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Kyung-Hun Yu

Hanyang University · Medicine

About the Lab

Professor Kyung-Hun Yu's research lab specializes in critical care medicine and emergency therapeutics, with a strong focus on improving outcomes for patients following out-of-hospital cardiac arrest (OHCA). The lab investigates psychiatric and psychological recovery in OHCA survivors, explores genetic predictors of treatment response in depression, and evaluates resuscitation techniques and antivenom therapies in emergency settings. Key research directions include prognostic factors in OHCA, early biomarkers for depression remission, and optimizing emergency interventions through genetic and clinical data integration. The lab combines population-based cohort studies, genetic analyses, and clinical trials to advance precision medicine in critical care.

out-of-hospital cardiac arrestdepression geneticsresuscitation outcomesantivenom therapypsychiatric recovery

Research Overview

Papers
29
Total Citations
154
Papers (5y)
22
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
22total
2022
2023
2024
2025
2026
Citations per year (5y)
85total
20222023202420252026

Selected Papers

15
1
Article|22 citations·2023
Analysis of Anxiety or Depression and Long-term Mortality Among Survivors of Out-of-Hospital Cardiac Arrest
Juncheol Lee, Yongil Cho, Jaehoon Oh, Hyunggoo Kang, Tae Ho Lim, Byuk Sung Ko, Kyung Hun Yoo, Sang Hwan Lee
SJR Q1JAMA Network OpenOA

Importance: The recent American Heart Association guidelines added a sixth link in the chain of survival highlighting recovery and emphasized the importance of psychiatric outcome and recovery for survivors of out-of-hospital cardiac arrest (OHCA). The prevalence of psychiatric disorders among this population was higher than that in the general population. Objective: To examine the prevalence of depression or anxiety and the association of these conditions with long-term mortality among individu

Emergency MedicineMedicine
2
Article|20 citations·2023
The usefulness of lactate/albumin ratio, C-reactive protein/albumin ratio, procalcitonin/albumin ratio, SOFA, and qSOFA in predicting the prognosis of patients with sepsis who presented to EDs
Kyung Hun Yoo, Sung‐Hyuk Choi, Gil Joon Suh, Sung Phil Chung, Han Sung Choi, Yoo Seok Park, You Hwan Jo, Tae Gun Shin, Tae Ho Lim, Won Young Kim, Juncheol Lee
SJR Q1The American Journal of Emergency Medicine
EpidemiologyMedicine
3
Article|18 citations·2018
Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects
Heewon Seo, Eun Jin Kwon, Young‐Ah You, Yoomi Park, Byung Joo Min, Kyung Hun Yoo, Han Sung Hwang, Ju Han Kim, Young Ju Kim
SJR Q3BMC Medical GenomicsOA

Ritodrine-induced cardiac and pulmonary side effects may be associated with deleterious genetic variants in ciliary and pharmacokinetic genes.

Pulmonary and Respiratory MedicineMedicine
4
Review|16 citations·2019
Comparison of two-thumb encircling and two-finger technique during infant cardiopulmonary resuscitation with single rescuer in simulation studies
Ji Eun Lee, Juncheol Lee, Jaehoon Oh, Chan Hyuk Park, Hyunggoo Kang, Tae Ho Lim, Kyung Hun Yoo
SJR Q3MedicineOA

BACKGROUND: The recommended chest compression technique for a single rescuer performing infant cardiopulmonary resuscitation is the two-finger technique. For 2 rescuers, a two-thumb-encircling hands technique is recommended. Several recent studies have reported that the two-thumb-encircling hands technique is more effective for high-quality chest compression than the two-finger technique for a single rescuer performing infant cardiopulmonary resuscitation. We undertook a systematic review and me

Emergency MedicineMedicine
5
Article|16 citations·2020
Genetic Markers for Later Remission in Response to Early Improvement of Antidepressants
Hee‐Ju Kang, Ki‐Tae Kim, Kyung Hun Yoo, Yoomi Park, Ju‐Wan Kim, Ju‐Wan Kim, Sung‐Wan Kim, Il‐Seon Shin, Ju Han Kim, Ju Han Kim, Jae-Min Kim, Jae-Min Kim
SJR Q1International Journal of Molecular SciencesOA

Planning subsequent treatment strategies based on early responses rather than waiting for delayed antidepressant action can be helpful. We identified genetic markers for later non-remission in patients exhibiting poor early improvement using whole-exome sequencing data of depressive patients treated in a naturalistic manner. Among 1000 patients, early improvement at 2 weeks (reduction in Hamilton Depression Rating Scale [HAM-D] score ≥ 20%) and remission at 12 weeks (HAM-D score ≤ 7) were evalua

PharmacologyMedicine
6
Article|16 citations·2019
Effectiveness of repeated antivenom therapy for snakebite-related systemic complications
Kyung Hoon Park, Hyungoo Shin, Hyunggoo Kang, Changsun Kim, Hyuk Joong Choi, Kyung Hun Yoo, Jaehoon Oh, Tae Ho Lim
SJR Q3Journal of International Medical ResearchOA

Objective This study aimed to determine the effect of repeated antivenom therapy compared with that of single antivenom therapy for treating snakebite-related systemic complications. Methods A retrospective medical record review from January 2008 to September 2016 was performed. Patients with snakebite injury who visited the Emergency Department in one tertiary center of Korea were included. The primary outcome was the survival rate. The secondary outcome was the effect of repeated antivenom the

GeneticsBiochemistry, Genetics and Molecular Biology
7
Article|10 citations·2023
Association of Socioeconomic Status With Long-Term Outcome in Survivors After Out-of-Hospital Cardiac Arrest: Nationwide Population-Based Longitudinal Study
Kyung Hun Yoo, Yongil Cho, Jaehoon Oh, Juncheol Lee, Byuk Sung Ko, Hyunggoo Kang, Tae Ho Lim, Sang Hwan Lee
SJR Q1JMIR Public Health and SurveillanceOA

BACKGROUND: Out-of-hospital cardiac arrest (OHCA) is a major public health problem and a leading cause of death worldwide. Previous studies have focused on improving the survival of people who have had OHCA by analyzing short-term survival outcomes, such as the return of spontaneous circulation, 30-day survival, and survival to discharge. Research has been conducted on prehospital prognostic factors to improve the survival of patients with OHCA, among which the association between socioeconomic

Emergency MedicineMedicine
8
Article|7 citations·2023
Predicting acute brain lesions on magnetic resonance imaging in acute carbon monoxide poisoning: a multicenter prospective observational study
Kyung Hun Yoo, Hyunggoo Kang, Jaehoon Oh, Tae Ho Lim, Yongil Cho, Juncheol Lee, Sang Hwan Lee, Seungkyo Jung, Won Young Kim, Chang Hwan Sohn, Byuk Sung Ko
SJR Q1Scientific ReportsOA

An acute brain lesion (ABL) identified by brain magnetic resonance imaging (MRI) after acute carbon monoxide (CO) poisoning is a strong prognostic factor for the development of delayed neuropsychiatric syndrome (DNS). This study aimed to identify predictors of ABLs on MRI in patients with acute CO poisoning. This was a multicenter prospective registry-based observational study conducted at two tertiary hospitals. A total of 1,034 patients were included. Multivariable logistic regression analysis

Molecular BiologyBiochemistry, Genetics and Molecular Biology
9
Article|6 citations·2025
Depression or anxiety and long-term mortality among adult survivors of intensive care unit: a population-based cohort study
Kyung Hun Yoo, Juncheol Lee, Young Taeck Oh, Nayeon Choi, Tae Ho Lim, Hyunggoo Kang, Byuk Sung Ko, Yongil Cho
SJR Q1Critical CareOA

ICU survivors newly diagnosed with depression or anxiety exhibit higher long-term mortality rates compared to those without such diagnoses, including those diagnosed before ICU admission. Particularly, newly diagnosed depression is associated with an elevated mortality rate. These findings underscore the need for psychological interventions to enhance long-term survival among ICU survivors.

Critical Care and Intensive Care MedicineMedicine
10
Article|5 citations·2023
Effectiveness of Initial Troponin I and Brain Natriuretic Peptide Levels as Biomarkers for Predicting Delayed Neuropsychiatric Sequelae in Patients with CO Poisoning: A Retrospective Multicenter Observational Study
Myung Hyun Jung, Juncheol Lee, Jaehoon Oh, Byuk Sung Ko, Tae Ho Lim, Hyunggoo Kang, Yongil Cho, Kyung Hun Yoo, Sang Hwan Lee, Chang Hwan Sohn, Won Young Kim
SJR Q2Journal of Personalized MedicineOA

Background: Delayed neuropsychiatric sequelae (DNS) are a severe complication of carbon monoxide (CO) poisoning, and predicting DNS is difficult. This study aimed to investigate whether cardiac markers can be used as biomarkers to predict DNS occurrence following acute CO poisoning. Methods: This was a retrospective observational study that included patients with acute CO poisoning who visited two emergency medical centers in Korea from January 2008 to December 2020. The primary outcome was whet

Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
Article|4 citations·2023
The prognostic value of the phosphate-to-albumin ratio in patients with OHCA: A multicenter observational study
Kyung Hun Yoo, Juncheol Lee, Jaehoon Oh, Tae Ho Lim, Hyunggoo Kang, Byuk Sung Ko, Yongil Cho
SJR Q1The American Journal of Emergency Medicine
Emergency MedicineMedicine
12
Article|3 citations·2025
Bystander interventions and clinical outcomes among adult out-of-hospital cardiac arrest victims in South Korea over a decade: Sex-based disparities
Kyung Hun Yoo, Jaehoon Oh, Tae Ho Lim, Hyunggoo Kang, Byuk Sung Ko, Yongil Cho, Juncheol Lee
SJR Q1Public Health
Emergency MedicineMedicine
13
Article|3 citations·2018
Comparison of Heart Proportions Compressed by Chest Compressions Between Geriatric and Nongeriatric Patients Using Mathematical Methods and Chest Computed Tomography: A Retrospective Study
Kyung Hun Yoo, Jaehoon Oh, Heekyung Lee, Juncheol Lee, Hyunggoo Kang, Tae Ho Lim, Soon Young Song, Solji Kim
SJR Q2Annals of Geriatric Medicine and ResearchOA

BACKGROUND: Current guidelines recommended that chest compression depths during car-diopulmonary resuscitation (CPR) should be at least one-fifth of the external chest ante-riorposterior (AP) diameter. The chest AP diameter increases because of dorsal kyphosis, senile emphysema, and poor lung compliance associated with aging. This study aimed to compare the proportion of the heart compressed by chest compression (based on the ejection fraction [EF]) in geriatric and nongeriatric patients. METHOD

Emergency MedicineMedicine
14
Article|2 citations·2023
Diagnostic performance of rapid antigen tests for SARS-CoV-2 transmission risk based on cycle threshold values in the emergency department
Sang Hwan Lee, Juncheol Lee, Yongil Cho, Tae Ho Lim, Hyunggoo Kang, Jaehoon Oh, Kyung Hun Yoo, Byuk Sung Ko
SJR Q1The American Journal of Emergency Medicine
Infectious DiseasesMedicine
15
Article|2 citations·2024
Total cholesterol and bilirubin levels are associated with neurologic outcomes in patients with out-of-hospital cardiac arrest
Sang Hwan Lee, Yongil Cho, Jaehoon Oh, Hyunggoo Kang, Tae Ho Lim, Byuk Sung Ko, Kyung Hun Yoo, Juncheol Lee
SJR Q1Internal and Emergency Medicine
Emergency MedicineMedicine

Research Areas

Emergency MedicineMolecular BiologyEpidemiologyInfectious DiseasesPulmonary and Respiratory MedicineGenetics

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