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Sae Hee Ra

Yonsei University · Medicine

About the Lab

Professor Sae Hee Ra's research lab specializes in critical care and perioperative medicine, with a focus on optimizing sedation strategies in pediatric and adult patients, particularly through pharmacodynamic modeling of anesthetics like propofol. The lab investigates postoperative complications such as nausea and vomiting, exploring non-pharmacological interventions like P6 acupressure, and examines long-term outcomes following intensive care unit (ICU) discharge. Additionally, the lab addresses quality improvement in ICU practices, including head-of-bed elevation protocols to prevent ventilator-associated pneumonia and the impact of delirium on patient mortality and recovery. Their work bridges clinical anesthesiology, critical care, and patient-centered outcomes research in diverse inpatient populations.

sedationICU outcomespostoperative nauseadeliriumventilator-associated pneumonia

Research Overview

Papers
11
Total Citations
17
Papers (5y)
6
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
6total
2012
2013
2014
2017
2020
Citations per year (5y)
10total
20122013201420172020

Selected Papers

11
1
Article|5 citations·2017
A Simulation Study of Propofol Effect-Site Concentration for Appropriate Sedation in Pediatric Patients Undergoing Brain MRI: Pharmacodynamic Analysis
라세희, 한동우, 송영, 김소연, 변효진, 정환호
https://www.eymj.org/DOIx.php?id=10.3349/ymj.2017.58.6.1216

Purpose: We aimed to establish the propofol effect-site concentration (Ce) for appropriate sedation by pharmacodynamic analysis and to determine the propofol Ce during occurrence of sedation-related side effects in pediatric patients undergoing brain magneticresonance imaging (MRI). Materials and Methods: In 50 pediatric patients scheduled for brain MRI, sedation was induced with 2.0 mg/kg propofol; additionalpropofol doses were 0.5−1 mg/kg. Propofol Ce was simulated by inputting the propofol ad

2
Article|4 citations·2014
국내 일 병원 중환자실에서 관찰한 섬망 환자의 예후
손정현, 박진영, 라세희, 신증수, 손인정, 오주영, 안지선, 안석균, 김재진
http://jknpa.org/

중환자실 재실 중 섬망을 경험하는 환자는 다른 인자들의영향을 통제한 후에도 퇴원시 사망률이 높고, 재실 기간 및입원 기간이 더 길어 본 연구의 가설과 일치하는 결과를 보였다. 이 결과는 국외 연구들에서 보고되어 온 바와 일치하며, 국내 종합병원 중환자실 환경의 환자군을 대상으로 하여그 상관관계를 처음으로 확인하였다는 의의가 있다. 이러한결과는 향후 국내 의료 환경에서 발생하는 섬망에 대한 탐색과 이에 대한 적절한 중재를 연구하는 데 기초 자료로서 활용될 것으로 기대한다.

3
Article|4 citations·2009
갑상선 절제술을 받은 환자에서 P6 Acupressure의 술 후 오심, 구토에 대한 예방 효과
라세희, 김나영, 길혜금

Background: Postoperative nausea and vomiting (PONV) is a common problem in patients recovering from anesthesia and surgery. P6 point is the acupressure point for prevention of postoperative nausea and vomiting. We evaluated the efficacy of acupressure at the P6 point in 94 patients undergoing thyroidectomy in a randomized, prospective and placebo-controlled study. Methods: Ninety-four female patients, aged 18 to 60, scheduled for elective thyroidectomy, were randomized to have either placebo

4
Article|3 citations·2011
환기보조 받는 중환자에서 병상머리 올림 프로토콜 적용이 임상 경과와 경장영양공급에 미치는 효과
라세희, 이호선, 고신옥, 이현심, 나성원

Background: Although head of bed (HOB) elevation is an important strategy to prevent ventilator associated pneumonia (VAP), some observational studies have reported that the application of the semi-recumbent position was lower in patients receiving mechanical ventilator support. We performed this study to assess the effect of implementation of the HOB elevation protocol in the intensive care unit (ICU) on clinical and nutritional outcomes. Methods: We developed a HOB elevation protocol including

5
Article|1 citations·2017
A Preliminary Study on the Circadian Rhythm of Autonomic Nervous System in Patients Admitted to Intensive Care Unit, Using the Heart Rate Variability
오주영, 조동래, 김종인, 박재섭, 허재석, 김재진, 라세희, 신증수, 이보름, JinYeong Bak
Saengmul jeongsin euihag/Saengmul jeongsin uihak
Cardiology and Cardiovascular MedicineMedicine
6
dissertation|0 citations·2008
갑상선 절제술을 받은 환자에서 P6 Acupressure의 술 후 오심, 구토에 대한 예방 효과
라세희, 김나영, Hae-Keum Kil
Aerospace EngineeringEngineering
7
Article|0 citations·2020
Long-term mortality of patients discharged from the hospital after successful critical care in the ICU in Korea: a retrospective observational study in a single tertiary care teaching hospital
라세희, 신증수, 김관호, 김재훈, 이종석

Background: The long-term outcomes of patients discharged from the hospital after successful care in intensive care unit (ICU) are not briskly evaluated in Korea. The aim of this study was to assess long-term mortality of patients treated in the ICU and discharged alive from the hospital and to identify predictive factors of mortality. Methods: In 3,679 adult patients discharged alive from the hospital after ICU care between 2006 and 2011, the 1-year mortality rate (primary outcome measure) was

8
Article|0 citations·2010
Ultrasonic doppler flowmeter-guided occipital nerve block
라세희, 김태원, 오세영, 권태동, 윤경봉, 윤덕미

Background: Greater occipital nerve block is used in the treatment of headaches and neuralgia in the occipital area. We evaluated the efficacy of ultrasonic doppler flowmeter-guided occipital nerve block in patients experiencing headache in the occipital region in a randomized, prospective, placebo-controlled study. Methods: Twenty-six patients, aged 18 to 70, with headache in the occipital region, were included in the study. Patients received a greater occipital nerve block performed either und

9
Article|0 citations·2007
무체외순환 관상동맥 우회술에서 6% Hydroxyethyl starch (HES) 130/0.4와 6% HES 200/0.5가 조직 산소화와 수술 후 출혈에 미치는 영향
김창석, 곽영란, 방서욱, Jae‐Kwang Shim, 라세희, 김대희
Nutrition and DieteticsNursing
10
Article|0 citations·2013
Undiagnosed light chain systemic amyloidosis: does it matter to anesthesiologists?-a case report-
김관호, 이우경, 라세희, 이종석

Light chain systemic amyloidosis is rare but may accompany laryngeal or pulmonary involvement, which may increase the risk in airway management. We present a case of a patient planned for resection of cervical epidural mass. The patient had face and neck ecchymoses and purpuras with an unknown cause. Mask ventilation and intubation were successful, but the operation was cancelled to evaluate bleeding from facial skin lesions. A diagnosis of light chain systemic amyloidosis prompted evaluation of

11
dissertation|0 citations·2012
중환자에서 질병 중증도와 영양 상태가 예후에 미치는 효과
안서희, 라세희, 장철호, 임현선, 이덕철, 신증수

Background: Malnutrition is common in hospitalized patients, especially in critically ill patients and affects their mortality and morbidity. However, the correlation between malnutrition and poor outcome is not fully understood. Our hypothesis is that the nutritional effect on the patient`s prognosis would differ depending on the severity of the disease. Methods: 3,758 patients admitted to the intensive care unit (ICU) were observed retrospectively. Patients were divided into well, moderate and

PhysiologyMedicine

Research Areas

Cardiology and Cardiovascular MedicineNutrition and DieteticsPhysiologyAerospace Engineering

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