Kyung-Hwa Han
Yonsei University · Medicine
About the Lab
Professor Kyung-Hwa Han's research lab specializes in diagnostic and prognostic radiology, with a strong focus on improving clinical decision-making through advanced medical imaging and artificial intelligence. The lab investigates the integration of radiological findings—particularly from MRI and contrast-enhanced imaging—into predictive models to enhance disease diagnosis and outcome prediction. A key area of innovation involves the development and evaluation of AI-generated radiology reports for accuracy, patient-friendliness, and clinical utility, while rigorously assessing for artificial hallucinations. The lab also emphasizes methodological rigor in radiological research, including inter-reader agreement and survival analysis using Cox regression with attention to real-world data limitations.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Clinical prediction models are developed to calculate estimates of the probability of the presence/occurrence or future course of a particular prognostic or diagnostic outcome from multiple clinical or non-clinical parameters. Radiologic imaging techniques are being developed for accurate detection and early diagnosis of disease, which will eventually affect patient outcomes. Hence, results obtained by radiological means, especially diagnostic imaging, are frequently incorporated into a clinical
In radiological research, survival analysis has been increasingly used to evaluate prognostic outcomes Researchers may be familiar with the use of Cox proportional hazards (PH) regression to quantify the effect of predictors, such as treatment, imaging, or radiological variables, using hazard ratios. Cox regression requires the proportional hazards assumption, which means that the ratio of hazards between groups is constant over the entire study period, to be valid; however, this scenario is rar
The purposes were to assess the efficacy of AI-generated radiology reports in terms of report summary, patient-friendliness, and recommendations and to evaluate the consistent performance of report quality and accuracy, contributing to the advancement of radiology workflow. Total 685 spine MRI reports were retrieved from our hospital database. AI-generated radiology reports were generated in three formats: (1) summary reports, (2) patient-friendly reports, and (3) recommendations. The occurrence
OBJECTIVES: The aim of this study was to compare the major imaging features of hepatocellular carcinoma (HCC) on magnetic resonance imaging (MRI) scans with Gd-EOB-DTPA (EOB) and extracellular agent (ECA; Gd-DTPA) contrast media. MATERIALS AND METHODS: Among 184 surgically proven HCCs in 169 patients who underwent a liver MRI with either EOB (n = 120) or ECA (n = 49), 55 HCCs were matched according to tumor size, Edmonson grade (major and worst), and gross type for each of the 2 contrast media.
The inter-reader agreement is a key imaging interpretation-related outcome parameter in radiological research.The interpretation of medical images can be affected by the subjective assessment of readers.Therefore, the measure of inter-reader agreement is crucial.A substantial degree of reliability is required in clinical research involving image interpretation.To evaluate the extent of inter-reader agreement, measures of agreement such as kappa, intraclass correlation coefficient (ICC), and conc
Most guidelines for the diagnosis and management of thyroid nodules have suggested fine-needle aspiration as a diagnostic tool, with some of these previously published guidelines suggesting a cutoff size of 1.5 cm. In thyroid cancers (1-2 cm), we hypothesized that tumors 1.5 cm or larger had more unfavorable clinical outcomes than ones smaller than 1.5 cm nodules. Using the Surveillance, Epidemiology, and End Results database, we identified 14,117 patients diagnosed with only primary thyroid can
The study aimed to develop and validate whether the computed tomography (CT) radiomics analysis is effective in differentiating cardiac tumors and thrombi. For this retrospective study, a radiomics model was developed on the basis of a training dataset of 192 patients (61.9 ± 13.3 years, 90 men) with cardiac masses detected in cardiac CT from January 2010 to September 2019. We constructed three models for discriminating between a cardiac tumor and a thrombus: a radiomics model, a clinical model,
TNM staging system of differentiated thyroid cancer defines gross strap muscle invasion as T3b stage. However, the impact of strap muscle invasion on disease-specific survival (DSS) remains controversial. To elucidate the survival impact of strap muscle invasion of any degree in thyroid cancers, the Surveillance, Epidemiology, and End Results (SEER) database (1973-2018) was queried for thyroid cancer only patients on July 2019 (n = 19,914). The Cox proportional hazard analysis with multivariable
This review article presents an assessment of trends in statistical methods and an evaluation of their appropriateness in articles published in the Archives of Plastic Surgery (APS) from 2012 to 2017. We reviewed 388 original articles published in APS between 2012 and 2017. We categorized the articles that used statistical methods according to the type of statistical method, the number of statistical methods, and the type of statistical software used. We checked whether there were errors in the
PURPOSE: We aimed to assess imaging findings and detection sensitivity for melanoma liver metastases on gadoxetic acid-enhanced magnetic resonance imaging (MRI). METHODS: This retrospective study included patients with melanoma liver metastasis who underwent gadoxetic acid-enhanced MRI. Two abdominal radiologists independently evaluated signal characteristics of liver metastases on morphologic imaging (precontrast T1- and T2-weighted imaging), diffusion-weighted imaging (DWI), dynamic imaging, a
산중식 경도 (YA, MPa)와 관입식 경도 Cone index (PE, MPa) 의 측정치를 토양특성이 다른 16개 지점에서 비교해 본 결과, 다음과 같은 회귀식을 구할 수 있었다. <TEX>$$PE=YA^*1.80+0.16(R^2=0.91^{***},N=16)$$</TEX> 이 회귀식의 적용범위는 산중식경도 0.1 MPa 이상 1.3 MPa 이하, mm 단위로 8.0 mm 이상 24.5 mm 이하였다. This study was conducted in order to compare between Yamanaka hardness (YA), hand-push type, and penetrometer cone index (PE), on 16 upland sites. Yamanaka hardness had significant correlation with penetrometer cone index. The regression equation was <TEX>$PE=1.80^*YA+0.
PURPOSE: To confirm that the image quality of coronary computed tomography (CT) angiography with a low tube voltage (80 to 100 kVp), iterative reconstruction, and low-concentration contrast agents (iodixanol 270 to 320 mgI/mL) was not inferior to that with conventional high tube voltage (120 kVp) and high-concentration contrast agent (iopamidol 370 mgI/mL). MATERIALS AND METHODS: This prospective, multicenter, noninferiority, randomized trial enrolled a total of 318 patients from 8 clinical site
This review article presents an assessment of trends in statistical methods and an evaluation of their appropriateness in articles published in the Archives of Plastic Surgery (APS) from 2012 to 2017. We reviewed 388 original articles published in APS between 2012 and 2017. We categorized the articles that used statistical methods according to the type of statistical method, the number of statistical methods, and the type of statistical software used. We checked whether there were errors in the
Water-dispersible Clay Content in Summer Rainy Season for Korean Irrigated Rice Paddy Fields as Affected by Cultivated Years Using Heavy Agro-machinery and Soil Properties-Agro-machinery,Exchangeable sodium percentage,Middleton’s method,Paddy soil,Water-dispersibility of clay
Research Areas
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