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Jiyoung Geum

Ewha Womans University · Medicine

About the Lab

Professor Jiyoung Geum's research lab focuses on advancing the management and outcomes of pancreatic ductal adenocarcinoma (PDAC), with a strong emphasis on nutritional support, early detection in high-risk populations, and optimizing chemotherapy strategies. The lab investigates the role of mobile health interventions like the Noom app in improving patient nutrition during chemotherapy, explores the predictive factors for novel chemotherapy regimens such as liposomal irinotecan plus 5-FU/LV, and examines the clinical implications of new-onset diabetes as a potential early marker for PDAC. Additionally, the lab contributes to clinical guidelines aimed at minimizing radiation exposure in fluoroscopy-guided interventional procedures.

pancreatic ductal adenocarcinomachemotherapy optimizationnutritional supportearly detectionradiation safety

Research Overview

Papers
17
Total Citations
88
Papers (5y)
13
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2021
2022
2024
2025
2026
Citations per year (5y)
74total
20212022202420252026

Selected Papers

15
1
Article|40 citations·2021
Usefulness of Smartphone Apps for Improving Nutritional Status of Pancreatic Cancer Patients: Randomized Controlled Trial
Jiyoung Keum, Moon Jae Chung, Young‐In Kim, Hyunyoung Ko, Min Je Sung, Jung Hyun Jo, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Si Young Song, Hee Seung Lee
SJR Q1JMIR mhealth and uhealthOA

Background Approximately 80% of pancreatic ductal adenocarcinoma (PDAC) patients suffer from anorexia, weight loss, and asthenia. Most PDAC patients receive chemotherapy, which often worsens their nutritional status owing to the adverse effects of chemotherapy. Malnutrition of PDAC patients is known to be associated with poor prognosis; therefore, nutritional management during chemotherapy is a key factor influencing the outcome of the treatment. Mobile apps have the potential to provide readily

PhysiologyMedicine
2
Article|24 citations·2022
Difference of Risk of Pancreatic Cancer in New-Onset Diabetes and Long-standing Diabetes: A Population-based Cohort Study
Hee Seung Lee, Wonjeong Chae, Min Je Sung, Jiyoung Keum, Jung Hyun Jo, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Eun‐Cheol Park, Chung Mo Nam, Sung‐In Jang
SJR Q1The Journal of Clinical Endocrinology & MetabolismOA

CONTEXT: Considering the absence of methods to find pancreatic cancer early, surveillance of high-risk groups is needed for early diagnosis. OBJECTIVE: The study aimed to investigate the effect in the incidence of pancreatic cancer and the differences between new-onset diabetes mellitus (NODM) and long-standing DM (LSDM) since NODM group is a representative high-risk group. METHODS: The Korean National Health Insurance Service-National Sample Cohort between 2002 and 2013 data were used. Regardin

OncologyMedicine
3
Article|14 citations·2020
Single-center risk factor analysis for FOLFIRINOX associated febrile neutropenia in patients with pancreatic cancer
Jiyoung Keum, Hee Seung Lee, Huapyong Kang, Jung Hyun Jo, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Seungmin Bang
SJR Q1Cancer Chemotherapy and PharmacologyOA
OncologyMedicine
4
Article|9 citations·2021
Response to Neoadjuvant Therapy and Prognosis in Patients with Resectable Pancreatic Cancer: A Propensity Score Matching Analysis
Min Sung Yoon, Hee Seung Lee, Chang Moo Kang, Woo Jung Lee, Jiyoung Keum, Min Je Sung, Seung‐seob Kim, Mi‐Suk Park, Jung Hyun Jo, Moon Jae Chung, Jeong Youp Park, Seung Woo Park
SJR Q1Gut and LiverOA

We observed significantly better surgical outcomes and progression-free survival with the addition of neoadjuvant therapy to the management of resectable PDAC. However, despite PSM, there was still selection bias due to the use of different regimens between the groups receiving surgery first and neoadjuvant therapy. Large homogeneous samples are needed in the future prospective studies.

OncologyMedicine
5
Article|1 citations·2024
Survival predictors in patients with pancreatic cancer on liposomal irinotecan plus fluorouracil/leucovorin: a multicenter observational study
Jiyoung Keum, Hee Seung Lee, Chan Su Park, Jeehoon Kim, Wonjoon Jang, Kyung In Shin, Huapyong Kang, Sang Hoon Lee, Jung Hyun Jo, Sung Ill Jang, Moon Jae Chung, Jeong Youp Park
SJR Q1Therapeutic Advances in Medical OncologyOA

Background: Approximately half of the patients with advanced pancreatic ductal adenocarcinoma (PDAC) receive subsequent lines of chemotherapy. Recently, the liposomal irinotecan (nal-IRI) plus 5-fluorouracil/leucovorin (5-FU/LV) regimen is recommended as subsequent lines of chemotherapy. However, little is known about the predictive factors for the nal-IRI + 5-FU/LV regimen, especially in patients with previous irinotecan (IRI) exposure. Objectives: We investigated the predictive factors associa

OncologyMedicine
6
Article|0 citations·2020
Single center risk factor analysis for febrile neutropenia in pancreatic cancer patients receiving FOLFIRINOX
Jiyoung Keum, H. Lee, Jung Hyun Jo, Moon Jae Chung, Jeong Youp Park, Sejung Park, Si Young Song, Seungmin Bang
SJR Q1Pancreatology
OncologyMedicine
7
Article|0 citations·2026
Su1855 PEGYLATED GRANULOCYTE COLONY-STIMULATING FACTOR PRIMARY PROPHYLAXIS IN PANCREATIC CANCER PATIENTS RECEIVING FOLFIRINOX: A MULTICENTER PROSPECTIVE COHORT STUDY
Jiyoung Keum, Huapyong Kang, Hee Seung Lee, Sung Ill Jang
SJR Q1Gastrointestinal Endoscopy
EpidemiologyMedicine
8
Article|0 citations·2024
344P Survival predictors in pancreatic cancer patients on liposomal irinotecan plus fluorouracil/leucovorin: A multicenter observational study
Jiyoung Keum, Hyung Soon Lee, C.S. Park, Ji Eun Kim, Won Il Jang, Kyong‐Oh Shin, Hee‐Ju Kang, S.H. Lee, Jung Hwan Jo, Si Hwan Jang, Myung Jin Chung, J.Y. Park
SJR Q1Annals of OncologyOA
OncologyMedicine
9
Article|0 citations·2022
Impact of UGT1A1 Polymorphisms on Febrile Neutropenia in Pancreatic Cancer Patients Receiving FOLFIRINOX: A Single-Center Cohort Study
Jiyoung Keum, Hee Seung Lee, Jung Hyun Jo, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Seungmin Bang
SJR Q1CancersOA

FOLFIRINOX (oxaliplatin, leucovorin, irinotecan, and 5-fluorouracil) is a first-line chemotherapy for metastatic pancreatic cancer (PC). Chemotherapy-induced neutropenia is one of the most serious adverse events associated with advanced PC. Although UGT1A1 polymorphisms are associated with the metabolism of irinotecan, their role as surrogate markers for FOLFIRINOX-induced neutropenia has not been confirmed. We investigated risk factors for FN—in particular, UGT1A1 polymorphisms—in PC patients r

OncologyMedicine
10
Preprint|0 citations·2020
Usefulness of Smartphone Apps for Improving Nutritional Status of Pancreatic Cancer Patients: Randomized Controlled Trial (Preprint)
Jiyoung Keum, Moon Jae Chung, Young‐In Kim, Hyunyoung Ko, Min Je Sung, Jung Hyun Jo, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Si Young Song, Hee Seung Lee

<sec> <title>BACKGROUND</title> Approximately 80% of pancreatic ductal adenocarcinoma (PDAC) patients suffer from anorexia, weight loss, and asthenia. Most PDAC patients receive chemotherapy, which often worsens their nutritional status owing to the adverse effects of chemotherapy. Malnutrition of PDAC patients is known to be associated with poor prognosis; therefore, nutritional management during chemotherapy is a key factor influencing the outcome of the treatment. Mobile apps have the potenti

PhysiologyMedicine
11
Article|0 citations·2019
Sa1363 – Predictive Factors for the Development of Febrile Neutropenia in Pancreatic Cancer Patients Receiving Folfirinox
Jiyoung Keum, Hee Seung Lee, Jung Hyun Jo, Huapyong Kang, Moon Jae Chung, Jeong Youp Park, Seungmin Bang, Seung Woo Park, Si Young Song
SJR Q1GastroenterologyOA
OncologyMedicine
12
Article|0 citations·2026
Su1855 PEGYLATED GRANULOCYTE COLONY-STIMULATING FACTOR PRIMARY PROPHYLAXIS IN PANCREATIC CANCER PATIENTS RECEIVING FOLFIRINOX: A MULTICENTER PROSPECTIVE COHORT STUDY
Jiyoung Keum, Huapyong Kang, Hee Seung Lee, Sung Ill Jang
SJR Q1Gastroenterology
EpidemiologyMedicine
13
Article|0 citations·2025
341P Angiotensin system inhibitors use and its impact on survival in cholangiocarcinoma patients
Jiyoung Keum
SJR Q1Annals of OncologyOA
OncologyMedicine
14
Article|0 citations·2025
Targeted Therapy for Pancreatic Cancer: Focus on KRAS
Jiyoung Keum, Sang Hoon Lee
Journal of Digestive Cancer ResearchOA

5 10% , [1]. (pancreatic ductal adenocarcinoma, PDAC) 90% , [2]. 10

OncologyMedicine
15
Article|0 citations·2024
Guideline for Minimizing Radiation Exposure of Interventionalists during Fluoroscopy-Guided Interventional Procedures
Il Sang Shin, Yun Nah Lee, Jun Kyu Lee, Joo Seong Kim, Sung Bum Kim, Jiyoung Keum, Chang Hoon Oh, Kang Won Lee, Joo Won Chung, Lyo Min Kwon, Nam Hee Kim, Sang Soo Lee
The Korean Journal of Pancreas and Biliary TractOA

As fluoroscopy-guided interventional procedures gain popularity, the associated health threats from radiation exposure to interventionalists during these procedures are increasing. Therefore, an understanding of the potential risks of radiation and careful consideration on minimizing exposure to radiation during the procedures are of paramount importance. The Korean Pancreatobiliary Association has developed a clinical practice guideline to minimize radiation exposure during fluoroscopy-guided i

Radiology, Nuclear Medicine and ImagingMedicine

Research Areas

OncologyPhysiologyEpidemiologyRadiology, Nuclear Medicine and Imaging

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