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Joo Yong Lee

Yonsei University · Medicine

About the Lab

Professor Joo Yong Lee's research lab specializes in urological interventions, with a primary focus on endourological treatments for urinary stones and bladder cancer. The lab investigates novel and minimally invasive surgical techniques—such as percutaneous nephrolithotomy (PCNL), retrograde intrarenal surgery (RIRS), extracorporeal shock wave lithotripsy (SWL), and photodynamic therapy—aiming to optimize outcomes, improve stone-free rates, and reduce recurrence in renal and ureteral stones. A key research direction involves identifying imaging-based predictors, such as stone heterogeneity index (SHI) and Hounsfield unit variability on non-contrast CT, to enhance treatment selection and predict SWL success. The lab also explores advanced endoscopic imaging techniques like white-light cystoscopy (WLC), narrow-band imaging (NBI), and photodynamic therapy using Radachlorin to improve early detection and management of non-muscle-invasive bladder cancer.

endourologystone diseasebladder cancerlithotripsyimage-guided surgery

Research Overview

Papers
273
Total Citations
3,826
Papers (5y)
58
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
58total
2022
2023
2024
2025
2026
Citations per year (5y)
300total
20222023202420252026

Selected Papers

15
1
Review|145 citations·2019
Comparison of stone-free rates following shock wave lithotripsy, percutaneous nephrolithotomy, and retrograde intrarenal surgery for treatment of renal stones: A systematic review and network meta-analysis
Doo Yong Chung, Dong Hyuk Kang, Kang Su Cho, Won Sik Jeong, Hae Do Jung, Jong Kyou Kwon, Seon Heui Lee, Joo Yong Lee
SJR Q1PLoS ONEOA

PCNL showed the highest success and stone-free rate in the surgical treatment of renal stones. In contrast, SWL had the lowest success and stone-free rate.

Pulmonary and Respiratory MedicineMedicine
2
Article|77 citations·2016
Stone heterogeneity index as the standard deviation of Hounsfield units: A novel predictor for shock-wave lithotripsy outcomes in ureter calculi
Joo Yong Lee, Jae Heon Kim, Dong Hyuk Kang, Doo Yong Chung, Dae Hun Lee, Hae Do Jung, Jong Kyou Kwon, Kang Su Cho
SJR Q1Scientific ReportsOA

We investigated whether stone heterogeneity index (SHI), which a proxy of such variations, was defined as the standard deviation of a Hounsfield unit (HU) on non-contrast computed tomography (NCCT), can be a novel predictor for shock-wave lithotripsy (SWL) outcomes in patients with ureteral stones. Medical records were obtained from the consecutive database of 1,519 patients who underwent the first session of SWL for urinary stones between 2005 and 2013. Ultimately, 604 patients with radiopaque

Pulmonary and Respiratory MedicineMedicine
3
Article|77 citations·2013
Efficacy and Safety of Photodynamic Therapy for Recurrent, High Grade Nonmuscle Invasive Bladder Cancer Refractory or Intolerant to Bacille Calmette-Guérin Immunotherapy
Joo Yong Lee, Richilda Red Diaz, Kang Su Cho, Meng Shi Lim, Jae‐Seung Chung, Won Tae Kim, Won Sik Ham, Young Deuk Choi
SJR Q1The Journal of UrologyOA

Photodynamic therapy with Radachlorin is a safe, effective treatment for nonmuscle invasive bladder cancer refractory or intolerant to bacillus Calmette-Guérin therapy in select patients.

SurgeryMedicine
4
Article|74 citations·2015
A network meta-analysis of therapeutic outcomes after new image technology-assisted transurethral resection for non-muscle invasive bladder cancer: 5-aminolaevulinic acid fluorescence vs hexylaminolevulinate fluorescence vs narrow band imaging
Joo Yong Lee, Kang Su Cho, Dong Hyuk Kang, Hae Do Jung, Jong Kyou Kwon, Cheol Kyu Oh, Won Sik Ham, Young Deuk Choi
SJR Q2BMC CancerOA

The recurrence rate of some bladder cancers can be decreased by the implementation of either PDD- and NBI-assisted TUR; in real settings, clinicians should consider replacing WLC as the standard imaging technology to guide TUR.

SurgeryMedicine
5
Review|51 citations·2017
Systematic review and meta-analysis to compare success rates of retrograde intrarenal surgery versus percutaneous nephrolithotomy for renal stones >2 cm
Sung Ku Kang, Kang Su Cho, Dong Hyuk Kang, Hae Do Jung, Jong Kyou Kwon, Joo Yong Lee
SJR Q3MedicineOA

RIRS can be a safe and effective procedure for selected patients with large renal stones. However, in this meta-analysis, the postoperative stone-free rate of PCNL was higher than that of RIRS in patients with >2 cm renal stones.

Pulmonary and Respiratory MedicineMedicine
6
Review|47 citations·2020
Effectiveness of Percutaneous Nephrolithotomy, Retrograde Intrarenal Surgery, and Extracorporeal Shock Wave Lithotripsy for Treatment of Renal Stones: A Systematic Review and Meta-Analysis
Chan Gyoo Kim, Doo Yong Chung, Koon Ho Rha, Joo Yong Lee, Seon Heui Lee
SJR Q2MedicinaOA

Background and objectives: To perform a updated systematic review and meta-analysis comparing effectiveness of percutaneous nephrolithotomy (PCNL), retrograde intrarenal surgery (RIRS), and extracorporeal shock wave lithotripsy (ESWL) for treatment of renal stones (RS). Materials and Methods: A total of 37 studies were included in this systematic review and meta-analysis about effectiveness to treat RS. Endpoints were stone-free rates (SFR), incidence of auxiliary procedure, retreatment, and com

Pulmonary and Respiratory MedicineMedicine
7
Review|47 citations·2016
Comparison of High, Intermediate, and Low Frequency Shock Wave Lithotripsy for Urinary Tract Stone Disease: Systematic Review and Network Meta-Analysis
Dong Hyuk Kang, Kang Su Cho, Won Sik Ham, Hyungmin Lee, Jong Kyou Kwon, Young Deuk Choi, Joo Yong Lee
SJR Q1PLoS ONEOA

Intermediate- and low-frequency SWL have better treatment outcomes than high-frequency SWL when considering both efficacy and complication.

Pulmonary and Respiratory MedicineMedicine
8
Article|45 citations·2013
Lymphocele after extraperitoneal robot‐assisted radical prostatectomy: A propensity score‐matching study
Joo Yong Lee, Richilda Red Diaz, Kang Su Cho, Ho Song Yu, Jae‐Seung Chung, Won Sik Ham, Young Deuk Choi
SJR Q2International Journal of UrologyOA

OBJECTIVES: To investigate the incidence of lymphocele and determine the risk factors for postoperative lymphocele after extraperitoneal robot-assisted radical prostatectomy by using propensity score-matching. METHODS: A total of 483 patients underwent extraperitoneal robot-assisted radical prostatectomy for prostate cancer between January 2009 and August 2011. Of these, 200 patients underwent pelvic lymph node dissection during robot-assisted radical prostatectomy. All patients underwent magnet

SurgeryMedicine
9
Article|43 citations·2012
Low-power UWB LNA with common-gate and current-reuse techniques
Joo Yong Lee, H. K. Park, Hao-Jen Chang, Tae‐Yeoul Yun
SJR Q3IET Microwaves Antennas & Propagation

A common-gate (CG) low-noise amplifier (LNA) that uses the current-reuse technique and is intended to achieve both ultra-wideband and low-power consumption is proposed. The CG amplifier enables wide-band input matching with low transconductance and low frequency-independent noise figure (NF) when employed at the input stage compared with the common-source amplifier. The current-reuse technique is adopted in order to reduce the power dissipation while achieving reasonable power gain. In addition,

Electrical and Electronic EngineeringEngineering
10
Review|42 citations·2017
Intraoperative and postoperative feasibility and safety of total tubeless, tubeless, small-bore tube, and standard percutaneous nephrolithotomy: a systematic review and network meta-analysis of 16 randomized controlled trials
Joo Yong Lee, Seong Uk Jeh, Man Deuk Kim, Dong Hyuk Kang, Jong Kyou Kwon, Won Sik Ham, Young Deuk Choi, Kang Su Cho
SJR Q2BMC UrologyOA

For hemoglobin changes, total tubeless and small-bore PCNLs may be superior to other methods. For hospital stay, total tubeless and tubeless PCNLs with stent may be superior to other procedures.

Pulmonary and Respiratory MedicineMedicine
11
Review|37 citations·2013
Meta-analysis of Transperitoneal Versus Extraperitoneal Robot-Assisted Radical Prostatectomy for Prostate Cancer
Joo Yong Lee, Richilda Red Diaz, Kang Su Cho, Young Deuk Choi
SJR Q2Journal of Laparoendoscopic & Advanced Surgical TechniquesOA

This meta-analysis suggests that perioperative parameters, including OR time and LOS, may be more favorable for EP-RARP than for TP-RARP. However, the oncologic outcome of margin positivity did not demonstrate a significant difference between the EP and TP approaches.

Pulmonary and Respiratory MedicineMedicine
12
Article|35 citations·2015
Optimal Skin-to-Stone Distance Is a Positive Predictor for Successful Outcomes in Upper Ureter Calculi following Extracorporeal Shock Wave Lithotripsy: A Bayesian Model Averaging Approach
Kang Su Cho, Hae Do Jung, Won Sik Ham, Doo Yong Chung, Yong Jin Kang, Won Sik Jang, Jong Kyou Kwon, Young Deuk Choi, Joo Yong Lee
SJR Q1PLoS ONEOA

Our data indicate that a group 2 SSD of approximately 10 cm is a positive predictor for success following ESWL.

Pulmonary and Respiratory MedicineMedicine
13
Review|31 citations·2023
Update on the Effect of the Urinary Microbiome on Urolithiasis
Hae Do Jung, Seok Cho, Joo Yong Lee
SJR Q2DiagnosticsOA

Microbiota are ecological communities of commensal, symbiotic, and pathogenic microorganisms. The microbiome could be involved in kidney stone formation through hyperoxaluria and calcium oxalate supersaturation, biofilm formation and aggregation, and urothelial injury. Bacteria bind to calcium oxalate crystals, which causes pyelonephritis and leads to changes in nephrons to form Randall’s plaque. The urinary tract microbiome, but not the gut microbiome, can be distinguished between cohorts with

Pulmonary and Respiratory MedicineMedicine
14
Article|31 citations·2014
A Competing Risk Analysis of Cancer-Specific Mortality of Initial Treatment with Radical Prostatectomy versus Radiation Therapy in Clinically Localized High-Risk Prostate Cancer
Joo Yong Lee, Kang Su Cho, Jong Kyou Kwon, Seong Uk Jeh, Ho Won Kang, Richilda Red Diaz, Won Sik Ham, Woong Sub Koom, Ki Chang Keum, Young Deuk Choi
SJR Q1Annals of Surgical OncologyOA
Pulmonary and Respiratory MedicineMedicine
15
Article|29 citations·2014
Meta-Analysis of the Relationship between CXCR4 Expression and Metastasis in Prostate Cancer
Joo Yong Lee, Dong Hyuk Kang, Doo Yong Chung, Jong Kyou Kwon, Hyungmin Lee, Nam Hoon Cho, Young Deuk Choi, Sung Joon Hong, Kang Su Cho
SJR Q1The World Journal of Men s HealthOA

Our meta-analysis showed that the higher CXCR4 protein expression in prostate cancer specimens is significantly associated with the presence of metastatic disease. This supports previous experimental data supporting the role played by the SDF-1/CXCR4 axis in metastasis.

Pulmonary and Respiratory MedicineMedicine

Research Areas

Pulmonary and Respiratory MedicineSurgeryUrologyOncologyPsychiatry and Mental healthRheumatology

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