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Jong Soo Han

Seoul National University · Medicine

About the Lab

Professor Jong Soo Han's research lab focuses on population health and preventive medicine, with a strong emphasis on aging, medication safety in older adults, and environmental health risks. The lab investigates the impact of long-term corticosteroid therapy on tuberculosis risk, polypharmacy and potentially inappropriate medication use in the elderly, and the effects of secondhand smoke on heavy metal burden in women. Additionally, the lab explores digital health interventions, such as mobile text-messaging programs, to improve lifestyle outcomes in occupational and chronic disease management settings.

geriatric pharmacologyenvironmental toxicologydigital health interventionstuberculosis riskpolypharmacy in elderly

Research Overview

Papers
69
Total Citations
789
Papers (5y)
17
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
17total
2022
2023
2024
2025
2026
Citations per year (5y)
21total
20222023202420252026

Selected Papers

15
1
Article|129 citations·1998
Mycobacterium tuberculosis infection in a corticosteroid-treated rheumatic disease patient population.
H. A. Kim, Chang Dal Yoo, Han Joo Baek, Eun Bong Lee, Curie Ahn, Jong Soo Han, Su Hwan Kim, Jong Seok Lee, Kang Won Choe, Y W Song
PubMed

OBJECTIVE: To investigate the incidence and risk factors of Mycobacterium tuberculosis infection in longterm corticosteroid treated rheumatic disease patients. METHODS: We assessed retrospectively the incidence of active tuberculosis and its risk factors in 269 rheumatic disease patients treated with moderate to high doses of corticosteroid for an evaluation period representing 1,035 corticosteroid years of therapy. RESULTS: The mean daily dose of steroid was 18.7 mg prednisolone and the mean da

SurgeryMedicine
2
Article|73 citations·2016
Prescription of potentially inappropriate medication in Korean older adults based on 2012 Beers Criteria: a cross-sectional population based study
You‐Seon Nam, Jong Soo Han, Ju Young Kim, Woo Kyung Bae, Kiheon Lee
SJR Q1BMC GeriatricsOA

BACKGROUND: A high number of elderly people with multiple comorbidities are exposed to the risk of polypharmacy and prescription of potentially inappropriate medication (PIM). The purpose of this study was to determine the prevalence and patterns of PIM prescription in Korean older adults according to the 2012 Beers Criteria. METHODS: A retrospective study was conducted using data from the Korean Health Insurance Review and Assessment (KHIRA) database of outpatient prescription claims collected

Geriatrics and GerontologyMedicine
3
Article|60 citations·2018
Prediction of Subclinical Coronary Artery Disease With Breast Arterial Calcification and Low Bone Mass in Asymptomatic Women
Yeonyee E. Yoon, Kyoung Min Kim, Jong Soo Han, Si‐Hyuck Kang, Eun Ju Chun, Soyeon Ahn, Sun Mi Kim, Sang Il Choi, Bo La Yun, Jung‐Won Suh
SJR Q1JACC. Cardiovascular imaging
Radiology, Nuclear Medicine and ImagingMedicine
4
Article|50 citations·2019
Development and Usability of a Life-Logging Behavior Monitoring Application for Obese Patients
Ju Yeon Lee, Ju Young Kim, Seung Ju You, You Soo Kim, Hye Yeon Koo, Jeong‐Hyun Kim, Sohye Kim, Jung Ha Park, Jong Soo Han, Siye Kil, Hyerim Kim, Ye Seul Yang
SJR Q1Journal of Obesity & Metabolic SyndromeOA

The Dr. Youth app shows acceptable technical effectiveness, user efficiency, and user satisfaction. Future study is warranted to establish the app's clinical efficacy.

General Health ProfessionsHealth Professions
5
Article|49 citations·2015
Effectiveness of 6 Months of Tailored Text Message Reminders for Obese Male Participants in a Worksite Weight Loss Program: Randomized Controlled Trial
Ju Young Kim, Ju Young Kim, Sohee Oh, Steven R. Steinhubl, Sohye Kim, Woo Kyung Bae, Jong Soo Han, Jeong-Hyun Kim, Jeong-Hyun Kim, Keehyuck Lee, Mi Jin Kim
SJR Q1JMIR mhealth and uhealthOA

BACKGROUND: Worksite nutrition and physical activity interventions are important to help overweight and obese employees lose weight, but costs and insufficient sustained motivation prevent the majority of these programs from succeeding. Tailored text messaging in aiding weight management has been effective in several studies, but no studies have evaluated the effect of a tailored text message service on weight loss in a worksite health promotion program. OBJECTIVE: We studied the efficacy of a t

General Health ProfessionsHealth Professions
6
Article|45 citations·2015
Architecture Design of Healthcare Software-as-a-Service Platform for Cloud-Based Clinical Decision Support Service
Sungyoung Oh, Jieun Cha, Myungkyu Ji, Hye‐Kyung Kang, Seok Kim, Eunyoung Heo, Jong Soo Han, Hyunggoo Kang, Hoseok Chae, Hee Hwang, Sooyoung Yoo
SJR Q2Healthcare Informatics ResearchOA

We expect that cloud-based HSPs will allow small and mid-sized hospitals, in addition to large-sized hospitals, to adopt information infrastructures and health information technology with low system operation and maintenance costs.

Health Information ManagementHealth Professions
7
Article|38 citations·2015
Association between secondhand smoke exposure and blood lead and cadmium concentration in community dwelling women: the fifth Korea National Health and Nutrition Examination Survey (2010–2012)
Se Young Jung, Suyeon Kim, Kiheon Lee, Kiheon Lee, Ju Young Kim, Woo Kyung Bae, Keehyuck Lee, Keehyuck Lee, Jong Soo Han, Sarah Kim
SJR Q1BMJ OpenOA

OBJECTIVES: To assess the association between secondhand smoke exposure and blood lead and cadmium concentration in women in South Korea. DESIGN: Population-based cross-sectional study. SETTING: South Korea (Korea National Health and Nutrition Examination Survey V). PARTICIPANTS: 1490 non-smoking women who took part in the fifth Korea National Health and Nutrition Examination Survey (2010-2012), in which blood levels of lead and cadmium were measured. PRIMARY OUTCOME MEASURES: The primary outcom

Health, Toxicology and MutagenesisEnvironmental Science
8
Article|34 citations·2019
Development of Comprehensive Personal Health Records Integrating Patient-Generated Health Data Directly From Samsung S-Health and Apple Health Apps: Retrospective Cross-Sectional Observational Study
Se Young Jung, Jeong‐Whun Kim, Hee Hwang, Keehyuck Lee, Rong‐Min Baek, Ho‐Young Lee, Sooyoung Yoo, Wongeun Song, Jong Soo Han
SJR Q1JMIR mhealth and uhealthOA

This is the first study to examine the factors related to integration of lifelog data from Samsung S-Health and Apple Health apps into EMR-tethered PHRs and factors related to the retrieval of medical documents from PHRs. Our findings on the lifelog data integration can be used to design PHRs as a platform to integrate lifelog data in the future.

General Health ProfessionsHealth Professions
9
Article|31 citations·2015
Prevalence of Chronic Obstructive Lung Disease in Korea Using Data from the Fifth Korea National Health and Nutrition Examination Survey
Hwayeon Park, Se Young Jung, Kiheon Lee, Woo Kyung Bae, Keehyuck Lee, Jong Soo Han, Sarah Kim, Seryung Choo, Jin-Mook Jeong, Hyun-Ray Kim, Hyun Jung Ro, Han-Sol Jeong
SJR Q2Korean Journal of Family MedicineOA

The prevalence of COPD in Korea has been increasing every year, and a higher prevalence was associated with male, older age, more amount of smoking, lower educational level and lower BMI.

Pulmonary and Respiratory MedicineMedicine
10
Review|29 citations·2017
Efficacy of Carboxymethylcellulose and Hyaluronate in Dry Eye Disease: A Systematic Review and Meta-Analysis
Jae Kyeong Song, Kiheon Lee, Hwa Yeon Park, Joon Young Hyon, Seung‐Won Oh, Woo Kyung Bae, Jong Soo Han, Se Young Jung, Yoo Jin Um, Ga-Hye Lee, Ji Hye Yang
SJR Q2Korean Journal of Family MedicineOA

The efficacy of CMC appeared to be better than that of HA in treating dry eye disease, although meta-analysis results were not statistically significant. Further research is needed to better elucidate the difference in efficacy between CMC and HA in treating dry eye disease.

Public Health, Environmental and Occupational HealthMedicine
11
Article|28 citations·2016
Development of a Weight Loss Mobile App Linked With an Accelerometer for Use in the Clinic: Usability, Acceptability, and Early Testing of its Impact on the Patient-Doctor Relationship
Seryung Choo, Ju Young Kim, Ju Young Kim, Se Young Jung, Sarah Kim, Jeong Eun Kim, Jeong Eun Kim, Jong Soo Han, Sohye Kim, Jeong Hyun Kim, Jeong Hyun Kim, Jeehye Kim
SJR Q1JMIR mhealth and uhealthOA

BACKGROUND: Although complications of obesity are well acknowledged and managed by clinicians, management of obesity itself is often difficult, which leads to its underdiagnosis and undertreatment in hospital settings. However, tools that could improve the management of obesity, including self-monitoring, engagement with a social network, and open channels of communication between the patient and doctor, are limited in a clinic-based setting. OBJECTIVE: The objective of our study was to evaluate

General Health ProfessionsHealth Professions
12
Article|5 citations·2024
Machine-learning model for predicting depression in second-hand smokers in cross-sectional data using the Korea National Health and Nutrition Examination Survey
Na Hyun Kim, Myeongju Kim, Jong Soo Han, Hyoju Sohn, Bumjo Oh, Ji‐Won Lee, Sumin Ahn
SJR Q2Digital HealthOA

Objective: Depression among non-smokers at risk of second-hand smoke (SHS) exposure has been a neglected public health concern despite their vulnerability. The objective of this study was to develop high-performance machine-learning (ML) models for the prediction of depression in non-smokers and to identify important predictors of depression for second-hand smokers. Methods: = 11,463). The Patient Health Questionnaire was used to diagnose depression with a total score of 10 or higher. The final

PhysiologyMedicine
13
Article|5 citations·2018
The change of signaling pathway on the electrical stimulated contraction in streptozotocin-induced bladder dysfunction of rats
Jong Soo Han, Young Sil Min, Gil Hyung Kim, Sang-hyun Chae, Yoonjin Nam, Jaehwi Lee, Seok‐Yong Lee, Uy Dong Sohn
SJR Q3Korean Journal of Physiology and PharmacologyOA

Bladder dysfunction is a common complication of diabetes mellitus (DM). However, there have been a few studies evaluating bladder smooth muscle contraction in DM in the presence of pharmacological inhibitors. In the present study, we compared the contractility of bladder smooth muscle from normal rats and DM rats. Furthermore, we utilized pharmacological inhibitors to delineate the mechanisms underlying bladder muscle differences between normal and DM rats. DM was established in 14 days after us

UrologyMedicine
14
Article|4 citations·2018
The Inhibitory Mechanism on Acetylcholine-Induced Contraction of Bladder Smooth Muscle in the Streptozotocin-Induced Diabetic Rat
Jong Soo Han, Su Jin Kim, Yoonjin Nam, Hak Yeong Lee, Geon Min Kim, Dong Min Kim, Uy Dong Sohn
SJR Q1Biomolecules & TherapeuticsOA

Most diabetic patients experience diabetic mellitus (DM) urinary bladder dysfunction. A number of studies evaluate bladder smooth muscle contraction in DM. In this study, we evaluated the change of bladder smooth muscle contraction between normal rats and DM rats. Furthermore, we used pharmacological inhibitors to determine the differences in the signaling pathways between normal and DM rats. Rats in the DM group received an intraperitoneal injection of 65 mg/kg streptozotocin and measured blood

UrologyMedicine
15
Article|0 citations·2016
550O Molecular mechanism of transformation from adenocarcinoma to small-cell lung cancer after EGFR-TKI
Jong Soo Han, Q. Zhang, B. Wang, Qianjun Zhou, Z. Zhang, Shannon Chuai, J-J. Yang, Yi‐Long Wu
SJR Q1Annals of Oncology
Pulmonary and Respiratory MedicineMedicine

Research Areas

General Health ProfessionsGeriatrics and GerontologyHealth Information ManagementPulmonary and Respiratory MedicinePublic Health, Environmental and Occupational HealthEndocrinology, Diabetes and Metabolism

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