Jung Chan Lee
Seoul National University · Medicine
About the Lab
Professor Jung Chan Lee's research lab specializes in biomedical engineering and healthcare technology development, focusing on innovative solutions for critical care and oncology applications. The lab investigates advanced drug delivery systems, such as pressurized intraperitoneal aerosol chemotherapy (PIPAC) and extracorporeal circuit drug sequestration, to improve therapeutic efficacy and patient outcomes. It also develops point-of-care diagnostic devices using smartphone-based imaging and colorimetric sensing for rapid, safe, and accurate blood and urine analysis in emergency and intensive care settings. The lab's work bridges engineering innovation with clinical needs, emphasizing real-time monitoring, reduced turnaround time, and enhanced safety in critical care environments.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15In this study, alum and natural zeolite were added to a submerged membrane bioreactor (MBR) not only to reduce membrane fouling but also to increase the removal of nitrogen and phosphorus. Alum addition reduced significantly the rising rate of suction pressure and also resulted in stable and better COD removal. Although phosphorus removal was more than 90% by chemical precipitation, nitrification inhibition was observed. With the addition of natural zeolite, membrane permeability was greatly enh
We quantified the influence of the elements of the extracorporeal oxygenation (ECMO) circuit on drug sequestration by focusing on the interactions between materials and drugs. Tubing of three different brands (Tygon/Maquet/Terumo) and oxygenators of two different brands (Maquet/Terumo) were used. Drugs included dexmedetomidine, meropenem, and heparin, which were dissolved in deionized water. Tubing was cut into approximately 7 cm sections and allowed drug solutions enclosed inside by clamping bo
≤ .05) in all regions except for bowels. In RIPAC, the pharmacokinetic properties reflected hemodynamic changes during capnoperitoneum, and there were no related toxicities. Conclusively, RIPAC may have the potential to enhance drug delivery into the peritoneum compared to PIPAC.
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has been suggested as an alternative option for treating peritoneal carcinomatosis (PC). Even with its clinical advantages, the current PIPAC system still suffers from limitations regarding drug distribution area and penetration depth. Thus, we evaluated the new PIPAC system using a novel prototype, and compared its performance to the results from previous studies related with the current MIP® indirectly because the system is currently not
BACKGROUND: Although a smartphone could be used for a urine reagent strip test, few studies have reported on the reliability of the test in a clinical setting. The objective of our study was to access the smartphone-based urine reagent strip test in the clinical emergency department (ED). MATERIALS AND METHODS: We developed a smartphone-based urine reagent strip reader for a rapid and accurate screening of leukocyte esterase (LE) and nitrite (NIT) in urine. The developed reader was evaluated wit
Hematological analysis is essential for patients who are supported by a mechanical circulatory support (MCS). The laboratory methods used to analyze blood components are conventional and accurate, but they require a mandatory turn-around-time for laboratory results, and because of toxic substances, can also be hazardous to analysis workers. Here, a simple and rapid point-of-care device is developed for the measurement of plasma free hemoglobin (PFHb) and hematocrit (Hct), based on colorimetry. T
본 연구는 ‘과학 글쓰기’에 대한 기존의 개념을 비판적으로 점검하고, 아울러 과학 텍스트의 특징을 고찰함으로써 대학교 교양 교육으로서의 ‘과학 글쓰기’에 적합한 교육 내용을 제안하고자 한다. 과학 글쓰기란 ‘과학계에서 사용하는 지배적인 논증 방식을 통해 실험 혹은 연구의 과정을 객관화하고 거기서 얻어낸 자료를 통해 결론을 일반화하는 일련의 논증 텍스트를 산출’하는 것이라 할 수 있다. 이는 개념화를 통한 논리의 구축, 수치화 및 추론을 통한 인과성의 강조, 귀납적 방법론에 기초한 배열 방식, 문법적 은유와 피동형 문장의 사용 등 과학계에서 사용하는 지배적인 논증의 방식과 그 논증 방식에 적합한 언어적 형식으로 특징지을 수 있다. 따라서 과학 글쓰기 교육이란 단순히 텍스트의 형식만을 대상으로 하는 것이 아닌 학습자로 하여금 과학적 논증의 방식에 대한 이해, 그러한 논증의 방식을 적용하거나 활용해서 타당한 결론을 도출하도록 하는 논증 과정에 대한 이해, 이러한 논증의 방식을 효과적으로
This study examined the treatment efficacy and the damage to the blood during hemoperfusion for treating paraquat poisoning using two blood pump mechanisms. Paraquat-poisoned animal models were prepared. A conventional hemodialysis machine, AK90, with a peristaltic roller pump and a cardiopulmonary support system, T-PLS, with a pulsatile blood pump were used during the animal experiments. A total of 12 dogs were treated with hemoperfusion using a charcoal column. Six dogs were treated with hemop
Research Areas
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