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Kyung Min Park

Sungkyunkwan University · Medicine

About the Lab

Professor Kyung Min Park's research lab specializes in cardiovascular electrophysiology and cardiac biomarker dynamics, with a focus on understanding the mechanisms underlying arrhythmias, particularly atrial fibrillation, in both athletic and clinical populations. The lab investigates electrocardiographic predictors of arrhythmia recurrence, the impact of exercise on cardiac stress markers, and the role of autonomic nervous system modulation in cardiac remodeling. Utilizing advanced machine learning techniques applied to serial ECG data, the lab aims to improve early detection and risk stratification of new-onset atrial fibrillation. Their work bridges clinical cardiology with data-driven diagnostics, particularly in high-risk populations such as marathon runners and patients with hypertrophic cardiomyopathy.

atrial fibrillationelectrocardiographycardiac biomarkersmachine learningexercise-induced cardiac stress

Research Overview

Papers
152
Total Citations
2,139
Papers (5y)
74
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
74total
2021
2022
2023
2024
2025
Citations per year (5y)
504total
20212022202320242025

Selected Papers

15
1
Article|25 citations·2015
Correlation of Cardiac Markers and Biomarkers With Blood Pressure of Middle‐Aged Marathon Runners
Young‐Joo Kim, Jae Ki Ahn, Kyung‐A Shin, Chul‐Hyun Kim, Yoonhee Lee, Kyoung‐Min Park
SJR Q2Journal of Clinical HypertensionOA

Runners with exercise-induced high blood pressure have recently been reported to exhibit higher levels of cardiac markers, vasoconstrictors, and inflammation. The authors attempted to identify correlations between exercise-related personal characteristics and the levels of biochemical/cardiac markers in marathon runners in this study. Forty healthy runners were enrolled. Blood samples were taken both before and after finishing a full marathon. The change in each cardiac/biochemical marker over t

Cardiology and Cardiovascular MedicineMedicine
2
Article|15 citations·2016
Excessive exercise habits of runners as new signs of hypertension and arrhythmia
Young‐Joo Kim, Chul‐Hyun Kim, Kyoung‐Min Park
SJR Q1International Journal of Cardiology
Cardiology and Cardiovascular MedicineMedicine
3
Article|14 citations·2021
Electrocardiographic predictors of early recurrence of atrial fibrillation
Ji‐Hoon Choi, Hee Jin Kwon, Hye Ree Kim, Seung‐Jung Park, June Soo Kim, Young Keun On, Kyoung‐Min Park
SJR Q3Annals of Noninvasive ElectrocardiologyOA

Abstract Background Electrical cardioversion (ECV) is an effective method for restoring sinus rhythm after atrial fibrillation (AF). However, early recurrence of AF occurs in a significant number of patients after ECV. This study aimed to identify electrocardiographic (ECG) predictors of early AF recurrence after ECV. Methods A total of 272 patients with persistent AF undergoing successful ECV were consecutively enrolled in this study. We investigated clinical, echocardiographic, and ECG data. T

Cardiology and Cardiovascular MedicineMedicine
4
Article|12 citations·2016
Electrical PR Interval Variation Predicts New Occurrence of Atrial Fibrillation in Patients With Frequent Premature Atrial Contractions
Kwang Jin Chun, Jin Kyung Hwang, Seung‐Jung Park, Young Keun On, June Soo Kim, Kyoung‐Min Park
SJR Q3MedicineOA

Atrial fibrillation (AF) is associated with the autonomic nervous system (ANS), and fluctuation of autonomic tone is more prominent in patients with AF. As autonomic tone affects the heart rate (HR), and there is an inverse relationship between HR and PR interval, PR interval variation could be greater in patients with AF than in those without AF. The purpose of this study was to investigate the correlation between PR interval variation and new-onset AF in patients with frequent PACs.We retrospe

Cardiology and Cardiovascular MedicineMedicine
5
Article|12 citations·2016
Atrial Fibrillation in Hypertrophic Cardiomyopathy: Is the Extent of Septal Hypertrophy Important?
Kyoung‐Min Park, Sung Il Im, Eun Kyoung Kim, Sang‐Chol Lee, Seung-jung Park, June Soo Kim, Young Keun On
SJR Q1PLoS ONEOA

Hypertrophic cardiomyopathy (HCM) is a cardiac disease associated with a high incidence of atrial fibrillation (AF). Recent studies have suggested that interventricular septum thickness may influence the risk stratification of patients with AF. We evaluated the effects of septal hypertrophy on morbidity and mortality in patients with HCM. Patients were followed for a median of 6.1 years and were divided into two groups according to the extent of septal hypertrophy. A total of 1,360 HCM patients

Cardiology and Cardiovascular MedicineMedicine
6
Article|11 citations·2024
Machine Learning Algorithm to Predict Atrial Fibrillation Using Serial 12‐Lead ECGs Based on Left Atrial Remodeling
Ji‐Hoon Choi, Sung‐Hee Song, H. Kim, Jongwoo Kim, Jongwoo Kim, Hee Sun Park, JaeHu Jeon, Joong-Sik Hong, Hye Bin Gwag, Sung Ho Lee, Jaichan Lee, Soo Jin Cho
SJR Q1Journal of the American Heart AssociationOA

Background We hypothesized that analysis of serial ECGs could predict new‐onset atrial fibrillation (AF) more accurately than analysis of a single ECG by detecting the subtle cardiac remodeling that occurs immediately before AF occurrence. Our aim in this study was to compare the performance of 2 types of machine learning (ML) algorithms. Methods and Results Standard 12‐lead ECGs of patients selected by cardiologists between January 2010 and May 2021 were used for ML model development. Two ML mo

Cardiology and Cardiovascular MedicineMedicine
7
Article|10 citations·2016
Prediction of early-onset atrial tachyarrhythmia after successful trans-catheter device closure of atrial septal defect
Kyoung‐Min Park, Jin Kyung Hwang, Kwang Jin Chun, Seung‐Jung Park, Young Keun On, June Soo Kim, Seung Woo Park, I‐Seok Kang, Jinyoung Song, June Huh
SJR Q3MedicineOA

Atrial tachyarrhythmia is a well-known long-term complication of atrial septal defect (ASD) in adults, even after successful trans-catheter closure. However, the risk factors for early-onset atrial tachyarrhythmia after trans-catheter closure remain unclear. This retrospective study enrolled adults with secundum ASD undergoing trans-catheter closure from January 2000 to March 2014. We analyzed the clinical characteristics of patients and assessed risk factors for new-onset atrial tachyarrhythmia

Cardiology and Cardiovascular MedicineMedicine
8
Review|10 citations·2024
Possible Mechanisms for Adverse Cardiac Events Caused by Exercise-Induced Hypertension in Long-Distance Middle-Aged Runners: A Review
Young‐Joo Kim, Kyoung‐Min Park
SJR Q1Journal of Clinical MedicineOA

Sudden cardiac death (SCD) is rare among athletes. However, hypertrophic cardiomyopathy is the leading cause of SCD among those <35 years of age. Meanwhile, coronary artery disease (CAD) is the primary SCD cause among those ≥35 years of age. CAD-induced plaque ruptures are believed to be a significant cause of cardiovascular diseases in middle-aged individuals who participate in extreme long-distance running activities such as marathons. A total of 1970 articles related to EIH were identified us

Cardiology and Cardiovascular MedicineMedicine
9
Article|8 citations·2021
Exercise characteristics and incidence of abnormal electrocardiogram response in long‐distance runners with exercise‐induced hypertension
Young‐Joo Kim, So‐Eun Lee, Kyoung‐Min Park
SJR Q2Journal of Clinical HypertensionOA

While long-distance running has important health benefits, chronic elevation of blood pressure during exercise might induce cardiac events and sudden death. This study aimed to investigate characteristics of exercise and incidence of abnormal exercise electrocardiography findings in long-distance runners with exercise-induced hypertension. Long-distance runners (n = 606) underwent a questionnaire survey, history taking, and exercise stress testing, and they were classified into the non-exercise-

Cardiology and Cardiovascular MedicineMedicine
10
Article|7 citations·2021
Catheter ablation for atrial fibrillation in left ventricular assist device
Yu Jin Chung, Jin‐Oh Choi, Kyoung‐Min Park
SJR Q3MedicineOA

INTRODUCTION: Mechanical circulatory support such as the left ventricular assist device (LVAD) has become widely implemented in the treatment of end-stage heart failure, whether as bridge-to-transplant or as destination therapy. The hemodynamic effects of arrhythmia on LVADs and its management are significant in determining the long-term outcome of these patients. Both atrial arrhythmia and ventricular arrhythmia are commonly seen after implantation of the device. There are no strict guidelines,

Biomedical EngineeringEngineering
11
Article|6 citations·2025
Artificial intelligence-enabled electrocardiogram model for predicting heart failure with preserved ejection fraction: a single-center study
David Hong, Sung‐Hee Song, Hye-Young Shin, Minjung Bak, Juwon Kim, Darae Kim, Ju Youn Kim, Jeong Hoon Yang, Seung‐Jung Park, Jin-Oh Choi, Young Keun On, Kyoung‐Min Park
SJR Q1European Heart Journal - Digital HealthOA

Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is difficult to diagnose due to the lack of a definitive diagnostic marker; multiple tests are required, including advanced evaluations. This study aimed to develop an artificial intelligence (AI)-enabled electrocardiogram (ECG) model for predicting HFpEF. Methods and results This retrospective cohort study included patients from a single tertiary centre who underwent echocardiography, N-terminal prohormone of B-type natriureti

Cardiology and Cardiovascular MedicineMedicine
12
Article|6 citations·2021
Radiofrequency vs. Cryoballoon vs. Thoracoscopic Surgical Ablation for Atrial Fibrillation: A Single-Center Experience
Hee Jin Kwon, Ji‐Hoon Choi, Hye Ree Kim, Seung‐Jung Park, Dong Seop Jeong, Young Keun On, June Soo Kim, Kyoung‐Min Park
SJR Q2MedicinaOA

Background and Objectives: Cryoballoon ablation (CBA) and totally thoracoscopic surgical ablation (TTA) have emerged as alternatives to radiofrequency catheter ablation (RFCA) for atrial fibrillation. In this study, we describe our experience comparing patient characteristics and outcomes of RFCA, CBA, and TTA. Materials and Methods: We retrospectively analyzed data from patients who underwent RFCA, CBA, or TTA. Both atrial fibrillation (AF)- and atrial tachyarrhythmia (ATa)-free survival rates

Cardiology and Cardiovascular MedicineMedicine
13
Article|5 citations·2024
Impact of Premature Ventricular Complex Burden on Ischemic Stroke in Patients with Non-Valvular Atrial Fibrillation
Ju-Won Kim, Ju Youn Kim, Seung‐Jung Park, Young Keun On, Kyoung‐Min Park
SJR Q1Journal of Clinical MedicineOA

Background/Objectives: Limited data are available regarding the prognostic impact of premature ventricular complex (PVC) burden in patients with atrial fibrillation (AF). We sought to compare clinical outcomes in patients with AF according to PVC burden via 24 h Holter monitoring. Methods: From January 2010 to December 2020, 4834 oral anticoagulant (OAC)-naïve non-valvular AF (NVAF) patients who underwent 24 h Holter monitoring were included for analysis. Results: Among the 4834 OAC-naïve NVAF p

Cardiology and Cardiovascular MedicineMedicine
14
Article|5 citations·2018
Frequent atrial premature complexes during exercise: A potent predictor of atrial fibrillation
Jin Kyung Hwang, Hye Bin Gwag, Seung‐Jung Park, Young Keun On, June Soo Kim, Kyoung‐Min Park
SJR Q2Clinical CardiologyOA

BACKGROUND: The clinical significance of atrial premature complexes (APCs) during exercise is unclear. HYPOTHESIS: Frequent APCs during exercise provides prognostic information. METHODS: A total of 998 patients were divided into 2 groups based on the presence of frequent APCs during treadmill testing (>5 beats per stage): the FAPC group (n = 128) vs the non-FAPC group (n = 870). The primary outcome was new-onset atrial fibrillation or flutter (AF/AFL) during follow-up period (356.2 ± 131.1 days)

Cardiology and Cardiovascular MedicineMedicine
15
Article|4 citations·2011
Recurrent polymorphic ventricular tachycardia treated by ablation of Purkinje arborization within an infarct border-zone.
Kyoung‐Min Park, Gi‐Byoung Nam, Kee‐Joon Choi, You-Ho Kim
PubMedOA

A 70-year-old patient with 3-vessel coronary artery disease and a left ventricular aneurysm underwent coronary artery bypass grafting, together with a surgical anterior ventricular endocardial restoration (SAVER) procedure. Four days later, he suddenly developed recurrent sustained and nonsustained polymorphic ventricular tachycardia, preceded by monomorphic ventricular premature contractions, and did not respond to any antiarrhythmic drug, including lidocaine, esmolol, or amiodarone. Repeated e

Cardiology and Cardiovascular MedicineMedicine

Research Areas

Cardiology and Cardiovascular MedicineSurgeryBiomedical EngineeringOphthalmologyInternal MedicineCellular and Molecular Neuroscience

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