Kyun-Hee Lee
Kyung Hee University · Medicine
About the Lab
Professor Kyun-Hee Lee's research lab focuses on allergic rhinitis, particularly the impact of perennial allergic rhinitis on quality of life and the development of effective treatment strategies, including allergen-specific immunotherapy. The lab also investigates the biological effects of dietary components—such as soy-derived isoflavones—on prostate cancer progression through estrogen receptor pathways. Additionally, the lab contributes to otolaryngological research, including endoscopic sinus surgery complications and rare head and neck tumors like angioleiomyoma.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Background and Objectives:The symptom score index (SSI) has not been able to express fuly the states of the perennial allergic rhinitis patients. So, other tools were demed necessary to not only evaluate the degre of severity but also to evalu-ate the eficacy of the newly developed drugs on perenial allergic rhinitis. The aim of this study was to evaluate the impact of perennial allergic rhinitis on the quality of life of patients and to verify the correlation betwen the nasal symptoms and ot-Ma
Soy milk, which is produced from whole soybeans, contains a variety of biologically active components. Isoflavones are a class of soy-derived phytoestrogens with beneficial effects, among which genistein (GEN) has been previously indicated to reduce the risk of prostate cancer. The present study evaluated the effects of soy milk digestion extract (SMD) on the progression of prostate cancer via the estrogen receptor (ER)β in human LNCaP prostate cancer cells. To evaluate the effects of SMD (daize
Purpose: Allergen-specific immunotherapy is the only currently available treatment to modify the natural history of allergic rhinitis (AR). If patients are polysensitized, it is difficult to identify the allergen causing the allergic symptoms. We evaluated the effectiveness of immunotherapy against house dust mites (HDMs) in AR patients polysensitized to both HDMs and seasonal allergens. Methods: Thirty AR patients polysensitized to both HDMs and seasonal allergens (group A) and 30 patients sens
Angiomyoma is a benign myogenic tumor which can be found wherever smoth muscle is present. They are most commonly found in the alimentary tract, female genito-urinary tract, skin and subcutaneous tissues, but are rare in the area of the head and neck due to the scarcity of smoth muscle tissue. Because of their rarity, these tumors are often clinically misdiagnosed and identified only after histological examination. We present a case of angioleiomyoma which was found in the nasal dorsum and was e
본 연구에서는 한국어 초급 교재에 나타난 불규칙 용언의 활용 기술 방식을 살펴보고, 국립국어원에서 구축한 말뭉치를 바탕으로 한국어 초급 학습자의 용언 불규칙 오류 양상을 용언의 불규칙별, 어휘별로 나누고 그 원인을 고찰하였다. 대부분의 대학 기관 교재에서 불규칙 용언 활용은 주제를 중심으로 관련 어휘를 제시하는 방식으로 이루어지는데 이는 초급 학습자의 불규칙 용언 사용 빈도 및 그에 대한 오류와 차이가 나타났다. 교재 구성 시 한국어 학습에 도움이 되는 문법 항목과 어휘를 제시함과 동시에 학습자의 사용 요구와 습득의 어려움도 함께 고려하여야 할 것이다. 급별로 살펴본 불규칙별 오류 양상에서 특히 ㅂ 불규칙과 ㄹ 탈락의 오류 유형이 가장 다양하게 나타났다. 또한 여타의 불규칙 오류가 1급에 비해 2급에서 감소하거나 비슷하게 나타난 것과 달리 르 불규칙과 ㄹ 탈락의 경우 1급에 비해 2급에서 증가하였다. 이는 높은 사용 빈도에도 불구하고 한국어 학습자는 이 규칙을 복잡하게 여길 뿐만 아
Background and Objectives:Endoscopic sinus surgery (ESS) has been used worldwide since the advent of ES by Me-serklinger and Wigand. There have been many reports concerning the results of ESS on the treatment of chronic paranasal sinusitis, but few reports about the intraoperative complications of ESS in Korea. In this paper, we analyzed the intraoperative complications of ESS in Kyung He University Hospital and discussed about early recognition and managements. Materials and Method:We reviewed
Background and Objectives:The incidence of alergic rhinitis and the kinds of offending allergens in our environment are varying as the way of life changes with urbanization and industrialization. Therefore, knowledge of the relationship betwen allergic rhinitis and the ofending allergen is crucial for therapeutic judgment. The purpose of this study was to find out the incidence and distribution of offending allergens and investigate the prevalence of multiple sensitization on patients with alerg
Background and Objectives Although obstructive sleep apnea is common, it has often gone undiagnosed in primary care encounters until now, with no validated screening tool of obstructive sleep apnea (OSA) for Korean patients. The aim of this study was to investigate the usefulness of Berlin questionnaire (Berlin Q) and STOP questionnaire (STOP Q) as a screening test for sleep apnea for the Korean patients. Subjects and Method We administered Berlin Q and STOP Q to 106 patients who received a full
본 논문은 3차원 입체효과를 나타내는 기술 중 가장 널리 쓰이고 있는 스테레오스코픽 영상을 방송 환경에서 활용되어지고 있는 MPEG-2 전송스트림(Transport Stream : TS)을 통해 효율적으로 서비스를 하기 위한 방법을 제안한다. 전통적인 MPEG-2 전송스트림은 오디오, 비디오, 그리고 부가 데이터로 구성된 프로그램들을 각 데이터간의 동기 및 타이밍 기능을 제공하고 다중화함으로써 오디오, 비디오 및 데이터의 실시간 전송을 가능하게 한다. 그러나, 이러한 MPEG-2 전송스트림은 2D 영상을 기준으로 제정된 기술 규격으로 스테레오스코픽 영상을 위한 동기화, 다중화 처리 및 스테레오스코픽 동영상 식별이 어렵기에 스테레오스코픽 영상 서비스로 활용하기에는 어려움이 존재한다. 본 논문에서는 전통적인 MPEG-2 전송스트림의 2D 비디오 서비스와 호환성을 가지며 스테레오스코픽 비디오 서비스를 제공할 수 있도록 스테레오스코픽 비디오의 식별, 다중화 처리 및 동기화 처리를 위한 알고
Endoscopic endonasal approach (EEA) for the skull base surgery has been widely accepted since the advent of image guidance system and new reconstruction method. EEA has the advantage of being non-invasive approach with low morbidity. Among many reconstructive methods nasoseptal flap is the method of choice because of the proximity to the skull base and hypervascularity as a pedicled flap. In this review, the authors introduce the indication, surgical techniques and postoperative complications of
Fibrous dysplasia is a developmental disease of the bone, characterized by the replacement of normal spongiosa and filling of the medullary cavity of affected bones by an abnormal fibrous tissue. Fibrous dysplasia arising in the paranasal sinus is are predominant:the monostotic type, in which only one bone is afected;and the polyostotic type, in which multiple bo-nes are affected. Recently, we experienced a case of monostotic fibrous dysplasia which was confined to the maxillary sinus and approa
Background and Objectives:fluid with sparse fibrous cells, few mucous glands and proliferation of stromal and epithelial cells. There have been many studies done separately about epithelial cels, fibroblasts, and other inflammatory cells in nasal polyps. However, there is no usable study model for the cell-to-cell interaction. Therefore, we tried to make a new model for the study of nasal polyp by coculture of epithelial cells and fibroblasts. Subjects and Method:Nasal polyp was colected during
In recent years, the emphasis on medical care has shifted from symptom scores and objective test results to the patient-centered assesment of effect of disease or response to treatment. So, we compared, before and after endoscopic sinus surgery (ESS), the relationship between 7 nasal symptom scores and quality of life scores measured with RSDI and the SF-36v2TM questionnaires, which have been verified by many articles. Subjects and Method:Subjects were 50 patients diagnosed as chronic sinusitis
Objectives. Alpha1-antitrypsin (AAT) is the main inhibitor of human neutrophil elastase, and plays a role in counteracting the tissue damage caused by elastase in local inflammatory conditions. The study evaluated the involvement of AAT in nasal allergic inflammation. Methods. Forty subjects with mono-sensitization to Dermatophagoides pteronyssinus (Dpt) were enrolled. Twenty allergic rhinitis patients frequently complained of nasal symptoms such as rhinorrhea, stuffiness, sneezing, and showed p
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