Skip to main content

Min-kyung Kim

Ewha Womans University · Biochemistry, Genetics and Molecular Biology

About the Lab

Professor Min-kyung Kim's research lab specializes in computational systems biology and bioinformatics, focusing on genome-scale metabolic modeling, particularly in microalgae such as *Phaeodactylum tricornutum*. The lab develops advanced computational methods to infer intracellular metabolic fluxes from transcriptomic data, integrating multi-omics data to predict metabolic phenotypes and support synthetic biology applications. A key research direction involves leveraging machine learning and systems-level modeling to understand and optimize metabolic networks for sustainable biofuel production.

metabolic modelingtranscriptomicssystems biologybiofuelsflux inference

Research Overview

Papers
512
Total Citations
8,684
Papers (5y)
112
Primary Field
Biochemistry, Genetics and Molecular Biology

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
112total
2022
2023
2024
2025
2026
Citations per year (5y)
594total
20222023202420252026

Selected Papers

15
1
Article|213 citations·2018
Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations
Stanley Chun-Wei Lee, Khrystyna North, Eun Hee Kim, Eunjung Jang, Esther A. Obeng, Sydney X. Lu, Bo Liu, Daichi Inoue, Akihide Yoshimi, Michelle Ki, Mirae Yeo, Xiao Jing Zhang
SJR Q1Cancer CellOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
Article|154 citations·2017
Lexical Sophistication as a Multidimensional Phenomenon: Relations to Second Language Lexical Proficiency, Development, and Writing Quality
Minkyung Kim, Scott A. Crossley, Kristopher Kyle
SJR Q1Modern Language JournalOA

Abstract This study conceptualizes lexical sophistication as a multidimensional phenomenon by reducing numerous lexical features of lexical sophistication into 12 aggregated components (i.e., dimensions) via a principal component analysis approach. These components were then used to predict second language (L2) writing proficiency levels, holistic lexical proficiency scores, and longitudinal lexical growth. The results from regression analyses indicated that 5 lexical components (i.e., bigram an

Developmental and Educational PsychologyPsychology
3
Article|128 citations·2018
Modeling second language writing quality: A structural equation investigation of lexical, syntactic, and cohesive features in source-based and independent writing
Minkyung Kim, Scott A. Crossley
SJR Q1Assessing WritingOA
Developmental and Educational PsychologyPsychology
4
Article|93 citations·2017
Analyzing the Impact of Nuclear Power on CO2 Emissions
S. Lee, Minkyung Kim, Jiwoong Lee
SJR Q1SustainabilityOA

This study investigates the relationship between the nuclear power proportion and CO2 emissions per capita using the panel dynamic ordinary least square method. The panel datasets consist of 18 countries covering 95% of the global nuclear reactors. The results indicate that a long-term 1% increase in nuclear power led to a 0.26–0.32% decrease in CO2 emissions per capita. Additionally, in France, Germany, and Switzerland they demonstrate the existence of the environmental Kuznets curve—an inverte

Economics and EconometricsEconomics, Econometrics and Finance
5
Article|92 citations·2018
Effect of fabrication parameters on surface roughness of FDM parts
Min Kyung Kim, In Hwan Lee, Ho-Chan Kim
SJR Q2International Journal of Precision Engineering and Manufacturing
Automotive EngineeringEngineering
6
Review|88 citations·2014
Methods for integration of transcriptomic data in genome-scale metabolic models
Min Kyung Kim, Desmond S. Lun
SJR Q1Computational and Structural Biotechnology JournalOA

Several computational methods have been developed that integrate transcriptomic data with genome-scale metabolic reconstructions to infer condition-specific system-wide intracellular metabolic flux distributions. In this mini-review, we describe each of these methods published to date with categorizing them based on four different grouping criteria (requirement for multiple gene expression datasets as input, requirement for a threshold to define a gene's high and low expression, requirement for

Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
Article|86 citations·2021
Attribute Sentiment Scoring with Online Text Reviews: Accounting for Language Structure and Missing Attributes
Ishita Chakraborty, Minkyung Kim, K. Sudhir
SJR Q1Journal of Marketing Research

The authors address two significant challenges in using online text reviews to obtain fine-grained, attribute-level sentiment ratings. First, in contrast to methods that rely on word frequency, they develop a deep learning convolutional–long short-term memory hybrid model to account for language structure. The convolutional layer accounts for spatial structure (adjacent word groups or phrases), and long short-term memory accounts for the sequential structure of language (sentiment distributed an

Artificial IntelligenceComputer Science
8
Article|82 citations·2015
Flux balance analysis of primary metabolism in the diatom Phaeodactylum tricornutum
Joomi Kim, Michele Fabris, Gino Baart, Min Kyung Kim, Alain Goossens, Wim Vyverman, Paul G. Falkowski, Desmond S. Lun
SJR Q1The Plant JournalOA

Diatoms (Bacillarophyceae) are photosynthetic unicellular microalgae that have risen to ecological prominence in oceans over the past 30 million years. They are of interest as potential feedstocks for sustainable biofuels. Maximizing production of these feedstocks will require genetic modifications and an understanding of algal metabolism. These processes may benefit from genome-scale models, which predict intracellular fluxes and theoretical yields, as well as the viability of knockout and knoc

Renewable Energy, Sustainability and the EnvironmentEnergy
9
Article|73 citations·2016
E-Flux2 and SPOT: Validated Methods for Inferring Intracellular Metabolic Flux Distributions from Transcriptomic Data
Min Kyung Kim, Anatoliy Lane, James J. Kelley, Desmond S. Lun
SJR Q1PLoS ONEOA

Our method represents a significant advance over existing methods for inferring intracellular metabolic flux from transcriptomic data. It not only achieves higher accuracy, but it also combines into a single method a number of other desirable characteristics including applicability to a wide range of experimental conditions, production of a unique solution, fast running time, and the availability of a user-friendly implementation.

Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
Article|73 citations·2015
Task-based Language Learning – Insights from and for L2 Writing
Minkyung Kim
SJR Q1System
Language and LinguisticsArts and Humanities
11
Article|71 citations·2013
Microstructures and electrochemical performances of nano-sized SiOx (1.18 ≤ x ≤ 1.83) as an anode material for a lithium(Li)-ion battery
Min Kyung Kim, Bo Yun Jang, Jin Seok Lee, Joon Soo Kim, Sahn Nahm
SJR Q1Journal of Power Sources
Electrical and Electronic EngineeringEngineering
12
Article|68 citations·2021
Genome-wide association study identifies QTL for eight fruit traits in cultivated tomato (Solanum lycopersicumL.)
Minkyung Kim, Thuy Tien Phan Nguyen, Joon-Hyung Ahn, Gi-Jun Kim, Sung‐Chur Sim
SJR Q1Horticulture ResearchOA

Abstract Genome-wide association study (GWAS) is effective in identifying favorable alleles for traits of interest with high mapping resolution in crop species. In this study, we conducted GWAS to explore quantitative trait loci (QTL) for eight fruit traits using 162 tomato accessions with diverse genetic backgrounds. The eight traits included fruit weight, fruit width, fruit height, fruit shape index, pericarp thickness, locule number, fruit firmness, and brix. Phenotypic variations of these tr

GeneticsBiochemistry, Genetics and Molecular Biology
13
Article|65 citations·2011
The effect of clozapine on the AMPK-ACC-CPT1 pathway in the rat frontal cortex
Min Kyung Kim, Se Hyun Kim, Hyun Sook Yu, Hong Geun Park, Ung Gu Kang, Yong Min Ahn, Yong Sik Kim
SJR Q1The International Journal of NeuropsychopharmacologyOA

Clozapine is an antipsychotic drug that has a greater efficacy than other medications in some contexts, especially for the treatment of treatment-resistant schizophrenia. However, clozapine induces more metabolic side-effects involving abnormality in lipid metabolism compared to other antipsychotics. AMP-activated protein kinase (AMPK) plays a central role in controlling lipid metabolism through modulating the downstream acetyl CoA carboxylase (ACC) and carnitine palmitoyl transferase 1 (CPT1) p

Molecular BiologyBiochemistry, Genetics and Molecular Biology
14
Article|56 citations·2011
Simultaneous determination of chromones and coumarins in Radix Saposhnikoviae by high performance liquid chromatography with diode array and tandem mass detectors
Min Kyung Kim, Dong-Hyug Yang, Mihye Jung, Eun Ha Jung, Han Young Eom, Joon Hyuk Suh, Jung Won Min, Unyong Kim, Hyeyoung Min, Jinwoong Kim, Sang Beom Han
SJR Q1Journal of Chromatography A
Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
Article|50 citations·2019
When Salespeople Manage Customer Relationships: Multidimensional Incentives and Private Information
Minkyung Kim, K. Sudhir, Kosuke Uetake, Rodrigo Canales
SJR Q1Journal of Marketing Research

At many firms, incentivized salespeople with private information about customers are responsible for customer relationship management. Although incentives motivate sales performance, private information can induce moral hazard by salespeople to gain compensation at the expense of the firm. The authors investigate the sales performance–moral hazard trade-off in response to multidimensional performance (acquisition and maintenance) incentives in the presence of private information. Using unique pa

Organizational Behavior and Human Resource ManagementBusiness, Management and Accounting

Research Areas

Molecular BiologyInformation SystemsMarketingArtificial IntelligenceDevelopmental and Educational PsychologyPlant Science

Dive deeper into Min-kyung Kim's research on Nubint

Open this lab's papers in the app to read with AI, summarize, and cite in your writing.