Sang Eup Lee
Sungkyunkwan University · Medicine
About the Lab
Professor Sang Eup Lee's research lab focuses on interdisciplinary studies spanning biomedical engineering, clinical pharmacology, and investment behavior analysis. The lab investigates physiological and pharmacological mechanisms in disease models—particularly tuberculosis and spinal cord health—while also exploring behavioral finance through real-world investment data. Key research directions include drug transporter expression in infectious diseases, age-related anatomical changes in the cervical spine, and long-term investment strategies in financial markets. The integration of biological, clinical, and economic data underscores a unique approach to understanding health and decision-making across biological and financial systems.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15BACKGROUD: There are many studies on the vertebral body-to-canal ratio, the so-called Pavlov's ratio of the cervical spine. However, there are no studies on its relation with age to clarify each bony component's contribution to the spinal canal formation and its size. The aim of this study was to investigate differences and changes in the vertebral body-to-canal ratio according to age in an asymptomatic population. METHODS: This is a cross-sectional study of 280 asymptomatic individuals. A total
본 연구는 간접투자시장에서 적립식투자 전략과 거치식투자 전략의 성과를 시뮬레이션 및 실제 투자계좌 데이터를 가지고 분석하여 보다 우월한 투자전략을 찾는데 목적이 있다. 주요 분석결과는 다음과 같다. 첫째, 역사적 시뮬레이션과 몬테카를로 시뮬레이션 결과, 1년 미만의 단기에서는 거치식투자 전략이 우월한 반면, 3년 이상의 장기에서는 적립식투자 전략이 우월한 전략인 것으로 나타났다. 둘째, 실제 투자자의 계좌를 분석한 결과, 적립식투자가 거치식투자에 비해 우월한 성과를 나타내는 것으로 확인되었다. 특히, 위험조정 성과를 기준으로 볼 때 투자기간이 길고 투자금액이 클수록, 적립식투자가 우월한 결과를 나타냈다. 셋째, 적립식투자에 있어서 최종 납입 이후 1개월 후에 기계적으로 환매한 경우와 투자자의 판단에 의해 환매한 경우를 비교해 보면 성과의 유의적인 차이가 없어 적립식 투자자들의 환매시점 선정능력은 없는 것으로 보인다. 넷째, 신규가입 및 환매의 주가에 대한 민감도를 분석해 본 결과 투
A pulmonary tuberculosis mouse model was used to assess the pharmacodynamic and pharmacokinetic characteristics of tuberculosis therapeutics. While membrane transporters play important roles in drug disposition and physiological homeostasis, their expressional changes and contribution have never been analysed in a tuberculosis animal model. The mRNA expression level of 20 Abc family transporters and 32 Slc family transporters in tuberculosis-infected mice were compared with those in naïve uninfe
The present study was conducted to assess the impacts of different water and light intensities on the physiological and the biochemical aspects of cork oak (Quercus suber L.) seedlings from acorns collected from Tabarka (Northern Tunisia). The experiments were divided into two treatments: Water stress (well-watered: 25 to 35%, moderate drought stress: 15 to 20%, and severe drought stress: 7 to 10%) and light intensity stress (full sunlight: 100% of full sunlight, 1,200 μmol m -2 s -1 , moderate
본 연구는 주식형펀드 계좌 데이터를 이용하여 펀드투자자의 연령과 투자성과 사이의 관계를검증하였다. 또한 성별, 투자금액, 펀드유형과 같은 개인별 특성이 펀드투자자의 연령과 투자성과사이의 관계에 미치는 영향을 분석하였다. 횡단면회귀분석을 통해 분석한 결과 첫째, 연령이 높아짐에 따라 투자성과가 증가하며 이는 경제적으로 의미 있는 수준인 것으로 확인되었다. 이러한결과는 펀드투자자의 성과지표를 달리하는 강건성 테스트에서도 유의한 것으로 나타났다. 둘째,펀드투자자의 연령과 투자성과 사이의 양(+)의 상관관계가 남성보다 여성의 경우에 현저하게 크다는것을 발견하였다. 셋째, 펀드투자자의 연령과 투자성과 사이의 양(+)의 상관관계가 투자금액이 큰경우에 더욱 크다는 것을 확인하였다. 마지막으로 펀드투자자의 연령과 투자성과 사이의 양(+)의상관관계는 거치식계좌 보다는 적립식계좌에서 크다는 것을 발견하였다. 위의 결과들은 투자자의사회경제적 경험을 비롯한 개인별 특성이 투자성과에 영향을 미친다는 것을
Adjunctive cilostazol improved clopidogrel responsiveness better than the higher maintenance dose of clopidogrel in hyporesponsive patients with chronic clopidogrel therapy.
It is critical for radiant floor cooling system using Ondol to cause condensation on a floor surface. To solve this problem, a radiant floor cooling system integrated with dehumidification was proposed and evaluated in terms of its applicability and prevention of condensation. Therresults show that the proposed system of radiant floor cooling integrated with dehumidification properly maintained the indoor setpoint temperatures and prevented the condensation on a floor surface. To achieve more st
Design: Study on the cases of the united interlocked intramedullary (IM) nailed humeral shaft fractures. Objective: To assess the healing pattern of nailed humeral shaft fracture and to compare it with the results of the other previous authors’ nail-treated large bone fractures. Background data: Based on the relevant previous studies related with healing patterns of the interlocked IM nail-managed humeral shaft fractures, the current age-matched study on the participating callus for union was co
Background and Objectives: The maze procedure is effective in restoring sinus rhythm (SR) in patients with atrial fibrillation (AF). We compared the left atrial mechanical function (LAMF) of patients whose rhythm was converted to SR after maze procedure with that of patients whose rhythm was not converted to SR and determined if preoperative left atrial volume index (LAVI) and immediate postoperative LAMF could predict conversion of AF to SR. Subjects and Methods: We prospectively evaluated 80 p
The western metaphysics tends to presuppose the center, which results in the Platonic binary opposition such as reality/appearance, soul/body, and mind/material. This binary opposition often leads to a very serious problem of violent hierarchization and differentiation, namely, a structure of oppression and the oppressed. Derrida uses two stages of decon- struction to break up this hierarchical structure. The first stage is intervening in and reversing the hierarchy. For example, when there is a
Research Areas
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