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Jong Hee Lee

Sungkyunkwan University · Medicine

About the Lab

Professor Jong Hee Lee's research lab specializes in dermatological and aesthetic medicine, focusing on innovative treatments for skin conditions such as melasma, photorejuvenation, and facial rejuvenation. The lab investigates advanced energy-based therapies, including intense pulsed light (IPL), fractional lasers, and botulinum toxin formulations, with an emphasis on safety and efficacy in Asian patients. Additionally, the lab explores nanomaterial synthesis for biomedical applications, particularly gold nanoparticles with tailored morphologies for potential use in diagnostics and therapeutics.

photodynamic therapyaesthetic dermatologyintense pulsed lightnanoparticle synthesisskin rejuvenation

Research Overview

Papers
259
Total Citations
2,792
Papers (5y)
69
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
69total
2022
2023
2024
2025
2026
Citations per year (5y)
338total
20222023202420252026

Selected Papers

15
1
Article|116 citations·2022
Integrated Analysis of Single-Cell and Spatial Transcriptomics in Keloids: Highlights on Fibrovascular Interactions in Keloid Pathogenesis
Joonho Shim, Se Jin Oh, Eunhye Yeo, Ji‐Hye Park, Jai Hee Bae, Seok‐Hyung Kim, Dong‐Youn Lee, Jong Hee Lee
SJR Q1Journal of Investigative Dermatology
DermatologyMedicine
2
Article|105 citations·2011
Role of oral tranexamic acid in melasma patients treated with IPL and low fluence QS Nd:YAG laser
Hyun Hee Cho, Mira Choi, Soyun Cho, Jong Hee Lee
SJR Q1Journal of Dermatological Treatment

Oral TNA may improve clinical efficacy in light- or laser-based melasma treatment especially during the period of relative high sun exposure without serious adverse effects.

DermatologyMedicine
3
Article|66 citations·2017
Laser-assisted topical corticosteroid delivery for the treatment of keloids
Ji‐Hye Park, Ji Young Chun, Jong Hee Lee
SJR Q2Lasers in Medical Science
DermatologyMedicine
4
Article|57 citations·2013
Efficacy and safety of incobotulinum toxin A in periocular rhytides and masseteric hypertrophy: side-by-side comparison with onabotulinum toxin A
Jae Hyung Lee, Jae Hyung Lee, Ji Ho Park, Soo Keun Lee, Kwang Ho Han, Sang Duck Kim, Chun Yoon, Jae Young Park, Joo Heung Lee, Joo Heung Lee, Jun Yang, Jong Hee Lee
SJR Q1Journal of Dermatological Treatment

BACKGROUND: Incobotulinum is a newly developed botulinum toxin A in which the complexing proteins had been removed. OBJECTIVE: The aim was to compare the efficacy and safety of incobotulinum with onabotulinum in treating periocular rhytides and masseteric hypertrophy. METHODS: A randomized, double-blind, split-face study was planned. Fifty-six patients were treated for periocular rhytides and the other 56 patients were treated for masseteric hypertrophy. Onabotulinum was injected on one side of

NeurologyMedicine
5
Article|50 citations·2007
Morphology-selective synthesis of polyhedral gold nanoparticles: What factors control the size and morphology of gold nanoparticles in a wet-chemical process
Jong Hee Lee, Kai Kamada, Naoya Enomoto, Junichi Hojo
SJR Q1Journal of Colloid and Interface Science
Electronic, Optical and Magnetic MaterialsMaterials Science
6
Article|48 citations·2005
The effects of epigallocatechin-3-gallate on extracellular matrix metabolism
Jong Hee Lee, Jin Ho Chung, Kwang Hyun Cho
SJR Q1Journal of Dermatological Science
DermatologyMedicine
7
Article|43 citations·2008
Polyhedral Gold Nanoplate: High Fraction Synthesis of Two-Dimensional Nanoparticles through Rapid Heating Process
Jong Hee Lee, Kai Kamada, Naoya Enomoto, Junichi Hojo
SJR Q2Crystal Growth & Design

The morphology of gold nanoparticles was controlled with hydrogentetrachloroaurate (HAuCl 4 ) and polyvinylpyrrolidon (PVP) through a polyol process using ethyleneglycol as solvent and reducing agent. The polyol process gave various particle morphologies: trihedron, tetrahedron, hexahedron, and sphere in the size range of 100−1000 nm. The polyhedral nanoplate fraction (PNF) was increased by injection of HAuCl 4 and PVP to preheated ethyleneglycol. The synthesis method, so-called rapid heating pr

Electronic, Optical and Magnetic MaterialsMaterials Science
8
Review|34 citations·2015
Patient Blood Management in Hip Replacement Arthroplasty
Jong Hee Lee, Seung-Beom Han
SJR Q2Hip & PelvisOA

Perioperative blood transfusions are common in total hip arthroplasty because of preoperative anemia and perioperative blood loss. Perioperative anemia and the need for allogeneic blood transfusion are related with increased morbidity. To reduce perioperative allogeneic blood transfusion, keeping the preoperative hemoglobin level above 12.0 g/dL is important in orthopedic patients. By using the anti-fibrinolytic agent or perioperative cell salvage, reduce intraoperative blood loss is very import

BiochemistryMedicine
9
Article|30 citations·2006
Photoepilation Results of Axillary Hair in Dark-Skinned Patients by IPL: A Comparison Between Different Wavelength and Pulse Width
Jong Hee Lee, Chang‐Hun Huh, Ho Joon Yoon, Kwang Hyun Cho, Jin Ho Chung
SJR Q2Dermatologic Surgery

An IPL source removing 45 nm of the emitted spectra and applying a longer pulse width was found to provide a safer and more effective means of photo-epilation in Asian patients.

DermatologyMedicine
10
Article|22 citations·2014
Photodynamic therapy using a new formulation of 5-aminolevulinic acid for wrinkles in Asian skin: A randomized controlled split face study
Hyun‐Tae Shin, Jun Hwan Kim, Joonho Shim, Jong Hee Lee, Jong Hee Lee, Dong Youn Lee, Joo Heung Lee, Joo Heung Lee, Jun Yang
SJR Q1Journal of Dermatological Treatment

BACKGROUND: Photodynamic therapy (PDT) with intense pulsed light (IPL) was proven effective for photorejuvenation. Recently, a new formulation of 0.5% 5-aminolevulinic acid (ALA) liposomal spray has been available. We designed a randomized split face study to evaluate usefulness and safety of IPL-PDT using a liposomal spray for periorbital wrinkles in Asians. METHODS: Patients received three treatments every 3 weeks. The half of the face was treated with IPL-PDT and the other half with long puls

DermatologyMedicine
11
Article|20 citations·2024
Self‐Powered Electrical Bandage Based on Body‐Coupled Energy Harvesting
Minki Kang, Han-Yup Yum, Hyoung Taek Kim, Byung‐Joon Park, Daniel Sanghyun Cho, Young-Hwan Choi, Hye Jin Kim, Youngmin Cho, Young‐Jun Kim, Dong‐Min Lee, Dong‐Gyu Lee, Hyun‐Cheol Song
SJR Q1Advanced MaterialsOA

Abstract Self‐powered electrical bandages (SEBs), integrated with wearable energy harvesters, can provide an effective and autonomous electrical stimulation (ES) solution for rapid and scarless wound healing. A continuously operating, wireless, and applicable‐to‐comprehensive‐wound ES device is essential for the quick restoration of wounds and convenience. This work illustrates a SEB powered by body‐coupled energy harvesting. The SEB continuously treats the wound with 60‐Hz sinusoidal electrical

Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
Article|17 citations·2019
Objective analysis of volume restoration in atrophic acne scars and skin pores: a split study using human stem cell-conditioned media
Chan Seong Park, Ji‐Hye Park, Cho Rok Kim, Jong Hee Lee
SJR Q1Journal of Dermatological Treatment

<b>Background:</b> It is anticipated that the combined treatments of ablative laser and human stem cell-conditioned media produce the synergistic effects.<b>Objectives:</b> To investigated the effects of human stem cell-conditioned media (HSCM) as a post-procedural agent after fractional CO<sub>2</sub> laser procedure in patients with atrophic acne scars and skin pores. <b>Method:</b> Both cheeks of 15 subjects were treated with a fractional CO<sub>2</sub> laser. HSCM was randomly applied to one

DermatologyMedicine
13
Article|17 citations·2007
In vitro phototoxicity test using artificial skin with melanocytes
Jong Hee Lee, Ji Eun Kim, Beom Joon Kim, Kwang Hyun Cho
SJR Q2Photodermatology Photoimmunology & Photomedicine

BACKGROUND: Exposure to ultraviolet radiation (UVR) has been shown to induce cutaneous biological changes and phototoxic reactions. OBJECTIVE: This study was designed to evaluate the usefulness of artificial skin (AS) composed of keratinocytes and melanocytes as an in vitro phototoxicity model for topical agents. MATERIALS AND METHODS: AS was manufactured with three-dimensionally cultured keratinocytes and melanocytes on a de-epidermized dermis (DED). The photobiological responses in AS with and

DermatologyMedicine
14
Article|14 citations·2011
Better clinical results with long term benefits in melasma patients
Se Young Na, Soyun Cho, Jong Hee Lee
SJR Q1Journal of Dermatological Treatment

Combination treatment may provide more rapid clinical resolution in mixed type melasma with possible long term clinical benefits.

DermatologyMedicine
15
Article|13 citations·2022
Magnesium microneedle patches for under‐eye wrinkles
Donghwi Jang, Joonho Shim, Dong Min Shin, Hyungrye Noh, Se Jin Oh, Ji‐Hye Park, Jong Hee Lee
SJR Q1Dermatologic TherapyOA

Microneedling is a common cosmetic procedure for improvement of wrinkles, acne, scars, and other conditions. Various microneedle (MN) patches have been developed as home care therapy for wrinkles and skin texture. Most of them are made of soluble and absorbable needles. To evaluate the efficacy and safety of non-absorbable magnesium (Mg) MN patches on under-eye wrinkles. A total of 20 subjects aged 27-58 years was enrolled in the study. The subjects applied Mg MN patches on the under-eye wrinkle

DermatologyMedicine

Research Areas

DermatologyEpidemiologyOncologyNeurologyGlobal and Planetary ChangeMaterials Chemistry

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