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Jaeyeong Kim

Yonsei University · Medicine

About the Lab

Professor Jaeyeong Kim's research lab specializes in developing advanced biomedical technologies that bridge artificial intelligence, molecular engineering, and clinical diagnostics. The lab focuses on creating deep learning-based diagnostic systems for medical imaging—particularly in dentistry and orthopedics—while also pioneering innovative protein engineering platforms for antibody purification and immunoassays. Their work emphasizes clinical translation, integrating machine learning with biological specificity to improve disease detection and therapeutic development.

deep learningbiomedical imagingprotein engineeringantibody purificationmedical diagnostics

Research Overview

Papers
460
Total Citations
6,431
Papers (5y)
95
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
95total
2022
2023
2024
2025
2026
Citations per year (5y)
367total
20222023202420252026

Selected Papers

15
1
Article|234 citations·2019
DeNTNet: Deep Neural Transfer Network for the detection of periodontal bone loss using panoramic dental radiographs
Jae‐Young Kim, Hong-Seok Lee, In‐Seok Song, Kyu-Hwan Jung
SJR Q1Scientific ReportsOA

In this study, a deep learning-based method for developing an automated diagnostic support system that detects periodontal bone loss in the panoramic dental radiographs is proposed. The presented method called DeNTNet not only detects lesions but also provides the corresponding teeth numbers of the lesion according to dental federation notation. DeNTNet applies deep convolutional neural networks(CNNs) using transfer learning and clinical prior knowledge to overcome the morphological variation of

Oral SurgeryDentistry
2
Article|179 citations·2008
Engineered Bacterial Outer Membrane Vesicles with Enhanced Functionality
Jae‐Young Kim, Anne M. Doody, David J. Chen, Gina H. Cremona, Michael L. Shuler, David Putnam, Matthew P. DeLisa
SJR Q1Journal of Molecular Biology
MicrobiologyImmunology and Microbiology
3
Article|90 citations·2013
A simple classification of facial asymmetry by TML system
Jae‐Young Kim, Hwi-Dong Jung, Young‐Soo Jung, Chung–Ju Hwang, Hyung-Sik Park
SJR Q1Journal of Cranio-Maxillofacial SurgeryOA
OrthodonticsDentistry
4
Article|67 citations·2008
Socioeconomic Disparities in Breast Cancer Screening among US Women: Trends from 2000 to 2005
Jae‐Young Kim, Soong‐Nang Jang
SJR Q2Journal of Preventive Medicine and Public HealthOA

These findings suggest that the trend of the disparity in breast cancer screening varied by socioeconomic dimension. Continued differences in breast cancer screening rates related to income level should be considered in future efforts to decrease the disparities in breast cancer among socioeconomic groups. More focused interventions, as well as the monitoring of trends in cancer screening participation by income and education, are needed in different social settings.

OncologyMedicine
5
Article|57 citations·2005
Genetically Engineered Elastin-Protein A Fusion as a Universal Platform for Homogeneous, Phase-separation Immunoassay
Jae‐Young Kim, Sean O’Malley, Ashok Mulchandani, Wilfred Chen
SJR Q1Analytical Chemistry

A simple and universal platform for competitive phase-separation immunoassay is reported based on a fusion protein composed of a temperature-responsive elastin-like polypeptide (ELP) and the antibody-binding staphylococcal protein A (SpA). The basic principle is to take advantage of the ability of SpA to bind a variety of antibodies with high affinity, allowing simple separation of antigen-antibody complex by thermal precipitation. The resulting ELP-SpA fusion was shown to preserve the ability t

GeneticsBiochemistry, Genetics and Molecular Biology
6
Article|50 citations·2005
Temperature‐triggered purification of antibodies
Jae‐Young Kim, Ashok Mulchandani, Wilfred Chen
SJR Q2Biotechnology and Bioengineering

In this article the unique capability of elastin-like protein (ELP) to reversibly precipitate was combined with the high affinity and specificity of antibody-binding domains such as Protein G, Protein L, or Protein LG as a general method for antibody purification that combines in a unique manner the simplicity and robustness of temperature-triggered precipitation with the selectivity of affinity interactions. In a single precipitation step, antibodies derived from different sources (animal sera

Radiology, Nuclear Medicine and ImagingMedicine
7
Article|45 citations·2016
Comparison of volume and position of the temporomandibular joint structures in patients with mandibular asymmetry
Jae‐Young Kim, Bum-Joon Kim, Kwang‐Ho Park, Jong‐Ki Huh
SJR Q2Oral Surgery Oral Medicine Oral Pathology and Oral RadiologyOA
OrthodonticsDentistry
8
Article|42 citations·2008
Shh and ROCK1 modulate the dynamic epithelial morphogenesis in circumvallate papilla development
Jae‐Young Kim, Min-Jung Lee, Kyoung‐Won Cho, Jong‐Min Lee, Yeun-Jung Kim, Ji‐Youn Kim, Hye-In Jung, Hye-In Jung, Je-Yoel Cho, Sung Won Cho, Han-Sung Jung, Han-Sung Jung
SJR Q2Developmental BiologyOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
Article|42 citations·2003
Morphological evidence of the importance of epithelial tissue during mouse tongue development
Jae‐Young Kim, Tomoyuki Mochizuki, Keiichi Akita, Han‐Sung Jung
SJR Q2Experimental Cell ResearchOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
Article|41 citations·2021
Using deep learning to predict temporomandibular joint disc perforation based on magnetic resonance imaging
Jae‐Young Kim, Dong Wook Kim, Kug Jin Jeon, Hwiyoung Kim, Jong‐Ki Huh
SJR Q1Scientific ReportsOA

The goal of this study was to develop a deep learning-based algorithm to predict temporomandibular joint (TMJ) disc perforation based on the findings of magnetic resonance imaging (MRI) and to validate its performance through comparison with previously reported results. The study objects were obtained by reviewing medical records from January 2005 to June 2018. 299 joints from 289 patients were divided into perforated and non-perforated groups based on the existence of disc perforation confirmed

Complementary and Manual TherapyHealth Professions
11
Article|40 citations·2023
Explainable deep learning-based clinical decision support engine for MRI-based automated diagnosis of temporomandibular joint anterior disk displacement
Kyubaek Yoon, Jae‐Young Kim, Jae‐Young Kim, Sun‐Jong Kim, Jong‐Ki Huh, Jin‐Woo Kim
SJR Q1Computer Methods and Programs in BiomedicineOA
Complementary and Manual TherapyHealth Professions
12
Article|37 citations·2005
Twin-Arginine Translocation of Active Human Tissue Plasminogen Activator in Escherichia coli
Jae‐Young Kim, Elizabeth A. Fogarty, Franklin J. Lu, Hui Zhu, Geoffrey D. Wheelock, Lee A. Henderson, Matthew P. DeLisa
SJR Q1Applied and Environmental MicrobiologyOA

When eukaryotic proteins with multiple disulfide bonds are expressed at high levels in Escherichia coli, the efficiency of thiol oxidation and isomerization is typically not sufficient to yield soluble products with native structures. Even when such proteins are secreted into the oxidizing periplasm or expressed in the cytoplasm of cells carrying mutations in the major intracellular disulfide bond reduction systems (e.g., trxB gor mutants), correct folding can be problematic unless a folding mod

Cell BiologyBiochemistry, Genetics and Molecular Biology
13
Article|37 citations·2014
Clinical, Functional, and Morphological Evaluations of Posterior Cruciate Ligament Reconstruction With Remnant Preservation
Dhong Won Lee, Hyoung Won Jang, Yong Seuk Lee, Soo Jin Oh, Jae‐Young Kim, Jae‐Young Kim, Han Eui Song, Jin Goo Kim, Jin Goo Kim
SJR Q1The American Journal of Sports Medicine

BACKGROUND: Numerous posterior cruciate ligament (PCL) reconstruction techniques have evolved and have revealed satisfactory outcomes; however, the optimal operative method for PCL reconstruction remains controversial. HYPOTHESIS: Transtibial PCL reconstruction with a remnant preservation technique would result in successful clinical, radiological, functional, and morphological outcomes. In addition, it was hypothesized that the results of combined PCL and posterolateral corner (PLC) reconstruct

SurgeryMedicine
14
Article|35 citations·2020
Craniofacial and dental injuries associated with stand‐up electric scooters
Minsik Kim, Soyeon Lee, Dong Ryul Ko, Dae‐Hoon Kim, Jong‐Ki Huh, Jae‐Young Kim
SJR Q1Dental TraumatologyOA

BACKGROUND/AIM: With the recent increased share of stand-up electric scooters (e-scooters), it is common to see people riding e-scooters on the roads in Korea. The aim of this study was to investigate traumatic injuries to the craniofacial region related to e-scooter accidents and to determine the role of dentists (especially oral and maxillofacial surgeons) in the evaluation of patients with trauma at the emergency department due to an e-scooter accident. MATERIALS AND METHODS: This retrospecti

TransportationSocial Sciences
15
Article|35 citations·2007
Evidence for expansion-based temporal BMP4/NOGGIN interactions in specifying periodontium morphogenesis
Jae‐Young Kim, Sung Won Cho, Heui-Jung Hwang, Min-Jung Lee, Jong‐Min Lee, Jinglei Cai, Seong‐Ho Choi, Chong‐Kwan Kim, Han‐Sung Jung
SJR Q1Cell and Tissue ResearchOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology

Research Areas

Molecular BiologySurgeryOncologyOral SurgeryNeurologyPulmonary and Respiratory Medicine

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