Junho Choe

Our study aimed to examine the knowledge and attitude of nursing personnel toward depression in general hospitals of Korea. A total of 851 nursing personnel enrolled at four university-affiliated general hospitals completed self-report questionnaires. Chi-square tests were used to compare the knowledge and attitude of registered or assistant nurses toward depression. In addition, binary logistic regression analysis was used to adjust for the following confounders: age-group and workplace. Regist

Purpose: This study investigated the mental health status, self-esteem, social comparison, and narcissism among medical school students. In addition, the mediational effect of social comparison between self-esteem and narcissism was also tested with regard to whether the students compared themselves with others to enhance their own self-esteem. Methods: Data were collected from 427 medical school students at a medical school in Seoul. The questionnaire included the Minnesota Multiphasic Personal

Ethanol and its metabolite acetaldehyde increase transforming growth factor beta1 (TGF-β1) expression in animal studies. TGF-β1 is related with the hepatic stellate cell (the key element of hepatic fibrogenesis) and the radial glia (the key element of neuronal migration). Blood samples were collected from 41 patients with alcohol dependence, TGF-β1 levels measured by ELISA were compared with 41 normal subjects. Plasma TGF-β1 levels in the patients with alcohol dependence (1,653.11 ±532.45 pg/mL)

Objective To analyze both differentially expressed genes and the Bcl-xL protein expression after acute and chronic treatment with fluoxetine in rat C6 glioma cells. Methods C6 glioma cells were cultured for 24 h or 72 h after treatment with 10 μM fluoxetine, and gene expression patterns were observed using microarray and qRT-PCR. Then, cells were cultured for 6 h, 24 h, 72 h or 96 h after treatment with 10 μM fluoxetine, and the expression of Bcl-xL protein was measured using western blot. Resul

This paper aims to introduce, summarize, and emphasize the importance of the ‘Evidence-Based, Pharmacological Treatment Guideline for Depression in Korea, Revised Edition’. Theguideline broadly covers most aspects of the pharmacological treatment of patients inKorea diagnosed with moderate to severe major depression according to the DSM-IV TR. The guideline establishment process involved determining and answering a number of keyquestions, searching and selecting publications, evaluating recommen

Stress and trauma research has traditionally focused on the negative sequela of adversity. Recently, research has begun to focus on positive outcomes, specifically posttraumatic growth (PTG)–“positive change experienced as a result of the struggle with trauma”–which emphasizes the transformative potential of one’s experiences with highly stressful events and circumstances. For evaluation of PTG, resilience is very important. Resilience refers to a person’s ability to successfully adapt to acute

Language disorganization, an objective component of formal thought process abnormality, has been regarded as a core symptomof schizophrenia from an evolutionary psychopathology perspective. However, to the best of our knowledge, the network structureof language disorganization has rarely been examined in patients with schizophrenia. Thus, our preliminary study aimed to evaluatethe network structure using the Clinical Language Disorder Rating Scale (CLANG) in 167 inpatients with schizophrenia. Al

본 연구는 성범죄자들에게 성범죄에 대한 외현적 및 암묵적 태도를 측정하고, 이 태도에 대한 일반성인과의 차이, 그리고 두 태도간의 관계를 알아보고자 하였다. 성범죄자 집단은 소아성범죄 초범자들이며, 일반성인집단은 성범죄자들의 연령을 고려하여 구성하였다. 성범죄자와 일반성인 집단 별로 성범죄에 대한 암묵적 태도를 측정한 결과, 성범죄 IAT(Implicit Association Test)의 경우 비록 유의미하진 않았으나(t(73)=2.19, p=.062) 어느 정도 경향성을 보였으며, 소아기호 IAT에서는 두 집단 간 차이가 유의미하였다(t(73)=2.30, p<.05). 즉, 일반성인 집단과 다르게 성범죄자 집단이 성범죄 및 소아기호에 대한 왜곡된 인식을 지니고 있었으며, 특히 강간을 긍정적으로 받아들일수록 성범죄를 자행하려는 의도나 실제 자행한 경험이 많아지는 경향이 있었다. 이런 결과로 인해 성범죄자들의 성에 대한 왜곡된 인식을 측정하는데 있어 외현적 태도보다 암묵적 태도를 측정

정신적 외상에 대한 정신건강의학적인 접근은 전통적으로외상후 부정적인 후유증에 초점을 두어왔다. 최근 외상후 개인의 긍정적인 변화에 대한 연구들이 많아졌으며, 특히 ‘외상후 성장’의 개념이 관심을 받고 있다. 외상후 성장이란 외상사건과 투쟁한 결과, 개인에게 긍정적인 심리 변화가 일어나는 주관적 경험이라고 정의된다. 본 종설에서는 외상후 성장의 특성을 규정하는 세 가지 설명 모델로 대처 결과 모델, 대처 전략 모델과 통합 모델을 소개하였다. 또한 본 종설에서는 외상후 성장과 관련한 신경내분비, 신경화학, 뇌신경회로등의 신경 생물학적 관점을 고찰하였다.

Objective: Our study aimed to measure inter-rater and test-retest reliability, concurrent and convergent validity, and factor solutions of the Korean version of the Clinical Language Disorder Rating Scale (CLANG). Methods: The Korean version of the CLANG for assessing thought, language, and communication, the Brief Psychiatric Rating Scale, Young Mania Rating Scale, and Calgary Depression Scale for Schizophrenia were used to evaluate language disorder, formal thought disorder, positive and negat

Purpose: The purpose of this study is to investigate relationship between HRV (heart rate variability) and depressive symptoms in general population. This study was designed to examine the correlation of HRV and depressive symptom in general rural population. Methods: In 155 participants lived in the anonymous rural area of Gyeonggi-do, Korea, they participated in health promotion program with short term electrode HRV test and BDI (Beck’s depression inventory) self-report. Two participants were

A Case of Valproate-Induced Hyperammonemic Encephalopathy

Objectives The aim of this study is to establish Korean pharmacological treatment guidelines for the initial choice of antidepressant for treatment of moderate or severe depression. Methods The process for establishment of guidelines involved determination of important key questions, selection of 12 international and domestic clinical practice guidelines for depression,drawing of recommendation drafts, and peer review. Results Selective serotonin reuptake inhibitors (SSRIs), serotonin-norepineph

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