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Joo Whan Kim

Seoul National University · Medicine

About the Lab

Professor Joo Whan Kim's research lab specializes in neurosurgical and neurological research, with a focus on stereotactic radiosurgery for brain metastases, spinal and cranial malformations, and the molecular classification of pediatric brain tumors. The lab investigates innovative surgical techniques—such as arthroscopic scaphoid excision and four-corner arthrodesis—and contributes to seismic monitoring following significant earthquakes in Korea. A key emphasis is on improving clinical outcomes through advanced molecular diagnostics, including NanoString-based subgrouping of medulloblastoma, to guide personalized treatment strategies.

neurosurgerymedulloblastomacraniosynostosisseismic monitoringmolecular subgrouping

Research Overview

Papers
59
Total Citations
231
Papers (5y)
44
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
44total
2022
2023
2024
2025
2026
Citations per year (5y)
80total
20222023202420252026

Selected Papers

15
1
Article|72 citations·2016
Fractionated Stereotactic Gamma Knife Radiosurgery for Large Brain Metastases: A Retrospective, Single Center Study
Joo Whan Kim, Hye Ran Park, Jae Meen Lee, Jin‐Wook Kim, Hyun‐Tai Chung, Dong Gyu Kim, Hee‐Won Jung, Sun Ha Paek
SJR Q1PLoS ONEOA

Our findings suggest that consecutive hypofractionated Gamma Knife SRS could be applied to large metastatic brain tumors with effective tumor control and low toxicity rates.

Pulmonary and Respiratory MedicineMedicine
2
Article|25 citations·2020
Comparative study between open and arthroscopic techniques for scaphoid excision and four-corner arthrodesis
Jae Woo Shim, Joo Whan Kim, Min Jong Park
SJR Q1Journal of Hand Surgery (European Volume)

This study presents our technique of arthroscopic scaphoid excision and four-corner arthrodesis and compares the clinical and radiological outcomes with those achieved with the open method. Twenty-seven patients (14 in arthroscopy group and 13 in open group) were included. Bone union was achieved in 13 of 14 patients in the arthroscopy group and in all 13 patients in the open group. In the open group, severe stiffness (flexion–extension arc was 10°) occurred in one patient after surgery. The mea

SurgeryMedicine
3
Article|21 citations·2016
The 12 September 2016 Gyeongju earthquakes: 2. Temporary seismic network for monitoring aftershocks
김광희, 강태섭, 이준기, 김영희, 박영철, 강수영, 한민희, 김정무, 박제찬, 김민욱, 공창환, 허다빈

The ML 5.8 earthquake in Gyeongju, southeastern Korea, on September 12, 2016 11:32:54 (UTC) was the largest earthquake on the Korean Peninsula since instrumental monitoring began in 1978. It was preceded by an ML 5.1 foreshock and is being followed by numerous aftershocks. Within an hour of the mainshock, the first temporary seismic station to monitor aftershocks was installed at about 1.5 km east of the announced epicenter. The current temporary seismic network consists of 27 stations equipped

4
Article|19 citations·2018
Limited Dorsal Myeloschisis: Reconsideration of its Embryological Origin
Joo Whan Kim, Kyu‐Chang Wang, Sangjoon Chong, Seung-Ki Kim, Ji Yeoun Lee
SJR Q1Neurosurgery

BACKGROUND: Limited dorsal myeloschisis (LDM) is postulated to be a result of incomplete dysjunction in primary neurulation. However, clinical experience of LDM located below the first-second sacral (S1-S2) vertebral level, which is formed from secondary neurulation (S2-coccyx), suggested that LDM may not be entirely explained as an error of primary neurulation. OBJECTIVE: To elucidate the location and characteristics of LDM to investigate the possible relation of its pathoembryogenesis to secon

Public Health, Environmental and Occupational HealthMedicine
5
Article|16 citations·2023
Comparison of the clinical features and treatment outcomes of pilocytic astrocytoma in pediatric and adult patients
Joo Whan Kim, Ji Hoon Phi, Seung‐Ki Kim, Joo Ho Lee, Sung‐Hye Park, Jae‐Kyung Won, Jung Yoon Choi, Hyoung Jin Kang, Chul‐Kee Park
SJR Q2Child s Nervous System
GeneticsMedicine
6
Article|10 citations·2022
Molecular subgrouping of medulloblastoma in pediatric population using the NanoString assay and comparison with immunohistochemistry methods
Joo Whan Kim, Sung‐Hye Park, Seung Ah Choi, Seung‐Ki Kim, Eun Jung Koh, Jae‐Kyung Won, Sun Mo Nam, Ji Hoon Phi
SJR Q2BMC CancerOA

PURPOSE: Molecular subgrouping of medulloblastoma has become important due to its impact on risk group stratification. Immunohistochemistry (IHC) has been widely used but it has innate limitations. The NanoString assay has been proposed as an alternative method. This study aims to present the characteristics of medulloblastoma subgrouped by the NanoString assay and to compare the subgrouping results with the IHC method. METHODS: Pediatric patients with histological diagnosis of medulloblastoma w

GeneticsMedicine
7
Article|10 citations·2024
Neurocognitive outcomes and associated clinical factors 5 years after surgery in children with craniosynostosis
Joo Whan Kim, Kyung Hyun Kim, Ji Hoon Phi, Ji Yeoun Lee, Eun Jung Koh, Byung Jun Kim, Jee Hyeok Chung, Min‐Sup Shin, Seung‐Ki Kim
SJR Q1Journal of Neurosurgery Pediatrics

OBJECTIVE: Craniosynostosis involves early closure of one or more sutures, which is known to limit normal cranium growth and interfere with normal brain development. Various surgical methods are used, ranging from minimally invasive strip craniectomy to more extensive whole-vault cranioplasty. This study aimed to evaluate neurocognitive outcomes 5 years after surgical treatment in children with craniosynostosis and to evaluate relevant clinical factors. METHODS: After exclusion of genetically co

GeneticsBiochemistry, Genetics and Molecular Biology
8
Article|7 citations·2016
Brain Edema after Repeat Gamma Knife Radiosurgery for a Large Arteriovenous Malformation: A Case Report
Joo Whan Kim, Hyun‐Tai Chung, Moon Hee Han, Dong Gyu Kim, Sun Ha Paek
SJR Q2Experimental NeurobiologyOA

Brain edema due to venous thrombosis following stereotactic radiosurgery for a cerebral arteriovenous malformation (AVM) has rarely been reported. We report a patient with a large AVM in the eloquent area, and brain edema developed in this area after repeat Gamma knife stereotactic radiosurgery (GKRS). An 18-year-old female presented with a 4-year-history of persistent headache. Magnetic resonance imaging and transfemoral carotid angiogram revealed a high-flow large AVM in the left parieto-occip

NeurologyMedicine
9
Article|6 citations·2024
Proteomic profiling of cerebrospinal fluid reveals TKT as a potential biomarker for medulloblastoma
Joo Whan Kim, Seung Ah Choi, Kisoon Dan, Eun Jung Koh, Saehim Ha, Ji Hoon Phi, Kyung Hyun Kim, Dohyun Han, Seung‐Ki Kim
SJR Q1Scientific ReportsOA

Cerebrospinal fluid (CSF) plays an important role in brain tumors, including medulloblastoma (MBL). Recent advancements in mass spectrometry systems and 'Omics' data analysis methods enable unbiased, high proteome depth research. We conducted proteomic profiling of the total CSF in MBL patients with the purpose of finding a potential diagnostic biomarker for MBL. We quantified 1112 proteins per CSF sample. Feature selection identified four elevated soluble proteins (SPTBN1, HSP90AA1, TKT, and NM

GeneticsMedicine
10
Article|5 citations·2022
Clinical Outcome of Optic Pathway and Hypothalamic Gliomas: A 20-Year Single-Institution Retrospective Study
Joo Whan Kim, Ji Hoon Phi, Ji Yeoun Lee, Eun Jung Koh, Kyung Hyun Kim, Hyoung Jin Kang, Jung Yoon Choi, Sung‐Hye Park, Kyu‐Chang Wang, Seung‐Ki Kim
SJR Q2World Neurosurgery
GeneticsMedicine
11
Review|4 citations·2023
Technical evolution of pediatric neurosurgery: moyamoya disease
Joo Whan Kim, Toshiaki Hayashi, Seung‐Ki Kim, Reizo Shirane
SJR Q2Child s Nervous System
RheumatologyMedicine
12
Article|4 citations·2022
Myelomeningocele as an anomaly of secondary neurulation
Ji Yeoun Lee, Joo Whan Kim, Youngbo Shim, Saet Pyoul Kim, Kyung Hyun Kim, Jeyul Yang, Seung‐Ki Kim, Kyu‐Chang Wang
SJR Q2Child s Nervous SystemOA
Public Health, Environmental and Occupational HealthMedicine
13
Article|3 citations·2022
Diverse Patterns and Clinical Significance of 11C-Methionine PET in Dysembryoplastic Neuroepithelial Tumors
Joo Whan Kim, Yeon-koo Kang, Jin Chul Paeng, Seung‐Ki Kim, Byung Chan Lim, Ki Joong Kim, Ji Hoon Phi
SJR Q2Clinical Nuclear Medicine

PURPOSE: Dysembryoplastic neuroepithelial tumors (DNETs) are slow-growing epilepsy-associated tumors. Low or normal 11C-methionine (MET) PET uptake helps to differentiate DNETs from other low-grade gliomas. However, diverse MET-PET uptake in DNETs has been observed. The aim of this study is to measure the clinical significance and prognostic value of MET-PET in DNET management. PATIENTS AND METHODS: Retrospective review of 26 DNET patients was done. Clinical characteristics, radiologic findings,

Psychiatry and Mental healthMedicine
14
Article|3 citations·2024
Comparison of the Transcranial Approach and Transsphenoidal Approach Based on the Anatomical Location of Origin in Pediatric Craniopharyngiomas
Hyun Joo Park, Joo Whan Kim, Byung‐Kyu Cho, Kyu‐Chang Wang, Ji Hoon Phi, Sung‐Hye Park, Young Ah Lee, Choong Ho Shin, Yong Hwy Kim, Seung‐Ki Kim, Yong Hwy Kim, Seung‐Ki Kim
SJR Q2World Neurosurgery
Endocrinology, Diabetes and MetabolismMedicine
15
Article|3 citations·2023
Comparison of Bifrontal Craniotomy and Multiple Burr Hole Encephalogaleoperiosteal-Synangiosis for Pediatric Moyamoya Disease: An Experience of 346 Patients
Joo Whan Kim, Ji Hoon Phi, Ji Yeoun Lee, Eun Jung Koh, Kyung Hyun Kim, Hee‐Soo Kim, Seung‐Ki Kim
SJR Q1Neurosurgery

BACKGROUND AND OBJECTIVES: Moyamoya disease (MMD) is a steno-occlusive disease treated with revascularization surgery. Craniotomy and multiple burr hole encephalogaleoperiosteal-synangiosis (EGPS) are used for revascularization of the anterior cerebral artery territory. The aim of this study was to compare the clinical outcome between the 2 surgical methods in pediatric patients with MMD. METHODS: A retrospective review of patients with MMD who underwent bifrontal indirect bypass surgery was per

RheumatologyMedicine

Research Areas

GeneticsRheumatologyPublic Health, Environmental and Occupational HealthNeurologySurgeryCellular and Molecular Neuroscience

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