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Myung-Ji Lee

Yonsei University · Medicine

About the Lab

Professor Myung-Ji Lee's research lab focuses on epidemiological and environmental health studies, particularly investigating the impact of early-life exposures—such as air pollution, birth weight, and maternal behaviors—on long-term health outcomes in children and adults. The lab specializes in population-based cohort studies to explore associations between prenatal and early childhood factors and conditions like atopic dermatitis, obesity, and cancer risk. Their work integrates environmental exposures, genetic factors, and lifestyle behaviors to identify modifiable risk and protective factors.

early-life exposureepidemiologyenvironmental healthcohort studychildhood health

Research Overview

Papers
79
Total Citations
890
Papers (5y)
52
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
52total
2022
2023
2024
2025
2026
Citations per year (5y)
332total
20222023202420252026

Selected Papers

15
1
Article|89 citations·2020
A Single-Center Retrospective Analysis of Periprocedural Variables Affecting Local Tumor Progression after Radiofrequency Ablation of Colorectal Cancer Liver Metastases
Kichang Han, Jin Hyoung Kim, Seul Gi Yang, Seong Ho Park, Hyun‐Kyung Choi, Seng-Yong Chun, Pyo Nyun Kim, Jihong Park, Myeongjee Lee
SJR Q1Radiology

Background Local tumor progression (LTP) is associated with poorer survival in patients undergoing radiofrequency ablation (RFA) for colorectal liver metastasis (CLM). An algorithmic strategy to predict LTP may help in selection of patients who would benefit most from RFA for CLM. Purpose To estimate local tumor progression-free survival (LTPFS) following RFA of CLM and develop an algorithmic strategy based on clinical variables. Materials and Methods In this retrospective study, between March 2

HepatologyMedicine
2
Article|67 citations·2019
The Protective Effect of Exclusive Breastfeeding on Overweight/Obesity in Children with High Birth Weight
Jung Won Lee, Myeongjee Lee, Jueun Lee, Young Ju Kim, Eun‐Hee Ha, Hae Soon Kim
SJR Q2Journal of Korean Medical ScienceOA

BACKGROUND: A positive association between birth weight (BW) and body mass index (BMI) has been shown among children in many populations. The aim of this study was to investigate BMI trajectory according to BW status and the protective effect of breastfeeding on the prevalence of overweight/obesity in children 6 years of age. METHODS: A retrospective cohort study was conducted between January 1, 2008 and December 31, 2016 utilizing data from the National Health Information Database of Korea. The

Pediatrics, Perinatology and Child HealthMedicine
3
Article|62 citations·2018
Preventive Effect of Residential Green Space on Infantile Atopic Dermatitis Associated with Prenatal Air Pollution Exposure
Ji-Young Lee, Dirga Kumar Lamichhane, Myeongjee Lee, Shinhee Ye, Jung-Hyun Kwon, Myung‐Sook Park, Hwan‐Cheol Kim, Jong‐Han Leem, Yun‐Chul Hong, Yangho Kim, Mina Ha, Eun‐Hee Ha
SJR Q2International Journal of Environmental Research and Public HealthOA

Few birth cohort studies have examined the role of traffic-related air pollution (TRAP) in the development of infantile atopic dermatitis (AD), but none have investigated the role of preventive factors such as green spaces. The aim of this study was to investigate whether exposure to nitrogen dioxide (NO2) and particulate matter with an aerodynamic diameter of <10 μm (PM10) during pregnancy is associated with increased risk of development of AD in 6-month-old children and also to examine how

Health, Toxicology and MutagenesisEnvironmental Science
4
Article|60 citations·2021
Impact of the COVID-19 pandemic on mental health service use among psychiatric outpatients in a tertiary hospital
Jun Ho Seo, Se Joo Kim, Myeongjee Lee, Jee In Kang
SJR Q1Journal of Affective DisordersOA
Clinical PsychologyPsychology
5
Article|50 citations·2019
Exposure to prenatal secondhand smoke and early neurodevelopment: Mothers and Children’s Environmental Health (MOCEH) study
Myeongjee Lee, Mina Ha, Yun‐Chul Hong, Hyesook Park, Yangho Kim, Eui‐Jung Kim, Yeni Kim, Eun‐Hee Ha
SJR Q1Environmental HealthOA

Maternal exposure to SHS during pregnancy may result in delayed MDI in early childhood. This effect might be modified by genetic polymorphism and breastfeeding behavior.

Health, Toxicology and MutagenesisEnvironmental Science
6
Article|47 citations·2022
Periodontal disease and cancer risk: A nationwide population-based cohort study
Eun Hwa Kim, Sunghyun Nam, Chung Hyun Park, Yitak Kim, Myeongjee Lee, Joong Bae Ahn, Sang Joon Shin, Yu Rang Park, Hoi‐In Jung, Baek‐Il Kim, Inkyung Jung, Han Sang Kim
SJR Q2Frontiers in OncologyOA

Background Although emerging evidence suggests that periodontitis might increase the risk of cancer, comorbidity and lifestyle behaviors, such as smoking and body mass index (BMI), may have confounded this reported association. This study aimed to investigate whether chronic periodontitis is associated with cancer risk using a large, nationwide database. Methods We conducted a population-based, retrospective cohort study using data from the Korean National Health Insurance Cohort Database obtain

PeriodonticsDentistry
7
Article|42 citations·2019
Association of Long-term Use of Low-Dose Aspirin as Chemoprevention With Risk of Lung Cancer
Shinhee Ye, Myeongjee Lee, Dongheon Lee, Eun‐Hee Ha, Eun Mi Chun
SJR Q1JAMA Network OpenOA

Although the use of low-dose aspirin for more than 5 years was associated with decreased risk of lung cancer, particularly among elderly participants and among people without diabetes, the observed effect size was quite modest. Future prospective studies are needed to determine whether there is a causal association.

PharmacologyMedicine
8
Article|40 citations·2020
MRI Ancillary Features for LI-RADS Category 3 and 4 Observations: Improved Categorization to Indicate the Risk of Hepatic Malignancy
Yeun‐Yoon Kim, Jin‐Young Choi, Seung Up Kim, Myeongjee Lee, Mi‐Suk Park, Yong Eun Chung, Myeong‐Jin Kim
SJR Q1American Journal of RoentgenologyOA

<b>OBJECTIVE.</b> The purpose of this study was to investigate whether ancillary features can help stratify malignancy risk in Liver Imaging Reporting and Data System (LI-RADS) category 3 (LR-3) and 4 (LR-4) observations. <b>MATERIALS AND METHODS.</b> This retrospective longitudinal study included 106 LR-3 or LR-4 observations on gadolinium-enhanced MRI obtained from January 2014 to December 2015 in 80 patients who were treatment naïve and at risk (mean age, 58.0 ± 10.7 [SD] years; 60 men). The

HepatologyMedicine
9
Article|39 citations·2023
Effects of heavy metal exposure during pregnancy on birth outcomes
Sabrina Shafi Zinia, Ki-Hyeok Yang, Eun Ju Lee, Myoung-Nam Lim, Jeeyoung Kim, Woo Jin Kim, Woo Jin Kim, Choong-Hee Park, Hyun Jeong Kim, Soon-Won Jung, Sooyeon Hong, A-Ra Jung
SJR Q1Scientific ReportsOA

Exposure to heavy metals such as lead, cadmium, and mercury poses serious health risks to pregnant women because of their high toxicity. In this study, we investigated the associations of heavy metal exposure with birth outcomes of Korean infants. Data of 5,215 women between 2015 and 2019 were analyzed. This study was part of the Korean Children's Environmental Health (Ko-CHENS) study. Linear regression and logistic regression analyses were used to examine effects of concentrations of lead, cadm

Health, Toxicology and MutagenesisEnvironmental Science
10
Article|37 citations·2020
An optimized hepatocellular carcinoma prediction model for chronic hepatitis B with well‐controlled viremia
Hye Won Lee, Soo Y. Park, Myeongjee Lee, Eun Jig Lee, Jinae Lee, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Beom Kyung Kim
SJR Q1Liver InternationalOA

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) risk in chronic hepatitis B (CHB) substantially decreased in the era of potent antiviral therapy. We developed an optimized HCC risk prediction model for CHB with well-controlled viremia by nucelos(t)ide analogs (NUCs). METHOD: We analysed those who achieved virological response (VR; serum HBV-DNA < 2000 IU/mL on two consecutive assessments) by NUCs. Liver stiffness by transient elastography, ultrasonography and laboratory tests was performed a

EpidemiologyMedicine
11
Article|28 citations·2023
Restless leg syndrome and risk of all-cause dementia: a nationwide retrospective cohort study
Keun You Kim, Eun Hwa Kim, Myeongjee Lee, Jung-Hee Ha, Inkyung Jung, Eosu Kim
SJR Q1Alzheimer s Research & TherapyOA

BACKGROUND: Restless leg syndrome (RLS) is associated with poor sleep quality, depression or anxiety, poor dietary patterns, microvasculopathy, and hypoxia, all of which are known risk factors for dementia. However, the relationship between RLS and incident dementia remains unclear. This retrospective cohort study aimed to explore the possibility that RLS could be deemed as a non-cognitive prodromal feature of dementia. METHODS: This was a retrospective cohort study using the Korean National Hea

EpidemiologyMedicine
12
Article|27 citations·2022
Respiratory Syncytial Virus Outbreak Without Influenza in the Second Year of the Coronavirus Disease 2019 Pandemic: A National Sentinel Surveillance in Korea, 2021–2022 Season
Jong‐Hun Kim, Ha Yan Kim, Myeongjee Lee, Jong Gyun Ahn, Jee Yeon Baek, Min Young Kim, Kyungmin Huh, Jaehun Jung, Ji‐Man Kang
SJR Q2Journal of Korean Medical ScienceOA

During 2021-2022, endemic transmission of the RSV, but not IFV, was observed in Korea.

EpidemiologyMedicine
13
Article|21 citations·2023
Comparison of a Polysaccharide Hemostatic Powder and Conventional Therapy for Peptic Ulcer Bleeding
Da Hyun Jung, Chan-Hyuk Park, Soo In Choi, Hye Rim Kim, Myeongjee Lee, Hee Seok Moon, Jun Chul Park
SJR Q1Clinical Gastroenterology and Hepatology
GastroenterologyMedicine
14
Article|19 citations·2016
Differences in survival for patients with familial and sporadic cancer
Myeongjee Lee, Marie Reilly, Linda S. Lindström, Kamila Czene
SJR Q1International Journal of CancerOA

Family history of cancer is a well-known risk factor but the role of family history in survival is less clear. The aim of this study was to investigate the association between family history and cancer survival for the common cancers in Sweden. Using the Swedish population-based registers, patients diagnosed with the most common cancers were followed for cancer-specific death during 1991-2010. We used multivariate proportional hazards (Cox) regression models to contrast the survival of patients

GeneticsBiochemistry, Genetics and Molecular Biology
15
Review|17 citations·2021
Age-adjusted quick Sequential Organ Failure Assessment score for predicting mortality and disease severity in children with infection: a systematic review and meta-analysis
Sohyun Eun, Haemin Kim, Ha Yan Kim, Myeongjee Lee, Go Eun Bae, Heoungjin Kim, Chung Mo Koo, Moon Kyu Kim, Seo Hee Yoon
SJR Q1Scientific ReportsOA

We assessed the diagnostic accuracy of the age-adjusted quick Sequential Organ Failure Assessment score (qSOFA) for predicting mortality and disease severity in pediatric patients with suspected or confirmed infection. We conducted a systematic search of PubMed, EMBASE, the Cochrane Library, and Web of Science. Eleven studies with a total of 172,569 patients were included in the meta-analysis. The pooled sensitivity, specificity, and diagnostic odds ratio of the age-adjusted qSOFA for predicting

EpidemiologyMedicine

Research Areas

EpidemiologyHealth, Toxicology and MutagenesisPeriodonticsOncologyInfectious DiseasesGenetics

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