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Kyung‐A Ko

Yonsei University · Dentistry

About the Lab

Professor Kyung-A Ko's research lab specializes in oral and maxillofacial regenerative medicine, with a primary focus on guided bone regeneration (GBR), alveolar ridge augmentation, and the clinical application of biomaterials such as platelet-rich fibrin (PRF), collagen membranes, and natural extracts. The lab investigates tissue engineering strategies to enhance bone formation and soft tissue stability following tooth extraction or implant placement, integrating histomorphometric, micro-CT, and clinical outcome analyses. A key research direction involves evaluating novel therapeutic agents—like mangosteen and propolis extracts—for their anti-inflammatory and regenerative potential in periodontal disease. The lab also explores surgical protocols, including immediate versus delayed implant loading and apically positioned flaps with collagen matrices, to optimize long-term prosthetic outcomes.

guided bone regenerationalveolar ridge augmentationplatelet-rich fibrinperiodontal regenerationimplant dentistry

Research Overview

Papers
21
Total Citations
333
Papers (5y)
13
Primary Field
Dentistry

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2021
2022
2024
2025
2026
Citations per year (5y)
123total
20212022202420252026

Selected Papers

15
1
Article|97 citations·1990
Systematic variation in myosin expression along extraocular muscle fibres of the adult rat
J. Jacoby, Kyung‐A Ko, C. Weiß, Julie Ivory Rushbrook
SJR Q3Journal of Muscle Research and Cell Motility
NeurologyNeuroscience
2
Article|56 citations·1994
Identification of alpha-cardiac myosin heavy chain mRNA and protein in extraocular muscle of the adult rabbit
Julie Ivory Rushbrook, C. Weiß, Kyung‐A Ko, Miriam H. Feuerman, Stephen Carleton, A. Ing, J. Jacoby
SJR Q3Journal of Muscle Research and Cell Motility
Cardiology and Cardiovascular MedicineMedicine
3
Article|25 citations·2022
Effect of collagen membrane fixation on ridge volume stability and new bone formation following guided bone regeneration
Jin‐Young Park, Young Woo Song, Kyung‐A Ko, Franz Josef Strauß, Daniel S. Thoma, Jung‐Seok Lee
SJR Q1Journal Of Clinical PeriodontologyOA

AIM: To test the effect of membrane fixation on ridge volume stability and new bone formation using guided bone regeneration. MATERIALS AND METHODS: In eight beagle dogs, after bilateral extraction of the maxillary pre-molars, a box-shaped defect was created on each side. All defect sites were augmented with a particulate bone substitute material, covered with either one of two non-cross-linked collagen membranes (CM1 or CM2) with or without fixation (-F or -UF). Samples were collected after 8 w

UrologyMedicine
4
Article|24 citations·1993
Sarcoplasmic reticulum fast CA(2+)-pump and myosin heavy chain expression in extraocular muscles.
J. Jacoby, Kyung‐A Ko
PubMed

PURPOSE: To investigate the distribution of the sarcoplasmic reticulum fast-twitch Ca(2+)-pump (Ca(2+)-adenosine triphosphatase [Ca(2+)-ATPase]) in extraocular muscle fiber populations of the rat and rabbit, using fast Ca(2+)-adenosine triphosphatase-specific monoclonal antibodies. METHODS: Adult female rats and rabbits were killed with overdose of sodium pentobarbital, and the extraocular muscles were rapidly frozen in isopentane cooled with liquid nitrogen. Serial transverse frozen sections we

RheumatologyMedicine
5
Article|24 citations·2021
Clinical and Immunological Efficacy of Mangosteen and Propolis Extracted Complex in Patients with Gingivitis: A Multi-Centered Randomized Controlled Clinical Trial
Jin‐Young Park, Kyung‐A Ko, Jiyeong Lee, Yoogyeong Oh, Hyun‐Chang Lim, Dong‐Woon Lee, Seong‐Ho Choi, Jae‐Kook Cha
SJR Q1NutrientsOA

BACKGROUND: Mangosteen and propolis extracts (MAEC) have been potential therapeutic agents known to exhibit powerful antioxidant and anti-inflammatory properties. The aim of the current study was to evaluate the clinical and immunological efficacy of MAEC as well as safety and patient-reported outcomes (PROMs) on gingivitis and incipient periodontitis. METHODS: This study was performed on 104 patients diagnosed with gingivitis or incipient periodontitis. At baseline, the participants were random

Insect ScienceAgricultural and Biological Sciences
6
Article|15 citations·2020
Changes in mucogingival junction after an apically positioned flap with collagen matrix at sites with or without previous guided bone regeneration: A prospective comparative cohort study
Kyung‐A Ko, Jung‐Seok Lee, Jang‐Hyun Kim, Ji‐Man Park, Reinhard Gruber, Daniel S. Thoma
SJR Q1Clinical Oral Implants ResearchOA

AIM: To assess changes in the position of the mucogingival junction (MGJ) after an apically positioned flap (APF) with collagen matrix performed at sites with or without previous guided bone regeneration (GBR). MATERIALS AND METHODS: Dental implants were placed with or without GBR (group GBR or non-GBR) depending on the available ridge width in 30 patients with a limited width of keratinized mucosa (MGJ placed more coronally than the expected prosthetic margin). An apically positioned flap with

Oral SurgeryDentistry
7
Article|15 citations·2022
Platelet‐rich fibrin combined with a particulate bone substitute versus guided bone regeneration in the damaged extraction socket: An in vivo study
Jin‐Young Park, Kyu‐Jin Hong, Kyung‐A Ko, Jae‐Kook Cha, Reinhard Gruber, Jung‐Seok Lee
SJR Q1Journal Of Clinical PeriodontologyOA

AIM: It has been proposed that platelet-rich fibrin (PRF) can be used to support bone regeneration during alveolar ridge augmentation. The aim of this study was to determine whether an approach utilizing PRF provides similar performance to the established guided bone regeneration (GBR) procedure. MATERIALS AND METHODS: Two-wall defects were surgically created in beagle dogs and treated in three experimental groups: (i) a sticky bone (SB) substitute prepared using liquid PRF and deproteinized por

UrologyMedicine
8
Article|13 citations·2021
Immediate loading protocols increase the risk of failure of implants placed by fully guided surgery in partially edentulous jaws: A randomized clinical trial
Kyung‐A Ko, Young Woo Song, Ji‐Man Park, Young‐Bum Park, Chang‐Sung Kim, Jung‐Seok Lee
SJR Q1Clinical Implant Dentistry and Related ResearchOA

AIM: To compare the 1-year outcomes of immediate loading (IL) and delayed loading (DL) protocols for implants placed by fully guided surgery in partially edentulous jaws. MATERIALS AND METHODS: This study included 72 patients who received implant surgery with either IL (93 implants, 36 patients) or DL (94 implants, 26 patients). A prefabricated provisional prosthesis was delivered immediately for the IL group (86 implants, 32 patients) with the exception of 4 subjects in whom an initial torque o

Oral SurgeryDentistry
9
Article|12 citations·2019
Randomized controlled clinical trial on calcium phosphate coated and conventional SLA surface implants: 1‐year study on survival rate and marginal bone level
Kyung‐A Ko, Seungmin Kim, Seong‐Ho Choi, Jung‐Seok Lee
SJR Q1Clinical Implant Dentistry and Related ResearchOA

BACKGROUND: Calcium phosphate (CaP)-coated surface showed enhanced contact osteogenesis around dental implant and finally accelerate osseointegration in early healing phase. PURPOSE: The aim of this randomized controlled trial was to compare the peri-implant marginal bone level around uncoated and CaP-coated sandblasted, large-grit, acid-etched (SLA) surface implants during the first year after placement. MATERIALS AND METHODS: This study was performed upon 34 patients with randomized and double

Oral SurgeryDentistry
10
Article|12 citations·2022
The Impact of Masticatory Function on Cognitive Impairment in Older Patients: A Population-Based Matched Case-Control Study
Kyung‐A Ko, Jin‐Young Park, Jung‐Seok Lee, Byoung Seok Ye, Ui‐Won Jung, Seong‐Ho Choi, Jae‐Kook Cha
SJR Q2Yonsei Medical JournalOA

There might be a causative relationship between the neglected missing dentition and the onset of dementia.

Speech and HearingHealth Professions
11
Article|12 citations·2024
Risk of post-operative bleeding after dentoalveolar surgery in patients taking anticoagulants: a cohort study using the common data model
Jooyeon Lee, Seunghyun Park, Da-Mi Kim, Kyung‐A Ko, Jin‐Young Park, Jung‐Seok Lee, Ui‐Won Jung, Jae‐Kook Cha
SJR Q1Scientific ReportsOA

This retrospective study aimed to determine risk factors associated with post-operative bleeding after dentoalveolar surgery in patients taking anticoagulants. Patients taking anticoagulants who were planned to undergo periodontal flap operation, tooth extraction or implant surgery were included. Patients were divided into two subgroups according to the maintenance of anticoagulants following medical consultation: (1) maintenance group and (2) discontinuation group. The analysed patient-related

Cardiology and Cardiovascular MedicineMedicine
12
Article|9 citations·2025
Patient‐Centred Preferences for Autonomy and Information‐Seeking Among Periodontal Patients in Dental Decision Making
Ji‐Young Jung, Kyung‐A Ko, Franz Josef Strauß, Jae‐Hong Lee, Jae‐Hong Lee, Junhewk Kim, Jung‐Seok Lee, Jung‐Seok Lee
SJR Q1Journal Of Clinical PeriodontologyOA

BACKGROUND AND AIM: Managing periodontal disease often involves complex decisions involving multiple treatment options, and patient autonomy significantly influences this decision-making process. This study aimed to characterise the autonomy and information-seeking preferences among patients diagnosed with stage III/IV periodontitis, and to identify the factors influencing these preferences. MATERIALS AND METHODS: The survey included 96 patients diagnosed with periodontal disease, all of whom un

General Health ProfessionsHealth Professions
13
Article|5 citations·2025
Particulate Versus Cross‐Linked Collagenated Bone Substitutes for Guided Bone Regeneration: A Randomized Controlled Trial
Ji‐Young Jung, Seung‐Hyun Park, K. Kim, Kyung‐A Ko, Dong‐Woon Lee, Jung‐Seok Lee
SJR Q1Clinical Oral Implants ResearchOA

AIM: To compare the dimensional outcomes of horizontal augmentation with the retentive-flap technique using particulate and cross-linked collagenated bone substitutes. MATERIALS AND METHODS: This two-centre, two-arm randomized clinical trial investigated 69 subjects: 34 in the particulate group and 35 in the collagenated group. Patients were randomly assigned to receive single implant placement with simultaneous guided bone regeneration (GBR) using either particulate deproteinized porcine bone m

Oral SurgeryDentistry
14
Article|4 citations·1969
Treatment of femoral neck fractures
W Kawaji, Kyung‐A Ko
SJR Q1Injury
SurgeryMedicine
15
Article|3 citations·2025
Association between dental care and improvement in long‐term care dependency levels in Korean beneficiaries
Bo‐Ah Lee, Jung Kyu Choi, Kyung‐A Ko, Jung‐Seok Lee, Young‐Taek Kim
SJR Q2Geriatrics and gerontology international/Geriatrics & gerontology international

Aim Although it has been reported that poor oral health is associated with worsening general health, oral health has been given less importance than general health in Long‐Term Care (LTC) insurance beneficiaries. The aim of this study was to evaluate the association between dental care and improvement in dependency levels of LTC insurance beneficiaries. Methods This study collected data from 53 130 beneficiaries who were newly approved for LTC in Korea in 2015. They were assigned to five LTC lev

PeriodonticsDentistry

Research Areas

Oral SurgeryUrologyPeriodonticsCardiology and Cardiovascular MedicineGeneral Health ProfessionsNeurology

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