology and Forensic MedicineMedicine
7
Article|6 citations·2022
Changes in retro-odontoid mass after upper cervical spine surgery
Jae‐Won Shin, Kyung‐Soo Suk, Hak‐Sun Kim, Jae‐Ho Yang, Hwan‐Mo Lee, Sung-Hwan Moon, Byung Ho Lee, Jin‐Oh Park, Sang-Jun Park, Sub-Ri Park, Sunkyu Kim, Jane F. Garcia
SJR Q1Scientific ReportsOA

A non-neoplastic mass posterior to the dens is termed a retro-odontoid mass (R-OM). This retrospective study evaluated radiographic and clinical outcomes and R-OM changes after upper cervical spine surgery. This study included 69 patients who underwent upper cervical spine surgery, including atlantoaxial fusion, occipitocervical fusion, or decompression. All patients underwent preoperative magnetic resonance imaging (MRI). Six-month follow-up MRI examinations were performed in 30 patients who ha

SurgeryMedicine
8
Article|4 citations·2010
Significance of Follow-up in Detection of Pulmonary Metastasis of Colorectal Cancer
Jae‐Won Shin, Sun Il Lee, Hong Young Moon
Journal of the Korean society of coloproctologyOA

Conventional chest radiography is no more useful in detecting early pulmonary metastasis after a curative colorectal surgery than a routine chest CT. Thus, we propose the use of routine chest CT for screening for lung metastasis.

Pulmonary and Respiratory MedicineMedicine
9
Article|3 citations·2024
Risk Factors and Characteristics of In-Hospital Falls After Spine Surgery
Jae‐Won Shin, Heon Jung Park, Yung Park, Joong Won Ha, Jung Hwa Hong, Hak‐Sun Kim, Kyung‐Soo Suk, Seong-Hwan Moon, Si-Young Park, Byung Ho Lee, Ji-Won Kwon
SJR Q1JBJS Open AccessOA

Background: Falls after orthopaedic surgery can cause serious injuries, which lengthen hospital stays and increase medical expenses. This has prompted hospitals to implement various fall-prevention protocols. The aims of this study were to determine the incidence of in-hospital falls after spine surgery, to analyze the overall risk factors, to discern factors that have a major influence on falls, and to evaluate the effectiveness of the fall-prevention protocol that we implemented. Methods: This

Physical Therapy, Sports Therapy and RehabilitationHealth Professions
10
Article|3 citations·2022
Direct Internal Fixation for Unstable Atlas Fractures
Jae‐Won Shin, Kyung‐Soo Suk, Hak‐Sun Kim, Jae‐Ho Yang, Ji-Won Kwon, Hwan‐Mo Lee, Sung-Hwan Moon, Byung Ho Lee, Sang-Jun Park, Sub-Ri Park, Sunkyu Kim
SJR Q2Yonsei Medical JournalOA

C1 motion-preserving direct internal fixation technique results in good reduction and stabilization of unstable atlas fractures. This technique allows for the preservation of craniocervical and atlantoaxial motion.

SurgeryMedicine
11
Article|1 citations·2020
Posterior Device Fixation Using Pedicle Screws in Patients with Degenerative Spine Disease: A Prospective, Single-Group, Therapeutic Pilot Study
Jae‐Won Shin, Sub-Ri Park, Sunkyu Kim, Hak-Sun Kim
SJR Q4Journal of Korean society of spine surgeryOA

Study Design: Prospective study

SurgeryMedicine
12
Article|1 citations·2025
Biomechanical Effects of Cement Augmentation and Prophylactic Vertebroplasty on Adjacent Segment Stability in Multilevel Spinal Fusion: A Finite Element Analysis
Jae‐Won Shin, Dae Hyeon Kim, Ki Mun Kang, Tae Hyun Park, Young‐Jei Oh, Sung Jae Lee, Byung Ho Lee
SJR Q2BioengineeringOA

BACKGROUND: Multilevel posterior spinal fusion to T10 often encounters complications such as screw loosening and proximal junctional kyphosis. Cement augmentation or prophylactic vertebroplasty is used to prevent these, but their biomechanical effects remain unclear. METHODS: A validated finite element model (T8-pelvis) from CT data of a 57-year-old male was tested in five configurations: fusion only, fusion with cement augmentation at T10, T10-T11, T10-T11 plus T9 vertebroplasty, and T10-T11 pl

SurgeryMedicine
13
Article|1 citations·2019
A Study on Improvement of the Abnormal Operation of a One-shot Rifle with Bolt-action Operating System
Jae‐Won Shin, Chan Man Jung, Si Young Choi, Ho Jun Lee, Tae Sung Shin, Hyun Su Seo
Journal of the Korean society for quality managementOA

Purpose: In this study, the goal is to analyze this case to prevent the same accidents when using one-shot rifle.Methods: Detailed analysis of damaged parts must first be made in order to determine the cause of the abnormal explosion. The cause of abnormal operation can be determined by analyzing the information of damaged components and the firing mechanism of the weapon step by step. Also we can refer to a statement of shooter, witness and accident scene situation. Based on this theory, cause

Pulmonary and Respiratory MedicineMedicine
14
Article|1 citations·2025
Mitofusin 1 in mitochondrial quality control and anti-inflammatory responses in nucleus pulposus cells during disc degeneration
Jae‐Won Shin, Young Mi Kang, Hak‐Sun Kim, Seong-Hwan Moon, Kyung‐Soo Suk, So Yeon Park, Byung Ho Lee, Ji-Won Kwon
SJR Q1Scientific ReportsOA

Mitochondrial dysfunction drives intervertebral disc degeneration, and mitochondrial dynamics are regulated by mitofusins (MFNs). In this study, we evaluated the roles of MFN1 and MFN2 in mitochondrial quality control and their responses to inflammation and antioxidant treatment in grade I and III disc nucleus pulposus cells (NPCs). Human NPCs were isolated from intervertebral disc tissues of patients. Tumor necrosis factor-α (TNF-α)-induced inflammation was treated with vitamin E (Vit E) or sap

Pathology and Forensic MedicineMedicine
15
Article|1 citations·2023
Subdural hygroma as a rare complication after revision spine surgery
Yung Park, Chang‐Min Lee, Joong Won Ha, Jae‐Won Shin
SJR Q4BMJ Case ReportsOA

Spinal fusion surgery is the most commonly performed orthopaedic surgical procedure. However, subdural hygroma occurrence is a very rare complication after revision spinal fusion surgery. Here, we report a case of revision lumbar fusion surgery at the L3-4 level. The patient developed acute conus medullaris syndrome at 10 days postoperatively. MRI showed a subdural, extra-arachnoid area fluid collection following the T12-L2, cephalad to the area of revision spinal fusion. When patients have a de

Public Health, Environmental and Occupational HealthMedicine

Research Areas

SurgeryPathology and Forensic MedicineOncologyPulmonary and Respiratory MedicineOrthopedics and Sports MedicinePublic Health, Environmental and Occupational Health

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