Jeongho Shin
Korea University · Medicine
About the Lab
Professor Jeongho Shin's research lab focuses on reproductive health and gynecological disorders, with a strong emphasis on pelvic floor disorders, endometriosis, adenomyosis, and their associations with metabolic and socioeconomic factors. The lab utilizes large-scale national health insurance claims data to investigate disease prevalence, treatment patterns, and risk factors, particularly in women across different life stages. Key research directions include the pathophysiological mechanisms of uterine disorders, the role of molecular signaling pathways such as β-catenin and TGF-β in adenomyosis, and the impact of BMI and adolescent pregnancy on long-term gynecological and metabolic outcomes. The lab integrates clinical epidemiology with molecular and transcriptomic approaches to uncover novel insights into disease progression and prevention.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15The study aim was to evaluate the prevalence of pelvic organ prolapse using claim data of South Korea and to evaluate treatment patterns. The Korea National Health Insurance Corporation pay medical costs for most diseases. This study used Health Insurance Review & Assessment Service-National Inpatient Sample (HIRA-NIS) 2009-2015. Pelvic organ prolapse was defined by diagnostic code (N81.x). Of the approximately 4.5 million women included in HIRA-NIS 2009-2015, 10,305 women were selected as havin
OBJECTIVE: To investigate the relationship between endometriosis severity and body mass index (BMI). METHODS: Of 481 women seen for endometriosis at a university hospital in Korea, 153 had stage I, 113 had stage II, 110 had stage III, and 105 had stage IV disease. The patients' BMIs were categorized according to World Health Organization criteria for Asian-Pacific populations. RESULTS: Women with early or mild endometriosis (stages I or II) had a significantly higher BMI than those with advanced
Increased ferritin levels may be a determinant for metabolic syndrome in postmenopausal women but not in premenopausal women.
Adolescent pregnancy may be a predictor of osteoporosis in postmenopausal women.
Adenomyosis is defined as the presence of ectopic nests of endometrial glands and stroma within the myometrium. Adenomyosis is a common cause of dysmenorrhea, menorrhagia, and chronic pelvic pain but is often underdiagnosed. Despite its prevalence and severity of symptoms, its pathogenesis and etiology are poorly understood. Our previous study showed that aberrant activation of β-catenin results in adenomyosis through epithelial-mesenchymal transition. Using transcriptomic and ChIP-seq analysis,
OBJECTIVE: To estimate the ectopic pregnancy rate in the Republic of Korea and to identify whether socioeconomic factors contribute to the incidence of ectopic pregnancy. METHODS: Korean National Health Insurance data from January to December 2009 were analyzed to calculate the rate of ectopic pregnancy. RESULTS: Among the patient sample (n=599186), 59261 had diagnosis codes for ectopic pregnancies, abortions, or deliveries, and 1102 ectopic pregnancies were identified. The frequency of ectopic
PROBLEM: The aim of this study was to investigate the concentration of resistin and adiponectin in the peritoneal fluid (PF) of patients with endometriosis. METHOD OF STUDY: PF sampling was obtained from women with (n = 48) and without endometriosis (n = 36), and the anthropometric indices of the patients were measured. Resistin and adiponectin concentrations in the PF were determined using the enzyme-linked immunosorbent assay. RESULTS: The mean concentration of PF resistin was significantly hi
Endometriosis is a chronic inflammatory condition in women, and obesity leads to an inflammatory condition that is directly involved in the etiology of endometriosis. However, observational studies have shown an inverse correlation between endometriosis and a low body mass index (BMI). Obesity does not protect against endometriosis, and on the contrary, an increased BMI may lead to more severe forms of the disease. To determine the effect of obesity on endometriosis, diet-induced and genetically
OBJECTIVE: To estimate the incidence of Bartholin duct cysts and abscesses in the Republic of Korea during 2009. METHODS: A national patient sample (n=599 186) was obtained from Korean Health Insurance Review and Assessment Service data and analyzed to estimate the incidence of Bartholin duct cysts and abscesses among Korean women in 2009. RESULTS: There were 587 Bartholin duct cysts and 757 Bartholin duct abscesses during 2009. The total incidence of Bartholin duct cysts and abscesses was 0.55
This review aimed to summarize the complications and surgical outcomes of robot-assisted sacrocolpopexy. Nineteen original articles on 1,440 robotic sacrocolpopexies were reviewed, and three systematic reviews and meta-analyses were summarized in terms of intraoperative, perioperative, postoperative, and/or surgical outcomes. Robotic sacrocolpopexy has demonstrated low overall complication rates and favorable surgical outcomes. Nevertheless, long-term follow-up outcomes regarding objective and/o
AIM: To investigate the body fat distribution in Korean women with polycystic ovary syndrome (PCOS) and the association of those distribution with metabolic parameters and hormone profiles. METHODS: A total 90 patients with PCOS and 97 women without PCOS (control group) were included in this study. Total body fat, abdominal visceral fat, and subcutaneous fat were determined on abdominal fat computed tomography. Lipid profiles and sex-hormone binding globulin (SHBG), testosterone, free androgen i
Research Areas
Dive deeper into Jeongho Shin's research on Nubint
Open this lab's papers in the app to read with AI, summarize, and cite in your writing.