Keon-Seok Lee
Hanyang University · Health Professions
About the Lab
Professor Keon-Seok Lee's research lab specializes in suicide prevention, psychiatric epidemiology, and severe mental illness, with a strong focus on improving clinical assessment tools and understanding suicide risk factors. The lab investigates the validity and reliability of suicide screening instruments such as the Ask Suicide-Screening Questions (ASQ), explores clinical characteristics of suicide attempters—particularly those using high-lethality methods like carbon monoxide poisoning—and examines the challenges in diagnosing and treating severe psychiatric disorders such as treatment-resistant schizophrenia and bipolar disorder. The lab also contributes to policy-relevant research, including revisions in mental health legislation and the development of standardized diagnostic criteria.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
7Background: The Ask Suicide-Screening Questions (ASQ) tool is a simple suicide screening tool developed to screen patient suicide risk (SR). The purpose of this study was to verify the reliability and validity of the ASQ tool in hospitalized patients. Methods: The internal consistency and test-retest reliability of the South Korean version of the ASQ tool were verified in 99 hospitalized patients admitted to a tertiary medical institution in Seoul. To verify the correlations and validity of each
Background: The rate of suicide by carbon monoxide (CO) poisoning is increasing rapidly in Korea. In this study, we aimed to investigate the clinical characteristics of suicide attempters in Korea and to identify risk groups for choosing CO poisoning as a suicide method. Methods: Patients who visited the emergency department after attempting suicide between April 2017 and June 2019 were included in this study. We reviewed the medical records and evaluated the demographic and clinical data of sui
Purpose: Bipolar disorder (BD) is characterized by alternating episodes of mania or hypomania and depression, resulting in substantial psychosocial impairment. Despite its clinical importance, BD is frequently underrecognized or misdiagnosed as major depressive disorder (MDD) or other psychiatric conditions. This review aims to summarize current diagnostic criteria, key clinical differentiating features, and validated assessment tools in order to enhance diagnostic accuracy and facilitate earlie
INTRODUCTION: Primitive neuroectodermal tumor (PNET) is the most common primary malignant childhood brain tumor and is usually seen as an intraparenchymal lesion, typically arising in the cerebellum (as a medulloblastoma). Peripheral PNET (PPNET), a member of the Ewing's sarcoma (ES) family of tumors, is a tumor of putative parasympathetic neural histogenesis, typically developing in the soft tissue and skeletal structures of the trunk and extremities. We report here four cases of atypical prima
Schizophrenia is one of serious mental illnesses and is often described as a heterogeneous disorder. Approximately one-third of schizophrenia cases are treatment-resistant schizophrenia (TRS). The aim of this study was to review the definitions and clinical features of TRS. Though it was found that the criteria for TRS were considerably diverse, the Treatment Response and Resistance in Psychosis (TRRIP) consensus criteria were recently introduced. According to the TRRIP criteria, TRS should be s
The Mental Health Act of 1995 was fully revised on May 29, 2016, and implemented on May 30, 2017, under the name of the Mental Health Promotion and Mental Health Service Support Act (Mental Health Welfare Act). The act newly defined mentally ill people as those with significant limitations in independent daily life and reduced their classification based on severity. Before the revision, patients could be admitted to the hospital if satisfied with the risk of self-injury or harm to others or the
본 연구는 계절성 정동장애의 정신생리학적 병태생리 및 치료에 대해 살펴보았다. 상대적으로 높은 위도에서 겨울형 SAD 유병률의 높은 것으로 보고되고 있고, 같은 지리적 위 치에서도 민족에 따라 다른 유병률이 보고되고 있어 유전 자-환경의 상호작용이 중요할 질환임을 확인할 수 있었다. 또한, 세로토닌 감소, 멜라토닌 수치의 감소가 보고되고 있 으며, 내부 일주기 리듬의 변화가 발병 및 치료에 있어서 중 요한 요인임을 확인하였다. 이를 통하여 수면/각성 주기와 관련된 생물학적 리듬과 내부 일주기리듬을 재설정하기위 해, 광치료, 광치료의 대안인 새벽 시뮬레이션, 음이온 발생 기 및 약물치료 등을 활용할 수 있으며, 향후 이러한 내용들 을 SAD 환자의 치료에 적용할 근거를 확인하였다.
Research Areas
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