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Jung Chan Lee

Seoul National University · Medicine

About the Lab

Professor Jung Chan Lee's research lab specializes in biomedical engineering and healthcare technology development, focusing on innovative solutions for critical care and oncology applications. The lab investigates advanced drug delivery systems, such as pressurized intraperitoneal aerosol chemotherapy (PIPAC) and extracorporeal circuit drug sequestration, to improve therapeutic efficacy and patient outcomes. It also develops point-of-care diagnostic devices using smartphone-based imaging and colorimetric sensing for rapid, safe, and accurate blood and urine analysis in emergency and intensive care settings. The lab's work bridges engineering innovation with clinical needs, emphasizing real-time monitoring, reduced turnaround time, and enhanced safety in critical care environments.

drug deliverypoint-of-care diagnosticscritical care engineeringoncology therapybiosensing

Research Overview

Papers
165
Total Citations
2,205
Papers (5y)
32
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
32total
2022
2023
2024
2025
2026
Citations per year (5y)
134total
20222023202420252026

Selected Papers

15
1
Article|101 citations·2001
Potential and limitations of alum or zeolite addition to improve the performance of a submerged membrane bioreactor
Jung Chan Lee, J. S. Kim, In Jeong Kang, Myung‐Haing Cho, P. K. Park, Changhee Lee
SJR Q2Water Science & Technology

In this study, alum and natural zeolite were added to a submerged membrane bioreactor (MBR) not only to reduce membrane fouling but also to increase the removal of nitrogen and phosphorus. Alum addition reduced significantly the rising rate of suction pressure and also resulted in stable and better COD removal. Although phosphorus removal was more than 90% by chemical precipitation, nitrification inhibition was observed. With the addition of natural zeolite, membrane permeability was greatly enh

Water Science and TechnologyEnvironmental Science
2
Article|83 citations·2007
Repair of Damaged Mold Surface by Cold-Spray Method
Jung Chan Lee, Hye-In Kang, W.S. Chu, Sung‐Hoon Ahn
SJR Q1CIRP Annals
Aerospace EngineeringEngineering
3
Article|42 citations·2016
Investigation of Key Circuit Constituents Affecting Drug Sequestration During Extracorporeal Membrane Oxygenation Treatment
Jiheum Park, Dong Ah Shin, Saram Lee, Young‐Jae Cho, Sanghoon Jheon, Jung Chan Lee, Hee Chan Kim
SJR Q1ASAIO Journal

We quantified the influence of the elements of the extracorporeal oxygenation (ECMO) circuit on drug sequestration by focusing on the interactions between materials and drugs. Tubing of three different brands (Tygon/Maquet/Terumo) and oxygenators of two different brands (Maquet/Terumo) were used. Drugs included dexmedetomidine, meropenem, and heparin, which were dissolved in deionized water. Tubing was cut into approximately 7 cm sections and allowed drug solutions enclosed inside by clamping bo

Critical Care and Intensive Care MedicineMedicine
4
Article|25 citations·2021
Development of rotational intraperitoneal pressurized aerosol chemotherapy to enhance drug delivery into the peritoneum
Soo Jin Park, Eun Ji Lee, Hee Su Lee, Jun‐Sik Kim, Sunwoo Park, Jiyeon Ham, Jaehee Mun, Haerin Paik, Hyunji Lim, Aeran Seol, Ga Won Yim, Seung‐Hyuk Shim
SJR Q1Drug DeliveryOA

≤ .05) in all regions except for bowels. In RIPAC, the pharmacokinetic properties reflected hemodynamic changes during capnoperitoneum, and there were no related toxicities. Conclusively, RIPAC may have the potential to enhance drug delivery into the peritoneum compared to PIPAC.

SurgeryMedicine
5
Article|25 citations·2016
Real-time tidal volume feedback guides optimal ventilation during simulated CPR
Kyoung Min You, Chiwon Lee, Woon Yong Kwon, Jung Chan Lee, Gil Joon Suh, Kyung Su Kim, Min Ji Park, Sungwan Kim
SJR Q1The American Journal of Emergency Medicine
Emergency MedicineMedicine
6
Article|18 citations·2020
Evaluation of a Novel Prototype for Pressurized Intraperitoneal Aerosol Chemotherapy
Hee Su Lee, Jun‐Sik Kim, Eun Ji Lee, Soo Jin Park, Jaehee Mun, Haerin Paik, Soo Hyun Oh, Sunwoo Park, Soomin Ryu, Whasun Lim, Gwonhwa Song, Hee Seung Kim
SJR Q1CancersOA

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been suggested as an alternative option for treating peritoneal carcinomatosis (PC). Even with its clinical advantages, the current PIPAC system still suffers from limitations regarding drug distribution area and penetration depth. Thus, we evaluated the new PIPAC system using a novel prototype, and compared its performance to the results from previous studies related with the current MIP® indirectly because the system is currently not

SurgeryMedicine
7
Article|17 citations·2016
Smartphone-Based Urine Reagent Strip Test in the Emergency Department
Karam Choi, Ikwan Chang, Jung Chan Lee, Do Kyun Kim, Seungwoo Noh, Heejeong Ahn, Jun Hwi Cho, Young Ho Kwak, Sungwan Kim, Hee Chan Kim
SJR Q1Telemedicine Journal and e-Health

BACKGROUND: Although a smartphone could be used for a urine reagent strip test, few studies have reported on the reliability of the test in a clinical setting. The objective of our study was to access the smartphone-based urine reagent strip test in the clinical emergency department (ED). MATERIALS AND METHODS: We developed a smartphone-based urine reagent strip reader for a rapid and accurate screening of leukocyte esterase (LE) and nitrite (NIT) in urine. The developed reader was evaluated wit

Biomedical EngineeringEngineering
8
Article|16 citations·2012
Mathematical analysis for internal filtration of convection-enhanced high-flux hemodialyzer
Jung Chan Lee, Kyungsoo Lee, Hee Chan Kim
SJR Q1Computer Methods and Programs in Biomedicine
NephrologyMedicine
9
Article|14 citations·2016
Computer-assisted detection of swallowing difficulty
Jung Chan Lee, Han Gil Seo, Woo Hyung Lee, Hee Chan Kim, Tai Ryoon Han, Byung‐Mo Oh
SJR Q1Computer Methods and Programs in Biomedicine
Speech and HearingHealth Professions
10
Article|14 citations·2017
Application of genetic algorithm for hemodialysis schedule optimization
Jin Woo Choi, Hajeong Lee, Jung Chan Lee, Saram Lee, Yon Su Kim, Hyung‐Jin Yoon, Hee Chan Kim
SJR Q1Computer Methods and Programs in Biomedicine
NephrologyMedicine
11
Article|13 citations·2016
A numerical study of the Coriolis effect in centrifugal microfluidics with different channel arrangements
Jiheum Park, Gi-Hun Lee, Joong Yull Park, Jung Chan Lee, Hee Chan Kim, Jung Chan Lee, Hee Chan Kim
SJR Q2Microfluidics and Nanofluidics
Biomedical EngineeringEngineering
12
Article|12 citations·2021
Point-of-care testing of plasma free hemoglobin and hematocrit for mechanical circulatory support
Dong Ah Shin, Jung Chan Lee, Heean Shin, Young‐Jae Cho, Hee Chan Kim
SJR Q1Scientific ReportsOA

Hematological analysis is essential for patients who are supported by a mechanical circulatory support (MCS). The laboratory methods used to analyze blood components are conventional and accurate, but they require a mandatory turn-around-time for laboratory results, and because of toxic substances, can also be hazardous to analysis workers. Here, a simple and rapid point-of-care device is developed for the measurement of plasma free hemoglobin (PFHb) and hematocrit (Hct), based on colorimetry. T

Biomedical EngineeringEngineering
13
Article|10 citations·2024
Development of artificial intelligence-driven biosignal-sensitive cardiopulmonary resuscitation robot
Taegyun Kim, Gil Joon Suh, Kyung Su Kim, Hayoung Kim, Heesu Park, Woon Yong Kwon, Jaeheung Park, Jaehoon Sim, Sung-moon Hur, Jung Chan Lee, Dong Ah Shin, Woo Sang Cho
SJR Q1Resuscitation
Emergency MedicineMedicine
14
Article|10 citations·2013
글쓰기 교육을 위한 과학 텍스트 분석 연구
이정찬
우리말교육현장연구

본 연구는 ‘과학 글쓰기’에 대한 기존의 개념을 비판적으로 점검하고, 아울러 과학 텍스트의 특징을 고찰함으로써 대학교 교양 교육으로서의 ‘과학 글쓰기’에 적합한 교육 내용을 제안하고자 한다. 과학 글쓰기란 ‘과학계에서 사용하는 지배적인 논증 방식을 통해 실험 혹은 연구의 과정을 객관화하고 거기서 얻어낸 자료를 통해 결론을 일반화하는 일련의 논증 텍스트를 산출’하는 것이라 할 수 있다. 이는 개념화를 통한 논리의 구축, 수치화 및 추론을 통한 인과성의 강조, 귀납적 방법론에 기초한 배열 방식, 문법적 은유와 피동형 문장의 사용 등 과학계에서 사용하는 지배적인 논증의 방식과 그 논증 방식에 적합한 언어적 형식으로 특징지을 수 있다. 따라서 과학 글쓰기 교육이란 단순히 텍스트의 형식만을 대상으로 하는 것이 아닌 학습자로 하여금 과학적 논증의 방식에 대한 이해, 그러한 논증의 방식을 적용하거나 활용해서 타당한 결론을 도출하도록 하는 논증 과정에 대한 이해, 이러한 논증의 방식을 효과적으로

15
Article|10 citations·2008
Comparison of a Pulsatile Blood Pump and a Peristaltic Roller Pump During Hemoperfusion Treatment in a Canine Model of Paraquat Poisoning
Jung Chan Lee, Chan Young Park, Seong Wook Choi, Jeong Chul Kim, Ki Moo Lim, Kyuseok Kim, Sung Koo Jung, Young Ho Kwak, Sang Do Shin, Ik Joon Jo, Gil Joon Suh, Byoung Goo Min
SJR Q2Artificial Organs

This study examined the treatment efficacy and the damage to the blood during hemoperfusion for treating paraquat poisoning using two blood pump mechanisms. Paraquat-poisoned animal models were prepared. A conventional hemodialysis machine, AK90, with a peristaltic roller pump and a cardiopulmonary support system, T-PLS, with a pulsatile blood pump were used during the animal experiments. A total of 12 dogs were treated with hemoperfusion using a charcoal column. Six dogs were treated with hemop

SurgeryMedicine

Research Areas

Emergency MedicineBiomedical EngineeringSurgeryNephrologySpeech and HearingEndocrinology, Diabetes and Metabolism

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