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Kyung Rae Ko

Sungkyunkwan University · Medicine

About the Lab

Professor Kyung Rae Ko's research lab specializes in orthopedic surgery and trauma, with a strong focus on improving surgical outcomes through advanced techniques and precise surgical planning. The lab investigates the optimization of bleeding control in total joint arthroplasty using tranexamic acid, evaluates the efficacy of robotic-assisted and conventional implantation in hip and knee replacements, and explores accurate methods for predicting and correcting limb length discrepancies. Additionally, the lab contributes to improving diagnostic accuracy in musculoskeletal conditions through ultrasound-guided interventions and evidence-based surgical decision-making.

joint arthroplastylimb length discrepancyrobot-assisted surgeryultrasound-guided aspirationtranexamic acid

Research Overview

Papers
48
Total Citations
745
Papers (5y)
17
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
17total
2020
2021
2022
2024
2025
Citations per year (5y)
97total
20202021202220242025

Selected Papers

15
1
Article|226 citations·2012
The comparative efficacies of intra‐articular and IV tranexamic acid for reducing blood loss during total knee arthroplasty
Jai‐Gon Seo, Young‐Wan Moon, Sang Hoon Park, Sang‐Min Kim, Kyung Rae Ko
SJR Q1Knee Surgery Sports Traumatology Arthroscopy

PURPOSE: Reduction in blood loss during surgery stabilizes hemodynamic status and aids in recovery after total knee arthroplasty (TKA). In this study, the authors examined whether different administration routes of tranexamic acid (TNA) might affect the amount of blood loss after TKA. METHODS: A total of 150 patients were prospectively allocated to each of the three groups (intravenous, intra-articular, and placebo group) and underwent unilateral TKA. During closing the operative wound, TNA (1.5

BiochemistryMedicine
2
Article|61 citations·2012
Cementless Modular Total Hip Arthroplasty in Patients Younger than Fifty with Femoral Head Osteonecrosis: Minimum Fifteen-Year Follow-Up
Sang‐Min Kim, Seung‐Jae Lim, Young‐Wan Moon, Yang‐Tae Kim, Kyung Rae Ko, Youn-Soo Park
SJR Q1The Journal of Arthroplasty
Orthopedics and Sports MedicineMedicine
3
Article|57 citations·2015
Robot-assisted primary cementless total hip arthroplasty with a short femoral stem: a prospective randomized short-term outcome study
Seung‐Jae Lim, Kyung Rae Ko, Chan-Woo Park, Young‐Wan Moon, Youn-Soo Park
Computer Aided SurgeryOA

The present study suggested that robot-assisted short stem THA could increase the accuracy of stem alignment, improve leg length equality, and help reduce the risk of intraoperative femoral fracture as compared with manual rasping. However, the clinical outcome scores did not differ between the two groups at the time of short-term follow-up. Long-term follow-up is needed to determine whether there will be a long-term clinical relevance of robot-assisted implantation of short femoral stems in THA

SurgeryMedicine
4
Article|48 citations·2013
The accuracy of current methods in determining the timing of epiphysiodesis
S. C. Lee, Jong Sup Shim, Sung Wook Seo, Kyung Sup Lim, Kyung Rae Ko
SJR Q1The Bone & Joint Journal

We compared the accuracy of the growth remaining method of assessing leg-length discrepancy (LLD) with the straight-line graph method, the multiplier method and their variants. We retrospectively reviewed the records of 44 patients treated by percutaneous epiphysiodesis for LLD. All were followed up until maturity. We used the modified Green-Anderson growth-remaining method (Method 1) to plan the timing of epiphysiodesis. Then we presumed that the other four methods described below were used pre

EpidemiologyMedicine
5
Article|43 citations·2018
Repair of only anterior talofibular ligament resulted in similar outcomes to those of repair of both anterior talofibular and calcaneofibular ligaments
Kyung Rae Ko, Won‐Young Lee, Hyobeom Lee, Hee Seol Park, Ki-Sun Sung
SJR Q1Knee Surgery Sports Traumatology Arthroscopy

PURPOSE: To compare the surgical outcomes of the two different ankle stabilization techniques. METHODS: This randomized controlled trial aimed to compare the outcomes of the modified Broström procedure with [calcaneofibular ligament (CFL) group] or without CFL repair [anterior talofibular ligament (ATFL) only group]. Of the 50 patients randomly assigned to two groups, 43 were followed up prospectively for ≥ 2 years (CFL group: 22 patients, 36.6 ± 13.1 months; ATFL Only group: 21 patients, 35.3 ±

Orthopedics and Sports MedicineMedicine
6
Article|35 citations·2006
Value of repeat ultrasound-guided fine-needle aspiration in nodules with benign cytological diagnosis
Jung Hee Shin, Boo‐Kyung Han, Kyung Rae Ko, Yeon Hyeon Choe, Young Lyun Oh
SJR Q3Acta Radiologica

PURPOSE: To assess the value of repeat ultrasound-guided fine-needle aspiration (US-FNA) in nodules with benign cytological diagnosis. MATERIAL AND METHODS: One-hundred-and-eighty-seven patients undergoing repeat US-FNA were included after a benign cytological diagnosis had been made by the initial US-FNA. They were divided into a re-aspiration group, who underwent repeat US-FNA within 6 months for a discordant pathological and clinico-radiological result, and a follow-up aspiration group, who u

OncologyMedicine
7
Article|31 citations·2019
Surgical Results of Limb Lengthening at the Femur, Tibia, and Humerus in Patients with Achondroplasia
Kyung Rae Ko, Jong Sup Shim, Chae Hoon Chung, Joo Hwan Kim
SJR Q1Clinics in Orthopedic SurgeryOA

Humeral lengthening was relatively effective and safe. Careful attention will be needed to avoid the occurrence of limb length discrepancy or malalignment in crossed lengthening.

EpidemiologyMedicine
8
Article|29 citations·2009
MAGNETIC RESONANCE IMAGING OF THE CANINE BRAIN AT 7 T
Byeong‐Teck Kang, Kyung Rae Ko, Dong‐Pyo Jang, Jae‐Yong Han, CHAE‐YOUNG LIM, Chul Park, Jong‐Hyun Yoo, J. H. Kim, Dong‐In Jung, Young-Bo Kim, Eung‐Je Woo, Zang‐Hee Cho
SJR Q1Veterinary Radiology & Ultrasound

The purpose of this study was to describe relevant canine brain structures as seen on T2-weighted images following magnetic resonance (MR) imaging at 7 T and to compare the results with imaging at 1.5 T. Imaging was performed on five healthy laboratory beagle dogs using 1.5 and 7 T clinical scanners. At 1.5 T, spin echo images were acquired, while gradient echo images were acquired at 3 T. Image quality and conspicuity of anatomic structures were evaluated qualitatively by direct comparison of t

Radiology, Nuclear Medicine and ImagingMedicine
9
Article|25 citations·2013
Surgical outcome of desmoid tumors: Adjuvant radiotherapy delayed the recurrence, but did not affect long‐term outcomes
Seung Han Shin, Kyung Rae Ko, Samuel K. Cho, Yoon‐La Choi, Sung Wook Seo
SJR Q1Journal of Surgical Oncology

BACKGROUND: We retrospectively reviewed the outcomes of desmoid tumor (DT) patients treated by surgical excision. METHODS: Among 155 consecutive patients, 119 patients satisfied our inclusion criteria. The mean follow-up duration was 82 months. Age, gender, location, size, depth, resection margin, adjuvant radiotherapy, and excision history were analyzed for the outcomes. RESULTS: The recurrence-free survival (RFS) rates were 75% at 5 years and 72% at 10 years. Twenty-seven (93.1%) out of 29 rec

RheumatologyMedicine
10
Review|21 citations·2022
Substance P, A Promising Therapeutic Target in Musculoskeletal Disorders
Kyung Rae Ko, Hyun Il Lee, Soo-Hong Han, Wooyeol Ahn, Hyung Kyung Kim, Il-Su Kim, Bo Sung Jung, Soonchul Lee
SJR Q1International Journal of Molecular SciencesOA

A large number of studies have focused on the role of substance P (SP) and the neurokinin-1 receptor (NK1R) in the pathogenesis of a variety of medical conditions. This review provides an overview of the role of the SP-NK1R pathway in the pathogenesis of musculoskeletal disorders and the evidence for its role as a therapeutic target for these disorders, which are major public health problems in most countries. To summarize, the brief involvement of SP may affect tendon healing in an acute injury

Cellular and Molecular NeuroscienceNeuroscience
11
Article|20 citations·2019
Clinical and Radiographic Characteristics of Atypical Slipped Capital Femoral Epiphysis
Chae Hoon Chung, Kyung Rae Ko, Joo Hwan Kim, Jong Sup Shim
SJR Q2Journal of Pediatric Orthopaedics

BACKGROUND: Slipped capital femoral epiphysis (SCFEs) can be idiopathic or atypical (associated with renal failure, radiation therapy, and endocrine disorders). It is important to estimate the likelihood that atypical SCFE shows different clinical and radiographic characteristics and complications with typical SCFEs. METHODS: We retrospectively reviewed 53 patients (66 hips) with SCFEs managed between 1995 and 2016. Sex, age, weight, height, the duration of symptoms the laterality of the slip, a

SurgeryMedicine
12
Article|18 citations·2015
Surgical Outcomes After Excision of Pigmented Villonodular Synovitis Localized to the Ankle and Hindfoot Without Adjuvant Therapy
Ki-Sun Sung, Kyung Rae Ko
SJR Q2The Journal of Foot & Ankle Surgery
RheumatologyMedicine
13
Article|17 citations·2006
The axillopectoral muscle seen on mammography
Kyung Rae Ko, Boo‐Kyung Han, Jung Hee Shin, Yeon Hyeon Choe, Hye Won Chung, Eun‐Ho Lee, Soojeong Choi
SJR Q2Clinical Radiology
PhysiologyMedicine
14
Article|15 citations·2018
Ankle strength is not strongly associated with postural stability in patients awaiting surgery for chronic lateral ankle instability
Kyung Rae Ko, Hyobeom Lee, Won-Young Lee, Ki-Sun Sung
SJR Q1Knee Surgery Sports Traumatology Arthroscopy

PURPOSE: (1) To describe ankle strength and postural stability in patients with chronic lateral ankle instability and (2) to analyse the correlation between deficits in ankle strength and postural stability. METHODS: Results of preoperative isokinetic and balance tests in 203 patients whose contralateral ankle was normal were retrospectively reviewed. Isokinetic peak torque values of eversion and inversion at 2 angular velocities (30°/s and 120°/s) were measured in the injured and normal ankles.

Orthopedics and Sports MedicineMedicine
15
Article|14 citations·2022
Substance P Inhibitor Promotes Tendon Healing in a Collagenase-Induced Rat Model of Tendinopathy
Kyung Rae Ko, Soo-Hong Han, Sujin Choi, Hyun‐Ju An, Eun-Bee Kwak, Yunhui Jeong, Minjung Baek, Jusung Lee, Junwon Choi, Il-Su Kim, Soonchul Lee
SJR Q1The American Journal of Sports Medicine

BACKGROUND: The substance P-neurokinin 1 receptor pathway has been proposed as a therapeutic target for tendinopathy. However, there is a lack of evidence regarding its practical applications. PURPOSE: To investigate the therapeutic effects of substance P inhibitor (SPI) on inflamed tenocytes in vitro and in a collagenase-induced rat model of tendinopathy in vivo. STUDY DESIGN: Controlled laboratory study. METHODS: We analyzed the mRNA levels of inflammatory (cyclooxygenase [COX]-2 and interleuk

Orthopedics and Sports MedicineMedicine

Research Areas

SurgeryOrthopedics and Sports MedicineOncologyPhysiologyEpidemiologyGenetics

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